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Connection

Alan Landay to CD4-Positive T-Lymphocytes

This is a "connection" page, showing publications Alan Landay has written about CD4-Positive T-Lymphocytes.
Connection Strength

7.268
  1. Modulation of TIM-3 expression on NK and T cell subsets in HIV immunological non-responders. Clin Immunol. 2015 Jan; 156(1):28-35.
    View in: PubMed
    Score: 0.433
  2. Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction. AIDS. 2013 Jun 19; 27(10):1563-71.
    View in: PubMed
    Score: 0.394
  3. Serum immune activation markers are persistently increased in patients with HIV infection after 6 years of antiretroviral therapy despite suppression of viral replication and reconstitution of CD4+ T cells. J Infect Dis. 2009 Oct 15; 200(8):1212-5.
    View in: PubMed
    Score: 0.306
  4. The relationship of T-regulatory cell subsets to disease stage, immune activation, and pathogen-specific immunity in HIV infection. J Acquir Immune Defic Syndr. 2008 Aug 15; 48(5):577-80.
    View in: PubMed
    Score: 0.282
  5. Immunophenotypic alterations in acute and early HIV infection. Clin Immunol. 2007 Dec; 125(3):299-308.
    View in: PubMed
    Score: 0.265
  6. The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection. Front Immunol. 2021; 12:695674.
    View in: PubMed
    Score: 0.173
  7. T Lymphocyte Subsets Associated With Prevalent Diabetes in Veterans With and Without Human Immunodeficiency Virus. J Infect Dis. 2020 06 29; 222(2):252-262.
    View in: PubMed
    Score: 0.160
  8. Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA). J Immunol Methods. 2000 Apr 03; 237(1-2):187-97.
    View in: PubMed
    Score: 0.158
  9. Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs. J Acquir Immune Defic Syndr. 2019 12 15; 82(5):503-513.
    View in: PubMed
    Score: 0.155
  10. Regulation of CCR5 and CXCR4 expression by type 1 and type 2 cytokines: CCR5 expression is downregulated by IL-10 in CD4-positive lymphocytes. Clin Immunol. 1999 Jun; 91(3):254-62.
    View in: PubMed
    Score: 0.149
  11. Cytokine modulation of HIV-1 chemokine receptor expression. Nat Med. 1999 Jun; 5(6):592-3.
    View in: PubMed
    Score: 0.149
  12. Small differences in CD4+ T-cell production may go unnoticed. AIDS. 1999 Feb 04; 13(2):290-1.
    View in: PubMed
    Score: 0.146
  13. Induction of HIF-1a by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. mBio. 2018 09 11; 9(5).
    View in: PubMed
    Score: 0.142
  14. Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals. Front Immunol. 2018; 9:900.
    View in: PubMed
    Score: 0.139
  15. Function and phenotype of immature CD4+ lymphocytes in healthy infants and early lymphocyte activation in uninfected infants of human immunodeficiency virus-infected mothers. Clin Diagn Lab Immunol. 1997 May; 4(3):358-61.
    View in: PubMed
    Score: 0.129
  16. Brief Report: CD14brightCD16- monocytes and sCD14 level negatively associate with CD4-memory T-cell frequency and predict HCV-decline on therapy. J Acquir Immune Defic Syndr. 2016 11 01; 73(3):258-262.
    View in: PubMed
    Score: 0.125
  17. CD4+ lymphocytes in perinatal human immunodeficiency virus (HIV) infection: evidence for pregnancy-induced immune depression in uninfected and HIV-infected women. J Infect Dis. 1995 Nov; 172(5):1221-7.
    View in: PubMed
    Score: 0.116
  18. Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection. Mucosal Immunol. 2016 Jan; 9(1):24-37.
    View in: PubMed
    Score: 0.112
  19. Association of chronic hepatitis C infection with T-cell phenotypes in HIV-negative and HIV-positive women. J Acquir Immune Defic Syndr. 2014 Nov 01; 67(3):295-303.
    View in: PubMed
    Score: 0.108
  20. Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. PLoS One. 2014; 9(4):e92934.
    View in: PubMed
    Score: 0.104
  21. The relation of plasmacytoid dendritic cells (pDCs) and regulatory T-cells (Tregs) with HPV persistence in HIV-infected and HIV-uninfected women. Viral Immunol. 2014 Feb; 27(1):20-5.
    View in: PubMed
    Score: 0.103
  22. Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. AIDS. 2014 Jan 28; 28(3):297-309.
    View in: PubMed
    Score: 0.103
  23. A rapid manual method for CD4+ T-cell quantitation for use in developing countries. AIDS. 1993 Dec; 7(12):1565-8.
    View in: PubMed
    Score: 0.102
  24. Characterization of CD4? T-cell immune activation and interleukin 10 levels among HIV, hepatitis C virus, and HIV/HCV-coinfected patients. J Acquir Immune Defic Syndr. 2013 Nov 01; 64(3):232-40.
    View in: PubMed
    Score: 0.101
  25. Association of HIV clinical disease progression with profiles of early immune activation: results from a cluster analysis approach. AIDS. 2013 Jun 01; 27(9):1473-81.
    View in: PubMed
    Score: 0.098
  26. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 2013 Jun 06; 121(23):4635-46.
    View in: PubMed
    Score: 0.097
  27. GB virus C infection is associated with altered lymphocyte subset distribution and reduced T cell activation and proliferation in HIV-infected individuals. PLoS One. 2012; 7(11):e50563.
    View in: PubMed
    Score: 0.095
  28. Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection. J Infect Dis. 2012 Sep 01; 206(5):780-9.
    View in: PubMed
    Score: 0.092
  29. CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies. J Infect Dis. 2012 Jun; 205(11):1730-8.
    View in: PubMed
    Score: 0.090
  30. HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy. AIDS. 2011 Jan 14; 25(2):159-64.
    View in: PubMed
    Score: 0.083
  31. Intracellular Casp8p41 content is inversely associated with CD4 T cell count. J Infect Dis. 2010 Aug 15; 202(3):386-91.
    View in: PubMed
    Score: 0.081
  32. CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. J Infect Dis. 2008 May 15; 197(10):1402-7.
    View in: PubMed
    Score: 0.069
  33. HIV infection of primary CD4+ Th2 cells, defined by expression of the chemoattractant receptor-homologous (CRTH2), induces a Th0 phenotype. AIDS Res Hum Retroviruses. 2007 Feb; 23(2):269-77.
    View in: PubMed
    Score: 0.063
  34. Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection. J Virol. 2006 Oct; 80(20):10162-72.
    View in: PubMed
    Score: 0.062
  35. Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study. J Infect Dis. 2006 Oct 15; 194(8):1098-107.
    View in: PubMed
    Score: 0.062
  36. Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J Infect Dis. 2006 Jul 01; 194(1):29-37.
    View in: PubMed
    Score: 0.060
  37. Evaluating the impact of hepatitis C virus (HCV) on highly active antiretroviral therapy-mediated immune responses in HCV/HIV-coinfected women: role of HCV on expression of primed/memory T cells. J Infect Dis. 2006 May 01; 193(9):1202-10.
    View in: PubMed
    Score: 0.060
  38. HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections. Am J Clin Pathol. 2006 Mar; 125(3):386-91.
    View in: PubMed
    Score: 0.059
  39. Depletion of latent HIV-1 infection in vivo: a proof-of-concept study. Lancet. 2005 Aug 13-19; 366(9485):549-55.
    View in: PubMed
    Score: 0.057
  40. Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection. Clin Diagn Lab Immunol. 2005 May; 12(5):622-31.
    View in: PubMed
    Score: 0.056
  41. Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells. Immunology. 2005 Mar; 114(3):322-35.
    View in: PubMed
    Score: 0.055
  42. Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells. Blood. 2004 Jun 15; 103(12):4581-7.
    View in: PubMed
    Score: 0.052
  43. Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients. HIV Med. 2004 Jan; 5(1):55-65.
    View in: PubMed
    Score: 0.051
  44. T cell activation is insufficient to drive SIV disease progression. JCI Insight. 2023 07 24; 8(14).
    View in: PubMed
    Score: 0.050
  45. Correlates of immune activation marker changes in human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women who use illicit drugs. J Infect Dis. 2003 Jul 15; 188(2):209-18.
    View in: PubMed
    Score: 0.049
  46. Interleukin-2 Increases CD4+ lymphocyte numbers but does not enhance responses to immunization: results of A5046s. J Infect Dis. 2003 Jan 15; 187(2):320-5.
    View in: PubMed
    Score: 0.048
  47. Entrapment of recent thymic emigrants in lymphoid tissues from HIV-infected patients: association with HIV cellular viral load. AIDS. 2002 Nov 08; 16(16):2119-27.
    View in: PubMed
    Score: 0.047
  48. Immune recovery in HIV disease: role of the thymus and T cell expansion in immune reconstitution strategies. J Hematother Stem Cell Res. 2002 Oct; 11(5):777-86.
    View in: PubMed
    Score: 0.047
  49. Sex Differences in Human Immunodeficiency Virus Persistence and Reservoir Size During Aging. Clin Infect Dis. 2022 08 24; 75(1):73-80.
    View in: PubMed
    Score: 0.047
  50. CCR5 and CXCR4 expression after highly active antiretroviral therapy (HAART). J Acquir Immune Defic Syndr. 2002 Aug 01; 30(4):458-60.
    View in: PubMed
    Score: 0.046
  51. Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study. Atherosclerosis. 2022 06; 351:18-25.
    View in: PubMed
    Score: 0.046
  52. Circulating CD4+ TEMRA and CD4+ CD28- T cells and incident diabetes among persons with and without HIV. AIDS. 2022 03 15; 36(4):501-511.
    View in: PubMed
    Score: 0.045
  53. T-Cell Immune Dysregulation and Mortality in Women With Human Immunodeficiency Virus. J Infect Dis. 2022 02 15; 225(4):675-685.
    View in: PubMed
    Score: 0.045
  54. Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection. Nat Med. 2002 Jan; 8(1):47-53.
    View in: PubMed
    Score: 0.045
  55. Persistence of intracellular HIV-1 mRNA correlates with HIV-1-specific immune responses in infected subjects on stable HAART. AIDS. 2001 Sep 07; 15(13):1635-41.
    View in: PubMed
    Score: 0.044
  56. Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2001 Sep 01; 17(13):1231-40.
    View in: PubMed
    Score: 0.044
  57. Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells. Immunology. 2001 Jul; 103(3):270-80.
    View in: PubMed
    Score: 0.043
  58. Association of Monocyte Migration Marker CD11b With Pulmonary Function in People Living With HIV. J Acquir Immune Defic Syndr. 2021 03 01; 86(3):344-352.
    View in: PubMed
    Score: 0.042
  59. Food Insecurity and T-cell Dysregulation in Women Living With Human Immunodeficiency Virus on Antiretroviral Therapy. Clin Infect Dis. 2021 03 01; 72(5):e112-e119.
    View in: PubMed
    Score: 0.042
  60. Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption. mBio. 2021 02 23; 12(1).
    View in: PubMed
    Score: 0.042
  61. Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: age inversely predicts naive CD4 cell count increase. AIDS. 2000 Dec 01; 14(17):2635-42.
    View in: PubMed
    Score: 0.041
  62. Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy. J Infect Dis. 2020 11 09; 222(11):1837-1842.
    View in: PubMed
    Score: 0.041
  63. Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and na?ve phenotypes. Clin Immunol. 2000 Nov; 97(2):95-101.
    View in: PubMed
    Score: 0.041
  64. A look at HIV immune research. Interview by Alan Huff. Res Initiat Treat Action. 2000 Sep; 6(3):30-3.
    View in: PubMed
    Score: 0.041
  65. Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers. Clin Infect Dis. 2020 04 10; 70(8):1636-1642.
    View in: PubMed
    Score: 0.040
  66. Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response. J Infect Dis. 2000 Jan; 181(1):358-63.
    View in: PubMed
    Score: 0.039
  67. Delayed gastrointestinal-associated lymphoid tissue reconstitution in duodenum compared with rectum in HIV-infected patients initiating antiretroviral therapy. AIDS. 2019 12 01; 33(15):2289-2298.
    View in: PubMed
    Score: 0.039
  68. Increases in T cell telomere length in HIV infection after antiretroviral combination therapy for HIV-1 infection implicate distinct population dynamics in CD4+ and CD8+ T cells. Clin Immunol. 1999 Jul; 92(1):14-24.
    View in: PubMed
    Score: 0.037
  69. Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy. J Leukoc Biol. 2018 09; 104(3):461-471.
    View in: PubMed
    Score: 0.034
  70. Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study. Obstet Gynecol. 1997 Jun; 89(6):967-74.
    View in: PubMed
    Score: 0.032
  71. Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression. J Virol. 2017 03 15; 91(6).
    View in: PubMed
    Score: 0.032
  72. Immunological effects of antiretroviral and immune therapies for HIV. AIDS. 1997; 11 Suppl A:S149-55.
    View in: PubMed
    Score: 0.031
  73. Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin. AIDS. 1996 Jun; 10(6):603-11.
    View in: PubMed
    Score: 0.030
  74. In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10. J Infect Dis. 1996 May; 173(5):1085-91.
    View in: PubMed
    Score: 0.030
  75. The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):163-71.
    View in: PubMed
    Score: 0.030
  76. Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):172-80.
    View in: PubMed
    Score: 0.030
  77. A matched cross-sectional study of the association between circulating tissue factor activity, immune activation and advanced liver fibrosis in hepatitis C infection. BMC Infect Dis. 2015 Apr 17; 15:190.
    View in: PubMed
    Score: 0.028
  78. Older age is associated with peripheral blood expansion of na?ve B cells in HIV-infected subjects on antiretroviral therapy. PLoS One. 2014; 9(9):e107064.
    View in: PubMed
    Score: 0.027
  79. Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication. J Clin Invest. 2014 Jun; 124(6):2802-6.
    View in: PubMed
    Score: 0.026
  80. Prediction of CD4 count from CD4 percentage: experience from three laboratories. AIDS. 1993 Jul; 7(7):933-40.
    View in: PubMed
    Score: 0.025
  81. Interferon-alpha administration enhances CD8+ T cell activation in HIV infection. PLoS One. 2012; 7(1):e30306.
    View in: PubMed
    Score: 0.022
  82. T cell activation predicts carotid artery stiffness among HIV-infected women. Atherosclerosis. 2011 Jul; 217(1):207-13.
    View in: PubMed
    Score: 0.021
  83. Analysis of lymphocytes, monocytes, and neutrophils from human immunodeficiency virus (HIV)-infected persons for HIV DNA. J Infect Dis. 1990 Dec; 162(6):1239-44.
    View in: PubMed
    Score: 0.021
  84. Circulating human immunodeficiency virus (HIV) p24 antigen-positive lymphocytes: a flow cytometric measure of HIV infection. J Infect Dis. 1990 Nov; 162(5):1018-24.
    View in: PubMed
    Score: 0.021
  85. Isolation of HIV-1 from monocytes of individuals negative by conventional culture. J Infect Dis. 1990 Apr; 161(4):706-10.
    View in: PubMed
    Score: 0.020
  86. Absolute number versus percentage of T-helper lymphocytes in human immunodeficiency virus infection. J Infect Dis. 1990 Feb; 161(2):356-7.
    View in: PubMed
    Score: 0.020
  87. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood. 2009 Jun 18; 113(25):6304-14.
    View in: PubMed
    Score: 0.018
  88. Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis. 2009 Apr 15; 199(8):1177-85.
    View in: PubMed
    Score: 0.018
  89. GBV-C viremia is associated with reduced CD4 expansion in HIV-infected people receiving HAART and interleukin-2 therapy. AIDS. 2009 Mar 13; 23(5):605-10.
    View in: PubMed
    Score: 0.018
  90. Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells. AIDS. 2008 Jun 19; 22(10):1131-5.
    View in: PubMed
    Score: 0.017
  91. Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology. 2007 Sep; 122(1):1-14.
    View in: PubMed
    Score: 0.016
  92. Saliva can mediate HIV-1-specific antibody-dependent cell-mediated cytotoxicity. FEMS Immunol Med Microbiol. 2006 Nov; 48(2):267-73.
    View in: PubMed
    Score: 0.015
  93. Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway. Virology. 2006 Jul 05; 350(2):443-52.
    View in: PubMed
    Score: 0.015
  94. Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection. J Infect Dis. 2003 Dec 15; 188(12):1804-14.
    View in: PubMed
    Score: 0.013
  95. MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study. J Acquir Immune Defic Syndr. 2003 Nov 01; 34(3):295-8.
    View in: PubMed
    Score: 0.013
  96. Immune reconstitution after successful treatment with protease inhibitor-based and protease inhibitor-sparing antiretroviral regimens. J Acquir Immune Defic Syndr. 2002 Apr 15; 29(5):544-5.
    View in: PubMed
    Score: 0.011
  97. T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals. AIDS. 2001 Sep 28; 15(14):1757-64.
    View in: PubMed
    Score: 0.011
  98. Anti-CCR5 antibodies in sera of HIV-positive individuals. Hum Immunol. 2001 Feb; 62(2):143-5.
    View in: PubMed
    Score: 0.010
  99. Altered viral fitness of HIV-1 following failure of protease inhibitor-based therapy. J Acquir Immune Defic Syndr. 2000 Dec 01; 25(4):289-95.
    View in: PubMed
    Score: 0.010
  100. Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. J Infect Dis. 2000 Jan; 181(1):141-7.
    View in: PubMed
    Score: 0.010
  101. Multiple patterns of alloantigen presenting/stimulating cell dysfunction in patients with AIDS. J Immunol. 1991 Apr 01; 146(7):2207-13.
    View in: PubMed
    Score: 0.005
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.