 Leiomyosarcoma
"Leiomyosarcoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
| Descriptor ID |
D007890
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| MeSH Number(s) |
C04.557.450.590.455 C04.557.450.795.455
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| Concept/Terms |
Leiomyosarcoma, Epithelioid- Leiomyosarcoma, Epithelioid
- Epithelioid Leiomyosarcoma
- Epithelioid Leiomyosarcomas
- Leiomyosarcomas, Epithelioid
Leiomyosarcoma, Myxoid- Leiomyosarcoma, Myxoid
- Leiomyosarcomas, Myxoid
- Myxoid Leiomyosarcoma
- Myxoid Leiomyosarcomas
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Below are MeSH descriptors whose meaning is more general than "Leiomyosarcoma".
Below are MeSH descriptors whose meaning is more specific than "Leiomyosarcoma".
This graph shows the total number of publications written about "Leiomyosarcoma" by people in this website by year, and whether "Leiomyosarcoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 3 | 1 | 4 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leiomyosarcoma" by people in Profiles.
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Wagner MJ, Zhang Y, Cranmer LD, Loggers ET, Black G, McDonnell S, Maxwell S, Johnson R, Moore R, Hermida de Viveiros P, Aicher L, Smythe KS, He Q, Jones RL, Pollack SM. A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma. Clin Cancer Res. 2022 06 01; 28(11):2306-2312.
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Smrke A, Benson C, Strauss DC, Hayes AJ, Thway K, Hallin M, Fisher C, Messiou C, Huang PH, Jones RL, Smith MJ. Gastrointestinal leiomyosarcoma demonstrate a predilection for distant recurrence and poor response to systemic treatments. Eur J Surg Oncol. 2021 10; 47(10):2595-2601.
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Gusho CA, Blank AT, Gitelis S. Comparison of clinicopathological features and outcomes in patients with primary leiomyosarcoma of bone and soft tissue. J Surg Oncol. 2021 Apr; 123(5):1274-1283.
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Ong CJ, Smith MJ, Snow HA, Benson C, Jones RL, Hayes AJ, Strauss DC. Primary iliocaval leiomyosarcomas: The path beyond surgery. Eur J Surg Oncol. 2020 05; 46(5):893-897.
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Jones RL, Maki RG, Patel SR, Wang G, McGowan TA, Shalaby WS, Knoblauch RE, von Mehren M, Demetri GD. Safety and efficacy of trabectedin when administered in the inpatient versus outpatient setting: Clinical considerations for outpatient administration of trabectedin. Cancer. 2019 Dec 15; 125(24):4435-4441.
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Jones RL, Le Cesne A, Ibrahim T, Garcia Del Muro X, Menge F. Preserving quality of life as a key treatment goal in advanced soft tissue sarcomas. Expert Rev Anticancer Ther. 2018 12; 18(12):1241-1248.
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Kolson Kokohaare E, Strauss DC, Jones RL, Thway K. Endometrial Stromal Sarcoma With Hyalinizing Giant Rosettes, Mimicking Low-Grade Fibromyxoid Sarcoma. Int J Surg Pathol. 2018 Sep; 26(6):525-527.
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Schneider N, Strauss DC, Smith MJ, Miah AB, Zaidi S, Benson C, van Houdt WJ, Jones RL, Hayes AJ, Fisher C, Thway K. The Adequacy of Core Biopsy in the Assessment of Smooth Muscle Neoplasms of Soft Tissues: Implications for Treatment and Prognosis. Am J Surg Pathol. 2017 Jul; 41(7):923-931.
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Setola E, Noujaim J, Benson C, Chawla S, Palmerini E, Jones RL. Eribulin in advanced liposarcoma and leiomyosarcoma. Expert Rev Anticancer Ther. 2017 08; 17(8):717-723.
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Hensley ML, Patel SR, von Mehren M, Ganjoo K, Jones RL, Staddon A, Rushing D, Milhem M, Monk B, Wang G, McCarthy S, Knoblauch RE, Parekh TV, Maki RG, Demetri GD. Efficacy and safety of trabectedin or dacarbazine in patients with advanced uterine leiomyosarcoma after failure of anthracycline-based chemotherapy: Subgroup analysis of a phase 3, randomized clinical trial. Gynecol Oncol. 2017 09; 146(3):531-537.
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