 Leiomyosarcoma
"Leiomyosarcoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
| Descriptor ID |
D007890
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| MeSH Number(s) |
C04.557.450.590.455 C04.557.450.795.455
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| Concept/Terms |
Leiomyosarcoma, Epithelioid- Leiomyosarcoma, Epithelioid
- Epithelioid Leiomyosarcoma
- Epithelioid Leiomyosarcomas
- Leiomyosarcomas, Epithelioid
Leiomyosarcoma, Myxoid- Leiomyosarcoma, Myxoid
- Leiomyosarcomas, Myxoid
- Myxoid Leiomyosarcoma
- Myxoid Leiomyosarcomas
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Below are MeSH descriptors whose meaning is more general than "Leiomyosarcoma".
Below are MeSH descriptors whose meaning is more specific than "Leiomyosarcoma".
This graph shows the total number of publications written about "Leiomyosarcoma" by people in this website by year, and whether "Leiomyosarcoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 3 | 1 | 4 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leiomyosarcoma" by people in Profiles.
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Jones RL, Maki RG, Patel SR, Wang G, McGowan TA, Shalaby WS, Knoblauch RE, von Mehren M, Demetri GD. Safety and efficacy of trabectedin when administered in the inpatient versus outpatient setting: Clinical considerations for outpatient administration of trabectedin. Cancer. 2019 Dec 15; 125(24):4435-4441.
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Jones RL, Le Cesne A, Ibrahim T, Garcia Del Muro X, Menge F. Preserving quality of life as a key treatment goal in advanced soft tissue sarcomas. Expert Rev Anticancer Ther. 2018 12; 18(12):1241-1248.
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Kolson Kokohaare E, Strauss DC, Jones RL, Thway K. Endometrial Stromal Sarcoma With Hyalinizing Giant Rosettes, Mimicking Low-Grade Fibromyxoid Sarcoma. Int J Surg Pathol. 2018 Sep; 26(6):525-527.
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Schneider N, Strauss DC, Smith MJ, Miah AB, Zaidi S, Benson C, van Houdt WJ, Jones RL, Hayes AJ, Fisher C, Thway K. The Adequacy of Core Biopsy in the Assessment of Smooth Muscle Neoplasms of Soft Tissues: Implications for Treatment and Prognosis. Am J Surg Pathol. 2017 Jul; 41(7):923-931.
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Setola E, Noujaim J, Benson C, Chawla S, Palmerini E, Jones RL. Eribulin in advanced liposarcoma and leiomyosarcoma. Expert Rev Anticancer Ther. 2017 08; 17(8):717-723.
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Hensley ML, Patel SR, von Mehren M, Ganjoo K, Jones RL, Staddon A, Rushing D, Milhem M, Monk B, Wang G, McCarthy S, Knoblauch RE, Parekh TV, Maki RG, Demetri GD. Efficacy and safety of trabectedin or dacarbazine in patients with advanced uterine leiomyosarcoma after failure of anthracycline-based chemotherapy: Subgroup analysis of a phase 3, randomized clinical trial. Gynecol Oncol. 2017 09; 146(3):531-537.
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Ikemura K, Lin DM, Martyn CP, Park JW, Seder CW, Gattuso P. Endobronchial Metastasis from Extrapulmonary Neoplasms: Analysis of Clinicopathologic Features and Cytological Evaluation by Bronchial Brushing. Lung. 2017 10; 195(5):595-599.
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Thway K, Robertson D, Jones RL, Selfe J, Shipley J, Fisher C, Isacke CM. Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells. Br J Cancer. 2016 08 09; 115(4):473-9.
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Demetri GD, von Mehren M, Jones RL, Hensley ML, Schuetze SM, Staddon A, Milhem M, Elias A, Ganjoo K, Tawbi H, Van Tine BA, Spira A, Dean A, Khokhar NZ, Park YC, Knoblauch RE, Parekh TV, Maki RG, Patel SR. Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial. J Clin Oncol. 2016 Mar 10; 34(8):786-93.
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Noujaim J, van der Graaf WT, Jones RL. Redefining the standard of care in metastatic leiomyosarcoma. Lancet Oncol. 2015 Apr; 16(4):360-2.
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