D001665Chemicals & DrugsG02.111.570.12040730.981765Binding SitesFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31230402S?ndergaard MT, Liu Y, Brohus M, Guo W, Nani A, Carvajal C, Fill M, Overgaard MT, Chen SRWThe FEBS journalDiminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.FEBS J2019-07-12T00:00:002019Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations.0.5135660.0116340research area of0.2059250.0082349577subject area for31266820Polat OK, Uno M, Maruyama T, Tran HN, Imamura K, Wong CF, Sakaguchi R, Ariyoshi M, Itsuki K, Ichikawa J, Morii T, Shirakawa M, Inoue R, Asanuma K, Reiser J, Tochio H, Mori Y, Mori MXJournal of the American Society of Nephrology : JASNContribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 09; 30(9):1587-1603.J Am Soc Nephrol2019-07-02T00:00:002019Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes.true1Assistant ProfessorAssistant ProfessorThomasDeCourseyThomas DeCoursey41.87432800000000-87.67059170000000349235DeCoursey, ThomasProfessorBobEisenbergBob Eisenberg41.87432800000000-87.67059170000000349256Eisenberg, Bob0000-0002-4860-5434ProfessorDirkGillespieDirk Gillespie41.87432800000000-87.67059170000000349292Gillespie, DirkProfessorChundoOhChundo Oh349474Oh, ChundoAssistant ProfessorLenaAl-HarthiLena Al-Harthi41.87386750000000-87.67102690000000349563Al-Harthi, Lena0000-0003-3915-3904Professor6Assistant Professor4Professor32420736Goldberg JA, Nguyen H, Kumar V, Spencer EJ, Hoyer D, Marshall EK, Cmolik A, O'Shea M, Marshall SH, Hujer AM, Hujer KM, Rudin SD, Domitrovic TN, Bethel CR, Papp-Wallace KM, Logan LK, Perez F, Jacobs MR, van Duin D, Kreiswirth BM, Bonomo RA, Plummer MS, van den Akker FJournal of medicinal chemistryA ?-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli. J Med Chem. 2020 06 11; 63(11):5990-6002.J Med Chem2020-06-02T00:00:002020A ?-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.32902579Cherny VV, Musset B, Morgan D, Thomas S, Smith SME, DeCoursey TEThe Journal of general physiologyEngineered high-affinity zinc binding site reveals gating configurations of a human proton channel. J Gen Physiol. 2020 10 05; 152(10).J Gen Physiol2020-10-05T00:00:002020Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel.Orthopedic SurgeryRush University, Rush Medical College34111951Yin L, Zahradnikova A, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqu?s-Sul? E, Aguilar-S?nchez Y, Fern?ndez-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, ?lvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, G?mez AMCirculation researchImpaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52.Circ Res2021-06-11T00:00:002021Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorPhysiology and Biophysicstrue1ProfessorProfessorMicrobial Pathogens and Immunity