 Phenobarbital
"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
| Descriptor ID |
D010634
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| MeSH Number(s) |
D03.383.742.698.253.650
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| Concept/Terms |
Phenobarbital- Phenobarbital
- Phenobarbitone
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenylbarbital
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
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Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenobarbital" by people in Profiles.
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Bhalla D, Aziz H, Bergen D, Birbeck GL, Carpio A, Cavalheiro E, Chivorakoun P, Helen Cross J, Houinato D, Newton CR, Odermatt P, Ravat S, Schmutzhard E, Preux PM. Undue regulatory control on phenobarbital--an important yet overlooked reason for the epilepsy treatment gap. Epilepsia. 2015 Apr; 56(4):659-62.
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Bleck TP. Intensive care unit management of patients with status epilepticus. Epilepsia. 2007; 48 Suppl 8:59-60.
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Bleck TP. Management approaches to prolonged seizures and status epilepticus. Epilepsia. 1999; 40 Suppl 1:S59-63; discussion S64-6.
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McLeod R, Mack D, Foss R, Boyer K, Withers S, Levin S, Hubbell J. Levels of pyrimethamine in sera and cerebrospinal and ventricular fluids from infants treated for congenital toxoplasmosis. Toxoplasmosis Study Group. Antimicrob Agents Chemother. 1992 May; 36(5):1040-8.
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Bleck TP. Therapy for status epilepticus. Clin Neuropharmacol. 1983; 6(4):255-69.
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