D017398Chemicals & DrugsPhysiologyG02.111.760.700.100G03.839.700.100G05.308.700.700.10016250.991083Alternative SplicingFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson30297968Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PLNature geneticsIntegrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nat Genet. 2018 11; 50(11):1584-1592.Nat Genet2018-10-08T00:00:002018Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.990.7788070.01070816research area of0.6844310.02917820subject area fortrue1ProfessorProfessorTiborGlantTibor Glant41.87386750000000-87.67102690000000349069Glant, TiborProfessorDavidWilliamsDavid Lee Williams349574Williams, DavidAssociate ProfessorKathrinBanachKathrin Banach349610Banach, KathrinAssistant Professor6Assistant Professor5Associate Professor4Professor15269137He X, Ee PL, Coon JS, Beck WTClinical cancer research : an official journal of the American Association for Cancer ResearchAlternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20. Clin Cancer Res. 2004 Jul 15; 10(14):4652-60.Clin Cancer Res2004-07-15T00:00:002004Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20.21790734Nesterovitch AB, Hoffman MD, Simon M, Petukhov PA, Tharp MD, Glant TTClinical and experimental dermatologyMutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum. Clin Exp Dermatol. 2011 Dec; 36(8):889-95.Clin Exp Dermatol2011-07-25T00:00:002011Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum.17901361Shang LL, Pfahnl AE, Sanyal S, Jiao Z, Allen J, Banach K, Fahrenbach J, Weiss D, Taylor WR, Zafari AM, Dudley SCCirculation researchHuman heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel. Circ Res. 2007 Nov 26; 101(11):1146-54.Circ Res2007-09-27T00:00:002007Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel.Neurological SciencesOrthopedic SurgeryRush University, Rush Medical CollegeDavidBennettDavid A. Bennett41.87328300000000-87.66936330000000349004Bennett, DavidProfessor28232751Funnell T, Tasaki S, Oloumi A, Araki S, Kong E, Yap D, Nakayama Y, Hughes CS, Cheng SG, Tozaki H, Iwatani M, Sasaki S, Ohashi T, Miyazaki T, Morishita N, Morishita D, Ogasawara-Shimizu M, Ohori M, Nakao S, Karashima M, Sano M, Murai A, Nomura T, Uchiyama N, Kawamoto T, Hara R, Nakanishi O, Shumansky K, Rosner J, Wan A, McKinney S, Morin GB, Nakanishi A, Shah S, Toyoshiba H, Aparicio SNature communicationsCLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor. Nat Commun. 2017 02 23; 8(1):7.Nat Commun2017-02-23T00:00:002017CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.true1true1ProfessorProfessorInternal Medicine, Division of CardiologyShinyaTasakiShinya Tasaki350029Tasaki, Shinyatrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate ProfessorMicrobial Pathogens and Immunity