Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

Descriptor ID	D007969
MeSH Number(s)	C10.228.140.300.700 C10.228.140.461.550 C14.907.253.612 C16.614.521.450
Concept/Terms	Leukomalacia, Periventricular Leukomalacia, Periventricular Periventricular Leukomalacia Leukomalacias, Periventricular Periventricular Leukomalacias Encephalomalacia, Periventricular Encephalomalacias, Periventricular Periventricular Encephalomalacia Periventricular Encephalomalacias Leucomalacia, Periventricular Leucomalacias, Periventricular Periventricular Leucomalacia Periventricular Leucomalacias Neonatal Cerebral Leukomalacia Neonatal Cerebral Leukomalacia Cerebral Leukomalacia, Neonatal Cerebral Leukomalacias, Neonatal Leukomalacia, Neonatal Cerebral Leukomalacias, Neonatal Cerebral Neonatal Cerebral Leukomalacias Cystic Periventricular Leukomalacia Cystic Periventricular Leukomalacia Cystic Periventricular Leukomalacias Leukomalacia, Cystic Periventricular Leukomalacias, Cystic Periventricular Periventricular Leukomalacia, Cystic Periventricular Leukomalacias, Cystic

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