D006497Chemicals & DrugsD09.698.373.425450.998953Heparitin SulfateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonPathologyPaoloGattusoPaolo Gattuso349288Gattuso, PaoloProfessorRobertLevenRobert Leven349392Leven, RobertAssociate ProfessorRachelMillerRachel Miller349450Miller, RachelAssociate ProfessorAnnaPlaasAnna Plaas41.87352120000000-87.66713820000000349608Plaas, AnnaProfessor5Associate Professor4Professor15983219Maxhimer JB, Somenek M, Rao G, Pesce CE, Baldwin D, Gattuso P, Schwartz MM, Lewis EJ, Prinz RA, Xu XDiabetesHeparanase-1 gene expression and regulation by high glucose in renal epithelial cells: a potential role in the pathogenesis of proteinuria in diabetic patients. Diabetes. 2005 Jul; 54(7):2172-8.Diabetes2005-07-01T00:00:002005Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: a potential role in the pathogenesis of proteinuria in diabetic patients.14701864Gao G, Plaas A, Thompson VP, Jin S, Zuo F, Sandy JDThe Journal of biological chemistryADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J Biol Chem. 2004 Mar 12; 279(11):10042-51.J Biol Chem2003-12-29T00:00:002003ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.20722014Miller RE, Grodzinsky AJ, Cummings K, Plaas AH, Cole AA, Lee RT, Patwari PArthritis and rheumatismIntraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. Arthritis Rheum. 2010 Dec; 62(12):3686-94.Arthritis Rheum2010-12-01T00:00:002010Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate.0.09918390.007205744research area of0.2457660.02885324subject area forAnatomy and Cell BiologyRush University, Rush Medical Collegetrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorInternal Medicine, Division of Rheumatology8425575Hunt P, Hokom MM, Wiemann B, Leven RM, Arakawa TExperimental hematologyMegakaryocyte proplatelet-like process formation in vitro is inhibited by serum prothrombin, a process which is blocked by matrix-bound glycosaminoglycans. Exp Hematol. 1993 Feb; 21(2):372-81.Exp Hematol1993-02-01T00:00:001993Megakaryocyte proplatelet-like process formation in vitro is inhibited by serum prothrombin, a process which is blocked by matrix-bound glycosaminoglycans.true1Associate ProfessorAssociate Professor