 Nociceptors
"Nociceptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D009619
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| MeSH Number(s) |
A08.675.650.915.875 A08.800.950.875 A11.671.650.915.875
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| Concept/Terms |
Nociceptors- Nociceptors
- Nociceptor
- Pain Receptors
- Pain Receptor
- Receptors, Pain
- Nociceptive Neurons
- Neuron, Nociceptive
- Neurons, Nociceptive
- Nociceptive Neuron
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Below are MeSH descriptors whose meaning is more general than "Nociceptors".
Below are MeSH descriptors whose meaning is more specific than "Nociceptors".
This graph shows the total number of publications written about "Nociceptors" by people in this website by year, and whether "Nociceptors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2015 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2019 | 2 | 0 | 2 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nociceptors" by people in Profiles.
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Obeidat AM, Wood MJ, Adamczyk NS, Ishihara S, Li J, Wang L, Ren D, Bennett DA, Miller RJ, Malfait AM, Miller RE. Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis. Nat Commun. 2023 04 29; 14(1):2479.
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Miller RJ, Malfait AM, Miller RE. The innate immune response as a mediator of osteoarthritis pain. Osteoarthritis Cartilage. 2020 05; 28(5):562-571.
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Obeidat AM, Miller RE, Miller RJ, Malfait AM. The nociceptive innervation of the normal and osteoarthritic mouse knee. Osteoarthritis Cartilage. 2019 11; 27(11):1669-1679.
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Miller RE, Kim YS, Tran PB, Ishihara S, Dong X, Miller RJ, Malfait AM. Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging. Arthritis Rheumatol. 2018 01; 70(1):88-97.
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Miller RE, Belmadani A, Ishihara S, Tran PB, Ren D, Miller RJ, Malfait AM. Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis Rheumatol. 2015 Nov; 67(11):2933-43.
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Miller RE, Tran PB, Obeidat AM, Raghu P, Ishihara S, Miller RJ, Malfait AM. The Role of Peripheral Nociceptive Neurons in the Pathophysiology of Osteoarthritis Pain. Curr Osteoporos Rep. 2015 Oct; 13(5):318-26.
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Das V. An introduction to pain pathways and pain "targets". Prog Mol Biol Transl Sci. 2015; 131:1-30.
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Im HJ, Kim JS, Li X, Kotwal N, Sumner DR, van Wijnen AJ, Davis FJ, Yan D, Levine B, Henry JL, Desevr? J, Kroin JS. Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. Arthritis Rheum. 2010 Oct; 62(10):2995-3005.
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McCarthy RJ, Kroin JS, Lubenow TR, Penn RD, Ivankovich AD. Effect of intrathecal tizanidine on antinociception and blood pressure in the rat. Pain. 1990 Mar; 40(3):333-338.
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