Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.

Descriptor ID	D000074261
MeSH Number(s)	D08.811.520.650.600.500.250 D12.776.543.750.700.250 D12.776.543.750.750.025
Concept/Terms	Receptors, Enterotoxin Receptors, Enterotoxin Enterotoxin-Guanylin Receptors Enterotoxin Guanylin Receptors Receptors, Enterotoxin-Guanylin Receptors, Guanyl Cyclase-C Receptors, Guanyl Cyclase C Guanyl Cyclase-C Receptors Cyclase-C Receptors, Guanyl Guanyl Cyclase C Receptors Guanylin-Uroguanylin Receptors Guanylin Uroguanylin Receptors Receptors, Guanylin-Uroguanylin Heat-Stable Enterotoxin Receptors Enterotoxin Receptors, Heat-Stable Heat Stable Enterotoxin Receptors Receptors, Heat-Stable Enterotoxin Enterotoxin Receptors GC-C Receptors GC C Receptors Receptors, GC-C Enterotoxin Receptor Enterotoxin Receptor Enterotoxin-Guanylin Receptor Enterotoxin Guanylin Receptor Receptor, Enterotoxin-Guanylin Guanyl Cyclase-C Receptor Guanyl Cyclase C Receptor Receptor, Guanyl Cyclase-C Receptor, Guanyl Cyclase C Guanylyl Cyclase C Cyclase C, Guanylyl Heat-Stable Enterotoxin Receptor Enterotoxin Receptor, Heat-Stable Heat Stable Enterotoxin Receptor Receptor, Heat-Stable Enterotoxin Receptor, Enterotoxin GC-C Receptor GC C Receptor Receptor, GC-C Guanylin-Uroguanylin Receptor Guanylin Uroguanylin Receptor Receptor, Guanylin-Uroguanylin

Below are MeSH descriptors whose meaning is more general than "Receptors, Enterotoxin".

Below are MeSH descriptors whose meaning is related to "Receptors, Enterotoxin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Enterotoxin".