Profiles

Keywords
Last Name
Institution

Homogentisate 1,2-Dioxygenase

"Homogentisate 1,2-Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of TYROSINE. Deficiency in the enzyme causes ALKAPTONURIA, an autosomal recessive disorder, characterized by homogentisic aciduria, OCHRONOSIS and ARTHRITIS. This enzyme was formerly characterized as EC 1.13.1.5 and EC 1.99.2.5.


expand / collapse publications
This graph shows the total number of publications written about "Homogentisate 1,2-Dioxygenase" by people in this website by year, and whether "Homogentisate 1,2-Dioxygenase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
_