D007375Chemicals & DrugsD12.644.276.374.465.010D12.644.276.374.500.400D12.776.467.374.465.010D12.776.467.374.500.400D23.529.374.465.131D23.529.374.500.40032780.974964Interleukin-1Faculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31068441Li T, Chubinskaya S, Esposito A, Jin X, Tagliafierro L, Loeser R, Hakimiyan AA, Longobardi L, Ozkan H, Spagnoli AScience translational medicineTGF-? type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. Sci Transl Med. 2019 05 08; 11(491).Sci Transl Med2019-05-08T00:00:002019TGF-? type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.KalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessortrue1ProfessorProfessorHowardAnHoward An41.87352120000000-87.66713820000000349055An, HowardProfessortrue1ProfessorProfessortrue1ProfessorProfessorPediatricsSusanaChubinskayaSusanna Chubinskaya349101Chubinskaya, SusanaProfessorAnnaSpagnoliAnna Spagnoli41.87386750000000-87.67102690000000349109Spagnoli, AnnaProfessorPaulCarveyPaul Carvey41.87432800000000-87.67059170000000349203Carvey, PaulProfessor4Professor23460134Kim JS, Ellman MB, Yan D, An HS, Kc R, Li X, Chen D, Xiao G, Cs-Szabo G, Hoskin DW, Buechter DD, Van Wijnen AJ, Im HJJournal of cellular physiologyLactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc. J Cell Physiol. 2013 Sep; 228(9):1884-96.J Cell Physiol2013-09-01T00:00:002013Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc.25311550Gu SX, Li X, Hamilton JL, Chee A, Kc R, Chen D, An HS, Kim JS, Oh CD, Ma YZ, van Wijnen AJ, Im HJGeneMicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc. Gene. 2015 Jan 25; 555(2):80-7.Gene2014-10-12T00:00:002014MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc.0.7977270.016348132research area of0.7123930.03003269subject area for17174540Wilson CG, Palmer AW, Zuo F, Eugui E, Wilson S, Mackenzie R, Sandy JD, Levenston MEMatrix biology : journal of the International Society for Matrix BiologySelective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties. Matrix Biol. 2007 May; 26(4):259-68.Matrix Biol2006-11-11T00:00:002006Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties.Neurological SciencesOrthopedic SurgeryRush University, Rush Medical Collegetrue1ProfessorProfessortrue1ProfessorProfessorPhysiology and Biophysics28970361Nomura A, Gupta VK, Dauer P, Sharma NS, Dudeja V, Merchant N, Saluja AK, Banerjee SMolecular cancer research : MCRNF?B-Mediated Invasiveness in CD133+ Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling. Mol Cancer Res. 2018 01; 16(1):162-172.Mol Cancer Res2017-09-28T00:00:002017NF?B-Mediated Invasiveness in CD133+ Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling.