31939288Lyu H, Petukhov PA, Banta PR, Jadhav A, Lea WA, Cheng Q, Arn?r ESJ, Simeonov A, Thatcher GRJ, Angelucci F, Williams DLACS infectious diseasesEnzyme Inhibitors; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Schistosoma mansoni; Schistosomiasis; SchistosomicidesAnimals; Drug Discovery; High-Throughput Screening Assays; Inhibitory Concentration 50; Mice; NADP; Oxidation-ReductionCharacterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. ACS Infect Dis. 2020 03 13; 6(3):393-405.ACS Infect Dis2020-01-24T00:00:002020Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis.Faculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings32045910.519111AnimalsD009097Chemicals & Drugs5260.979153Multienzyme ComplexesD010084Phenomena28730.978651Oxidation-ReductionD012550Living Beings2420.956093Schistosoma mansoniD004791Chemicals & Drugs681450.945124Enzyme InhibitorsAuthorship 38296110.7485670.7485671authors10.2513has subject areaDavidWilliamsDavid Lee Williams349574Williams, DavidAssociate Professor5Associate ProfessorD051379Living Beings18916170.700511MiceD009247Chemicals & Drugs2200.981362NADH, NADPH OxidoreductasesD020128Concepts & Ideas570.997831Inhibitory Concentration 50D012552Disorders380.989943SchistosomiasisRush University, Rush Medical CollegeD009249Chemicals & Drugs690.996186NADPD012556Chemicals & Drugs1110.984463Schistosomicidestrue1Associate ProfessorAssociate ProfessorMicrobial Pathogens and ImmunityD057166Procedures6100.99227High-Throughput Screening AssaysD055808Procedures16200.980831Drug Discovery