D016859Chemicals & DrugsD27.505.519.389.4803130.995349Lipoxygenase InhibitorsFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson0.4936120.1446933research area of0.2402780.035517413subject area for10232612Hong SH, Avis I, Vos MD, Mart?nez A, Treston AM, Mulshine JLCancer researchRelationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors. Cancer Res. 1999 May 01; 59(9):2223-8.Cancer Res1999-05-01T00:00:001999Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.PhilipBonomiPhilip Bonomi349183Bonomi, PhilipProfessor4Professortrue1ProfessorProfessor10628326Anderson KM, Alrefai WA, Bonomi P, Dudeja P, Ou D, Anderson C, Harris JEAnticancer researchAltered oncogene, tumor suppressor and cell-cycle gene expression in PANC-1 cells cultured with the pleiotrophic 5-lipoxygenase inhibitor, MK886, assessed with a gene chip. Anticancer Res. 1999 Sep-Oct; 19(5B):3873-87.Anticancer Res1999-09-01T00:00:001999Altered oncogene, tumor suppressor and cell-cycle gene expression in PANC-1 cells cultured with the pleiotrophic 5-lipoxygenase inhibitor, MK886, assessed with a gene chip.11311496Ou D, Bonomi P, Jao W, Jadko S, Harris JE, Anderson KMCancer lettersThe mode of cell death in H-358 lung cancer cells cultured with inhibitors of 5-lipoxygenase or the free radical spin trap, NTBN. Cancer Lett. 2001 May 26; 166(2):223-31.Cancer Lett2001-05-26T00:00:002001The mode of cell death in H-358 lung cancer cells cultured with inhibitors of 5-lipoxygenase or the free radical spin trap, NTBN.12664625Anderson KM, Alrefai W, Anderson C, Bonomi P, Harris JAdvances in experimental medicine and biologyMK 886 functions as a radiomimetic agent: genomic responses related to oxidative stress, the cell cycle, proliferation and programmed cell death in Panc-1 cells. Adv Exp Med Biol. 2002; 507:451-6.Adv Exp Med Biol2002-01-01T00:00:002002MK 886 functions as a radiomimetic agent: genomic responses related to oxidative stress, the cell cycle, proliferation and programmed cell death in Panc-1 cells.12968063Anderson KM, Alrefai W, Bonomi P, Seed TM, Dudeja P, Hu Y, Harris JEExperimental biology and medicine (Maywood, N.J.)Caspase-dependent and -independent panc-1 cell death due to actinomycin D and MK 886 are additive but increase clonogenic survival. Exp Biol Med (Maywood). 2003 Sep; 228(8):915-25.Exp Biol Med (Maywood)2003-09-01T00:00:002003Caspase-dependent and -independent panc-1 cell death due to actinomycin D and MK 886 are additive but increase clonogenic survival.Internal MedicineRush University, Rush Medical CollegeAliKeshavarzianAli Keshavarzian41.87386750000000-87.67102690000000349021Keshavarzian, AliProfessorJamesMulshineJames L. Mulshine41.87328300000000-87.66936330000000349025Mulshine, James0000-0002-4648-9177ProfessorInternal Medicine, Division of Digestive Diseases and NutritionInternal Medicine, Division of Hematology/Oncology/Cell Therapytrue1ProfessorProfessortrue1ProfessorProfessor