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Connection

Anne-Marie Malfait to Animals

This is a "connection" page, showing publications Anne-Marie Malfait has written about Animals.
Connection Strength

2.394
  1. Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain. Arthritis Res Ther. 2023 04 15; 25(1):63.
    View in: PubMed
    Score: 0.134
  2. Pain-related behaviors and abnormal cutaneous innervation in a murine model of classical Ehlers-Danlos syndrome. Pain. 2020 10; 161(10):2274-2283.
    View in: PubMed
    Score: 0.112
  3. Targeting neurotrophic factors: Novel approaches to musculoskeletal pain. Pharmacol Ther. 2020 07; 211:107553.
    View in: PubMed
    Score: 0.109
  4. An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis. Semin Immunopathol. 2019 09; 41(5):583-594.
    View in: PubMed
    Score: 0.105
  5. The nociceptive innervation of the normal and osteoarthritic mouse knee. Osteoarthritis Cartilage. 2019 11; 27(11):1669-1679.
    View in: PubMed
    Score: 0.103
  6. Osteoarthritis pain: What are we learning from animal models? Best Pract Res Clin Rheumatol. 2017 10; 31(5):676-687.
    View in: PubMed
    Score: 0.095
  7. An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI Insight. 2018 03 22; 3(6).
    View in: PubMed
    Score: 0.094
  8. Peripheral Mechanisms Contributing to Osteoarthritis Pain. Curr Rheumatol Rep. 2018 02 26; 20(2):9.
    View in: PubMed
    Score: 0.094
  9. Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging. Arthritis Rheumatol. 2018 01; 70(1):88-97.
    View in: PubMed
    Score: 0.092
  10. Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis. Arthritis Rheumatol. 2017 07; 69(7):1429-1439.
    View in: PubMed
    Score: 0.089
  11. Can we target CCR2 to treat osteoarthritis? The trick is in the timing! Osteoarthritis Cartilage. 2017 06; 25(6):799-801.
    View in: PubMed
    Score: 0.087
  12. Nerve growth factor blockade for the management of osteoarthritis pain: what can we learn from clinical trials and preclinical models? Curr Opin Rheumatol. 2017 01; 29(1):110-118.
    View in: PubMed
    Score: 0.086
  13. Spinal microglial activation in a murine surgical model of knee osteoarthritis. Osteoarthritis Cartilage. 2017 05; 25(5):718-726.
    View in: PubMed
    Score: 0.085
  14. Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis Rheumatol. 2015 Nov; 67(11):2933-43.
    View in: PubMed
    Score: 0.080
  15. Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis Cartilage. 2016 Feb; 24(2):299-306.
    View in: PubMed
    Score: 0.079
  16. Osteoarthritis joint pain: the cytokine connection. Cytokine. 2014 Dec; 70(2):185-93.
    View in: PubMed
    Score: 0.073
  17. Towards a mechanism-based approach to pain management in osteoarthritis. Nat Rev Rheumatol. 2013 Nov; 9(11):654-64.
    View in: PubMed
    Score: 0.069
  18. Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets. Curr Rheumatol Rep. 2013 Aug; 15(8):350.
    View in: PubMed
    Score: 0.068
  19. CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis. Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50):20602-7.
    View in: PubMed
    Score: 0.065
  20. Modelling pain in post-traumatic osteoarthritis of the knee. Pain. 2012 Feb; 153(2):257-258.
    View in: PubMed
    Score: 0.060
  21. Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8). Clin Exp Immunol. 2009 Nov; 158(2):246-56.
    View in: PubMed
    Score: 0.052
  22. Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation. Osteoarthritis Cartilage. 2009 May; 17(5):627-35.
    View in: PubMed
    Score: 0.049
  23. Will the real aggrecanase(s) step up: evaluating the criteria that define aggrecanase activity in osteoarthritis. Curr Pharm Biotechnol. 2008 Feb; 9(1):16-23.
    View in: PubMed
    Score: 0.047
  24. Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage. Arthritis Res Ther. 2024 Dec 20; 26(1):224.
    View in: PubMed
    Score: 0.038
  25. Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee. J Orthop Res. 2025 Mar; 43(3):632-639.
    View in: PubMed
    Score: 0.037
  26. Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes. J Biol Chem. 2004 Apr 23; 279(17):17554-61.
    View in: PubMed
    Score: 0.035
  27. The usual suspects: verdict not guilty? Arthritis Rheum. 2003 Dec; 48(12):3304-7.
    View in: PubMed
    Score: 0.035
  28. Age-Associated Changes in Knee Osteoarthritis, Pain-Related Behaviors, and Dorsal Root Ganglia Immunophenotyping of Male and Female Mice. Arthritis Rheumatol. 2023 10; 75(10):1770-1780.
    View in: PubMed
    Score: 0.034
  29. Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies. Arthritis Rheum. 2001 May; 44(5):1215-24.
    View in: PubMed
    Score: 0.029
  30. The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice. Arthritis Res Ther. 2021 04 07; 23(1):103.
    View in: PubMed
    Score: 0.029
  31. The innate immune response as a mediator of osteoarthritis pain. Osteoarthritis Cartilage. 2020 05; 28(5):562-571.
    View in: PubMed
    Score: 0.027
  32. Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety. Pain. 2019 10; 160(10):2210-2220.
    View in: PubMed
    Score: 0.026
  33. The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action. J Immunol. 1999 May 15; 162(10):6278-83.
    View in: PubMed
    Score: 0.025
  34. Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis. J Orthop Res. 2018 03; 36(3):864-875.
    View in: PubMed
    Score: 0.023
  35. CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy. Osteoarthritis Cartilage. 2017 03; 25(3):406-412.
    View in: PubMed
    Score: 0.021
  36. PCSK6-mediated corin activation is essential for normal blood pressure. Nat Med. 2015 Sep; 21(9):1048-53.
    View in: PubMed
    Score: 0.020
  37. Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthritis Cartilage. 2015 Aug; 23(8):1254-66.
    View in: PubMed
    Score: 0.019
  38. Structure analysis reveals the flexibility of the ADAMTS-5 active site. Protein Sci. 2011 Apr; 20(4):735-44.
    View in: PubMed
    Score: 0.014
  39. An immunoaffinity liquid chromatography-tandem mass spectrometry assay for detection of endogenous aggrecan fragments in biological fluids: Use as a biomarker for aggrecanase activity and cartilage degradation. Anal Biochem. 2010 Nov 15; 406(2):113-23.
    View in: PubMed
    Score: 0.014
  40. Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1). Biochemistry. 2007 May 29; 46(21):6393-401.
    View in: PubMed
    Score: 0.011
  41. Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network. J Biol Chem. 2004 Apr 09; 279(15):15434-40.
    View in: PubMed
    Score: 0.009
  42. Combination therapy with DMARDs and biological agents in collagen-induced arthritis. Clin Exp Rheumatol. 1999 Nov-Dec; 17(6 Suppl 18):S115-20.
    View in: PubMed
    Score: 0.007
  43. Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis. Eur J Immunol. 1999 07; 29(7):2205-12.
    View in: PubMed
    Score: 0.006
  44. Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram. J Immunol. 1997 Dec 15; 159(12):6253-9.
    View in: PubMed
    Score: 0.006
  45. DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis: characterization of the cytokine cascade and cellular composition. J Immunol. 1997 Sep 15; 159(6):2867-76.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.