34508096Dutta D, Jana M, Majumder M, Mondal S, Roy A, Pahan KNature communicationsalpha-Synuclein; Dopaminergic Neurons; MicrogliaAnimals; Cells, Cultured; Disease Models, Animal; Humans; Lewy Body Disease; Mice; Mice, Knockout; Multiple System Atrophy; Mutagenesis, Site-Directed; Mutation; Myeloid Differentiation Factor 88; NF-kappa B; Parkinson Disease; Primary Cell Culture; Promoter Regions, Genetic; Signal Transduction; Toll-Like Receptor 2Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo. Nat Commun. 2021 09 10; 12(1):5382.Nat Commun2021-09-10T00:00:002021Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo.Faculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings31945770.519818AnimalsD053594Chemicals & Drugs8130.987716Myeloid Differentiation Factor 88D017628Anatomy321240.912398MicrogliaD016297PhysiologyProcedures17190.995197Mutagenesis, Site-DirectedD020961Disorders25980.909268Lewy Body DiseaseKalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessorSusantaMondalSusanta Mondal349459Mondal, SusantaAssistant Professor6Assistant ProfessorD051379Living Beings18816080.701537MiceD061251Procedures12210.991513Primary Cell CultureD010300Disorders6311640.510774Parkinson DiseaseD051844Chemicals & Drugs251380.867548alpha-SynucleinD011401Chemicals & Drugs44840.969324Promoter Regions, GeneticD059290Anatomy11440.92575Dopaminergic NeuronsD051195Chemicals & Drugs21320.971985Toll-Like Receptor 2D002478Anatomy1306870.866744Cells, CulturedD019578Disorders19420.948748Multiple System AtrophyD015398Physiology1374860.811992Signal TransductionNeurological SciencesRush University, Rush Medical CollegeAuthorship 426934Authorship 429036Authorship 429970.8382080.2095523authors10.2520has subject areaD004195Disorders1597290.77457Disease Models, Animaltrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorD016328Chemicals & DrugsPhysiology401070.949454NF-kappa BD009154Physiology1303830.856385MutationD006801Living Beings643293340.211949HumansD018345Living Beings903030.918645Mice, Knockout