PhDKalipadaPahanKalipada Pahan349039Pahan, KalipadaMy Scopus ID is 7004724512.
My NIH COMMONS name is PAHAN.KALIPADA.Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifierbibo:suffixNamename suffixAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:orcidIdORCID idvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000818Living Beings31945770.519818AnimalsD004681Disorders6430.932643Encephalomyelitis, Autoimmune, ExperimentalAuthorship 32866530187283Rangasamy SB, Dasarathi S, Pahan P, Jana M, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyLow-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson's Disease. J Neuroimmune Pharmacol. 2019 06; 14(2):173-187.J Neuroimmune Pharmacol2018-09-05T00:00:002018Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson's Disease.Authorship 340884Authorship 34189530482850Mondal S, Jana M, Dasarathi S, Roy A, Pahan KScience signalingAspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells. Sci Signal. 2018 11 27; 11(558).Sci Signal2018-11-27T00:00:002018Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells.30530735Yalagala PCR, Sugasini D, Dasarathi S, Pahan K, Subbaiah PVJournal of lipid researchDietary lysophosphatidylcholine-EPA enriches both EPA and DHA in the brain: potential treatment for depression. J Lipid Res. 2019 03; 60(3):566-578.J Lipid Res2018-12-10T00:00:002018Dietary lysophosphatidylcholine-EPA enriches both EPA and DHA in the brain: potential treatment for depression.Authorship 3426011Authorship 34261430578827Chandra S, Roy A, Jana M, Pahan KNeurobiology of diseaseCinnamic acid activates PPARa to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model. Neurobiol Dis. 2019 04; 124:379-395.Neurobiol Dis2018-12-19T00:00:002018Cinnamic acid activates PPARa to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model.30579705Dodiya HB, Forsyth CB, Voigt RM, Engen PA, Patel J, Shaikh M, Green SJ, Naqib A, Roy A, Kordower JH, Pahan K, Shannon KM, Keshavarzian ANeurobiology of diseaseChronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiol Dis. 2020 02; 135:104352.Neurobiol Dis2018-12-21T00:00:002018Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.Authorship 34329430612307Prorok T, Jana M, Patel D, Pahan KNeurochemical researchCinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptora. Neurochem Res. 2019 Apr; 44(4):751-762.Neurochem Res2019-01-05T00:00:002019Cinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptora.Authorship 35060630928643Chakrabarti S, Chandra S, Roy A, Dasarathi S, Kundu M, Pahan KNeurobiology of diseaseUpregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARa: Implications for late-infantile Batten disease therapy. Neurobiol Dis. 2019 07; 127:362-373.Neurobiol Dis2019-03-28T00:00:002019Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARa: Implications for late-infantile Batten disease therapy.Authorship 35334631043478Mondal S, Rangasamy SB, Roy A, Dasarathy S, Kordower JH, Pahan KJournal of immunology (Baltimore, Md. : 1950)Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys. J Immunol. 2019 May 01.J Immunol2019-05-01T00:00:002019Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys.Authorship 355525Authorship 35575431119595Patel D, Jana A, Roy A, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyCinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF. J Neuroimmune Pharmacol. 2019 09; 14(3):503-518.J Neuroimmune Pharmacol2019-05-22T00:00:002019Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF.31127527Gottschalk CG, Roy A, Jana M, Kundu M, Pahan KMolecular neurobiologyActivation of Peroxisome Proliferator-Activated Receptor-a Increases the Expression of Nuclear Receptor Related 1 Protein (Nurr1) in Dopaminergic Neurons. Mol Neurobiol. 2019 Nov; 56(11):7872-7887.Mol Neurobiol2019-05-24T00:00:002019Activation of Peroxisome Proliferator-Activated Receptor-a Increases the Expression of Nuclear Receptor Related 1 Protein (Nurr1) in Dopaminergic Neurons.Authorship 35616231140860Pahan S, Pahan KDNA and cell biologyMode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis. DNA Cell Biol. 2019 Jul; 38(7):593-596.DNA Cell Biol2019-05-28T00:00:002019Mode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis.true1ProfessorProfessor18000063Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaSelective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18754-9.Proc Natl Acad Sci U S A2007-11-13T00:00:002007Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease.26401561Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan KJournal of Alzheimer's disease : JADIntranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2015; 47(2):385-402.J Alzheimers Dis2015-01-01T00:00:002015Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease.27226559Chandra G, Rangasamy SB, Roy A, Kordower JH, Pahan KThe Journal of biological chemistryNeutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease. J Biol Chem. 2016 07 15; 291(29):15267-81.J Biol Chem2016-05-12T00:00:002016Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease.22661311Mondal S, Roy A, Jana A, Ghosh S, Kordower JH, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyTesting NF-?B-based therapy in hemiparkinsonian monkeys. J Neuroimmune Pharmacol. 2012 Sep; 7(3):544-56.J Neuroimmune Pharmacol2012-06-03T00:00:002012Testing NF-?B-based therapy in hemiparkinsonian monkeys.23972989Roy A, Jana M, Corbett GT, Ramaswamy S, Kordower JH, Gonzalez FJ, Pahan KCell reportsRegulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor a. Cell Rep. 2013 Aug 29; 4(4):724-37.Cell Rep2013-08-22T00:00:002013Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor a.Authorship 363956Authorship 36489231273781Chakrabarti S, Roy A, Prorok T, Patel D, Dasarathi S, Pahan KJournal of neurochemistryAspirin up-regulates suppressor of cytokine signaling 3 in glial cells via PPARa. J Neurochem. 2019 10; 151(1):50-63.J Neurochem2019-07-28T00:00:002019Aspirin up-regulates suppressor of cytokine signaling 3 in glial cells via PPARa.31259309Chandra S, Pahan KJournal of Alzheimer's disease reportsGemfibrozil, a Lipid-Lowering Drug, Lowers Amyloid Plaque Pathology and Enhances Memory in a Mouse Model of Alzheimer's Disease via Peroxisome Proliferator-Activated Receptor a. J Alzheimers Dis Rep. 2019 May 18; 3(1):149-168.J Alzheimers Dis Rep2019-05-18T00:00:002019Gemfibrozil, a Lipid-Lowering Drug, Lowers Amyloid Plaque Pathology and Enhances Memory in a Mouse Model of Alzheimer's Disease via Peroxisome Proliferator-Activated Receptor a.Authorship 369157Authorship 371064Authorship 37138931424405Chandra S, Roy A, Patel DR, Pahan KJournal of Alzheimer's disease : JADPPARa Between Aspirin and Plaque Clearance. J Alzheimers Dis. 2019; 71(2):389-397.J Alzheimers Dis2019-01-01T00:00:002019PPARa Between Aspirin and Plaque Clearance.31445159Dutta D, Kundu M, Mondal S, Roy A, Ruehl S, Hall DA, Pahan KNeurobiology of diseaseRANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease. Neurobiol Dis. 2019 12; 132:104575.Neurobiol Dis2019-08-22T00:00:002019RANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease.31578267Drohomyrecky PC, Doroshenko ER, Akkermann R, Moshkova M, Yi TJ, Zhao FL, Ahn JJ, McGaha TL, Pahan K, Dunn SEJournal of immunology (Baltimore, Md. : 1950)Peroxisome Proliferator-Activated Receptor-d Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis. J Immunol. 2019 11 15; 203(10):2588-2601.J Immunol2019-10-02T00:00:002019Peroxisome Proliferator-Activated Receptor-d Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis.Chicago60612IL11209selected publications16.04090.00614629711research areas8.814260.030560917coauthor of704.67237.57560similar toAuthorship 28241Authorship 33831Authorship 27521Authorship 33404Authorship 31492Authorship 30863Authorship 27441Authorship 27401Authorship 27801Authorship 30683Authorship 29662Authorship 32757Authorship 34627Authorship 35534Authorship 27331Authorship 30343Authorship 31126Authorship 29613Authorship 35174Authorship 28996Authorship 30185Authorship 34512Authorship 30972Authorship 31042Authorship 28514Authorship 27312Authorship 30162Authorship 31642Authorship 27782Authorship 33108Authorship 27681Authorship 35904Authorship 27691Authorship 33665Authorship 28695Authorship 33842Authorship 30082Authorship 26821Authorship 30323Authorship 31911Authorship 28181Authorship 32742Authorship 29282Authorship 30352Authorship 27951Authorship 27744Authorship 33622Authorship 31113Authorship 32779Authorship 29601Authorship 33203Authorship 34684Authorship 26871Authorship 27371Authorship 33363Authorship 26961Authorship 30004Authorship 30482Authorship 27321Authorship 33256Authorship 27611Authorship 29082Authorship 33417Authorship 29642Authorship 28795Authorship 30854Authorship 32712Authorship 27732Authorship 28714Authorship 303310Authorship 34245Authorship 32686Authorship 28346Authorship 30762Authorship 33764Authorship 35645Authorship 34949Authorship 28001Authorship 27771Authorship 32733Authorship 26912Authorship 32102Authorship 28131Authorship 32894Authorship 35198Authorship 31282Authorship 27484Authorship 34502Authorship 27892Authorship 27551Authorship 27711Authorship 26861Authorship 34176Authorship 30732Authorship 27632Authorship 34702Authorship 31452Authorship 28507Authorship 27341Authorship 27451Authorship 29052Authorship 28171Authorship 34935Authorship 32592Authorship 28812Authorship 29264Authorship 30986Authorship 27493Authorship 35362Authorship 30553Authorship 31421Authorship 34112Authorship 27852Authorship 28404Authorship 30773Authorship 33095Authorship 27412Authorship 32844Authorship 34893Authorship 28936Authorship 29105Authorship 30255Authorship 30567Authorship 33567Authorship 27721Authorship 29312Authorship 28012Authorship 28161Authorship 30263Authorship 29594Authorship 317829685387Singh I, Pahan K, Khan M, Singh AKThe Journal of biological chemistryCytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. J Biol Chem. 1998 Aug 07; 273(32):20354-62.J Biol Chem1998-08-07T00:00:001998Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.22879602Jana M, Mondal S, Gonzalez FJ, Pahan KThe Journal of biological chemistryGemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-?. J Biol Chem. 2012 Oct 05; 287(41):34134-48.J Biol Chem2012-08-09T00:00:002012Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-?.1378330Pahan K, Gachhui R, Ray S, Chaudhuri J, Mandal ABulletin of environmental contamination and toxicologyBacterial degradation and utilization of merbromine and fluorescein mercuric acetate. Bull Environ Contam Toxicol. 1992 Mar; 48(3):421-7.Bull Environ Contam Toxicol1992-03-01T00:00:001992Bacterial degradation and utilization of merbromine and fluorescein mercuric acetate.22753407Khasnavis S, Jana A, Roy A, Mazumder M, Bhushan B, Wood T, Ghosh S, Watson R, Pahan KThe Journal of biological chemistrySuppression of nuclear factor-?B activation and inflammation in microglia by physically modified saline. J Biol Chem. 2012 Aug 24; 287(35):29529-42.J Biol Chem2012-06-29T00:00:002012Suppression of nuclear factor-?B activation and inflammation in microglia by physically modified saline.27532224Bera S, Kar RK, Mondal S, Pahan K, Bhunia ABiochemistryStructural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier. Biochemistry. 2016 09 06; 55(35):4982-96.Biochemistry2016-08-24T00:00:002016Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier.8543053Pahan K, Khan M, Smith BT, Singh IFEBS lettersKetoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation. FEBS Lett. 1995 Dec 18; 377(2):213-6.FEBS Lett1995-12-18T00:00:001995Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation.17625103Dasgupta S, Roy A, Jana M, Hartley DM, Pahan KMolecular pharmacologyGemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol Pharmacol. 2007 Oct; 72(4):934-46.Mol Pharmacol2007-07-11T00:00:002007Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha.26399250Modi KK, Jana M, Mondal S, Pahan KNeurochemical researchSodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes. Neurochem Res. 2015 Nov; 40(11):2333-47.Neurochem Res2015-09-23T00:00:002015Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes.15063753Auch CJ, Saha RN, Sheikh FG, Liu X, Jacobs BL, Pahan KFEBS lettersRole of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia. FEBS Lett. 2004 Apr 09; 563(1-3):223-8.FEBS Lett2004-04-09T00:00:002004Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia.22706077Corbett GT, Roy A, Pahan KJournal of immunology (Baltimore, Md. : 1950)Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol. 2012 Jul 15; 189(2):1002-13.J Immunol2012-06-15T00:00:002012Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense.9446561Pahan K, Sheikh FG, Khan M, Namboodiri AM, Singh IThe Journal of biological chemistrySphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem. 1998 Jan 30; 273(5):2591-600.J Biol Chem1998-01-30T00:00:001998Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.17512466Saha RN, Pahan KFree radical biology & medicineDifferential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radic Biol Med. 2007 Jun 15; 42(12):1866-78.Free Radic Biol Med2007-03-31T00:00:002007Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia.22528839Jana M, Pahan KNeurochemical researchGemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor ?. Neurochem Res. 2012 Aug; 37(8):1718-29.Neurochem Res2012-04-17T00:00:002012Gemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor ?.9501198Sheikh FG, Pahan K, Khan M, Barbosa E, Singh IProceedings of the National Academy of Sciences of the United States of AmericaAbnormality in catalase import into peroxisomes leads to severe neurological disorder. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2961-6.Proc Natl Acad Sci U S A1998-03-17T00:00:001998Abnormality in catalase import into peroxisomes leads to severe neurological disorder.12690109Dasgupta S, Jana M, Liu X, Pahan KThe Journal of biological chemistryRole of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells. J Biol Chem. 2003 Jun 20; 278(25):22424-31.J Biol Chem2003-04-10T00:00:002003Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells.21425926Pahan KImmunopharmacology and immunotoxicologyImmunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate. Immunopharmacol Immunotoxicol. 2011 Dec; 33(4):586-93.Immunopharmacol Immunotoxicol2011-03-22T00:00:002011Immunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate.23653362Modi KK, Sendtner M, Pahan KThe Journal of biological chemistryUp-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. J Biol Chem. 2013 Jun 21; 288(25):18533-45.J Biol Chem2013-05-07T00:00:002013Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis.8618694Burdette DE, Kremser K, Fink JK, Pahan K, Stanley W, Singh INeurologyLate-onset generalized disorder of peroxisomes. Neurology. 1996 Mar; 46(3):829-31.Neurology1996-03-01T00:00:001996Late-onset generalized disorder of peroxisomes.12871593Jana M, Dasgupta S, Saha RN, Liu X, Pahan KJournal of neurochemistryInduction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. J Neurochem. 2003 Jul; 86(2):519-28.J Neurochem2003-07-01T00:00:002003Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages.16672668Brahmachari S, Fung YK, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceInduction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci. 2006 May 03; 26(18):4930-9.J Neurosci2006-05-03T00:00:002006Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide.19147160Jana A, Hogan EL, Pahan KJournal of the neurological sciencesCeramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death. J Neurol Sci. 2009 Mar 15; 278(1-2):5-15.J Neurol Sci2009-01-14T00:00:002009Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death.16771683Saha RN, Pahan KAntioxidants & redox signalingRegulation of inducible nitric oxide synthase gene in glial cells. Antioxid Redox Signal. 2006 May-Jun; 8(5-6):929-47.Antioxid Redox Signal2006-05-01T00:00:002006Regulation of inducible nitric oxide synthase gene in glial cells.17785853Jana M, Jana A, Liu X, Ghosh S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. J Immunol. 2007 Sep 15; 179(6):4142-52.J Immunol2007-09-15T00:00:002007Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia.19812204Brahmachari S, Jana A, Pahan KJournal of immunology (Baltimore, Md. : 1950)Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. J Immunol. 2009 Nov 01; 183(9):5917-27.J Immunol2009-10-07T00:00:002009Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses.15683721Jana M, Anderson JA, Saha RN, Liu X, Pahan KFree radical biology & medicineRegulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med. 2005 Mar 01; 38(5):655-64.Free Radic Biol Med2005-03-01T00:00:002005Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes.9600263Singh I, Pahan K, Khan MFEBS lettersLovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. FEBS Lett. 1998 Apr 24; 426(3):342-6.FEBS Lett1998-04-24T00:00:001998Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy.1816104Pahan K, Gachhui R, Ray S, Chaudhuri J, Mandal AIndian journal of experimental biologyA PMA degrading constitutive organomercurial lyase in a broad-spectrum mercury resistant Bacillus pasteurii strain DR2. Indian J Exp Biol. 1991 Dec; 29(12):1147-9.Indian J Exp Biol1991-12-01T00:00:001991A PMA degrading constitutive organomercurial lyase in a broad-spectrum mercury resistant Bacillus pasteurii strain DR2.1855005Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal ABulletin of environmental contamination and toxicologyVolatilization of mercury compounds and utilization of various aromatic compounds by a broad-spectrum mercury resistant Bacillus pasteurii strain. Bull Environ Contam Toxicol. 1991 Apr; 46(4):591-8.Bull Environ Contam Toxicol1991-04-01T00:00:001991Volatilization of mercury compounds and utilization of various aromatic compounds by a broad-spectrum mercury resistant Bacillus pasteurii strain.18431321Brahmachari S, Pahan KMinerva medicaRole of cytokine p40 family in multiple sclerosis. Minerva Med. 2008 Apr; 99(2):105-18.Minerva Med2008-04-01T00:00:002008Role of cytokine p40 family in multiple sclerosis.9648853Khan M, Pahan K, Singh AK, Singh IJournal of neurochemistryCytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy. J Neurochem. 1998 Jul; 71(1):78-87.J Neurochem1998-07-01T00:00:001998Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy.20414732Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyNeuroimmune pharmacological control of EAE. J Neuroimmune Pharmacol. 2010 Jun; 5(2):165-7.J Neuroimmune Pharmacol2010-04-23T00:00:002010Neuroimmune pharmacological control of EAE.25569428Mondal S, Pahan KPloS oneCinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy. PLoS One. 2015; 10(1):e0116566.PLoS One2015-01-08T00:00:002015Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy.20861373Jana A, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceFibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. J Neurosci. 2010 Sep 22; 30(38):12676-89.J Neurosci2010-09-22T00:00:002010Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease.22989886Ghosh A, Corbett GT, Gonzalez FJ, Pahan KThe Journal of biological chemistryGemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor a: implications for late infantile Batten disease therapy. J Biol Chem. 2012 Nov 09; 287(46):38922-35.J Biol Chem2012-09-18T00:00:002012Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor a: implications for late infantile Batten disease therapy.9610777Pahan K, Khan M, Singh IJournal of lipid researchTherapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP. J Lipid Res. 1998 May; 39(5):1091-100.J Lipid Res1998-05-01T00:00:001998Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP.25007337Roy A, Modi KK, Khasnavis S, Ghosh S, Watson R, Pahan KPloS oneEnhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS One. 2014; 9(7):e101883.PLoS One2014-07-09T00:00:002014Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase.9065441Pahan K, Namboodiri AM, Sheikh FG, Smith BT, Singh IThe Journal of biological chemistryIncreasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem. 1997 Mar 21; 272(12):7786-91.J Biol Chem1997-03-21T00:00:001997Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes.10428046Pahan K, Dobashi K, Ghosh B, Singh IJournal of neurochemistryInduction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. J Neurochem. 1999 Aug; 73(2):513-20.J Neurochem1999-08-01T00:00:001999Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide.7803482Pahan K, Gulati S, Singh IBiochimica et biophysica actaPhytanic acid alpha-oxidation in rat liver mitochondria. Biochim Biophys Acta. 1994 Dec 15; 1201(3):491-7.Biochim Biophys Acta1994-12-15T00:00:001994Phytanic acid alpha-oxidation in rat liver mitochondria.16568248Pahan KCellular and molecular life sciences : CMLSLipid-lowering drugs. Cell Mol Life Sci. 2006 May; 63(10):1165-78.Cell Mol Life Sci2006-05-01T00:00:002006Lipid-lowering drugs.18040843Jana A, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyOxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis. J Neuroimmune Pharmacol. 2007 Jun; 2(2):184-93.J Neuroimmune Pharmacol2007-03-08T00:00:002007Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis.18582206Dasgupta S, Bandopadhyay M, Pahan KHybridoma (2005)Generation of functional blocking monoclonal antibodies against mouse interleukin-12 p40 homodimer and monomer. Hybridoma (Larchmt). 2008 Jun; 27(3):141-51.Hybridoma (Larchmt)2008-06-01T00:00:002008Generation of functional blocking monoclonal antibodies against mouse interleukin-12 p40 homodimer and monomer.8820111Pahan K, Smith BT, Singh IJournal of lipid researchEpoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis. J Lipid Res. 1996 Jan; 37(1):159-67.J Lipid Res1996-01-01T00:00:001996Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis.23404502Corbett GT, Roy A, Pahan KThe Journal of biological chemistrySodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. J Biol Chem. 2013 Mar 22; 288(12):8299-8312.J Biol Chem2013-02-12T00:00:002013Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.8224157Pahan K, Singh IFEBS lettersIntraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes. FEBS Lett. 1993 Oct 25; 333(1-2):154-8.FEBS Lett1993-10-25T00:00:001993Intraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes.25575492Roy A, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyPPARa signaling in the hippocampus: crosstalk between fat and memory. J Neuroimmune Pharmacol. 2015 Mar; 10(1):30-4.J Neuroimmune Pharmacol2015-01-10T00:00:002015PPARa signaling in the hippocampus: crosstalk between fat and memory.22685291Ghosh A, Pahan KThe Journal of biological chemistryGemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders. J Biol Chem. 2012 Aug 03; 287(32):27189-203.J Biol Chem2012-06-08T00:00:002012Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders.15240729Dasgupta S, Jana M, Zhou Y, Fung YK, Ghosh S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. J Immunol. 2004 Jul 15; 173(2):1344-54.J Immunol2004-07-15T00:00:002004Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis.24224652Jana M, Mondal S, Jana A, Pahan KImmunologyInterleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology. 2014 Apr; 141(4):549-63.Immunology2014-04-01T00:00:002014Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis.24076025Roy A, Pahan KFEBS lettersAnkyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease. FEBS Lett. 2013 Nov 01; 587(21):3567-74.FEBS Lett2013-09-25T00:00:002013Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease.12646656Dasgupta S, Zhou Y, Jana M, Banik NL, Pahan KJournal of immunology (Baltimore, Md. : 1950)Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol. 2003 Apr 01; 170(7):3874-82.J Immunol2003-04-01T00:00:002003Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps.17823123Roy A, Liu X, Pahan KThe Journal of biological chemistryMyelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem. 2007 Nov 02; 282(44):32222-32.J Biol Chem2007-09-06T00:00:002007Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin.24122363Khasnavis S, Roy A, Ghosh S, Watson R, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyProtection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles. J Neuroimmune Pharmacol. 2014 Mar; 9(2):218-32.J Neuroimmune Pharmacol2014-03-01T00:00:002014Protection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles.19306359Jana M, Dasgupta S, Pal U, Pahan KGliaIL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia. 2009 Nov 01; 57(14):1553-65.Glia2009-11-01T00:00:002009IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.12176974Dasgupta S, Jana M, Liu X, Pahan KThe Journal of biological chemistryMyelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. J Biol Chem. 2002 Oct 18; 277(42):39327-33.J Biol Chem2002-08-09T00:00:002002Myelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis.9389730Pahan K, Sheikh FG, Namboodiri AM, Singh IThe Journal of clinical investigationLovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest. 1997 Dec 01; 100(11):2671-9.J Clin Invest1997-12-01T00:00:001997Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages.17579047Brahmachari S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2007 Jul 01; 179(1):275-83.J Immunol2007-07-01T00:00:002007Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis.17982102Saha RN, Jana M, Pahan KJournal of immunology (Baltimore, Md. : 1950)MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol. 2007 Nov 15; 179(10):7101-9.J Immunol2007-11-15T00:00:002007MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65.19596989Saha RN, Ghosh A, Palencia CA, Fung YK, Dudek SM, Pahan KJournal of immunology (Baltimore, Md. : 1950)TNF-alpha preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. J Immunol. 2009 Aug 01; 183(3):2068-78.J Immunol2009-07-13T00:00:002009TNF-alpha preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein.2322662Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal ABulletin of environmental contamination and toxicologyEffect of thiol compounds and flavins on mercury and organomercurial degrading enzymes in mercury resistant aquatic bacteria. Bull Environ Contam Toxicol. 1990 Feb; 44(2):216-23.Bull Environ Contam Toxicol1990-02-01T00:00:001990Effect of thiol compounds and flavins on mercury and organomercurial degrading enzymes in mercury resistant aquatic bacteria.21701815Khasnavis S, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologySodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. J Neuroimmune Pharmacol. 2012 Jun; 7(2):424-35.J Neuroimmune Pharmacol2011-06-24T00:00:002011Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons.26102198Modi KK, Roy A, Brahmachari S, Rangasamy SB, Pahan KPloS oneCinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer's Disease. PLoS One. 2015; 10(6):e0130398.PLoS One2015-06-23T00:00:002015Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer's Disease.19019087Jana M, Pahan KImmunologyInduction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology. 2009 Jul; 127(3):312-25.Immunology2008-11-14T00:00:002008Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70.26080426Corbett GT, Gonzalez FJ, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaActivation of peroxisome proliferator-activated receptor a stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8445-50.Proc Natl Acad Sci U S A2015-06-15T00:00:002015Activation of peroxisome proliferator-activated receptor a stimulates ADAM10-mediated proteolysis of APP.25089827Modi KK, Jana A, Ghosh S, Watson R, Pahan KPloS oneA physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease. PLoS One. 2014; 9(8):e103606.PLoS One2014-08-04T00:00:002014A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease.25750174Ghosh A, Jana M, Modi K, Gonzalez FJ, Sims KB, Berry-Kravis E, Pahan KThe Journal of biological chemistryActivation of peroxisome proliferator-activated receptor a induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. J Biol Chem. 2015 Apr 17; 290(16):10309-24.J Biol Chem2015-03-06T00:00:002015Activation of peroxisome proliferator-activated receptor a induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.8725164Pahan K, Khan M, Singh IJournal of lipid researchPhytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata. J Lipid Res. 1996 May; 37(5):1137-43.J Lipid Res1996-05-01T00:00:001996Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata.9109515Dobashi K, Pahan K, Chahal A, Singh IJournal of neurochemistryModulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells. J Neurochem. 1997 May; 68(5):1896-903.J Neurochem1997-05-01T00:00:001997Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells.10788611Pahan K, Liu X, Wood C, Raymond JRFEBS lettersExpression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes. FEBS Lett. 2000 Apr 28; 472(2-3):203-7.FEBS Lett2000-04-28T00:00:002000Expression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes.16109311Jana M, Pahan KFree radical biology & medicineRedox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radic Biol Med. 2005 Sep 15; 39(6):823-31.Free Radic Biol Med2005-09-15T00:00:002005Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.10899932Pahan K, Khan M, Singh IJournal of neurochemistryInterleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. J Neurochem. 2000 Aug; 75(2):576-82.J Neurochem2000-08-01T00:00:002000Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase.15452132Jana A, Pahan KThe Journal of biological chemistryFibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease. J Biol Chem. 2004 Dec 03; 279(49):51451-9.J Biol Chem2004-09-27T00:00:002004Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease.26118928Roy A, Jana M, Kundu M, Corbett GT, Rangaswamy SB, Mishra RK, Luan CH, Gonzalez FJ, Pahan KCell metabolismHMG-CoA Reductase Inhibitors Bind to PPARa to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice. Cell Metab. 2015 Aug 04; 22(2):253-65.Cell Metab2015-06-25T00:00:002015HMG-CoA Reductase Inhibitors Bind to PPARa to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice.23475543Jana A, Modi KK, Roy A, Anderson JA, van Breemen RB, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyUp-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders. J Neuroimmune Pharmacol. 2013 Jun; 8(3):739-55.J Neuroimmune Pharmacol2013-03-09T00:00:002013Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders.25788911Pahan P, Pahan KNeural regeneration researchCan cinnamon bring aroma in Parkinson's disease treatment? Neural Regen Res. 2015 Jan; 10(1):30-2.Neural Regen Res2015-01-01T00:00:002015Can cinnamon bring aroma in Parkinson's disease treatment?10841980Pahan K, Schmid MNeuroscience lettersActivation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis. Neurosci Lett. 2000 Jun 16; 287(1):17-20.Neurosci Lett2000-06-16T00:00:002000Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis.19100623Jana M, Pahan KMolecular immunologyIL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol. 2009 Feb; 46(5):773-83.Mol Immunol2008-12-18T00:00:002008IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.8482375Pahan K, Cofer J, Baliga P, Singh IFEBS lettersIdentification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts. FEBS Lett. 1993 May 10; 322(2):101-4.FEBS Lett1993-05-10T00:00:001993Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts.24419943Ray S, Pahan K, Gachhui R, Chaudhuri J, Mandal AWorld journal of microbiology & biotechnologyStudies on the mercury volatilizing enzymes in nitrogen-fixing Beijerinckia mobilis. World J Microbiol Biotechnol. 1993 Mar; 9(2):184-6.World J Microbiol Biotechnol1993-03-01T00:00:001993Studies on the mercury volatilizing enzymes in nitrogen-fixing Beijerinckia mobilis.19694602Roy A, Pahan KImmunopharmacology and immunotoxicologyGemfibrozil, stretching arms beyond lipid lowering. Immunopharmacol Immunotoxicol. 2009; 31(3):339-51.Immunopharmacol Immunotoxicol2009-01-01T00:00:002009Gemfibrozil, stretching arms beyond lipid lowering.8486724Singh I, Pahan K, Dhaunsi GS, Lazo O, Ozand PThe Journal of biological chemistryPhytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. J Biol Chem. 1993 May 15; 268(14):9972-9.J Biol Chem1993-05-15T00:00:001993Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz.10066820Pahan K, Raymond JR, Singh IThe Journal of biological chemistryInhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. J Biol Chem. 1999 Mar 12; 274(11):7528-36.J Biol Chem1999-03-12T00:00:001999Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells.19587012Brahmachari S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. J Immunol. 2009 Aug 01; 183(3):2045-58.J Immunol2009-07-08T00:00:002009Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide.9575170Pahan K, Sheikh FG, Namboodiri AM, Singh IThe Journal of biological chemistryInhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages. J Biol Chem. 1998 May 15; 273(20):12219-26.J Biol Chem1998-05-15T00:00:001998Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages.23744481Li X, Kroin JS, Kc R, Gibson G, Chen D, Corbett GT, Pahan K, Fayyaz S, Kim JS, van Wijnen AJ, Suh J, Kim SG, Im HJJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchAltered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints. J Bone Miner Res. 2013 Dec; 28(12):2512-22.J Bone Miner Res2013-12-01T00:00:002013Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints.9358238Pahan K, Smith BT, Singh AK, Singh IFree radical biology & medicineCytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress. Free Radic Biol Med. 1997; 23(7):963-71.Free Radic Biol Med1997-01-01T00:00:001997Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress.11551948Jana M, Liu X, Koka S, Ghosh S, Petro TM, Pahan KThe Journal of biological chemistryLigation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells. J Biol Chem. 2001 Nov 30; 276(48):44527-33.J Biol Chem2001-09-10T00:00:002001Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells.25783477Roy A, Mondal S, Kordower JH, Pahan KNeuroscienceAttenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey. Neuroscience. 2015 Aug 27; 302:36-46.Neuroscience2015-03-14T00:00:002015Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey.26621249Ghosh A, Pahan KPharmacological researchPPARa in lysosomal biogenesis: A perspective. 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J Neuroimmune Pharmacol. 2006 Sep; 1(3):212-22.J Neuroimmune Pharmacol2006-05-16T00:00:002006Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine.16046404Dasgupta S, Jana M, Liu X, Pahan KThe Journal of biological chemistryMyelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. J Biol Chem. 2005 Sep 23; 280(38):32609-17.J Biol Chem2005-07-26T00:00:002005Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis.8555680Pahan K, Chaudhuri J, Ghosh D, Gachhui R, Ray S, Mandal ABulletin of environmental contamination and toxicologyEnhanced elimination of HgCl2 from natural water by a broad-spectrum Hg-resistant Bacillus pasteurii strain DR2 in presence of benzene. Bull Environ Contam Toxicol. 1995 Oct; 55(4):554-61.Bull Environ Contam Toxicol1995-10-01T00:00:001995Enhanced elimination of HgCl2 from natural water by a broad-spectrum Hg-resistant Bacillus pasteurii strain DR2 in presence of benzene.20607622Jana A, Pahan KNeuromolecular medicineSphingolipids in multiple sclerosis. Neuromolecular Med. 2010 Dec; 12(4):351-61.Neuromolecular Med2010-07-07T00:00:002010Sphingolipids in multiple sclerosis.23289514Miller NM, Shriver LP, Bodiga VL, Ray A, Basu S, Ahuja R, Jana A, Pahan K, Dittel BNASN neuroLymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death. 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Free Radic Biol Med. 2008 Sep 01; 45(5):686-99.Free Radic Biol Med2008-06-06T00:00:002008Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases.9436612Pahan K, Sheikh FG, Namboodiri AM, Singh IFree radical biology & medicineN-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes. Free Radic Biol Med. 1998 Jan 01; 24(1):39-48.Free Radic Biol Med1998-01-01T00:00:001998N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes.12167619Liu X, Jana M, Dasgupta S, Koka S, He J, Wood C, Pahan KThe Journal of biological chemistryHuman immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. J Biol Chem. 2002 Oct 18; 277(42):39312-9.J Biol Chem2002-08-07T00:00:002002Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia.18981147Jana M, Palencia CA, Pahan KJournal of immunology (Baltimore, Md. : 1950)Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease. J Immunol. 2008 Nov 15; 181(10):7254-62.J Immunol2008-11-15T00:00:002008Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease.8620052Kremser K, Stangl H, Pahan K, Singh IEuropean journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry SocietiesNitric oxide regulates peroxisomal enzyme activities. Eur J Clin Chem Clin Biochem. 1995 Nov; 33(11):763-74.Eur J Clin Chem Clin Biochem1995-11-01T00:00:001995Nitric oxide regulates peroxisomal enzyme activities.22718805Tiniakov R, Pahan K, Scrogin KEAmerican journal of physiology. Regulatory, integrative and comparative physiologySympathetic innervation of the splanchnic region mediates the beneficial hemodynamic effects of 8-OH-DPAT in hemorrhagic shock. Am J Physiol Regul Integr Comp Physiol. 2012 Sep 01; 303(5):R527-38.Am J Physiol Regul Integr Comp Physiol2012-06-20T00:00:002012Sympathetic innervation of the splanchnic region mediates the beneficial hemodynamic effects of 8-OH-DPAT in hemorrhagic shock.19864567Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceSimvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci. 2009 Oct 28; 29(43):13543-56.J Neurosci2009-10-28T00:00:002009Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.12911614Saha RN, Pahan KJournal of neurochemistryTumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia. J Neurochem. 2003 Sep; 86(5):1057-71.J Neurochem2003-09-01T00:00:002003Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia.22723850Roy A, Ghosh A, Jana A, Liu X, Brahmachari S, Gendelman HE, Pahan KPloS oneSodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. PLoS One. 2012; 7(6):e38113.PLoS One2012-06-18T00:00:002012Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease.8167453Pahan K, Ghosh DK, Ray S, Gachhui R, Chaudhuri J, Mandal ABulletin of environmental contamination and toxicologyMercury and organomercurial degrading enzymes in a broad-spectrum Hg-resistant strain of Bacillus pasteurii. Bull Environ Contam Toxicol. 1994 Apr; 52(4):582-9.Bull Environ Contam Toxicol1994-04-01T00:00:001994Mercury and organomercurial degrading enzymes in a broad-spectrum Hg-resistant strain of Bacillus pasteurii.11796758Jana M, Dasgupta S, Liu X, Pahan KJournal of neurochemistryRegulation of tumor necrosis factor-alpha expression by CD40 ligation in BV-2 microglial cells. J Neurochem. 2002 Jan; 80(1):197-206.J Neurochem2002-01-01T00:00:002002Regulation of tumor necrosis factor-alpha expression by CD40 ligation in BV-2 microglial cells.7544821Pahan K, Singh IJournal of lipid researchPhytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes. J Lipid Res. 1995 May; 36(5):986-97.J Lipid Res1995-05-01T00:00:001995Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes.23744073Khasnavis S, Ghosh A, Roy A, Pahan KThe Journal of biological chemistryCastration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. J Biol Chem. 2013 Jul 19; 288(29):20843-20855.J Biol Chem2013-06-06T00:00:002013Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase.2031999Gachhui R, Pahan K, Ray S, Chaudhuri J, Mandal ABulletin of environmental contamination and toxicologyCell free glutathione synthesizing activity of mercury resistant bacteria. Bull Environ Contam Toxicol. 1991 Mar; 46(3):336-42.Bull Environ Contam Toxicol1991-03-01T00:00:001991Cell free glutathione synthesizing activity of mercury resistant bacteria.15509740Jana A, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceHuman immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase. J Neurosci. 2004 Oct 27; 24(43):9531-40.J Neurosci2004-10-27T00:00:002004Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase.17447141Jana M, Jana A, Pal U, Pahan KNeurochemical researchA simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue. Neurochem Res. 2007 Dec; 32(12):2015-22.Neurochem Res2007-04-20T00:00:002007A simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue.24419942Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal AWorld journal of microbiology & biotechnologyHeat sensitivity of mercuric ion and organomercurial degrading enzymes of aquatic, mercury-resistant bacteria. World J Microbiol Biotechnol. 1993 Mar; 9(2):180-3.World J Microbiol Biotechnol1993-03-01T00:00:001993Heat sensitivity of mercuric ion and organomercurial degrading enzymes of aquatic, mercury-resistant bacteria.26916519Roy A, Rangasamy SB, Kundu M, Pahan KScientific reportsBPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease. Sci Rep. 2016 Feb 26; 6:22067.Sci Rep2016-02-26T00:00:002016BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease.20083653Brahmachari S, Pahan KJournal of immunology (Baltimore, Md. : 1950)Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. J Immunol. 2010 Feb 15; 184(4):1799-809.J Immunol2010-01-18T00:00:002010Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide.21252380Roy A, Pahan KThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatryProspects of statins in Parkinson disease. Neuroscientist. 2011 Jun; 17(3):244-55.Neuroscientist2011-01-20T00:00:002011Prospects of statins in Parkinson disease.11110796Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M, Petro TMThe Journal of biological chemistryInduction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells. J Biol Chem. 2001 Mar 16; 276(11):7899-905.J Biol Chem2000-12-07T00:00:002000Induction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells.9527517Gachhui R, Chaudhuri J, Ray S, Pahan K, Mandal AFolia microbiologicaStudies on mercury-detoxicating enzymes from a broad-spectrum mercury-resistant strain of Flavobacterium rigense. Folia Microbiol (Praha). 1997; 42(4):337-43.Folia Microbiol (Praha)1997-01-01T00:00:001997Studies on mercury-detoxicating enzymes from a broad-spectrum mercury-resistant strain of Flavobacterium rigense.7504046Singh I, Pahan K, Singh AK, Barbosa EJournal of lipid researchRefsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes. J Lipid Res. 1993 Oct; 34(10):1755-64.J Lipid Res1993-10-01T00:00:001993Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes.10430507Stanislaus R, Pahan K, Singh AK, Singh INeuroscience lettersAmelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neurosci Lett. 1999 Jul 09; 269(2):71-4.Neurosci Lett1999-07-09T00:00:001999Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin.16740341Saha RN, Pahan KNeurochemistry internationalSignals for the induction of nitric oxide synthase in astrocytes. Neurochem Int. 2006 Jul; 49(2):154-63.Neurochem Int2006-06-05T00:00:002006Signals for the induction of nitric oxide synthase in astrocytes.19342681Mondal S, Roy A, Pahan KJournal of immunology (Baltimore, Md. : 1950)Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2009 Apr 15; 182(8):5013-23.J Immunol2009-04-15T00:00:002009Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis.10820188Pahan K, Liu X, McKinney MJ, Wood C, Sheikh FG, Raymond JRJournal of neurochemistryExpression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kappaB in primary astrocytes. J Neurochem. 2000 Jun; 74(6):2288-95.J Neurochem2000-06-01T00:00:002000Expression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kappaB in primary astrocytes.16167067Saha RN, Pahan KCell death and differentiationHATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ. 2006 Apr; 13(4):539-50.Cell Death Differ2006-04-01T00:00:002006HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis.Authorship 378193Authorship 37871131782056Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyA Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases. J Neuroimmune Pharmacol. 2019 12; 14(4):534-536.J Neuroimmune Pharmacol2019-11-28T00:00:002019A Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases.31797405Patel D, Roy A, Pahan KJournal of neuroscience researchPPARa serves as a new receptor of aspirin for neuroprotection. J Neurosci Res. 2020 04; 98(4):626-631.J Neurosci Res2019-12-03T00:00:002019PPARa serves as a new receptor of aspirin for neuroprotection.PathologyMalubenduJanaMalubendu Jana349337Jana, MalubenduAssistant ProfessorSusantaMondalSusanta Mondal349459Mondal, SusantaAssistant ProfessorLenaAl-HarthiLena Al-Harthi41.87386750000000-87.67102690000000349563Al-Harthi, Lena0000-0003-3915-3904Professor6Assistant Professor4ProfessorAuthorship 38823332151546Rangasamy SB, Ghosh S, Pahan KExperimental neurologyRNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury. Exp Neurol. 2020 06; 328:113279.Exp Neurol2020-03-06T00:00:002020RNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury.D051379Living Beings18816080.701537MiceAuthorship 390556Authorship 39149232315292Patel D, Roy A, Raha S, Kundu M, Gonzalez FJ, Pahan KJCI insightUpregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARa. JCI Insight. 2020 05 21; 5(10).JCI Insight2020-05-21T00:00:002020Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARa.32415419Pahan P, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologySmooth or Risky Revisit of an Old Malaria Drug for COVID-19? J Neuroimmune Pharmacol. 2020 06; 15(2):174-180.J Neuroimmune Pharmacol2020-05-15T00:00:002020Smooth or Risky Revisit of an Old Malaria Drug for COVID-19?Authorship 4022110Authorship 40368432817415Mondal S, Kundu M, Jana M, Roy A, Rangasamy SB, Modi KK, Wallace J, Albalawi YA, Balabanov R, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaIL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21557-21567.Proc Natl Acad Sci U S A2020-08-19T00:00:002020IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE.32889602Raha S, Dutta D, Roy A, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyReduction of Lewy Body Pathology by Oral Cinnamon. J Neuroimmune Pharmacol. 2021 09; 16(3):592-608.J Neuroimmune Pharmacol2020-09-05T00:00:002020Reduction of Lewy Body Pathology by Oral Cinnamon.Authorship 404656Authorship 405452Authorship 408905Authorship 41292233294884Pahan S, Pahan KJournal of clinical & experimental immunologyCan cinnamon spice down autoimmune diseases? J Clin Exp Immunol. 2020; 5(6):252-258.J Clin Exp Immunol2020-11-23T00:00:002020Can cinnamon spice down autoimmune diseases?33405098Mukherjee S, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyIs COVID-19 Gender-sensitive? J Neuroimmune Pharmacol. 2021 03; 16(1):38-47.J Neuroimmune Pharmacol2021-01-06T00:00:002021Is COVID-19 Gender-sensitive?33426604Paidi RK, Jana M, Mishra RK, Dutta D, Raha S, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyACE-2-interacting Domain of SARS-CoV-2 (AIDS) Peptide Suppresses Inflammation to Reduce Fever and Protect Lungs and Heart in Mice: Implications for COVID-19 Therapy. J Neuroimmune Pharmacol. 2021 03; 16(1):59-70.J Neuroimmune Pharmacol2021-01-11T00:00:002021ACE-2-interacting Domain of SARS-CoV-2 (AIDS) Peptide Suppresses Inflammation to Reduce Fever and Protect Lungs and Heart in Mice: Implications for COVID-19 Therapy.33514677Gottschalk CG, Jana M, Roy A, Patel DR, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceGemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARa-Dependent Astrocytic GDNF Pathway. J Neurosci. 2021 03 10; 41(10):2287-2300.J Neurosci2021-01-29T00:00:002021Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARa-Dependent Astrocytic GDNF Pathway.Neurological SciencesRush University, Rush Medical CollegeDavidBennettDavid A. Bennett41.87328300000000-87.66936330000000349004Bennett, DavidProfessorJeffreyKordowerJeffrey Kordower41.87386750000000-87.67102690000000349008Kordower, JeffreyProfessorAliKeshavarzianAli Keshavarzian41.87386750000000-87.67102690000000349021Keshavarzian, AliProfessorJulieSchneiderJulie A. Schneider41.87328300000000-87.66936330000000349026Schneider, JulieProfessorAuthorship 416296Authorship 41661433636386Dutta D, Majumder M, Paidi RK, Pahan KNeurobiology of diseaseAlleviation of Huntington pathology in mice by oral administration of food additive glyceryl tribenzoate. Neurobiol Dis. 2021 06; 153:105318.Neurobiol Dis2021-02-24T00:00:002021Alleviation of Huntington pathology in mice by oral administration of food additive glyceryl tribenzoate.34113786Rangasamy SB, Dasarathi S, Nutakki A, Mukherjee S, Nellivalasa R, Pahan KJournal of Alzheimer's disease reportsStimulation of Dopamine Production by Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive. J Alzheimers Dis Rep. 2021 Apr 23; 5(1):295-310.J Alzheimers Dis Rep2021-04-23T00:00:002021Stimulation of Dopamine Production by Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive.Authorship 42903634508096Dutta D, Jana M, Majumder M, Mondal S, Roy A, Pahan KNature communicationsSelective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo. Nat Commun. 2021 09 10; 12(1):5382.Nat Commun2021-09-10T00:00:002021Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo.Authorship 437845Authorship 441774Authorship 443606Authorship 444365Authorship 445375Authorship 445384Authorship 452237Authorship 45489334632302Chakrabarti S, Prorok T, Roy A, Patel D, Dasarathi S, Pahan KJournal of Alzheimer's disease reportsUpregulation of IL-1 Receptor Antagonist by Aspirin in Glial Cells via Peroxisome Proliferator-Activated Receptor-Alpha. J Alzheimers Dis Rep. 2021; 5(1):647-661.J Alzheimers Dis Rep2021-08-10T00:00:002021Upregulation of IL-1 Receptor Antagonist by Aspirin in Glial Cells via Peroxisome Proliferator-Activated Receptor-Alpha.34645689Paidi RK, Jana M, Mishra RK, Dutta D, Pahan KJournal of immunology (Baltimore, Md. : 1950)Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses. J Immunol. 2021 11 15; 207(10):2521-2533.J Immunol2021-10-13T00:00:002021Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses.34677731Paidi RK, Jana M, Raha S, McKay M, Sheinin M, Mishra RK, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyEugenol, a Component of Holy Basil (Tulsi) and Common Spice Clove, Inhibits the Interaction Between SARS-CoV-2 Spike S1 and ACE2 to Induce Therapeutic Responses. J Neuroimmune Pharmacol. 2021 12; 16(4):743-755.J Neuroimmune Pharmacol2021-10-22T00:00:002021Eugenol, a Component of Holy Basil (Tulsi) and Common Spice Clove, Inhibits the Interaction Between SARS-CoV-2 Spike S1 and ACE2 to Induce Therapeutic Responses.34699252Raha S, Ghosh A, Dutta D, Patel DR, Pahan KScience signalingActivation of PPARa enhances astroglial uptake and degradation of ?-amyloid. Sci Signal. 2021 Oct 26; 14(706):eabg4747.Sci Signal2021-10-26T00:00:002021Activation of PPARa enhances astroglial uptake and degradation of ?-amyloid.34723288Pahan S, Dasarathi S, Pahan KJournal of clinical & experimental immunologyGlyceryl tribenzoate: A food additive with unique properties to be a substitute for cinnamon. J Clin Exp Immunol. 2021; 6(5):367-372.J Clin Exp Immunol2021-10-20T00:00:002021Glyceryl tribenzoate: A food additive with unique properties to be a substitute for cinnamon.34744082Roy A, Kundu M, Chakrabarti S, Patel DR, Pahan KJournal of Alzheimer's disease : JADOleamide, a Sleep-Inducing Supplement, Upregulates Doublecortin in Hippocampal Progenitor Cells via PPARa. J Alzheimers Dis. 2021; 84(4):1747-1762.J Alzheimers Dis2021-01-01T00:00:002021Oleamide, a Sleep-Inducing Supplement, Upregulates Doublecortin in Hippocampal Progenitor Cells via PPARa.35008615Rangasamy SB, Raha S, Dasarathy S, Pahan KInternational journal of molecular sciencesSodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury. Int J Mol Sci. 2021 Dec 24; 23(1).Int J Mol Sci2021-12-24T00:00:002021Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury.35053375Kundu M, Raha S, Roy A, Pahan KCellsRegression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2).Cells2022-01-13T00:00:002022Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer.Internal Medicine, Division of Digestive Diseases and NutritionD047493Chemicals & Drugs3300.921933PPAR alphatrue1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Assistant ProfessorAssistant ProfessorAuthorship 249303Authorship 249351Authorship 250522Authorship 250731Authorship 250852Authorship 253711Authorship 256305Authorship 258075Authorship 259718Authorship 265694Authorship 266815Authorship 268433Authorship 26877423275862Mondal S, Brahmachari S, Pahan KJournal of clinical & cellular immunologyRegulation of encephalitogenicity of neuroantigen-primed T cells by nitric oxide: Implications for multiple sclerosis. J Clin Cell Immunol. 2012 Jul 16; 3(3):124.J Clin Cell Immunol2012-07-16T00:00:002012Regulation of encephalitogenicity of neuroantigen-primed T cells by nitric oxide: Implications for multiple sclerosis.23336087Pahan K, Mondal SJournal of clinical & cellular immunologyCrosstalk between Nitric Oxide and T helper cells. J Clin Cell Immunol. 2012 Nov 28; 3(4).J Clin Cell Immunol2012-11-28T00:00:002012Crosstalk between Nitric Oxide and T helper cells.24273691Jana M, Pahan KJournal of clinical & cellular immunologyDown-regulation of Myelin Gene Expression in Human Oligodendrocytes by Nitric Oxide: Implications for Demyelination in Multiple Sclerosis. J Clin Cell Immunol. 2013 Jul 31; 4.J Clin Cell Immunol2013-07-31T00:00:002013Down-regulation of Myelin Gene Expression in Human Oligodendrocytes by Nitric Oxide: Implications for Demyelination in Multiple Sclerosis.24478934Pahan KJournal of clinical & cellular immunologyMultiple Sclerosis and Experimental Allergic Encephalomyelitis. J Clin Cell Immunol. 2013 Sep 23; 4.J Clin Cell Immunol2013-09-23T00:00:002013Multiple Sclerosis and Experimental Allergic Encephalomyelitis.24575330Roy A, Pahan KJournal of clinical & cellular immunologyMyelin Basic Protein-primed T Helper 2 Cells Suppress Microglial Activation via AlphaVBeta3 Integrin: Implications for Multiple Sclerosis. J Clin Cell Immunol. 2013 Aug 12; 7:158.J Clin Cell Immunol2013-08-12T00:00:002013Myelin Basic Protein-primed T Helper 2 Cells Suppress Microglial Activation via AlphaVBeta3 Integrin: Implications for Multiple Sclerosis.26380380Pahan KJournal of multiple sclerosisProspects of Cinnamon in Multiple Sclerosis. J Mult Scler (Foster City). 2015; 2(3):1000149.J Mult Scler (Foster City)2015-01-01T00:00:002015Prospects of Cinnamon in Multiple Sclerosis.27342118Modi KK, Rangasamy SB, Dasarathi S, Roy A, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyCinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement. J Neuroimmune Pharmacol. 2016 12; 11(4):693-707.J Neuroimmune Pharmacol2016-06-24T00:00:002016Cinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement.27605008Kundu M, Mondal S, Roy A, Martinson JL, Pahan KJournal of immunology (Baltimore, Md. : 1950)Sodium Benzoate, a Food Additive and a Metabolite of Cinnamon, Enriches Regulatory T Cells via STAT6-Mediated Upregulation of TGF-?. J Immunol. 2016 10 15; 197(8):3099-3110.J Immunol2016-09-07T00:00:002016Sodium Benzoate, a Food Additive and a Metabolite of Cinnamon, Enriches Regulatory T Cells via STAT6-Mediated Upregulation of TGF-?.27748752Roy A, Kundu M, Jana M, Mishra RK, Yung Y, Luan CH, Gonzalez FJ, Pahan KNature chemical biologyIdentification and characterization of PPARa ligands in the hippocampus. Nat Chem Biol. 2016 Dec; 12(12):1075-1083.Nat Chem Biol2016-10-17T00:00:002016Identification and characterization of PPARa ligands in the hippocampus.28199020Ghosh A, Rangasamy SB, Modi KK, Pahan KJournal of neurochemistryGemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis. J Neurochem. 2017 05; 141(3):423-435.J Neurochem2017-04-03T00:00:002017Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis.28271325Mondal S, Rangasamy SB, Ghosh S, Watson RL, Pahan KNeurochemical researchNebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy. Neurochem Res. 2017 May; 42(5):1555-1570.Neurochem Res2017-03-07T00:00:002017Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy.28367355Mondal S, Dasarathi S, Pahan KJournal of clinical & cellular immunologyGlyceryl Tribenzoate: A Flavoring Ingredient, Inhibits the Adoptive Transfer of Experimental Allergic Encephalomyelitis via TGF-?: Implications for Multiple Sclerosis Therapy. J Clin Cell Immunol. 2017 Feb; 8(1).J Clin Cell Immunol2017-01-31T00:00:002017Glyceryl Tribenzoate: A Flavoring Ingredient, Inhibits the Adoptive Transfer of Experimental Allergic Encephalomyelitis via TGF-?: Implications for Multiple Sclerosis Therapy.28446566Chandra G, Roy A, Rangasamy SB, Pahan KJournal of immunology (Baltimore, Md. : 1950)Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson's Disease. J Immunol. 2017 06 01; 198(11):4312-4326.J Immunol2017-04-26T00:00:002017Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson's Disease.true1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant ProfessorJennilleeWallaceJennillee Wallace350107Wallace, JennilleeAssistant ProfessorAuthorship 284964Authorship 285615Authorship 29184328623936Kim K, Kleinman HK, Lee HJ, Pahan KOrphanet journal of rare diseasesSafety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders. Orphanet J Rare Dis. 2017 06 17; 12(1):113.Orphanet J Rare Dis2017-06-17T00:00:002017Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders.28654697Modi KK, Jana A, Ghosh S, Watson R, Pahan KPloS oneCorrection: A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease. PLoS One. 2017; 12(6):e0180602.PLoS One2017-06-27T00:00:002017Correction: A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease.29073075Kundu M, Roy A, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaSelective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12-IFN-?. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11482-11487.Proc Natl Acad Sci U S A2017-10-09T00:00:002017Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12-IFN-?.Authorship 29312329143164Jana M, Ghosh S, Pahan KNeurochemical researchUpregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018 Feb; 43(2):407-419.Neurochem Res2017-11-15T00:00:002017Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis.true1ProfessorProfessorMicrobial Pathogens and ImmunityAuthorship 29395729188424Chandra G, Kundu M, Rangasamy SB, Dasarathy S, Ghosh S, Watson R, Pahan KJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune PharmacologyIncrease in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1a. J Neuroimmune Pharmacol. 2018 06; 13(2):143-162.J Neuroimmune Pharmacol2017-11-29T00:00:002017Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1a.Authorship 458483Authorship 458504Authorship 466987Authorship 463314Authorship 458214Authorship 475574Authorship 474937Authorship 480855Authorship 485754Authorship 476217Authorship 468306Authorship 476973Authorship 46404737314416Sheinin M, Mondal S, Roy A, Gorai S, Rangasamy SB, Poddar J, Pahan KJournal of immunology (Baltimore, Md. : 1950)Suppression of Experimental Autoimmune Encephalomyelitis in Mice by ?-Hydroxy ?-Methylbutyrate, a Body-Building Supplement in Humans. J Immunol. 2023 07 15; 211(2):187-198.J Immunol2023-07-15T00:00:002023Suppression of Experimental Autoimmune Encephalomyelitis in Mice by ?-Hydroxy ?-Methylbutyrate, a Body-Building Supplement in Humans.36902085Jana M, Dasarathy S, Ghosh S, Pahan KInternational journal of molecular sciencesUpregulation of DJ-1 in Dopaminergic Neurons by a Physically-Modified Saline: Implications for Parkinson's Disease. Int J Mol Sci. 2023 Feb 28; 24(5).Int J Mol Sci2023-02-28T00:00:002023Upregulation of DJ-1 in Dopaminergic Neurons by a Physically-Modified Saline: Implications for Parkinson's Disease.36428739Sheinin M, Jeong B, Paidi RK, Pahan KCancersRegression of Lung Cancer in Mice by Intranasal Administration of SARS-CoV-2 Spike S1. Cancers (Basel). 2022 Nov 17; 14(22).Cancers (Basel)2022-11-17T00:00:002022Regression of Lung Cancer in Mice by Intranasal Administration of SARS-CoV-2 Spike S1.37437568Paidi RK, Raha S, Roy A, Pahan KCell reportsMuscle-building supplement ?-hydroxy ?-methylbutyrate binds to PPARa to improve hippocampal functions in mice. Cell Rep. 2023 07 25; 42(7):112717.Cell Rep2023-07-11T00:00:002023Muscle-building supplement ?-hydroxy ?-methylbutyrate binds to PPARa to improve hippocampal functions in mice.37885917Chakrabarti S, Gorai S, Pahan KNeuroImmune pharmacology and therapeuticsA simple protocol for isolating microglia from adult mouse brain. NeuroImmune Pharm Ther. 2023 Sep; 2(3):293-300.NeuroImmune Pharm Ther2023-08-02T00:00:002023A simple protocol for isolating microglia from adult mouse brain.37552543Dutta D, Jana M, Paidi RK, Majumder M, Raha S, Dasarathy S, Pahan KThe Journal of clinical investigationTau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models. J Clin Invest. 2023 09 15; 133(18).J Clin Invest2023-09-15T00:00:002023Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models.35830804Dutta D, Paidi RK, Raha S, Roy A, Chandra S, Pahan KCell reportsTreadmill exercise reduces a-synuclein spreading via PPARa. Cell Rep. 2022 07 12; 40(2):111058.Cell Rep2022-07-12T00:00:002022Treadmill exercise reduces a-synuclein spreading via PPARa.36682514Rangasamy SB, Jana M, Dasarathi S, Kundu M, Pahan KBrain, behavior, and immunityTreadmill workout activates PPARa in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease. Brain Behav Immun. 2023 03; 109:204-218.Brain Behav Immun2023-01-19T00:00:002023Treadmill workout activates PPARa in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease.36697260Jana M, Dutta D, Poddar J, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceActivation of PPARa Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis. J Neurosci. 2023 03 08; 43(10):1814-1829.J Neurosci2023-01-25T00:00:002023Activation of PPARa Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis.36720111Rangasamy SB, Dutta D, Mondal S, Majumder M, Dasarathy S, Chandra G, Pahan KNeuroImmune pharmacology and therapeuticsProtection of dopaminergic neurons in hemiparkinsonian monkeys by flavouring ingredient glyceryl tribenzoate. NeuroImmune Pharm Ther. 2022 Mar 25; 1(1):7-22.NeuroImmune Pharm Ther2022-03-25T00:00:002022Protection of dopaminergic neurons in hemiparkinsonian monkeys by flavouring ingredient glyceryl tribenzoate.36768402Rangasamy SB, Poddar J, Pahan KInternational journal of molecular sciencesProtection of Mice from Controlled Cortical Impact Injury by Food Additive Glyceryl Tribenzoate. Int J Mol Sci. 2023 Jan 20; 24(3).Int J Mol Sci2023-01-20T00:00:002023Protection of Mice from Controlled Cortical Impact Injury by Food Additive Glyceryl Tribenzoate.36848307Pahan S, Raha S, Dasarathi S, Pahan KJournal of clinical & experimental immunologyCinnamein Inhibits the Induction of Nitric Oxide and Proinflammatory Cytokines in Macrophages, Microglia and Astrocytes. J Clin Exp Immunol. 2023; 8(1):520-529.J Clin Exp Immunol2023-01-31T00:00:002023Cinnamein Inhibits the Induction of Nitric Oxide and Proinflammatory Cytokines in Macrophages, Microglia and Astrocytes.37144841Paidi RK, Jana M, Raha S, Mishra RK, Jeong B, Sheinin M, Pahan KJournal of immunology (Baltimore, Md. : 1950)Prenol, but Not Vitamin C, of Fruit Binds to SARS-CoV-2 Spike S1 to Inhibit Viral Entry: Implications for COVID-19. J Immunol. 2023 06 15; 210(12):1938-1949.J Immunol2023-06-15T00:00:002023Prenol, but Not Vitamin C, of Fruit Binds to SARS-CoV-2 Spike S1 to Inhibit Viral Entry: Implications for COVID-19.Authorship 48616438056248Jana M, Mondal S, Jana A, Pahan KCytokineInduction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis. Cytokine. 2024 Feb; 174:156457.Cytokine2023-12-05T00:00:002023Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis.D001253Anatomy351220.884112AstrocytesAuthorship 487963Authorship 48822438132111Raha S, Dutta D, Paidi RK, Pahan KCellsLipid-Lowering Drug Gemfibrozil Protects Mice from Tay-Sachs Disease via Peroxisome Proliferator-Activated Receptor a. Cells. 2023 Dec 08; 12(24).Cells2023-12-08T00:00:002023Lipid-Lowering Drug Gemfibrozil Protects Mice from Tay-Sachs Disease via Peroxisome Proliferator-Activated Receptor a.38136341Sheinin M, Mondal S, Pahan KCancersNeutralization of p40 Homodimer and p40 Monomer Leads to Tumor Regression in Patient-Derived Xenograft Mice with Pancreatic Cancer. Cancers (Basel). 2023 Dec 11; 15(24).Cancers (Basel)2023-12-11T00:00:002023Neutralization of p40 Homodimer and p40 Monomer Leads to Tumor Regression in Patient-Derived Xenograft Mice with Pancreatic Cancer.Authorship 31583529611013Mondal S, Rangasamy SB, Ghosh S, Watson RL, Pahan KNeurochemical researchCorrection to: Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy. Neurochem Res. 2018 05; 43(5):1136-1139.Neurochem Res2018-05-01T00:00:002018Correction to: Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy.Authorship 31907429732971Chakrabarti S, Jana M, Roy A, Pahan KCurrent Alzheimer researchUpregulation of Suppressor of Cytokine Signaling 3 in Microglia by Cinnamic Acid. Curr Alzheimer Res. 2018; 15(10):894-904.Curr Alzheimer Res2018-01-01T00:00:002018Upregulation of Suppressor of Cytokine Signaling 3 in Microglia by Cinnamic Acid.Authorship 3229224Authorship 324233Authorship 3245213Authorship 32483729906573Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DANeurobiology of learning and memoryStore depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiol Learn Mem. 2018 10; 154:141-157.Neurobiol Learn Mem2018-06-12T00:00:002018Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.29967008Chandra S, Jana M, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceAspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARa. J Neurosci. 2018 07 25; 38(30):6682-6699.J Neurosci2018-07-02T00:00:002018Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARa.29990310Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson EJ, Mishra RK, Luan CH, Bennett DA, Pahan KThe Journal of clinical investigationSelective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology. J Clin Invest. 2018 10 01; 128(10):4297-4312.J Clin Invest2018-07-10T00:00:002018Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology.30012602Patel D, Roy A, Kundu M, Jana M, Luan CH, Gonzalez FJ, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaAspirin binds to PPARa to stimulate hippocampal plasticity and protect memory. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):E7408-E7417.Proc Natl Acad Sci U S A2018-07-16T00:00:002018Aspirin binds to PPARa to stimulate hippocampal plasticity and protect memory.