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Thomas DeCoursey to Ion Channels

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This is a "connection" page, showing publications Thomas DeCoursey has written about Ion Channels.
Thomas DeCoursey
Connection Strength
17.170
Ion Channels
  1. Analysis of an electrostatic mechanism for ?pH dependent gating of the voltage-gated proton channel, HV1, supports a contribution of protons to gating charge. Biochim Biophys Acta Bioenerg. 2021 11 01; 1862(11):148480.
    View in: PubMed
    Score: 0.670
  2. Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel. J Gen Physiol. 2020 10 05; 152(10).
    View in: PubMed
    Score: 0.633
  3. Voltage-gated proton channels exist in the plasma membrane of human oocytes. Hum Reprod. 2019 10 02; 34(10):1974-1983.
    View in: PubMed
    Score: 0.590
  4. Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):18951-18961.
    View in: PubMed
    Score: 0.586
  5. Histidine168 is crucial for ?pH-dependent gating of the human voltage-gated proton channel, hHV1. J Gen Physiol. 2018 06 04; 150(6):851-862.
    View in: PubMed
    Score: 0.535
  6. Exotic properties of a voltage-gated proton channel from the snail Helisoma trivolvis. J Gen Physiol. 2018 06 04; 150(6):835-850.
    View in: PubMed
    Score: 0.535
  7. Voltage and pH sensing by the voltage-gated proton channel, HV1. J R Soc Interface. 2018 04; 15(141).
    View in: PubMed
    Score: 0.532
  8. CrossTalk proposal: Proton permeation through HV 1 requires transient protonation of a conserved aspartate in the S1 transmembrane helix. J Physiol. 2017 11 15; 595(22):6793-6795.
    View in: PubMed
    Score: 0.515
  9. The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase. Immunol Rev. 2016 09; 273(1):194-218.
    View in: PubMed
    Score: 0.476
  10. Insights into the structure and function of HV1 from a meta-analysis of mutation studies. J Gen Physiol. 2016 08; 148(2):97-118.
    View in: PubMed
    Score: 0.474
  11. Structural revelations of the human proton channel. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13430-1.
    View in: PubMed
    Score: 0.448
  12. Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1. J Gen Physiol. 2015 Nov; 146(5):343-56.
    View in: PubMed
    Score: 0.448
  13. The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma. Biochemistry. 2015 Jun 02; 54(21):3250-68.
    View in: PubMed
    Score: 0.436
  14. Philosophy of voltage-gated proton channels. J R Soc Interface. 2014 Mar 06; 11(92):20130799.
    View in: PubMed
    Score: 0.395
  15. Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1. J Gen Physiol. 2013 Dec; 142(6):625-40.
    View in: PubMed
    Score: 0.392
  16. Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev. 2013 Apr; 93(2):599-652.
    View in: PubMed
    Score: 0.376
  17. Consequences of dimerization of the voltage-gated proton channel. Prog Mol Biol Transl Sci. 2013; 117:335-60.
    View in: PubMed
    Score: 0.370
  18. Aspartate?112 is the selectivity filter of the human voltage-gated proton channel. Nature. 2011 Oct 23; 480(7376):273-7.
    View in: PubMed
    Score: 0.340
  19. Oligomerization of the voltage-gated proton channel. Channels (Austin). 2010 Jul-Aug; 4(4):260-5.
    View in: PubMed
    Score: 0.312
  20. Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating. J Physiol. 2010 May 01; 588(Pt 9):1435-49.
    View in: PubMed
    Score: 0.304
  21. Voltage-gated proton channels find their dream job managing the respiratory burst in phagocytes. Physiology (Bethesda). 2010 Feb; 25(1):27-40.
    View in: PubMed
    Score: 0.302
  22. Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes. J Biol Chem. 2010 Feb 19; 285(8):5117-21.
    View in: PubMed
    Score: 0.300
  23. Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):18022-7.
    View in: PubMed
    Score: 0.295
  24. The intimate and mysterious relationship between proton channels and NADPH oxidase. FEBS Lett. 2009 Jan 05; 583(1):7-12.
    View in: PubMed
    Score: 0.279
  25. Voltage-gated proton channels: what's next? J Physiol. 2008 Nov 15; 586(22):5305-24.
    View in: PubMed
    Score: 0.275
  26. Voltage-gated proton channels. Cell Mol Life Sci. 2008 Aug; 65(16):2554-73.
    View in: PubMed
    Score: 0.272
  27. Detailed comparison of expressed and native voltage-gated proton channel currents. J Physiol. 2008 May 15; 586(10):2477-86.
    View in: PubMed
    Score: 0.265
  28. Pharmacology of voltage-gated proton channels. Curr Pharm Des. 2007; 13(23):2400-20.
    View in: PubMed
    Score: 0.244
  29. Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol. 2007 Mar 01; 579(Pt 2):327-44.
    View in: PubMed
    Score: 0.243
  30. Voltage-gated proton channels help regulate pHi in rat alveolar epithelium. Am J Physiol Lung Cell Mol Physiol. 2005 Feb; 288(2):L398-408.
    View in: PubMed
    Score: 0.210
  31. During the respiratory burst, do phagocytes need proton channels or potassium channels, or both? Sci STKE. 2004 May 11; 2004(233):pe21.
    View in: PubMed
    Score: 0.203
  32. Interactions between NADPH oxidase and voltage-gated proton channels: why electron transport depends on proton transport. FEBS Lett. 2003 Nov 27; 555(1):57-61.
    View in: PubMed
    Score: 0.197
  33. Diversity of voltage gated proton channels. Front Biosci. 2003 Sep 01; 8:s1266-79.
    View in: PubMed
    Score: 0.193
  34. Properties of single voltage-gated proton channels in human eosinophils estimated by noise analysis and by direct measurement. J Gen Physiol. 2003 Jun; 121(6):615-28.
    View in: PubMed
    Score: 0.190
  35. Voltage-gated proton channels and other proton transfer pathways. Physiol Rev. 2003 Apr; 83(2):475-579.
    View in: PubMed
    Score: 0.188
  36. Interactions between NADPH oxidase-related proton and electron currents in human eosinophils. J Physiol. 2001 Sep 15; 535(Pt 3):767-81.
    View in: PubMed
    Score: 0.169
  37. Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid. J Physiol. 2001 Sep 15; 535(Pt 3):783-94.
    View in: PubMed
    Score: 0.169
  38. Voltage-gated proton channels in microglia. Prog Neurobiol. 2001 Jun; 64(3):277-305.
    View in: PubMed
    Score: 0.166
  39. Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6885-9.
    View in: PubMed
    Score: 0.155
  40. Common themes and problems of bioenergetics and voltage-gated proton channels. Biochim Biophys Acta. 2000 May 12; 1458(1):104-19.
    View in: PubMed
    Score: 0.154
  41. Expression and function of voltage gated proton channels (Hv1) in MDA-MB-231 cells. PLoS One. 2020; 15(5):e0227522.
    View in: PubMed
    Score: 0.154
  42. pH-dependent inhibition of voltage-gated H(+) currents in rat alveolar epithelial cells by Zn(2+) and other divalent cations. J Gen Physiol. 1999 Dec; 114(6):819-38.
    View in: PubMed
    Score: 0.149
  43. Gating currents indicate complex gating of voltage-gated proton channels. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9057-9059.
    View in: PubMed
    Score: 0.137
  44. Rebuttal from Thomas E. DeCoursey. J Physiol. 2017 11 15; 595(22):6801.
    View in: PubMed
    Score: 0.129
  45. Deuterium isotope effects on permeation and gating of proton channels in rat alveolar epithelium. J Gen Physiol. 1997 Apr; 109(4):415-34.
    View in: PubMed
    Score: 0.124
  46. Identification of a vacuolar proton channel that triggers the bioluminescent flash in dinoflagellates. PLoS One. 2017; 12(2):e0171594.
    View in: PubMed
    Score: 0.123
  47. Proton and chloride currents in Chinese hamster ovary cells. Membr Cell Biol. 1997; 11(3):337-47.
    View in: PubMed
    Score: 0.122
  48. Effects of buffer concentration on voltage-gated H+ currents: does diffusion limit the conductance? Biophys J. 1996 Jul; 71(1):182-93.
    View in: PubMed
    Score: 0.118
  49. Ion channels in human THP-1 monocytes. J Membr Biol. 1996 Jul; 152(2):117-30.
    View in: PubMed
    Score: 0.118
  50. Voltage-activated proton currents in human THP-1 monocytes. J Membr Biol. 1996 Jul; 152(2):131-40.
    View in: PubMed
    Score: 0.118
  51. Ion channel expression in PMA-differentiated human THP-1 macrophages. J Membr Biol. 1996 Jul; 152(2):141-57.
    View in: PubMed
    Score: 0.118
  52. Voltage-activated proton currents in membrane patches of rat alveolar epithelial cells. J Physiol. 1995 Dec 01; 489 ( Pt 2):299-307.
    View in: PubMed
    Score: 0.113
  53. The voltage-activated hydrogen ion conductance in rat alveolar epithelial cells is determined by the pH gradient. J Gen Physiol. 1995 Jun; 105(6):861-96.
    View in: PubMed
    Score: 0.109
  54. Selectivity Mechanism of the Voltage-gated Proton Channel, HV1. Sci Rep. 2015 May 08; 5:10320.
    View in: PubMed
    Score: 0.109
  55. Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):18078-83.
    View in: PubMed
    Score: 0.105
  56. Voltage-activated hydrogen ion currents. J Membr Biol. 1994 Sep; 141(3):203-23.
    View in: PubMed
    Score: 0.104
  57. Analysis of electrophysiological properties and responses of neutrophils. Methods Mol Biol. 2014; 1124:121-58.
    View in: PubMed
    Score: 0.099
  58. Potential, pH, and arachidonate gate hydrogen ion currents in human neutrophils. Biophys J. 1993 Oct; 65(4):1590-8.
    View in: PubMed
    Score: 0.097
  59. Construction and validation of a homology model of the human voltage-gated proton channel hHV1. J Gen Physiol. 2013 Apr; 141(4):445-65.
    View in: PubMed
    Score: 0.094
  60. Voltage-gated proton channels. Compr Physiol. 2012 Apr; 2(2):1355-85.
    View in: PubMed
    Score: 0.088
  61. Hydrogen ion currents in rat alveolar epithelial cells. Biophys J. 1991 Nov; 60(5):1243-53.
    View in: PubMed
    Score: 0.085
  62. pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1. Trends Cell Biol. 2011 Jan; 21(1):20-8.
    View in: PubMed
    Score: 0.079
  63. HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species. Nat Immunol. 2010 Mar; 11(3):265-72.
    View in: PubMed
    Score: 0.076
  64. Ion channels in the metabolic regulation of respiratory cells. Clin Chest Med. 1989 Mar; 10(1):25-36.
    View in: PubMed
    Score: 0.071
  65. Potassium currents in rat type II alveolar epithelial cells. J Physiol. 1988 Jan; 395:487-505.
    View in: PubMed
    Score: 0.065
  66. Two types of potassium channels in murine T lymphocytes. J Gen Physiol. 1987 Mar; 89(3):379-404.
    View in: PubMed
    Score: 0.062
  67. Mitogen induction of ion channels in murine T lymphocytes. J Gen Physiol. 1987 Mar; 89(3):405-20.
    View in: PubMed
    Score: 0.062
  68. Analysis of electrophysiological properties and responses of neutrophils. Methods Mol Biol. 2007; 412:139-75.
    View in: PubMed
    Score: 0.061
  69. The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels. J Gen Physiol. 2006 Jun; 127(6):659-72.
    View in: PubMed
    Score: 0.058
  70. Voltage-dependent ion channels in T-lymphocytes. J Neuroimmunol. 1985 Nov; 10(1):71-95.
    View in: PubMed
    Score: 0.056
  71. Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis? Nature. 1984 Feb 2-8; 307(5950):465-8.
    View in: PubMed
    Score: 0.050
  72. Voltage-activated proton currents in human lymphocytes. J Physiol. 2002 11 15; 545(1):93-105.
    View in: PubMed
    Score: 0.046
  73. Sodium currents in human skeletal muscle fibers. Muscle Nerve. 1982 Oct; 5(8):614-8.
    View in: PubMed
    Score: 0.045
  74. Unexpected expansion of the voltage-gated proton channel family. FEBS J. 2023 02; 290(4):1008-1026.
    View in: PubMed
    Score: 0.045
  75. Dependence of membrane potential on extracellular ionic concentrations in myotonic goats and rats. Am J Physiol. 1981 Jan; 240(1):C56-63.
    View in: PubMed
    Score: 0.040
  76. Ion channels in T lymphocytes. Adv Exp Med Biol. 1987; 213:85-101.
    View in: PubMed
    Score: 0.015
  77. Altered K+ channel expression in abnormal T lymphocytes from mice with the lpr gene mutation. Science. 1986 Sep 12; 233(4769):1197-200.
    View in: PubMed
    Score: 0.015
  78. Electroimmunology: the physiologic role of ion channels in the immune system. J Immunol. 1985 Aug; 135(2 Suppl):787s-791s.
    View in: PubMed
    Score: 0.014
  79. Ion channels in lymphocytes. J Clin Immunol. 1985 Jan; 5(1):1-6.
    View in: PubMed
    Score: 0.013
  80. A voltage-gated potassium channel in human T lymphocytes. J Physiol. 1985 Jan; 358:197-237.
    View in: PubMed
    Score: 0.013
  81. Voltage-gated potassium channels are required for human T lymphocyte activation. J Exp Med. 1984 Aug 01; 160(2):369-85.
    View in: PubMed
    Score: 0.013
  82. Inward rectifier current noise in frog skeletal muscle. J Physiol. 1984 Apr; 349:299-327.
    View in: PubMed
    Score: 0.013
  83. Potassium current noise induced by barium ions in frog skeletal muscle. J Physiol. 1984 Apr; 349:329-51.
    View in: PubMed
    Score: 0.013
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