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Tibor Glant to Proteoglycans

This is a "connection" page, showing publications Tibor Glant has written about Proteoglycans.
Connection Strength

8.158
  1. T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice. Clin Exp Immunol. 2012 Feb; 167(2):346-55.
    View in: PubMed
    Score: 0.358
  2. Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis. Arthritis Rheum. 2011 May; 63(5):1312-21.
    View in: PubMed
    Score: 0.340
  3. BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance. Arthritis Res Ther. 2009; 11(1):R21.
    View in: PubMed
    Score: 0.291
  4. Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan. Clin Exp Immunol. 2005 Nov; 142(2):303-11.
    View in: PubMed
    Score: 0.232
  5. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis. Cell Immunol. 2005 Jun; 235(2):98-108.
    View in: PubMed
    Score: 0.230
  6. Genetic control of experimental spondylarthropathy. Arthritis Rheum. 2005 Aug; 52(8):2452-60.
    View in: PubMed
    Score: 0.228
  7. Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background. Arthritis Rheum. 2004 Jun; 50(6):1984-95.
    View in: PubMed
    Score: 0.210
  8. Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis. Am J Med Sci. 2004 Apr; 327(4):188-95.
    View in: PubMed
    Score: 0.208
  9. Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis. Methods Mol Med. 2004; 102:313-38.
    View in: PubMed
    Score: 0.204
  10. Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan. Arthritis Rheum. 2003 Oct; 48(10):2959-73.
    View in: PubMed
    Score: 0.201
  11. Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency. J Biol Chem. 2003 Oct 03; 278(40):39214-23.
    View in: PubMed
    Score: 0.195
  12. Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics. Crit Rev Immunol. 2003; 23(3):199-250.
    View in: PubMed
    Score: 0.191
  13. Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis. J Immunol. 2001 Apr 15; 166(8):4981-6.
    View in: PubMed
    Score: 0.169
  14. Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease. Arthritis Rheum. 2001 Mar; 44(3):682-92.
    View in: PubMed
    Score: 0.168
  15. Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines. J Immunol. 1999 Nov 15; 163(10):5383-90.
    View in: PubMed
    Score: 0.153
  16. Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse. J Neuroinflammation. 2018 Dec 03; 15(1):335.
    View in: PubMed
    Score: 0.144
  17. Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage. Arthritis Rheum. 1998 Jun; 41(6):1007-18.
    View in: PubMed
    Score: 0.139
  18. Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation. J Immunol. 1998 Apr 15; 160(8):3812-9.
    View in: PubMed
    Score: 0.137
  19. Changes in messenger RNA and protein levels of proteoglycans and link protein in human osteoarthritic cartilage samples. Arthritis Rheum. 1997 Jun; 40(6):1037-45.
    View in: PubMed
    Score: 0.129
  20. Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis. BMC Musculoskelet Disord. 2017 05 30; 18(1):228.
    View in: PubMed
    Score: 0.129
  21. Species-specific alternative splicing of the epidermal growth factor-like domain 1 of cartilage aggrecan. Biochem J. 1996 Nov 01; 319 ( Pt 3):935-40.
    View in: PubMed
    Score: 0.124
  22. Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis. PLoS One. 2016; 11(7):e0160284.
    View in: PubMed
    Score: 0.122
  23. A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice. J Immunol. 1995 Sep 01; 155(5):2679-87.
    View in: PubMed
    Score: 0.115
  24. Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis. Clin Exp Immunol. 1995 Sep; 101(3):414-21.
    View in: PubMed
    Score: 0.115
  25. Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage. Arthritis Rheum. 1995 May; 38(5):660-8.
    View in: PubMed
    Score: 0.112
  26. Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis. Clin Exp Immunol. 1995 Apr; 100(1):104-10.
    View in: PubMed
    Score: 0.111
  27. Interferon-gamma but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma. Immunol Lett. 1995 Feb; 45(1-2):87-91.
    View in: PubMed
    Score: 0.110
  28. Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis. Scand J Rheumatol Suppl. 1995; 101:43-9.
    View in: PubMed
    Score: 0.109
  29. Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice. Cell Immunol. 1994 Oct 15; 158(2):292-304.
    View in: PubMed
    Score: 0.108
  30. Complete coding sequence, deduced primary structure, chromosomal localization, and structural analysis of murine aggrecan. Genomics. 1994 Jul 15; 22(2):364-71.
    View in: PubMed
    Score: 0.106
  31. Effect of pregnancy on proteoglycan-induced progressive polyarthritis in BALB/c mice: remission of disease activity. Clin Exp Immunol. 1993 Nov; 94(2):252-60.
    View in: PubMed
    Score: 0.101
  32. Expression of alternatively spliced epidermal growth factor-like domains in aggrecans of different species. Evidence for a novel module. J Biol Chem. 1993 Aug 15; 268(23):17377-83.
    View in: PubMed
    Score: 0.099
  33. Substrate specificity of 'elastomucoproteinase': an enzyme which can degrade cartilage aggrecan. Biochim Biophys Acta. 1993 Mar 26; 1162(3):266-74.
    View in: PubMed
    Score: 0.097
  34. Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis. Genes Immun. 2012 Jun; 13(4):336-45.
    View in: PubMed
    Score: 0.090
  35. Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases. Biochem Soc Trans. 1990 Oct; 18(5):796-9.
    View in: PubMed
    Score: 0.082
  36. Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice. Arthritis Rheum. 2010 Oct; 62(10):2984-94.
    View in: PubMed
    Score: 0.082
  37. Animals lacking link protein have attenuated perineuronal nets and persistent plasticity. Brain. 2010 Aug; 133(Pt 8):2331-47.
    View in: PubMed
    Score: 0.080
  38. Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints. Arthritis Res Ther. 2010; 12(2):R44.
    View in: PubMed
    Score: 0.079
  39. Epitopes of cartilage core proteins and GAG pattern in human non-Hodgkin lymphoma xenografts. In Vivo. 1990 Mar-Apr; 4(2):149-52.
    View in: PubMed
    Score: 0.078
  40. IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis. J Immunol. 2010 Feb 01; 184(3):1552-9.
    View in: PubMed
    Score: 0.077
  41. Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis. J Leukoc Biol. 2009 Apr; 85(4):711-8.
    View in: PubMed
    Score: 0.072
  42. Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation. Genes Immun. 2008 Oct; 9(7):591-601.
    View in: PubMed
    Score: 0.070
  43. Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation. J Immunol. 2008 Jul 15; 181(2):1307-14.
    View in: PubMed
    Score: 0.070
  44. The structure and abundance of cartilage proteoglycans during early development of the human fetus. Pediatr Res. 1987 Oct; 22(4):409-13.
    View in: PubMed
    Score: 0.066
  45. Proteoglycan epitopes as potential markers of normal and pathologic cartilage metabolism. Arthritis Rheum. 1987 May; 30(5):586-8.
    View in: PubMed
    Score: 0.064
  46. Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology. Arthritis Rheum. 1987 Feb; 30(2):201-12.
    View in: PubMed
    Score: 0.063
  47. Expression of CD44 and L-selectin in the innate immune system is required for severe joint inflammation in the proteoglycan-induced murine model of rheumatoid arthritis. J Immunol. 2006 Aug 01; 177(3):1932-40.
    View in: PubMed
    Score: 0.061
  48. Age-related changes in protein-related epitopes of human articular-cartilage proteoglycans. Biochem J. 1986 May 15; 236(1):71-5.
    View in: PubMed
    Score: 0.060
  49. Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans. Biochem J. 1986 Feb 15; 234(1):31-41.
    View in: PubMed
    Score: 0.059
  50. Naive transgenic T cells expressing cartilage proteoglycan-specific TCR induce arthritis upon in vivo activation. J Autoimmun. 2005 Nov; 25(3):172-80.
    View in: PubMed
    Score: 0.058
  51. A longitudinal study on an autoimmune murine model of ankylosing spondylitis. Ann Rheum Dis. 2005 Jul; 64(7):981-7.
    View in: PubMed
    Score: 0.055
  52. Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation. Arthritis Res Ther. 2005; 7(2):R196-207.
    View in: PubMed
    Score: 0.055
  53. Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice. Arthritis Rheum. 2004 Sep; 50(9):3012-22.
    View in: PubMed
    Score: 0.053
  54. Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones. J Immunol. 2003 Sep 15; 171(6):3025-33.
    View in: PubMed
    Score: 0.050
  55. Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels. J Orthop Res. 2003 Jul; 21(4):730-7.
    View in: PubMed
    Score: 0.049
  56. Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci. J Immunol. 2003 Mar 01; 170(5):2283-92.
    View in: PubMed
    Score: 0.048
  57. TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage. Osteoarthritis Cartilage. 2003 Mar; 11(3):167-76.
    View in: PubMed
    Score: 0.048
  58. Localization of antigenic components in proteoglycan aggregate of bovine nasal cartilage. Histochemistry. 1983; 77(2):217-32.
    View in: PubMed
    Score: 0.048
  59. Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice. Clin Exp Immunol. 2002 Aug; 129(2):224-31.
    View in: PubMed
    Score: 0.046
  60. T and B cell recovery in arthritis adoptively transferred to SCID mice: antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system. J Immunol. 2002 Jun 15; 168(12):6013-21.
    View in: PubMed
    Score: 0.046
  61. Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis. Immunogenetics. 2002 Jun; 54(3):184-92.
    View in: PubMed
    Score: 0.046
  62. Concanavalin A-binding link protein in the proteoglycan aggregate of hyaline cartilage. Biochem Biophys Res Commun. 1982 May 14; 106(1):158-63.
    View in: PubMed
    Score: 0.046
  63. Induction of cartilage degradation in experimental arthritis produced by allogeneic and xenogeneic proteoglycan antigens. Connect Tissue Res. 1982; 9(3):137-44.
    View in: PubMed
    Score: 0.044
  64. Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis. Am J Pathol. 2001 Nov; 159(5):1711-21.
    View in: PubMed
    Score: 0.044
  65. Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis. Arthritis Res. 2002; 4(1):54-8.
    View in: PubMed
    Score: 0.044
  66. A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis. J Immunol. 2000 Nov 01; 165(9):5278-86.
    View in: PubMed
    Score: 0.041
  67. Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis. Clin Exp Immunol. 2000 Apr; 120(1):167-73.
    View in: PubMed
    Score: 0.039
  68. Experimental arthritis produced by proteoglycan antigens in rabbits. Scand J Rheumatol. 1980; 9(4):271-9.
    View in: PubMed
    Score: 0.039
  69. Immunopathologic role of proteoglycan antigens in rheumatoid joint disease. Scand J Immunol. 1980; 11(3):247-52.
    View in: PubMed
    Score: 0.039
  70. The localization of proteoglycans and glycoproteins in the hyaline cartilage. Histochemistry. 1977 Sep 22; 53(4):291-9.
    View in: PubMed
    Score: 0.033
  71. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis. Nat Med. 1995 Jun; 1(6):558-63.
    View in: PubMed
    Score: 0.028
  72. VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis. J Clin Invest. 1995 May; 95(5):2178-86.
    View in: PubMed
    Score: 0.028
  73. Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow. PLoS One. 2014; 9(11):e111815.
    View in: PubMed
    Score: 0.027
  74. Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis. Arthritis Rheum. 1994 Sep; 37(9):1395-403.
    View in: PubMed
    Score: 0.027
  75. Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment. Arthritis Rheumatol. 2014 Feb; 66(2):350-6.
    View in: PubMed
    Score: 0.026
  76. Location of CD4+ T cell priming regulates the differentiation of Th1 and Th17 cells and their contribution to arthritis. J Immunol. 2013 Jun 01; 190(11):5423-35.
    View in: PubMed
    Score: 0.024
  77. Functional assessment of joint use in experimental inflammatory murine arthritis. J Orthop Res. 1993 Mar; 11(2):172-80.
    View in: PubMed
    Score: 0.024
  78. Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Res Ther. 2012 Nov 22; 14(6):R253.
    View in: PubMed
    Score: 0.024
  79. In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis. Cell Immunol. 2012 Jul-Aug; 278(1-2):158-65.
    View in: PubMed
    Score: 0.023
  80. Serum keratan sulfate--a marker of predisposition to polyarticular osteoarthritis. Clin Biochem. 1992 Jun; 25(3):175-80.
    View in: PubMed
    Score: 0.023
  81. Immunomodulation of proteoglycan-induced progressive polyarthritis by leflunomide. Immunopharmacology. 1992 Mar-Apr; 23(2):105-16.
    View in: PubMed
    Score: 0.022
  82. B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis. J Immunol. 2011 Nov 01; 187(9):4900-6.
    View in: PubMed
    Score: 0.022
  83. Chondrons from articular cartilage. (IV). Immunolocalization of proteoglycan epitopes in isolated canine tibial chondrons. J Histochem Cytochem. 1991 Sep; 39(9):1175-87.
    View in: PubMed
    Score: 0.022
  84. Circulating keratan sulfate: a marker of cartilage proteoglycan catabolism in osteoarthritis. J Rheumatol Suppl. 1991 Feb; 27:24-6.
    View in: PubMed
    Score: 0.021
  85. Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice. Arthritis Rheum. 1990 Jun; 33(6):866-76.
    View in: PubMed
    Score: 0.020
  86. Proteoglycan-targeted antibodies as markers on non-Hodgkin lymphoma xenografts. Cancer Immunol Immunother. 1990; 32(2):137-42.
    View in: PubMed
    Score: 0.019
  87. The genetic background of ankylosing spondylitis. Joint Bone Spine. 2009 Dec; 76(6):623-8.
    View in: PubMed
    Score: 0.019
  88. IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis. PLoS One. 2009; 4(1):e4186.
    View in: PubMed
    Score: 0.018
  89. Isolation of proteoglycan-specific T lymphocytes from patients with ankylosing spondylitis. Cell Immunol. 1988 Mar; 112(1):55-63.
    View in: PubMed
    Score: 0.017
  90. Cartilage proteoglycans as potential autoantigens in humans and in experimental animals. Agents Actions. 1988 Feb; 23(1-2):63-6.
    View in: PubMed
    Score: 0.017
  91. The identification and characterization of two populations of aggregating proteoglycans of high buoyant density isolated from post-natal human articular cartilages of different ages. Biochem J. 1987 Dec 15; 248(3):735-40.
    View in: PubMed
    Score: 0.017
  92. Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response. Arthritis Rheum. 2007 Mar; 56(3):861-70.
    View in: PubMed
    Score: 0.016
  93. Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan. Arthritis Rheum. 1987 Mar; 30(3):306-18.
    View in: PubMed
    Score: 0.016
  94. Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy. J Immunol. 2005 Aug 15; 175(4):2475-83.
    View in: PubMed
    Score: 0.014
  95. Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. J Immunol. 2005 Mar 15; 174(6):3781-8.
    View in: PubMed
    Score: 0.014
  96. Antigenicity of bone tissue. I. Immunological and immunohistochemical study of non-collagenous proteins of the bovine cortical bone. Acta Morphol Acad Sci Hung. 1975; 23(2):111-22.
    View in: PubMed
    Score: 0.007
  97. Differentiation antigens of human articular chondrocytes and their tissue distribution as assessed by monoclonal antibodies. J Autoimmun. 1994 Apr; 7(2):203-17.
    View in: PubMed
    Score: 0.006
  98. Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis. Arthritis Rheum. 1990 Sep; 33(9):1394-405.
    View in: PubMed
    Score: 0.005
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