PhDGiedriusKanaporisGiedrius Kanaporis41.87432800000000-87.67059170000000349614Kanaporis, GiedriusMy Scopus ID is 21742760800.
My NIH COMMONS name is GKANAPORIS.
Research Areas:
Cardiac electrophysiology, cardiac arrhythmias, heart failure, intracellular calcium signaling in subcellular domains, cell-to-cell coupling.
My Faculty Profile at Rush University Medical Center:
https://www.rushu.rush.edu/faculty/giedrius-kanaporis-phd
My Laboratory:
https://www.rushu.rush.edu/research/departmental-research/physiology-and-biophysics-research/laboratory-lothar-blatter-md-dr-med
My NCBI Bibliography:
https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/48071495/?sort=date&direction=descending
My Scopus:
https://www.scopus.com/authid/detail.uri?authorId=21742760800
Education:
PhD, Kaunas University of Medicine, Kaunas, Lithuania
MS, Vytautas Magnus University, Kaunas, Lithuania
BS, Vytautas Magnus University, Kaunas, LithuaniaAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifierbibo:suffixNamename suffixAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 33903130412286Kanaporis G, Kalik ZM, Blatter LAThe Journal of physiologyAction potential shortening rescues atrial calcium alternans. J Physiol. 2019 02; 597(3):723-740.J Physiol2018-12-05T00:00:002018Action potential shortening rescues atrial calcium alternans.Authorship 35205230917498Treinys R, Kanaporis G, Fischmeister R, Jurevicius JInternational journal of molecular sciencesMetabolic Inhibition Induces Transient Increase of L-type Ca2+ Current in Human and Rat Cardiac Myocytes. Int J Mol Sci. 2019 Mar 26; 20(6).Int J Mol Sci2019-03-26T00:00:002019Metabolic Inhibition Induces Transient Increase of L-type Ca2+ Current in Human and Rat Cardiac Myocytes.D000200Physiology371440.908662Action PotentialsD032383Anatomy181980.818526Myocytes, CardiacD002118Chemicals & Drugs644990.72668CalciumD020013Physiology191780.833586Calcium Signaling8InstructorPaulCarveyPaul Carvey41.87432800000000-87.67059170000000349203Carvey, PaulProfessor1750 West Harrison StChicago60612ILGuozhiXiaoGuozhi Xiao349546Xiao, GuozhiProfessorLotharBlatterLothar Blatter41.87432800000000-87.67059170000000349611Blatter, LotharProfessorMichaelFillMichael Fill41.87432800000000-87.67059170000000349613Fill, MichaelProfessor1125selected publications4.202980.00614656150research areas6.770860.1871422coauthor of228.5872.3816460similar toEduardoRiosEduardo Rios41.87432800000000-87.67059170000000349616Rios, EduardoProfessorTomShannonTom Shannon41.87432800000000-87.67059170000000349656Shannon, TomAssociate ProfessorJohnTangJohn Tang41.87432800000000-87.67059170000000349692Tang, John0000-0003-0104-8324Assistant ProfessorAuthorship 38343931980627Zhu K, Lai Y, Cao H, Bai X, Liu C, Yan Q, Ma L, Chen D, Kanaporis G, Wang J, Li L, Cheng T, Wang Y, Wu C, Xiao GNature communicationsKindlin-2 modulates MafA and ?-catenin expression to regulate ?-cell function and mass in mice. Nat Commun. 2020 01 24; 11(1):484.Nat Commun2020-01-24T00:00:002020Kindlin-2 modulates MafA and ?-catenin expression to regulate ?-cell function and mass in mice.6Assistant Professor5Associate Professor4Professortrue1ProfessorProfessorAuthorship 39798932433891Gussak G, Marszalec W, Yoo S, Modi R, O'Callaghan C, Aistrup GL, Cordeiro JM, Goodrow R, Kanaporis G, Blatter LA, Shiferaw Y, Arora R, Zhou J, Burrell AR, Wasserstrom JACirculation. Arrhythmia and electrophysiologyTriggered Ca2+ Waves Induce Depolarization of Maximum Diastolic Potential and Action Potential Prolongation in Dog Atrial Myocytes. Circ Arrhythm Electrophysiol. 2020 06; 13(6):e008179.Circ Arrhythm Electrophysiol2020-05-20T00:00:002020Triggered Ca2+ Waves Induce Depolarization of Maximum Diastolic Potential and Action Potential Prolongation in Dog Atrial Myocytes.Authorship 107932Authorship 108681Authorship 108861Authorship 110052Authorship 123566Authorship 124451Authorship 133881D006325Anatomy19820.936453Heart AtriaAuthorship 156396Authorship 184174Authorship 188321Authorship 192651Authorship 19731415947524Zablockaite D, Gendviliene V, Macianskiene R, Skeberdis VA, Jurevicius J, Kanaporis G, Gurskaite H, Benetis RMedicina (Kaunas, Lithuania)Effect of hyperosmolarity on beta2-adrenergic stimulation in human atrium. Medicina (Kaunas). 2005; 41(5):401-8.Medicina (Kaunas)2005-01-01T00:00:002005Effect of hyperosmolarity on beta2-adrenergic stimulation in human atrium.16358976Zablockaite D, Gendviliene V, Macianskiene R, Skeberdis VA, Jurevicius J, Kanaporis G, Benetis RRoczniki Akademii Medycznej w Bialymstoku (1995)Changes of beta2-adrenergic stimulation induced by hyperosmosis in human atrium. Rocz Akad Med Bialymst. 2005; 50:244-6.Rocz Akad Med Bialymst2005-01-01T00:00:002005Changes of beta2-adrenergic stimulation induced by hyperosmosis in human atrium.17615163Yum SW, Zhang J, Valiunas V, Kanaporis G, Brink PR, White TW, Scherer SSAmerican journal of physiology. Cell physiologyHuman connexin26 and connexin30 form functional heteromeric and heterotypic channels. Am J Physiol Cell Physiol. 2007 Sep; 293(3):C1032-48.Am J Physiol Cell Physiol2007-07-05T00:00:002007Human connexin26 and connexin30 form functional heteromeric and heterotypic channels.18326694Thomas BC, Minogue PJ, Valiunas V, Kanaporis G, Brink PR, Berthoud VM, Beyer ECInvestigative ophthalmology & visual scienceCataracts are caused by alterations of a critical N-terminal positive charge in connexin50. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2549-56.Invest Ophthalmol Vis Sci2008-03-07T00:00:002008Cataracts are caused by alterations of a critical N-terminal positive charge in connexin50.18378798Kanaporis G, Mese G, Valiuniene L, White TW, Brink PR, Valiunas VThe Journal of general physiologyGap junction channels exhibit connexin-specific permeability to cyclic nucleotides. J Gen Physiol. 2008 Apr; 131(4):293-305.J Gen Physiol2008-04-01T00:00:002008Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides.19736302Valiunas V, Kanaporis G, Valiuniene L, Gordon C, Wang HZ, Li L, Robinson RB, Rosen MR, Cohen IS, Brink PRThe Journal of physiologyCoupling an HCN2-expressing cell to a myocyte creates a two-cell pacing unit. J Physiol. 2009 Nov 01; 587(Pt 21):5211-26.J Physiol2009-09-07T00:00:002009Coupling an HCN2-expressing cell to a myocyte creates a two-cell pacing unit.21148413Kanaporis G, Brink PR, Valiunas VAmerican journal of physiology. Cell physiologyGap junction permeability: selectivity for anionic and cationic probes. Am J Physiol Cell Physiol. 2011 Mar; 300(3):C600-9.Am J Physiol Cell Physiol2010-12-09T00:00:002010Gap junction permeability: selectivity for anionic and cationic probes.21834666Magome N, Kanaporis G, Moisan N, Tanaka K, Agladze KTissue engineering. Part APhoto-control of excitation waves in cardiomyocyte tissue culture. Tissue Eng Part A. 2011 Nov; 17(21-22):2703-11.Tissue Eng Part A2011-08-11T00:00:002011Photo-control of excitation waves in cardiomyocyte tissue culture.23085908Kanaporis G, Marti?iene I, Jurevicius J, Vosyliute R, Navalinskas A, Treinys R, Matiukas A, Pertsov AMJournal of biomedical opticsOptical mapping at increased illumination intensities. J Biomed Opt. 2012 Sep; 17(9):96007-1.J Biomed Opt2012-09-01T00:00:002012Optical mapping at increased illumination intensities.25532796Kanaporis G, Blatter LACirculation researchThe mechanisms of calcium cycling and action potential dynamics in cardiac alternans. Circ Res. 2015 Feb 27; 116(5):846-56.Circ Res2014-12-22T00:00:002014The mechanisms of calcium cycling and action potential dynamics in cardiac alternans.26662365Kanaporis G, Blatter LAThe Journal of physiologyCalcium-activated chloride current determines action potential morphology during calcium alternans in atrial myocytes. J Physiol. 2016 Feb 01; 594(3):699-714.J Physiol2016-01-15T00:00:002016Calcium-activated chloride current determines action potential morphology during calcium alternans in atrial myocytes.27356267Kanaporis G, Blatter LAChannels (Austin, Tex.)Ca(2+)-activated chloride channel activity during Ca(2+) alternans in ventricular myocytes. Channels (Austin). 2016 Nov; 10(6):507-17.Channels (Austin)2016-06-29T00:00:002016Ca(2+)-activated chloride channel activity during Ca(2+) alternans in ventricular myocytes.Authorship 40984233398498Blatter LA, Kanaporis G, Martinez-Hernandez E, Oropeza-Almazan Y, Banach KPflugers Archiv : European journal of physiologyExcitation-contraction coupling and calcium release in atrial muscle. Pflugers Arch. 2021 03; 473(3):317-329.Pflugers Arch2021-01-05T00:00:002021Excitation-contraction coupling and calcium release in atrial muscle.Orthopedic SurgeryRush University, Rush Medical Collegetrue1Assistant ProfessorAssistant ProfessorAuthorship 440843Authorship 44570235274829Martinez-Hernandez E, Blatter LA, Kanaporis GPhysiological reportsL-type Ca2+ channel recovery from inactivation in rabbit atrial myocytes. Physiol Rep. 2022 03; 10(5):e15222.Physiol Rep2022-03-01T00:00:002022L-type Ca2+ channel recovery from inactivation in rabbit atrial myocytes.35501948Martinez-Hernandez E, Kanaporis G, Blatter LAChannels (Austin, Tex.)Mechanism of carvedilol induced action potential and calcium alternans. Channels (Austin). 2022 12; 16(1):97-112.Channels (Austin)2022-12-01T00:00:002022Mechanism of carvedilol induced action potential and calcium alternans.CarolinaFigueroaCarolina Figueroa41.87432800000000-87.67059170000000349855Figueroa, CarolinaAssistant ProfessorAuthorship 26659128257761Kanaporis G, Blatter LAJournal of molecular and cellular cardiologyMembrane potential determines calcium alternans through modulation of SR Ca2+ load and L-type Ca2+ current. J Mol Cell Cardiol. 2017 04; 105:49-58.J Mol Cell Cardiol2017-02-28T00:00:002017Membrane potential determines calcium alternans through modulation of SR Ca2+ load and L-type Ca2+ current.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessorPhysiology and BiophysicsXunAiXun Ai41.87432800000000-87.67059170000000350000Ai, XunProfessorAuthorship 283981Authorship 285881Authorship 28860128666575Kanaporis G, Blatter LAMedicina (Kaunas, Lithuania)Alternans in atria: Mechanisms and clinical relevance. Medicina (Kaunas). 2017; 53(3):139-149.Medicina (Kaunas)2017-06-07T00:00:002017Alternans in atria: Mechanisms and clinical relevance.28498780Kanaporis G, Blatter LAChannels (Austin, Tex.)AP and Ca2+ alternans: An inseparable couple. Channels (Austin). 2017 09 03; 11(5):368-369.Channels (Austin)2017-05-12T00:00:002017AP and Ca2+ alternans: An inseparable couple.28859158Kanaporis G, Treinys R, Fischmeister R, Jurevicius JPloS oneMetabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis. PLoS One. 2017; 12(8):e0184246.PLoS One2017-08-31T00:00:002017Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis.Authorship 462611Authorship 48409137226365Kanaporis G, Martinez-Hernandez E, Blatter LAPhysiological reportsCalcium- and voltage-driven atrial alternans: Insight from [Ca]i and Vm asynchrony. Physiol Rep. 2023 05; 11(10):e15703.Physiol Rep2023-05-01T00:00:002023Calcium- and voltage-driven atrial alternans: Insight from [Ca]i and Vm asynchrony.36426548Kanaporis G, Blatter LAThe Journal of physiologyActivation of small conductance Ca2+ -activated K+ channels suppresses Ca2+ transient and action potential alternans in ventricular myocytes. J Physiol. 2023 01; 601(1):51-67.J Physiol2022-12-14T00:00:002022Activation of small conductance Ca2+ -activated K+ channels suppresses Ca2+ transient and action potential alternans in ventricular myocytes.https://www.rushu.rush.edu/faculty/john-tang-phdFaculty Profile at RUSH University Medical Centerhttps://www.ncbi.nlm.nih.gov/myncbi/browse/collection/51989419/?sort=date&direction=descendingMy NCBI Bibliographyhttp://orcid.org/0000-0003-0104-8324My ORCIDhttps://www.scopus.com/authid/detail.uri?authorId=7404638670My Scopustrue1InstructorInstructorDanBareDan Bare41.87432800000000-87.67059170000000350046Bare, DanInstructor