Lena Al-Harthi to Humans
This is a "connection" page, showing publications Lena Al-Harthi has written about Humans.
Connection Strength
1.934
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CD4 dim CD8 bright T cells are inversely associated with neuro-inflammatory markers among people with HIV. AIDS. 2024 Jan 01; 38(1):1-7.
Score: 0.048
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An Efficient and Cost-Effective Approach to Generate Functional Human Inducible Pluripotent Stem Cell-Derived Astrocytes. Cells. 2023 09 26; 12(19).
Score: 0.048
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HIV infection of non-classical cells in the brain. Retrovirology. 2023 01 13; 20(1):1.
Score: 0.045
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CD4dim CD8bright T Cells Home to the Brain and Mediate HIV Neuroinvasion. J Virol. 2022 08 10; 96(15):e0080422.
Score: 0.044
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Wnt/?-Catenin Protects Lymphocytes from HIV-Mediated Apoptosis via Induction of Bcl-xL. Viruses. 2022 07 02; 14(7).
Score: 0.044
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Anti-HIV Drugs Cause Mitochondrial Dysfunction in Monocyte-Derived Macrophages. Antimicrob Agents Chemother. 2022 04 19; 66(4):e0194121.
Score: 0.043
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?-catenin regulates HIV latency and modulates HIV reactivation. PLoS Pathog. 2022 03; 18(3):e1010354.
Score: 0.043
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?-Catenin Restricts Zika Virus Internalization by Downregulating Axl. J Virol. 2021 08 10; 95(17):e0070521.
Score: 0.041
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Prevalence and correlates of depressive symptoms among people living with HIV attending tertiary care hospitals in Oman. Pan Afr Med J. 2020; 37:90.
Score: 0.039
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CD32 is enriched on CD4dimCD8bright T cells. PLoS One. 2020; 15(9):e0239157.
Score: 0.039
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Canonical Wnts Mediate CD8+ T Cell Noncytolytic Anti-HIV-1 Activity and Correlate with HIV-1 Clinical Status. J Immunol. 2020 10 15; 205(8):2046-2055.
Score: 0.039
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Negative regulation of IL-8 in human astrocytes depends on ?-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction. Cytokine. 2020 12; 136:155252.
Score: 0.038
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What HIV in the Brain Can Teach Us About SARS-CoV-2 Neurological Complications? AIDS Res Hum Retroviruses. 2021 04; 37(4):255-265.
Score: 0.038
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?-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes. Cell Commun Signal. 2020 06 16; 18(1):93.
Score: 0.038
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HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog. 2020 06; 16(6):e1008381.
Score: 0.038
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Dentine hypersensitivity and dentine exposure in Arab patient populations. J Oral Rehabil. 2020 Apr; 47(4):473-479.
Score: 0.037
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Letter to Editor. J Neuroimmune Pharmacol. 2019 03; 14(1):6.
Score: 0.034
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Astrocytes as an HIV CNS reservoir: highlights and reflections of an NIMH-sponsored symposium. J Neurovirol. 2018 12; 24(6):665-669.
Score: 0.034
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Prevalence, severity and explanatory factors of tooth wear in Arab populations. J Dent. 2019 Jan; 80:69-74.
Score: 0.034
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Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines. Immunology. 2018 02; 153(2):203-213.
Score: 0.032
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Plasma dickkopf-related protein 1, an antagonist of the Wnt pathway, is associated with HIV-associated neurocognitive impairment. AIDS. 2017 06 19; 31(10):1379-1385.
Score: 0.031
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HIV and drug abuse mediate astrocyte senescence in a ?-catenin-dependent manner leading to neuronal toxicity. Aging Cell. 2017 10; 16(5):956-965.
Score: 0.031
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?-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes. J Neuroinflammation. 2016 09 10; 13(1):242.
Score: 0.029
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Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS. Glia. 2015 Mar; 63(3):441-51.
Score: 0.026
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Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium. J Neuroimmune Pharmacol. 2014 Jun; 9(3):269-76.
Score: 0.025
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Porcupine is not required for the production of the majority of Wnts from primary human astrocytes and CD8+ T cells. PLoS One. 2014; 9(3):e92159.
Score: 0.025
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?-Catenin/TCF-4 signaling regulates susceptibility of macrophages and resistance of monocytes to HIV-1 productive infection. Curr HIV Res. 2014; 12(3):164-73.
Score: 0.024
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Epigenetic regulation of HIV-1 latency in astrocytes. J Virol. 2014 Mar; 88(5):3031-8.
Score: 0.024
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Periodontal diseases in an Omani adult population: a preliminary study. J Periodontol. 2014 May; 85(5):e104-10.
Score: 0.024
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The impact of periodontitis on oral health-related quality of life: a review of the evidence from observational studies. Aust Dent J. 2013 Sep; 58(3):274-7; quiz 384.
Score: 0.024
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17?-Estradiol inhibits HIV-1 by inducing a complex formation between ?-catenin and estrogen receptor a on the HIV promoter to suppress HIV transcription. Virology. 2013 Sep 01; 443(2):375-83.
Score: 0.023
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Periodontitis among adult populations in the Arab World. Int Dent J. 2013 Feb; 63(1):7-11.
Score: 0.023
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Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/?-catenin signaling in astrocytes: relevance to HIV neuropathogenesis. J Neurosci. 2012 Nov 14; 32(46):16306-13.
Score: 0.022
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Wnt/?-catenin and its diverse physiological cell signaling pathways in neurodegenerative and neuropsychiatric disorders. J Neuroimmune Pharmacol. 2012 Dec; 7(4):725-30.
Score: 0.022
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Interplay between Wnt/?-catenin signaling and HIV: virologic and biologic consequences in the CNS. J Neuroimmune Pharmacol. 2012 Dec; 7(4):731-9.
Score: 0.022
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Comment on "CD4+ CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection". J Immunol. 2012 Jun 15; 188(12):5809; author reply 5809-10.
Score: 0.022
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Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, ?-catenin, and SMAR1 to repress HIV transcription. J Virol. 2012 Sep; 86(17):9495-503.
Score: 0.022
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Role of ?-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes. J Virol. 2012 Feb; 86(4):1911-21.
Score: 0.021
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Mechanisms of HIV-1 latency post HAART treatment area. Curr HIV Res. 2011 Dec 01; 9(8):552-3.
Score: 0.021
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Methamphetamine and HIV-1 Tat down regulate ?-catenin signaling: implications for methampetamine abuse and HIV-1 co-morbidity. J Neuroimmune Pharmacol. 2011 Dec; 6(4):597-607.
Score: 0.020
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IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. J Immunol. 2011 Jun 15; 186(12):6771-8.
Score: 0.020
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Role of ?-catenin/TCF-4 signaling in HIV replication and pathogenesis: insights to informing novel anti-HIV molecular therapeutics. J Neuroimmune Pharmacol. 2011 Jun; 6(2):247-59.
Score: 0.020
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Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. J Immunol. 2010 Aug 15; 185(4):2013-9.
Score: 0.019
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Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. J Infect Dis. 2010 Mar 15; 201(6):823-34.
Score: 0.019
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Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface. Blood. 2009 Oct 29; 114(18):3841-53.
Score: 0.018
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Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol. 2008 Mar; 82(6):2813-20.
Score: 0.016
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Immunophenotypic alterations in acute and early HIV infection. Clin Immunol. 2007 Dec; 125(3):299-308.
Score: 0.016
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Human immunodeficiency virus-restricted replication in astrocytes and the ability of gamma interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway. J Virol. 2007 Jun; 81(11):5864-71.
Score: 0.015
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HIV infection of primary CD4+ Th2 cells, defined by expression of the chemoattractant receptor-homologous (CRTH2), induces a Th0 phenotype. AIDS Res Hum Retroviruses. 2007 Feb; 23(2):269-77.
Score: 0.015
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Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway. Virology. 2006 Jul 05; 350(2):443-52.
Score: 0.014
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Evaluating the impact of hepatitis C virus (HCV) on highly active antiretroviral therapy-mediated immune responses in HCV/HIV-coinfected women: role of HCV on expression of primed/memory T cells. J Infect Dis. 2006 May 01; 193(9):1202-10.
Score: 0.014
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Gamma interferon primes productive human immunodeficiency virus infection in astrocytes. J Virol. 2006 Jan; 80(1):541-4.
Score: 0.014
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Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration. J Leukoc Biol. 2006 Jan; 79(1):4-6.
Score: 0.014
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Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells. Immunology. 2005 Mar; 114(3):322-35.
Score: 0.013
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Immune modulation of HIV replication: relevance to HIV immuno- and neuro-pathogenesis. Curr HIV Res. 2004 Oct; 2(4):395-401.
Score: 0.013
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Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells. Blood. 2004 Jun 15; 103(12):4581-7.
Score: 0.012
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Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients. HIV Med. 2004 Jan; 5(1):55-65.
Score: 0.012
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The Human Microbiome and Its Role in Musculoskeletal Disorders. Genes (Basel). 2023 10 14; 14(10).
Score: 0.012
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CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV. Blood. 2003 Sep 15; 102(6):2156-64.
Score: 0.012
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An Efficient Humanized Mouse Model for Oral Anti-Retroviral Administration. Cells. 2023 03 28; 12(7).
Score: 0.012
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CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection. Immunology. 2003 Jan; 108(1):3-9.
Score: 0.011
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Bulk IgG glycosylation predicts COVID-19 severity and vaccine antibody response. Cell Rep. 2022 12 13; 41(11):111799.
Score: 0.011
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Immune recovery in HIV disease: role of the thymus and T cell expansion in immune reconstitution strategies. J Hematother Stem Cell Res. 2002 Oct; 11(5):777-86.
Score: 0.011
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Bone Quality in Relation to HIV and Antiretroviral Drugs. Curr HIV/AIDS Rep. 2022 10; 19(5):312-327.
Score: 0.011
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Interleukin-7-treated naive T cells can be productively infected by T-cell-adapted and primary isolates of human immunodeficiency virus 1. Blood. 2002 May 01; 99(9):3310-8.
Score: 0.011
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Immune reconstitution after successful treatment with protease inhibitor-based and protease inhibitor-sparing antiretroviral regimens. J Acquir Immune Defic Syndr. 2002 Apr 15; 29(5):544-5.
Score: 0.011
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Trophoblasts are productively infected by CD4-independent isolate of HIV type 1. AIDS Res Hum Retroviruses. 2002 Jan 01; 18(1):13-7.
Score: 0.011
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Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire. J Proteome Res. 2022 01 07; 21(1):274-288.
Score: 0.011
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T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals. AIDS. 2001 Sep 28; 15(14):1757-64.
Score: 0.010
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A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding. AIDS. 2001 Aug 17; 15(12):1535-43.
Score: 0.010
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Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells. Immunology. 2001 Jul; 103(3):270-80.
Score: 0.010
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HIV in the female genital tract: viral shedding and mucosal immunity. Clin Obstet Gynecol. 2001 Jun; 44(2):144-53.
Score: 0.010
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Change in Circulating Undercarboxylated Osteocalcin (ucOCN) Is Associated With Fat Accumulation in HIV-Seropositive Women. J Acquir Immune Defic Syndr. 2021 04 15; 86(5):e139-e145.
Score: 0.010
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Impact of vitamin D on neurocognitive function in dementia, depression, schizophrenia and ADHD. Front Biosci (Landmark Ed). 2021 Jan 01; 26(3):566-611.
Score: 0.010
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The impact of the ovulatory cycle on cytokine production: evaluation of systemic, cervicovaginal, and salivary compartments. J Interferon Cytokine Res. 2000 Aug; 20(8):719-24.
Score: 0.010
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Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease. AIDS. 2000 May 05; 14(7):761-70.
Score: 0.009
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Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA). J Immunol Methods. 2000 Apr 03; 237(1-2):187-97.
Score: 0.009
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Ginkgolic acid inhibits fusion of enveloped viruses. Sci Rep. 2020 03 16; 10(1):4746.
Score: 0.009
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The far-reaching HAND of cART: cART effects on astrocytes. J Neuroimmune Pharmacol. 2021 03; 16(1):144-158.
Score: 0.009
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Bacterial vaginosis-associated microflora isolated from the female genital tract activates HIV-1 expression. J Acquir Immune Defic Syndr. 1999 Jul 01; 21(3):194-202.
Score: 0.009
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Methamphetamine decreases K+ channel function in human fetal astrocytes by activating the trace amine-associated receptor type-1. J Neurochem. 2019 01; 148(1):29-45.
Score: 0.009
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A human immunodeficiency virus (HIV)-inducing factor from the female genital tract activates HIV-1 gene expression through the kappaB enhancer. J Infect Dis. 1998 Nov; 178(5):1343-51.
Score: 0.008
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Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review). Int J Mol Med. 1998 May; 1(5):875-81.
Score: 0.008
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Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production. J Clin Immunol. 1998 Mar; 18(2):124-31.
Score: 0.008
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Molecular inhibition of HIV type 1 by HIV type 2: effectiveness in peripheral blood mononuclear cells. AIDS Res Hum Retroviruses. 1998 Jan 01; 14(1):59-64.
Score: 0.008
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Inhibition of cytokine-driven human immunodeficiency virus type 1 replication by protease inhibitor. J Infect Dis. 1997 Nov; 176(5):1175-9.
Score: 0.008
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Aging alters voltage-gated calcium channels in prefrontal cortex pyramidal neurons in the HIV brain. J Neurovirol. 2018 02; 24(1):113-118.
Score: 0.008
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The periodontal restorative interface: esthetic considerations. Periodontol 2000. 2017 06; 74(1):74-101.
Score: 0.008
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Chronic periodontitis and implant dentistry. Periodontol 2000. 2017 06; 74(1):63-73.
Score: 0.008
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Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):172-80.
Score: 0.007
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HIV Infection Leads to Redistribution of Leaky Claudin-2 in the Intestine of Humanized SCID IL-2R(-/-) Hu-PBMC Mice. AIDS Res Hum Retroviruses. 2015 Aug; 31(8):774-5.
Score: 0.007
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HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice. AIDS Res Hum Retroviruses. 2014 Jul; 30(7):677-84.
Score: 0.006
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NKG2D signaling on CD8? T cells represses T-bet and rescues CD4-unhelped CD8? T cell memory recall but not effector responses. Nat Med. 2012 Feb 26; 18(3):422-8.
Score: 0.005
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Human FasL gene is a target of ?-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions. PLoS One. 2011; 6(10):e26143.
Score: 0.005
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Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology. 2011 Jun 20; 415(1):56-68.
Score: 0.005
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CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. J Infect Dis. 2008 May 15; 197(10):1402-7.
Score: 0.004
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Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals. Immunology. 2007 Apr; 120(4):526-35.
Score: 0.004
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Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels. J Infect Dis. 2007 Mar 01; 195(5):734-8.
Score: 0.004
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Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women. J Infect Dis. 2007 Jan 01; 195(1):124-33.
Score: 0.004
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Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells. J Immunol. 2006 Jul 15; 177(2):1028-39.
Score: 0.004
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Assessing thymopoiesis in patients with common variable immunodeficiency as measured by T-cell receptor excision circles. Ann Allergy Asthma Immunol. 2004 Nov; 93(5):478-84.
Score: 0.003
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Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection. J Infect Dis. 2003 Dec 15; 188(12):1804-14.
Score: 0.003
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Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr. 2003 Jun 01; 33(2):175-83.
Score: 0.003
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Entrapment of recent thymic emigrants in lymphoid tissues from HIV-infected patients: association with HIV cellular viral load. AIDS. 2002 Nov 08; 16(16):2119-27.
Score: 0.003
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Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and na?ve phenotypes. Clin Immunol. 2000 Nov; 97(2):95-101.
Score: 0.002
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Interleukin-10 enhances tumor necrosis factor-alpha activation of HIV-1 transcription in latently infected T cells. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Dec 01; 19(4):321-31.
Score: 0.002
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The cAMP-dependent protein kinase A and protein kinase C-beta pathways synergistically interact to activate HIV-1 transcription in latently infected cells of monocyte/macrophage lineage. Virology. 1998 Jun 05; 245(2):257-69.
Score: 0.002
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Rationale for immune-based therapies for HIV-1 infection. J Lab Clin Med. 1998 Mar; 131(3):197-206.
Score: 0.002
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TNFalpha cooperates with the protein kinase A pathway to synergistically increase HIV-1 LTR transcription via downstream TRE-like cAMP response elements. Virology. 1997 Oct 27; 237(2):422-9.
Score: 0.002
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A potent activator of HIV-1 replication is present in the genital tract of a subset of HIV-1-infected and uninfected women. AIDS. 1997 Sep; 11(11):1319-26.
Score: 0.002
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Immunological effects of antiretroviral and immune therapies for HIV. AIDS. 1997; 11 Suppl A:S149-55.
Score: 0.002