D012326PhysiologyG02.111.760.700G03.839.700G05.308.700.7007110.995404RNA SplicingFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31038472Gallagher PG, Maksimova Y, Lezon-Geyda K, Newburger PE, Medeiros D, Hanson RD, Rothman J, Israels S, Wall DA, Sidonio RF, Sieff C, Gowans LK, Mittal N, Rivera-Santiago R, Speicher DW, Baserga SJ, Schulz VPThe Journal of clinical investigationAberrant splicing contributes to severe a-spectrin-linked congenital hemolytic anemia. J Clin Invest. 2019 04 30; 129(7):2878-2887.J Clin Invest2019-04-30T00:00:002019Aberrant splicing contributes to severe a-spectrin-linked congenital hemolytic anemia.true1Associate ProfessorAssociate Professor18065781Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus SHuman molecular geneticsSex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease. Hum Mol Genet. 2008 Apr 01; 17(7):929-35.Hum Mol Genet2007-12-08T00:00:002007Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.31597093Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JMCell reportsTau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.Cell Rep2019-10-08T00:00:002019Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.26902204Hinrich AJ, Jodelka FM, Chang JL, Brutman D, Bruno AM, Briggs CA, James BD, Stutzmann GE, Bennett DA, Miller SA, Rigo F, Marr RA, Hastings MLEMBO molecular medicineTherapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense?oligonucleotides. EMBO Mol Med. 2016 04 01; 8(4):328-45.EMBO Mol Med2016-04-01T00:00:002016Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense?oligonucleotides.0.4485330.005017027research area of0.733520.020160811subject area forPediatricsBrandonBartonBrandon Barton349171Barton, BrandonAssistant Professor6Assistant Professor5Associate Professor4Professor33097395Johnstone T, Wang J, Ross D, Balanda N, Huang Y, Godfrey R, Groden C, Barton BR, Gahl W, Toro C, Malicdan MCVMolecular genetics and metabolismBiallelic variants in two complex I genes cause abnormal splicing defects in probands with mild Leigh syndrome. Mol Genet Metab. 2020 Sep - Oct; 131(1-2):98-106.Mol Genet Metab2020-10-14T00:00:002020Biallelic variants in two complex I genes cause abnormal splicing defects in probands with mild Leigh syndrome.Internal MedicineNeurological SciencesRush University, Rush Medical CollegeDavidBennettDavid A. Bennett41.87328300000000-87.66936330000000349004Bennett, DavidProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorIgorKoralnikIgor J. Koralnik349837Koralnik, IgorProfessorNupurMittalNupur Mittal349863Mittal, NupurAssistant Professortrue1ProfessorProfessorBryanJamesBryan D. James41.87432800000000-87.67059170000000350039James, BryanAssociate Professortrue1Assistant ProfessorAssistant Professor