D059865DisordersG04.434670.997314Endoplasmic Reticulum StressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson30352046Jo S, Fonseca TL, Bocco BMLC, Fernandes GW, McAninch EA, Bolin AP, Da Concei??o RR, Werneck-de-Castro JP, Ignacio DL, Egri P, N?meth D, Fekete C, Bernardi MM, Leitch VD, Mannan NS, Curry KF, Butterfield NC, Bassett JHD, Williams GR, Gereben B, Ribeiro MO, Bianco ACThe Journal of clinical investigationType 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain. J Clin Invest. 2019 01 02; 129(1):230-245.J Clin Invest2018-12-03T00:00:002018Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.0.2134790.03298876research area of0.7011270.132319subject area for30755605Dauer P, Sharma NS, Gupta VK, Durden B, Hadad R, Banerjee S, Dudeja V, Saluja A, Banerjee SCell death & diseaseER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness". Cell Death Dis. 2019 02 12; 10(2):132.Cell Death Dis2019-02-12T00:00:002019ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness".25754093Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann BNature communicationsDefective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015 Mar 10; 6:6496.Nat Commun2015-03-10T00:00:002015Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.true1ProfessorProfessorPediatricsSusanaChubinskayaSusanna Chubinskaya349101Chubinskaya, SusanaProfessorMehmetAltintasMehmet Altintas349147Altintas, MehmetAssociate ProfessorInternal Medicine, Division of EndocrinologyChangli (David)WeiChangli (David) Wei349720Wei, Changli (David)Associate Professor6Assistant Professor5Associate Professor4Professor22053000Arrojo E Drigo R, Fonseca TL, Castillo M, Salathe M, Simovic G, Moh?csik P, Gereben B, Bianco ACMolecular endocrinology (Baltimore, Md.)Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis. Mol Endocrinol. 2011 Dec; 25(12):2065-75.Mol Endocrinol2011-11-03T00:00:002011Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.Rush University, Rush Medical CollegeVineetGuptaVineet Gupta41.87386750000000-87.67102690000000349018Gupta, VineetAssociate Professortrue1Assistant ProfessorAssistant ProfessorElizabethMcAninchElizabeth A. McAninch349951McAninch, ElizabethAssistant Professortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate ProfessorInternal Medicine, Division of Nephrology29892818Bianco AC, da Concei??o RRMethods in molecular biology (Clifton, N.J.)The Deiodinase Trio and Thyroid Hormone Signaling. Methods Mol Biol. 2018; 1801:67-83.Methods Mol Biol2018-01-01T00:00:002018The Deiodinase Trio and Thyroid Hormone Signaling.