25482935Duan L, Perez RE, Hansen M, Gitelis S, Maki CGCancer biology & therapyAntineoplastic Agents; Cisplatin; Drug Resistance, Neoplasm; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-aktApoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Cyclin-Dependent Kinase Inhibitor p27; DNA Damage; Enzyme Activation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterocyclic Compounds, 3-Ring; Humans; Phosphorylation; RNA Interference; RNA, Small Interfering; Tumor Suppressor Protein p53Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1. Cancer Biol Ther. 2014; 15(12):1600-12.Cancer Biol Ther2014-01-01T00:00:002014Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.Faculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD047428Chemicals & Drugs31480.963145Protein Kinase InhibitorsD004249Disorders18300.987247DNA DamageD059447Physiology570.995431Cell Cycle CheckpointsD034622PhenomenaPhysiology22330.986521RNA InterferenceD002945Chemicals & Drugs23910.95537CisplatinD000970Chemicals & Drugs722180.848686Antineoplastic AgentsD011494Chemicals & Drugs12130.991094Protein KinasesD015972Physiology451000.94638Gene Expression Regulation, NeoplasticD019008Physiology30750.934638Drug Resistance, Neoplasmtrue1ProfessorProfessorStevenGitelisSteven Gitelis41.87352120000000-87.66713820000000349068Gitelis, StevenProfessorLeiDuanLei Duan349250Duan, LeiAssistant ProfessorCarlMakiCarl Maki349531Maki, CarlProfessorAuthorship 1012416Assistant Professor4ProfessorAuthorship 598540.4917660.1229413authors10.2521has subject areaD050760Chemicals & Drugs470.992677Cyclin-Dependent Kinase Inhibitor p27D055785Procedures27410.984358Gene Knockdown TechniquesD045744Anatomy812640.921505Cell Line, TumorAuthorship 106415D051057Chemicals & Drugs28560.945164Proto-Oncogene Proteins c-aktD004789Physiology511140.963777Enzyme ActivationD010766Phenomena641720.955488PhosphorylationOrthopedic SurgeryAnatomy and Cell BiologyRush University, Rush Medical CollegeD017209Physiology912520.885081Apoptosistrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessorD034741Chemicals & Drugs33650.972885RNA, Small InterferingD006575Chemicals & Drugs10150.993408Heterocyclic Compounds, 3-RingD006801Living Beings644293510.211905HumansD000071877350.996861Checkpoint Kinase 1D016159Chemicals & Drugs25890.913971Tumor Suppressor Protein p53