D053707Chemicals & DrugsD12.776.543.750.705.852.420.5804100.985824Receptors, Interleukin-12Faculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonKalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessor24224652Jana M, Mondal S, Jana A, Pahan KImmunologyInterleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology. 2014 Apr; 141(4):549-63.Immunology2014-04-01T00:00:002014Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis.19306359Jana M, Dasgupta S, Pal U, Pahan KGliaIL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia. 2009 Nov 01; 57(14):1553-65.Glia2009-11-01T00:00:002009IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.19100623Jana M, Pahan KMolecular immunologyIL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol. 2009 Feb; 46(5):773-83.Mol Immunol2008-12-18T00:00:002008IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.19587012Brahmachari S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. J Immunol. 2009 Aug 01; 183(3):2045-58.J Immunol2009-07-08T00:00:002009Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide.MalubenduJanaMalubendu Jana349337Jana, MalubenduAssistant ProfessorSusantaMondalSusanta Mondal349459Mondal, SusantaAssistant Professor6Assistant Professor32817415Mondal S, Kundu M, Jana M, Roy A, Rangasamy SB, Modi KK, Wallace J, Albalawi YA, Balabanov R, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaIL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21557-21567.Proc Natl Acad Sci U S A2020-08-19T00:00:002020IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE.Neurological SciencesRush University, Rush Medical College1.780140.08494344research area of0.7788540.08616496subject area fortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant ProfessorJennilleeWallaceJennillee Wallace350107Wallace, JennilleeAssistant ProfessorMicrobial Pathogens and Immunity