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Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy.
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Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy.
Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy. J Clin Invest. 2020 01 02; 130(1):451-465.
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PubMed
subject areas
Animals
Carcinoma, Pancreatic Ductal
CD8-Positive T-Lymphocytes
Cell Line, Tumor
Diazooxonorleucine
Female
Hexosamines
Humans
Mice
Mice, Nude
Neoplasm Metastasis
Neoplasm Proteins
Pancreatic Neoplasms
Programmed Cell Death 1 Receptor
Xenograft Model Antitumor Assays
authors with profiles
Vineet Gupta