Howard An to Intervertebral Disc
This is a "connection" page, showing publications Howard An has written about Intervertebral Disc.
Connection Strength
13.381
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Small molecule antagonist of C-C chemokine receptor 1 (CCR1) reduces disc inflammation in the rabbit model. Spine J. 2020 12; 20(12):2025-2036.
Score: 0.649
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Intervertebral Disc Cells Produce Interleukins Found in Patients with Back Pain. Am J Phys Med Rehabil. 2016 06; 95(6):407-15.
Score: 0.488
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Histological features of endplates of the mammalian spine: from mice to men. Spine (Phila Pa 1976). 2014 Mar 01; 39(5):E312-7.
Score: 0.418
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Cytotoxicity of local anesthetics and nonionic contrast agents on bovine intervertebral disc cells cultured in a three-dimensional culture system. Spine J. 2014 Mar 01; 14(3):491-8.
Score: 0.409
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Retroperitoneal approach to the intervertebral disc for the annular puncture model of intervertebral disc degeneration in the rabbit. Spine J. 2013 Mar; 13(3):229-34.
Score: 0.387
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Biologic repair and regeneration of the intervertebral disk. J Am Acad Orthop Surg. 2011 Jul; 19(7):450-2.
Score: 0.347
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Intervertebral disk repair by protein, gene, or cell injection: a framework for rehabilitation-focused biologics in the spine. PM R. 2011 Jun; 3(6 Suppl 1):S88-94.
Score: 0.345
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Notochordal cells stimulate migration of cartilage end plate chondrocytes of the intervertebral disc in in vitro cell migration assays. Spine J. 2009 Apr; 9(4):323-9.
Score: 0.283
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Comparative effects of bone morphogenetic proteins and Sox9 overexpression on matrix accumulation by bovine anulus fibrosus cells: implications for anular repair. Spine (Phila Pa 1976). 2007 Nov 01; 32(23):2515-20.
Score: 0.269
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Sensory neurons and fibers from multiple spinal cord levels innervate the rabbit lumbar disc. Am J Phys Med Rehabil. 2006 Nov; 85(11):865-71.
Score: 0.251
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Intradiscal injections of osteogenic protein-1 restore the viscoelastic properties of degenerated intervertebral discs. Spine J. 2006 Nov-Dec; 6(6):692-703.
Score: 0.250
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Intervertebral disc degeneration: biological and biomechanical factors. J Orthop Sci. 2006 Oct; 11(5):541-52.
Score: 0.250
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Artificial disc replacement: progress or hype? Am J Orthop (Belle Mead NJ). 2006 Sep; 35(9):405.
Score: 0.248
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Motion preservation technologies: alternatives to spinal fusion. Am J Orthop (Belle Mead NJ). 2006 Sep; 35(9):411-6.
Score: 0.248
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Prevention of disc degeneration with growth factors. Eur Spine J. 2006 Aug; 15 Suppl 3:S422-32.
Score: 0.247
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Novel model to analyze the effect of a large compressive follower pre-load on range of motions in a lumbar spine. J Biomech. 2007; 40(6):1326-32.
Score: 0.246
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Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model. Spine (Phila Pa 1976). 2006 Apr 01; 31(7):742-54.
Score: 0.241
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Relevance of in vitro and in vivo models for intervertebral disc degeneration. J Bone Joint Surg Am. 2006 Apr; 88 Suppl 2:88-94.
Score: 0.241
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Animal models for human disc degeneration. Spine J. 2005 Nov-Dec; 5(6 Suppl):267S-279S.
Score: 0.234
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Summary statement: biologic repair or regeneration of the intervertebral disc. Spine J. 2005 Nov-Dec; 5(6 Suppl):304S.
Score: 0.234
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Expressions of membrane-type I matrix metalloproteinase, Ki-67 protein, and type II collagen by chondrocytes migrating from cartilage endplate into nucleus pulposus in rat intervertebral discs: a cartilage endplate-fracture model using an intervertebral disc organ culture. Spine (Phila Pa 1976). 2005 Jun 15; 30(12):1373-8.
Score: 0.228
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An autocrine or paracrine Fas-mediated counterattack: a potential mechanism for apoptosis of notochordal cells in intact rat nucleus pulposus. Spine (Phila Pa 1976). 2005 Jun 01; 30(11):1247-51.
Score: 0.228
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Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits. Spine (Phila Pa 1976). 2005 Jan 01; 30(1):25-31; discussion 31-2.
Score: 0.221
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Artificial disc replacement: the new solution for discogenic low back pain? Am J Orthop (Belle Mead NJ). 2005 Jan; 34(1):8-12.
Score: 0.221
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Introduction: disc degeneration: summary. Spine (Phila Pa 1976). 2004 Dec 01; 29(23):2677-8.
Score: 0.220
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Growth factors and treatment of intervertebral disc degeneration. Spine (Phila Pa 1976). 2004 Dec 01; 29(23):2757-69.
Score: 0.220
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Growth factors and the intervertebral disc. Spine J. 2004 Nov-Dec; 4(6 Suppl):330S-340S.
Score: 0.219
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Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation. Spine J. 2003 Nov-Dec; 3(6):451-9.
Score: 0.204
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Cytokine Inhibitors Upregulate Extracellular Matrix Anabolism of Human Intervertebral Discs under Alginate Beads and Alginate-Embedded Explant Cultures. Int J Mol Sci. 2023 Aug 02; 24(15).
Score: 0.201
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Biological repair of intervertebral disc. Spine (Phila Pa 1976). 2003 Aug 01; 28(15 Suppl):S86-92.
Score: 0.201
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The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs. Spine (Phila Pa 1976). 2003 May 15; 28(10):982-90.
Score: 0.198
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Regional distribution of computed tomography attenuation across the lumbar endplate. PLoS One. 2021; 16(10):e0259001.
Score: 0.178
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Changes in Lumbar Endplate Area and Concavity Associated With Disc Degeneration. Spine (Phila Pa 1976). 2018 Oct 01; 43(19):E1127-E1134.
Score: 0.143
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Therapeutic effects of cell therapy with neonatal human dermal fibroblasts and rabbit dermal fibroblasts on disc degeneration and inflammation. Spine J. 2019 01; 19(1):171-181.
Score: 0.142
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Effects of Axial Torsion on Disc Height Distribution: An In Vivo Study. J Manipulative Physiol Ther. 2016 05; 39(4):294-303.
Score: 0.121
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Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion. A prospective multicenter study. Spine (Phila Pa 1976). 1995 Oct 15; 20(20):2211-6.
Score: 0.117
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MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc. Gene. 2015 Jan 25; 555(2):80-7.
Score: 0.109
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Gadolinium-enhancement characteristics of magnetic resonance imaging in distinguishing herniated intervertebral disc versus scar in dogs. Spine (Phila Pa 1976). 1994 Sep 15; 19(18):2089-94; discussion 2095.
Score: 0.108
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Damage accumulation location under cyclic loading in the lumbar disc shifts from inner annulus lamellae to peripheral annulus with increasing disc degeneration. J Biomech. 2014 Jan 03; 47(1):24-31.
Score: 0.102
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Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc. J Cell Physiol. 2013 Sep; 228(9):1884-96.
Score: 0.101
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Human umbilical cord blood-derived mesenchymal stem cells in the cultured rabbit intervertebral disc: a novel cell source for disc repair. Am J Phys Med Rehabil. 2013 May; 92(5):420-9.
Score: 0.099
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Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells. Gene. 2013 07 25; 524(2):282-91.
Score: 0.099
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Toll-like receptor adaptor signaling molecule MyD88 on intervertebral disk homeostasis: in vitro, ex vivo studies. Gene. 2012 Sep 01; 505(2):283-90.
Score: 0.093
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Initiation and progression of mechanical damage in the intervertebral disc under cyclic loading using continuum damage mechanics methodology: A finite element study. J Biomech. 2012 Jul 26; 45(11):1934-40.
Score: 0.093
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Posterior facet load changes in adjacent segments due to moderate and severe degeneration in C5-C6 disc: a poroelastic C3-T1 finite element model study. J Spinal Disord Tech. 2012 Jun; 25(4):218-25.
Score: 0.093
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Lactoferricin mediates anabolic and anti-catabolic effects in the intervertebral disc. J Cell Physiol. 2012 Apr; 227(4):1512-20.
Score: 0.091
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The pathophysiologic role of the protein kinase Cd pathway in the intervertebral discs of rabbits and mice: in vitro, ex vivo, and in vivo studies. Arthritis Rheum. 2012 Jun; 64(6):1950-9.
Score: 0.090
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Progressive disc degeneration at C5-C6 segment affects the mechanics between disc heights and posterior facets above and below the degenerated segment: A flexion-extension investigation using a poroelastic C3-T1 finite element model. Med Eng Phys. 2012 Jun; 34(5):552-8.
Score: 0.088
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Histological features of the degenerating intervertebral disc in a goat disc-injury model. Spine (Phila Pa 1976). 2011 Sep 01; 36(19):1519-27.
Score: 0.088
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The effects of age, sex, ethnicity, and spinal level on the rate of intervertebral disc degeneration: a review of 1712 intervertebral discs. Spine (Phila Pa 1976). 2011 Aug 01; 36(17):1333-9.
Score: 0.087
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Simulation of inhomogeneous rather than homogeneous poroelastic tissue material properties within disc annulus and nucleus better predicts cervical spine response: a C3-T1 finite element model analysis under compression and moment loadings. Spine (Phila Pa 1976). 2011 Feb 15; 36(4):E245-55.
Score: 0.085
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Relative contributions of strain-dependent permeability and fixed charged density of proteoglycans in predicting cervical disc biomechanics: a poroelastic C5-C6 finite element model study. Med Eng Phys. 2011 May; 33(4):438-45.
Score: 0.084
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Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells. Arthritis Rheum. 2010 Dec; 62(12):3706-15.
Score: 0.083
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Patterns of height changes in anterior and posterior cervical disc regions affects the contact loading at posterior facets during moderate and severe disc degeneration: a poroelastic C5-C6 finite element model study. Spine (Phila Pa 1976). 2010 Aug 15; 35(18):E873-81.
Score: 0.082
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Fibronectin splicing variants in human intervertebral disc and association with disc degeneration. Spine (Phila Pa 1976). 2010 Aug 01; 35(17):1581-8.
Score: 0.081
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The relationship of intrapsoas nerves during a transpsoas approach to the lumbar spine: anatomic study. J Spinal Disord Tech. 2010 Jun; 23(4):223-8.
Score: 0.081
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Primary bovine intervertebral disc cells transduced with adenovirus overexpressing 12 BMPs and Sox9 maintain appropriate phenotype. Am J Phys Med Rehabil. 2009 Jun; 88(6):455-63.
Score: 0.075
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Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):10-6.
Score: 0.073
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The action of resveratrol, a phytoestrogen found in grapes, on the intervertebral disc. Spine (Phila Pa 1976). 2008 Nov 15; 33(24):2586-95.
Score: 0.072
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Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis. Gene. 2008 Aug 15; 420(1):82-9.
Score: 0.070
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Action of fibroblast growth factor-2 on the intervertebral disc. Arthritis Res Ther. 2008; 10(2):R48.
Score: 0.070
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Cell therapy using articular chondrocytes overexpressing BMP-7 or BMP-10 in a rabbit disc organ culture model. Spine (Phila Pa 1976). 2008 Apr 15; 33(8):831-8.
Score: 0.069
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Relationship between disc injury and manual lifting: a poroelastic finite element model study. Proc Inst Mech Eng H. 2008 Feb; 222(2):195-207.
Score: 0.069
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Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration. Spine (Phila Pa 1976). 2007 Nov 01; 32(23):2596-603.
Score: 0.067
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Recombinant human osteogenic protein-1 upregulates proteoglycan metabolism of human anulus fibrosus and nucleus pulposus cells. Spine (Phila Pa 1976). 2007 May 20; 32(12):1303-9; discussion 1310.
Score: 0.065
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Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC. Spine (Phila Pa 1976). 2007 May 15; 32(11):1197-205.
Score: 0.065
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Proinflammatory cytokines stimulate the expression of nerve growth factor by human intervertebral disc cells. Spine (Phila Pa 1976). 2007 Mar 15; 32(6):635-42.
Score: 0.064
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The expression of NG2 proteoglycan in the human intervertebral disc. Spine (Phila Pa 1976). 2007 Feb 01; 32(3):306-14.
Score: 0.064
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Effects of growth differentiation factor-5 on the intervertebral disc--in vitro bovine study and in vivo rabbit disc degeneration model study. Spine (Phila Pa 1976). 2006 Dec 01; 31(25):2909-17.
Score: 0.063
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Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells. Spine (Phila Pa 1976). 2006 Sep 01; 31(19):2173-9.
Score: 0.062
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Comparison of cellular response in bovine intervertebral disc cells and articular chondrocytes: effects .of lipopolysaccharide on proteoglycan metabolism. Cell Tissue Res. 2006 Dec; 326(3):787-93.
Score: 0.061
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Platelet-rich plasma (PRP) stimulates the extracellular matrix metabolism of porcine nucleus pulposus and anulus fibrosus cells cultured in alginate beads. Spine (Phila Pa 1976). 2006 Apr 20; 31(9):959-66.
Score: 0.061
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Directions for future research. J Bone Joint Surg Am. 2006 Apr; 88 Suppl 2:110-4.
Score: 0.060
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Intervertebral disc degeneration. Summary of an AAOS/NIH/ORS workshop, September 2005. J Bone Joint Surg Am. 2006 Apr; 88(4):895-9.
Score: 0.060
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Transduced bovine articular chondrocytes affect the metabolism of cocultured nucleus pulposus cells in vitro: implications for chondrocyte transplantation into the intervertebral disc. Spine (Phila Pa 1976). 2005 Dec 01; 30(23):2601-7.
Score: 0.059
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Exposure to pulsed low intensity ultrasound stimulates extracellular matrix metabolism of bovine intervertebral disc cells cultured in alginate beads. Spine (Phila Pa 1976). 2005 Nov 01; 30(21):2398-405.
Score: 0.059
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Low-dose interleukin-1 partially counteracts osteogenic protein-1-induced proteoglycan synthesis by adult bovine intervertebral disk cells. Am J Phys Med Rehabil. 2005 May; 84(5):322-9.
Score: 0.057
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Osteogenic protein-1 is most effective in stimulating nucleus pulposus and annulus fibrosus cells to repair their matrix after chondroitinase ABC-induced in vitro chemonucleolysis. Spine J. 2005 May-Jun; 5(3):231-8.
Score: 0.057
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Differential effects of fibronectin fragment on proteoglycan metabolism by intervertebral disc cells: a comparison with articular chondrocytes. Spine (Phila Pa 1976). 2005 Apr 01; 30(7):722-8.
Score: 0.056
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A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration. Spine (Phila Pa 1976). 2005 Jan 01; 30(1):5-14.
Score: 0.055
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Growth factor osteogenic protein-1: differing effects on cells from three distinct zones in the bovine intervertebral disc. Am J Phys Med Rehabil. 2004 Jul; 83(7):515-21.
Score: 0.053
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Biologic treatment for intervertebral disc degeneration: summary statement. Spine (Phila Pa 1976). 2003 Aug 01; 28(15 Suppl):S99.
Score: 0.050
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Effects of slip severity and loading directions on the stability of isthmic spondylolisthesis: a finite element model study. Spine (Phila Pa 1976). 2003 Jun 01; 28(11):1103-12.
Score: 0.050
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The relationship between disc degeneration, facet joint osteoarthritis, and stability of the degenerative lumbar spine. J Spinal Disord. 2000 Oct; 13(5):444-50.
Score: 0.041
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The anatomic relation among the nerve roots, intervertebral foramina, and intervertebral discs of the cervical spine. Spine (Phila Pa 1976). 2000 Feb 01; 25(3):286-91.
Score: 0.039
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Flexibility of lumbar spinal motion segments correlated to type of tears in the annulus fibrosus. J Neurosurg. 2000 Jan; 92(1 Suppl):81-6.
Score: 0.039
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Comparison of Stand-alone Lateral Lumbar Interbody Fusion Versus Open Laminectomy and Posterolateral Instrumented Fusion in the Treatment of Adjacent Segment Disease Following Previous Lumbar Fusion Surgery. Spine (Phila Pa 1976). 2019 Dec 15; 44(24):E1461-E1469.
Score: 0.039
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Anti-inflammatory effects of interleukin-4 on intervertebral disc cells. Spine J. 2020 01; 20(1):60-68.
Score: 0.038
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The relationship between facet joint osteoarthritis and disc degeneration of the lumbar spine: an MRI study. Eur Spine J. 1999; 8(5):396-401.
Score: 0.037
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The stiffness of lumbar spinal motion segments with a high-intensity zone in the anulus fibrosus. Spine (Phila Pa 1976). 1998 Oct 15; 23(20):2167-73.
Score: 0.036
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Occult lumbar lateral spinal stenosis in neural foramina subjected to physiologic loading. AJNR Am J Neuroradiol. 1996 Oct; 17(9):1605-14.
Score: 0.031
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The ideal amount of lumbar foraminal distraction for pedicle screw instrumentation. Spine (Phila Pa 1976). 1996 Oct 01; 21(19):2218-23.
Score: 0.031
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Rho-Associated Kinase Inhibitor Immortalizes Rat Nucleus Pulposus and Annulus Fibrosus Cells: Establishment of Intervertebral Disc Cell Lines With Novel Approaches. Spine (Phila Pa 1976). 2016 Mar; 41(5):E255-61.
Score: 0.030
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Lumbar foraminal stenosis: critical heights of the intervertebral discs and foramina. A cryomicrotome study in cadavera. J Bone Joint Surg Am. 1995 Jan; 77(1):32-8.
Score: 0.028
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Ideal thickness of Smith-Robinson graft for anterior cervical fusion. A cadaveric study with computed tomographic correlation. Spine (Phila Pa 1976). 1993 Oct 15; 18(14):2043-7.
Score: 0.025
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Fibroblast growth factor control of cartilage homeostasis. J Cell Biochem. 2013 Apr; 114(4):735-42.
Score: 0.024
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Biological treatment for degenerative disc disease: implications for the field of physical medicine and rehabilitation. Am J Phys Med Rehabil. 2008 Sep; 87(9):694-702.
Score: 0.018
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Axonal growth potential of lumbar dorsal root ganglion neurons in an organ culture system: response of nerve growth factor-sensitive neurons to neuronal injury and an inflammatory cytokine. Spine (Phila Pa 1976). 2007 Apr 15; 32(8):857-63.
Score: 0.016
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Nerve fiber ingrowth into scar tissue formed following nucleus pulposus extrusion in the rabbit anular-puncture disc degeneration model: effects of depth of puncture. Spine (Phila Pa 1976). 2006 Oct 01; 31(21):E774-80.
Score: 0.016
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The effect of disc degeneration and facet joint osteoarthritis on the segmental flexibility of the lumbar spine. Spine (Phila Pa 1976). 2000 Dec 01; 25(23):3036-44.
Score: 0.010
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The effect of age on inflammatory responses and nerve root injuries after lumbar disc herniation: an experimental study in a canine model. Spine (Phila Pa 1976). 2000 Apr 15; 25(8):937-40.
Score: 0.010