D009574Chemicals & DrugsD02.640490.997852Nitro CompoundsFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersontrue1ProfessorProfessor17336076Ramaswamy S, McBride JL, Herzog CD, Brandon E, Gasmi M, Bartus RT, Kordower JHNeurobiology of diseaseNeurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease. Neurobiol Dis. 2007 May; 26(2):375-84.Neurobiol Dis2007-01-25T00:00:002007Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease.12781994McBride JL, During MJ, Wuu J, Chen EY, Leurgans SE, Kordower JHExperimental neurologyStructural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF. Exp Neurol. 2003 Jun; 181(2):213-23.Exp Neurol2003-06-01T00:00:002003Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.12746870Hanbury R, Ling ZD, Wuu J, Kordower JHThe Journal of comparative neurologyGFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults. J Comp Neurol. 2003 Jun 30; 461(3):307-16.J Comp Neurol2003-06-30T00:00:002003GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.17712222Ramaswamy S, McBride JL, Kordower JHILAR journalAnimal models of Huntington's disease. ILAR J. 2007; 48(4):356-73.ILAR J2007-01-01T00:00:002007Animal models of Huntington's disease.SueLeurgansSue E Leurgans349391Leurgans, SueProfessorChristopherGoetzChristopher Goetz349622Goetz, ChristopherProfessor4Professor0.3818680.01189034research area of0.0868380.04766378subject area forNeurological SciencesRush University, Rush Medical CollegeDavidBennettDavid A. Bennett41.87328300000000-87.66936330000000349004Bennett, DavidProfessorJeffreyKordowerJeffrey Kordower41.87386750000000-87.67102690000000349008Kordower, JeffreyProfessor19109907O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, H?bert SS, De Strooper B, Haass C, Bennett DA, Vassar RNeuronPhosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26; 60(6):988-1009.Neuron2008-12-26T00:00:002008Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor