 Steroid 21-Hydroxylase
"Steroid 21-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013255
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| MeSH Number(s) |
D08.244.453.915.760 D08.811.682.690.708.170.915.760 D08.811.682.690.708.783.760 D12.776.422.220.453.915.760
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| Concept/Terms |
Steroid 21-Hydroxylase- Steroid 21-Hydroxylase
- Steroid 21 Hydroxylase
- Cytochrome P-450 21-Hydroxylase
- Cytochrome P 450 21 Hydroxylase
- Cytochrome P-450 c21
- Cytochrome P 450 c21
- P-450 c21, Cytochrome
- Steroid-21-Hydroxylase
- Cytochrome P-450(c-21)
- Cytochrome P450c21
- Progesterone 21-Hydroxylase
- Progesterone 21 Hydroxylase
- Steroid 21-Monooxygenase
- Steroid 21 Monooxygenase
- 21-Hydroxylase
- 21 Hydroxylase
- Cytochrome P-450 CYP21
- Cytochrome P 450 CYP21
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Below are MeSH descriptors whose meaning is more general than "Steroid 21-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 21-Hydroxylase".
This graph shows the total number of publications written about "Steroid 21-Hydroxylase" by people in this website by year, and whether "Steroid 21-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 |
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Below are the most recent publications written about "Steroid 21-Hydroxylase" by people in Profiles.
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Levine LS, Dupont B, Lorenzen F, Pang S, Pollack M, Oberfield S, Kohn B, Lerner A, Cacciari E, Mantero F, Cassio A, Scaroni C, Chiumello G, Rondanini GF, Gargantini L, Giovannelli G, Virdis R, Bartolotta E, Migliori C, Pintor C, Tato L, Barboni F, New MI. Cryptic 21-hydroxylase deficiency in families of patients with classical congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1980 Dec; 51(6):1316-24.
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