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David Bennett to Genome-Wide Association Study

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This is a "connection" page, showing publications David Bennett has written about Genome-Wide Association Study.
David Bennett
Connection Strength
7.001
Genome-Wide Association Study
  1. Dissecting the human leptomeninges at single-cell resolution. Nat Commun. 2023 11 03; 14(1):7036.
    View in: PubMed
    Score: 0.201
  2. The power of genetic diversity in genome-wide association studies of lipids. Nature. 2021 12; 600(7890):675-679.
    View in: PubMed
    Score: 0.176
  3. Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants. PLoS Genet. 2021 11; 17(11):e1009918.
    View in: PubMed
    Score: 0.176
  4. Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nat Neurosci. 2021 06; 24(6):810-817.
    View in: PubMed
    Score: 0.168
  5. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nat Genet. 2021 03; 53(3):294-303.
    View in: PubMed
    Score: 0.167
  6. Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021 01 28; 12(1):654.
    View in: PubMed
    Score: 0.166
  7. Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218. Transl Psychiatry. 2020 08 24; 10(1):297.
    View in: PubMed
    Score: 0.161
  8. Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Neurobiol Aging. 2020 09; 93:61-68.
    View in: PubMed
    Score: 0.158
  9. Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults. Transl Psychiatry. 2019 10 03; 9(1):241.
    View in: PubMed
    Score: 0.151
  10. Sex differences in the genetic predictors of Alzheimer's pathology. Brain. 2019 09 01; 142(9):2581-2589.
    View in: PubMed
    Score: 0.151
  11. Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med. 2018 04; 80(3):242-251.
    View in: PubMed
    Score: 0.136
  12. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 07 19; 8(1):80.
    View in: PubMed
    Score: 0.130
  13. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
    View in: PubMed
    Score: 0.126
  14. Differential transcriptome expression in human nucleus accumbens as a function of loneliness. Mol Psychiatry. 2017 07; 22(7):1069-1078.
    View in: PubMed
    Score: 0.124
  15. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582.
    View in: PubMed
    Score: 0.123
  16. Relation of genomic variants for Alzheimer disease dementia to common neuropathologies. Neurology. 2016 Aug 02; 87(5):489-96.
    View in: PubMed
    Score: 0.121
  17. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 2016 05 26; 533(7604):539-42.
    View in: PubMed
    Score: 0.120
  18. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet. 2016 06; 48(6):624-33.
    View in: PubMed
    Score: 0.119
  19. Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology. Alzheimers Dement. 2016 09; 12(9):942-951.
    View in: PubMed
    Score: 0.119
  20. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378.
    View in: PubMed
    Score: 0.115
  21. Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies. Int J Biochem Cell Biol. 2015 Oct; 67:58-64.
    View in: PubMed
    Score: 0.112
  22. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.
    View in: PubMed
    Score: 0.108
  23. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet. 2014 Sep; 10(9):e1004606.
    View in: PubMed
    Score: 0.107
  24. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci. 2014 Sep; 17(9):1156-63.
    View in: PubMed
    Score: 0.106
  25. Epigenomics of Alzheimer's disease. Transl Res. 2015 Jan; 165(1):200-20.
    View in: PubMed
    Score: 0.104
  26. Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol. 2014 Apr; 71(4):429-35.
    View in: PubMed
    Score: 0.103
  27. Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease. Biochem Pharmacol. 2014 Apr 15; 88(4):617-30.
    View in: PubMed
    Score: 0.102
  28. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8.
    View in: PubMed
    Score: 0.100
  29. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7.
    View in: PubMed
    Score: 0.099
  30. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013 Jun 21; 340(6139):1467-71.
    View in: PubMed
    Score: 0.098
  31. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013 Apr 10; 309(14):1483-92.
    View in: PubMed
    Score: 0.097
  32. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68.
    View in: PubMed
    Score: 0.097
  33. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell. 2013 Jan 31; 152(3):642-54.
    View in: PubMed
    Score: 0.095
  34. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78.
    View in: PubMed
    Score: 0.095
  35. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15.
    View in: PubMed
    Score: 0.088
  36. Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet. 2011 Feb; 7(2):e1001308.
    View in: PubMed
    Score: 0.083
  37. Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiol Aging. 2011 Dec; 32(12):2113-22.
    View in: PubMed
    Score: 0.079
  38. Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities. Neurobiol Dis. 2022 Nov; 174:105880.
    View in: PubMed
    Score: 0.047
  39. Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease. Hum Mol Genet. 2022 09 29; 31(19):3355-3366.
    View in: PubMed
    Score: 0.047
  40. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain. 2022 07 29; 145(7):2541-2554.
    View in: PubMed
    Score: 0.046
  41. Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts. Nutrients. 2022 Jul 03; 14(13).
    View in: PubMed
    Score: 0.046
  42. Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease. Alzheimers Dement. 2022 11; 18(11):2042-2054.
    View in: PubMed
    Score: 0.045
  43. Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease. Biol Psychiatry. 2022 07 01; 92(1):25-33.
    View in: PubMed
    Score: 0.044
  44. Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance. Alzheimers Dement. 2022 10; 18(10):1797-1811.
    View in: PubMed
    Score: 0.044
  45. Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Hum Genet. 2022 Jan; 141(1):127-146.
    View in: PubMed
    Score: 0.044
  46. A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease. Nat Commun. 2021 07 22; 12(1):4472.
    View in: PubMed
    Score: 0.043
  47. A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nat Commun. 2021 06 10; 12(1):3517.
    View in: PubMed
    Score: 0.043
  48. Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia. PLoS Genet. 2021 04; 17(4):e1009482.
    View in: PubMed
    Score: 0.042
  49. Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction. Alzheimers Res Ther. 2021 03 04; 13(1):55.
    View in: PubMed
    Score: 0.042
  50. Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. Transl Psychiatry. 2021 02 26; 11(1):146.
    View in: PubMed
    Score: 0.042
  51. Genetic control of the human brain proteome. Am J Hum Genet. 2021 03 04; 108(3):400-410.
    View in: PubMed
    Score: 0.042
  52. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nat Genet. 2021 02; 53(2):143-146.
    View in: PubMed
    Score: 0.042
  53. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 01 01; 78(1):102-113.
    View in: PubMed
    Score: 0.041
  54. Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020 12 08; 11(1):6285.
    View in: PubMed
    Score: 0.041
  55. Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics. Am J Hum Genet. 2020 10 01; 107(4):714-726.
    View in: PubMed
    Score: 0.041
  56. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Rep. 2020 09 01; 32(9):108091.
    View in: PubMed
    Score: 0.040
  57. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain. 2020 08 01; 143(8):2561-2575.
    View in: PubMed
    Score: 0.040
  58. Sex-dependent autosomal effects on clinical progression of Alzheimer's disease. Brain. 2020 07 01; 143(7):2272-2280.
    View in: PubMed
    Score: 0.040
  59. Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways. Alzheimers Dement. 2020 08; 16(8):1134-1145.
    View in: PubMed
    Score: 0.040
  60. A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Commun Biol. 2019; 2:285.
    View in: PubMed
    Score: 0.037
  61. TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits. Am J Hum Genet. 2019 08 01; 105(2):258-266.
    View in: PubMed
    Score: 0.037
  62. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. 2019 08; 18(4):e12964.
    View in: PubMed
    Score: 0.037
  63. Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis. Hum Mol Genet. 2019 03 01; 28(5):718-735.
    View in: PubMed
    Score: 0.036
  64. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.
    View in: PubMed
    Score: 0.036
  65. Disentangling the genetics of lean mass. Am J Clin Nutr. 2019 02 01; 109(2):276-287.
    View in: PubMed
    Score: 0.036
  66. Neuropathological correlates and genetic architecture of microglial activation in elderly human brain. Nat Commun. 2019 01 24; 10(1):409.
    View in: PubMed
    Score: 0.036
  67. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 02; 137(2):209-226.
    View in: PubMed
    Score: 0.036
  68. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nat Genet. 2018 11; 50(11):1584-1592.
    View in: PubMed
    Score: 0.035
  69. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 09 26; 9(1):3945.
    View in: PubMed
    Score: 0.035
  70. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872.
    View in: PubMed
    Score: 0.035
  71. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology. Alzheimers Dement. 2018 12; 14(12):1580-1588.
    View in: PubMed
    Score: 0.034
  72. A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease. Genetics. 2018 05; 209(1):51-64.
    View in: PubMed
    Score: 0.034
  73. A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. Sci Transl Med. 2017 Dec 20; 9(421).
    View in: PubMed
    Score: 0.033
  74. An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome. Nat Neurosci. 2017 Oct; 20(10):1418-1426.
    View in: PubMed
    Score: 0.033
  75. Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. PLoS Med. 2017 04; 14(4):e1002287.
    View in: PubMed
    Score: 0.032
  76. Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2018 06; 23(6):1521-1529.
    View in: PubMed
    Score: 0.032
  77. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 01 18; 8:13624.
    View in: PubMed
    Score: 0.031
  78. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 01 10; 9(1):209-246.
    View in: PubMed
    Score: 0.031
  79. An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biol Psychiatry. 2017 09 01; 82(5):322-329.
    View in: PubMed
    Score: 0.031
  80. Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. Mol Neurobiol. 2017 Dec; 54(10):8021-8032.
    View in: PubMed
    Score: 0.031
  81. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2017 02; 13(2):119-129.
    View in: PubMed
    Score: 0.031
  82. Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nat Neurosci. 2016 11; 19(11):1442-1453.
    View in: PubMed
    Score: 0.031
  83. The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism. Acta Neuropathol. 2016 10; 132(4):503-14.
    View in: PubMed
    Score: 0.031
  84. Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease. Mol Psychiatry. 2017 02; 22(2):287-295.
    View in: PubMed
    Score: 0.030
  85. Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med. 2016 06; 46(8):1613-23.
    View in: PubMed
    Score: 0.030
  86. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nat Commun. 2016 Feb 01; 7:10495.
    View in: PubMed
    Score: 0.029
  87. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23.
    View in: PubMed
    Score: 0.029
  88. Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. Medicine (Baltimore). 2015 Nov; 94(47):e1892.
    View in: PubMed
    Score: 0.029
  89. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2016 Feb; 21(2):189-197.
    View in: PubMed
    Score: 0.028
  90. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Mol Psychiatry. 2015 Feb; 20(2):183-92.
    View in: PubMed
    Score: 0.027
  91. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
    View in: PubMed
    Score: 0.027
  92. FASTKD2 is associated with memory and hippocampal structure in older adults. Mol Psychiatry. 2015 Oct; 20(10):1197-204.
    View in: PubMed
    Score: 0.027
  93. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.
    View in: PubMed
    Score: 0.027
  94. Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans. Alzheimers Dement. 2014 Nov; 10(6):609-618.e11.
    View in: PubMed
    Score: 0.027
  95. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nat Neurosci. 2014 Sep; 17(9):1164-70.
    View in: PubMed
    Score: 0.027
  96. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol. 2014; 127(6):825-43.
    View in: PubMed
    Score: 0.026
  97. Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis. 2013; 36(3):181-188.
    View in: PubMed
    Score: 0.025
  98. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013 Aug 22; 500(7463):477-81.
    View in: PubMed
    Score: 0.025
  99. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52.
    View in: PubMed
    Score: 0.024
  100. Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory. Neurology. 2012 May 08; 78(19):1464-71.
    View in: PubMed
    Score: 0.023
  101. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51.
    View in: PubMed
    Score: 0.023
  102. Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. Am J Hum Genet. 2012 Apr 06; 90(4):720-6.
    View in: PubMed
    Score: 0.023
  103. A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline. Hum Mol Genet. 2012 May 15; 21(10):2377-88.
    View in: PubMed
    Score: 0.022
  104. Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology. 2012 Jan 31; 78(5):334-41.
    View in: PubMed
    Score: 0.022
  105. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov; 32(11):2109.e15-28.
    View in: PubMed
    Score: 0.021
  106. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
    View in: PubMed
    Score: 0.021
  107. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84.
    View in: PubMed
    Score: 0.020
  108. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One. 2010 Jun 21; 5(6):e11244.
    View in: PubMed
    Score: 0.020
  109. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301.
    View in: PubMed
    Score: 0.020
  110. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet. 2010 Mar; 42(3):234-9.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.