MD, PhDJosefinaRamos-FrancoJosefina Ramos-Franco41.87432800000000-87.67059170000000349505Ramos-Franco, JosefinaMy Scopus ID is 6505921249.
My NIH COMMONS name is JRAMOS-FRANCO.
Research Areas:
Calcium release mediated by IP3R and RyR channels, mechanisms of local calcium control in cells.
My Faculty Profile at Rush University Medical Center:
https://www.rushu.rush.edu/faculty/josefina-ramos-franco-md-phd
My Laboratory:
https://www.rushu.rush.edu/research/departmental-research/physiology-and-biophysics-research/laboratory-josefina-ramos-franco-md-phd
My NCBI Bibliography:
https://www.ncbi.nlm.nih.gov/pubmed/?term=Ramos-Franco+J
My Scopus:
https://www.scopus.com/authid/detail.uri?authorId=6505921249
Education:
MD, Universidad Autonoma de Puebla, Mexico
PhD, Universidad Nacional Autonoma de MexicoAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifierbibo:suffixNamename suffixAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD004721Anatomy19280.98214Endoplasmic ReticulumAuthorship 36521531333477Aguilar-Sanchez Y, Rodriguez de Yurre A, Argenziano M, Escobar AL, Ramos-Franco JFrontiers in physiologyTransmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level. Front Physiol. 2019; 10:773.Front Physiol2019-07-03T00:00:002019Transmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level.D002118Chemicals & Drugs644990.72668CalciumD020013Physiology191780.833586Calcium SignalingDanielNicholsonDaniel Nicholson349038Nicholson, DanielAssistant ProfessorKalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessortrue1Assistant ProfessorAssistant Professor8InstructorArtemAyuyanArtem G Ayuyan41.87432800000000-87.67059170000000349159Ayuyan, ArtemAssistant ProfessorRichardByrneRichard Byrne349198Byrne, RichardProfessorPaulCarveyPaul Carvey41.87432800000000-87.67059170000000349203Carvey, PaulProfessorVladimirChernyVladimir V Cherny41.87432800000000-87.67059170000000349213Cherny, VladimirAssistant ProfessorDirkGillespieDirk Gillespie41.87432800000000-87.67059170000000349292Gillespie, DirkProfessorD006352Anatomy331800.915804Heart Ventricles1750 West Harrison StChicago60612IL1123selected publications2.438120.0090646129research areas1.880310.04182177coauthor of78.76911.3733260similar toLotharBlatterLothar Blatter41.87432800000000-87.67059170000000349611Blatter, LotharProfessorMichaelFillMichael Fill41.87432800000000-87.67059170000000349613Fill, MichaelProfessorEduardoRiosEduardo Rios41.87432800000000-87.67059170000000349616Rios, EduardoProfessorTomShannonTom Shannon41.87432800000000-87.67059170000000349656Shannon, TomAssociate Professor6Assistant Professor5Associate Professor4ProfessorD019837Chemicals & Drugs161730.872316Ryanodine Receptor Calcium Release ChannelAuthorship 109544Authorship 112402Authorship 117264Authorship 119521Authorship 132446Authorship 132581Authorship 133811Authorship 137971Authorship 143101Authorship 145247Authorship 146782Authorship 149395Authorship 154681Authorship 164556Authorship 192081Authorship 19353315626694P?rez CG, Copello JA, Li Y, Karko KL, G?mez L, Ramos-Franco J, Fill M, Escobar AL, Mej?a-Alvarez RAmerican journal of physiology. Heart and circulatory physiologyRyanodine receptor function in newborn rat heart. Am J Physiol Heart Circ Physiol. 2005 May; 288(5):H2527-40.Am J Physiol Heart Circ Physiol2004-12-30T00:00:002004Ryanodine receptor function in newborn rat heart.16908061Snopko RM, Aromolaran AS, Karko KL, Ramos-Franco J, Blatter LA, Mej?a-Alvarez RCell calciumCell culture modifies Ca2+ signaling during excitation-contraction coupling in neonate cardiac myocytes. Cell Calcium. 2007 Jan; 41(1):13-25.Cell Calcium2006-08-14T00:00:002006Cell culture modifies Ca2+ signaling during excitation-contraction coupling in neonate cardiac myocytes.18468619Snopko RM, Ramos-Franco J, Di Maio A, Karko KL, Manley C, Piedras-Renter?a E, Mej?a-Alvarez RJournal of molecular and cellular cardiologyCa2+ sparks and cellular distribution of ryanodine receptors in developing cardiomyocytes from rat. J Mol Cell Cardiol. 2008 Jun; 44(6):1032-1044.J Mol Cell Cardiol2008-03-29T00:00:002008Ca2+ sparks and cellular distribution of ryanodine receptors in developing cardiomyocytes from rat.18722342Porta M, Diaz-Sylvester PL, Nani A, Ramos-Franco J, Copello JABiochimica et biophysica actaRyanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A. Biochim Biophys Acta. 2008 Nov; 1778(11):2469-79.Biochim Biophys Acta2008-08-03T00:00:002008Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A.19804727Qin J, Valle G, Nani A, Chen H, Ramos-Franco J, Nori A, Volpe P, Fill MBiophysical journalRyanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms. Biophys J. 2009 Oct 07; 97(7):1961-70.Biophys J2009-10-07T00:00:002009Ryanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms.20419313Ramos-Franco J, Gomez AM, Nani A, Liu Y, Copello JA, Fill MPflugers Archiv : European journal of physiologyRyanodol action on calcium sparks in ventricular myocytes. Pflugers Arch. 2010 Sep; 460(4):767-76.Pflugers Arch2010-04-24T00:00:002010Ryanodol action on calcium sparks in ventricular myocytes.21320437Porta M, Zima AV, Nani A, Diaz-Sylvester PL, Copello JA, Ramos-Franco J, Blatter LA, Fill MBiophysical journalSingle ryanodine receptor channel basis of caffeine's action on Ca2+ sparks. Biophys J. 2011 Feb 16; 100(4):931-8.Biophys J2011-02-16T00:00:002011Single ryanodine receptor channel basis of caffeine's action on Ca2+ sparks.22960455Escobar AL, Perez CG, Reyes ME, Lucero SG, Kornyeyev D, Mej?a-Alvarez R, Ramos-Franco JJournal of molecular and cellular cardiologyRole of inositol 1,4,5-trisphosphate in the regulation of ventricular Ca(2+) signaling in intact mouse heart. J Mol Cell Cardiol. 2012 Dec; 53(6):768-79.J Mol Cell Cardiol2012-08-31T00:00:002012Role of inositol 1,4,5-trisphosphate in the regulation of ventricular Ca(2+) signaling in intact mouse heart.26565013Ramos-Franco J, Aguilar-Sanchez Y, Escobar ALCirculation researchIntact Heart Loose Patch Photolysis Reveals Ionic Current Kinetics During Ventricular Action Potentials. Circ Res. 2016 Jan 22; 118(2):203-15.Circ Res2015-11-12T00:00:002015Intact Heart Loose Patch Photolysis Reveals Ionic Current Kinetics During Ventricular Action Potentials.27114611Ramos-Franco J, Fill MThe Journal of general physiologyApproaching ryanodine receptor therapeutics from the calcin angle. J Gen Physiol. 2016 05; 147(5):369-73.J Gen Physiol2016-05-01T00:00:002016Approaching ryanodine receptor therapeutics from the calcin angle.9295347Perez PJ, Ramos-Franco J, Fill M, Mignery GAThe Journal of biological chemistryIdentification and functional reconstitution of the type 2 inositol 1,4,5-trisphosphate receptor from ventricular cardiac myocytes. J Biol Chem. 1997 Sep 19; 272(38):23961-9.J Biol Chem1997-09-19T00:00:001997Identification and functional reconstitution of the type 2 inositol 1,4,5-trisphosphate receptor from ventricular cardiac myocytes.9675184Ramos-Franco J, Fill M, Mignery GABiophysical journalIsoform-specific function of single inositol 1,4,5-trisphosphate receptor channels. Biophys J. 1998 Aug; 75(2):834-9.Biophys J1998-08-01T00:00:001998Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels.9826600Ramos-Franco J, Caenepeel S, Fill M, Mignery GBiophysical journalSingle channel function of recombinant type-1 inositol 1,4,5-trisphosphate receptor ligand binding domain splice variants. Biophys J. 1998 Dec; 75(6):2783-93.Biophys J1998-12-01T00:00:001998Single channel function of recombinant type-1 inositol 1,4,5-trisphosphate receptor ligand binding domain splice variants.10436000Ramos-Franco J, Galvan D, Mignery GA, Fill MThe Journal of general physiologyLocation of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor. J Gen Physiol. 1999 Aug; 114(2):243-50.J Gen Physiol1999-08-01T00:00:001999Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor.10969001Ramos-Franco J, Bare D, Caenepeel S, Nani A, Fill M, Mignery GBiophysical journalSingle-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor. Biophys J. 2000 Sep; 79(3):1388-99.Biophys J2000-09-01T00:00:002000Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor.12695486Ramos J, Jung W, Ramos-Franco J, Mignery GA, Fill MThe Journal of general physiologySingle channel function of inositol 1,4,5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras. J Gen Physiol. 2003 May; 121(5):399-411.J Gen Physiol2003-04-14T00:00:002003Single channel function of inositol 1,4,5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras.Neurological SciencesRush University, Rush Medical CollegeAuthorship 418442334111951Yin L, Zahradnikova A, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqu?s-Sul? E, Aguilar-S?nchez Y, Fern?ndez-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, ?lvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, G?mez AMCirculation researchImpaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52.Circ Res2021-06-11T00:00:002021Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation.Authorship 434311134202968Blancard M, Touat-Hamici Z, Aguilar-Sanchez Y, Yin L, Vaksmann G, Roux-Buisson N, Fressart V, Denjoy I, Klug D, Neyroud N, Ramos-Franco J, Gomez AM, Guicheney PJournal of personalized medicineA Type 2 Ryanodine Receptor Variant in the Helical Domain 2 Associated with an Impairment of the Adrenergic Response. J Pers Med. 2021 Jun 20; 11(6).J Pers Med2021-06-20T00:00:002021A Type 2 Ryanodine Receptor Variant in the Helical Domain 2 Associated with an Impairment of the Adrenergic Response.true1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant ProfessorAuthorship 442621435621185Sun B, Ni M, Tian S, Guo W, Cai S, Sondergaard MT, Chen Y, Mu Y, Estillore JP, Wang R, Chen J, Overgaard MT, Fill M, Ramos-Franco J, Nyegaard M, Wayne Chen SRJournal of cellular physiologyA gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice. J Cell Physiol. 2022 08; 237(8):3305-3316.J Cell Physiol2022-05-27T00:00:002022A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.Neurological SurgeryCarlosMannoCarlos Manno41.87432800000000-87.67059170000000349854Manno, CarlosAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorPhysiology and BiophysicsAuthorship 2725718383014Ramos-Franco J, Lo CF, Breitwieser GECirculation researchPlatelet-activating factor receptor-dependent activation of the muscarinic K+ current in bullfrog atrial myocytes. Circ Res. 1993 Apr; 72(4):786-94.Circ Res1993-04-01T00:00:001993Platelet-activating factor receptor-dependent activation of the muscarinic K+ current in bullfrog atrial myocytes.true1InstructorInstructorJiajieYanJiajie Yan41.87432800000000-87.67059170000000350034Yan, JiajieInstructorAuthorship 46500936881190Tambeaux A, Aguilar-S?nchez Y, Santiago DJ, Mascitti M, DiNovo KM, Mej?a-Alvarez R, Fill M, Wayne Chen SR, Ramos-Franco JPflugers Archiv : European journal of physiologyLigand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation. Pflugers Arch. 2023 05; 475(5):569-581.Pflugers Arch2023-03-07T00:00:002023Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.Authorship 322941929906573Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DANeurobiology of learning and memoryStore depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiol Learn Mem. 2018 10; 154:141-157.Neurobiol Learn Mem2018-06-12T00:00:002018Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.