"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
| Descriptor ID |
D016264
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| MeSH Number(s) |
D09.698.365.272.300
|
| Concept/Terms |
Dextran Sulfate Sodium- Dextran Sulfate Sodium
- Sulfate Sodium, Dextran
- Sodium Dextran Sulfate
- Dextran Sulfate, Sodium
- Sulfate, Sodium Dextran
|
Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".
Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".
This graph shows the total number of publications written about "Dextran Sulfate" by people in this website by year, and whether "Dextran Sulfate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.
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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis. Inflamm Bowel Dis. 2023 03 01; 29(3):444-457.
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Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. Acta Neuropathol Commun. 2021 08 19; 9(1):139.
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Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2):G220-7.
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Sleep deprivation worsens inflammation and delays recovery in a mouse model of colitis. Sleep Med. 2009 Jun; 10(6):597-603.
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Adverse effects of chronic circadian desynchronization in animals in a "challenging" environment. Am J Physiol Regul Integr Comp Physiol. 2008 Dec; 295(6):R2034-40.
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A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells. J Clin Invest. 1999 Dec; 104(11):1539-47.