Particle-induced osteolysis is not accompanied by systemic remodeling but is reflected by systemic bone biomarkers.
Ross RD, Virdi AS, Liu S, Sena K, Sumner DR. Particle-induced osteolysis is not accompanied by systemic remodeling but is reflected by systemic bone biomarkers. J Orthop Res. 2014 Jul; 32(7):967-73.