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Igor J. Koralnik

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentNeurological Sciences
Address
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    Collapse Overview 
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    My Scopus ID is 7003930241.
    My NIH COMMONS name is IKORALNI.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Musukuma-Chifulo K, Ghebremichael M, Chilyabanyama ON, Bates M, Munsaka S, Simuyandi M, Chisenga C, Tembo J, Sinkala E, Koralnik IJ, Dang X, Chilengi R, Siddiqi OK. Characterizing Epstein-Barr virus infection of the central nervous system in Zambian adults living with HIV. J Neurovirol. 2023 Oct 30. PMID: 37902948.
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    2. Batra A, Nath A, Koralnik IJ. Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 10 17; 330(15):1491-1492. PMID: 37847279.
      View in: PubMed
    3. Frontera JA, Guekht A, Allegri RF, Ashraf M, Baykan B, Crivelli L, Easton A, Garcia-Azorin D, Helbok R, Joshi J, Koehn J, Koralnik I, Netravathi M, Michael B, Nilo A, ?zge A, Padda K, Pellitteri G, Prasad K, Romozzi M, Saylor D, Seed A, Thakur K, Uluduz D, Vogrig A, Welte TM, Westenberg E, Zhuravlev D, Zinchuk M, Winkler AS. Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition. J Neurol Sci. 2023 Oct 13; 454:120827. PMID: 37856998.
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    4. Hanson BA, Visvabharathy L, Orban ZS, Jimenez M, Batra A, Liotta EM, DeLisle RK, Klausner JD, Cohen P, Padhye AS, Tachas G, Koralnik IJ. Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection. Brain Behav Immun. 2023 Nov; 114:462-474. PMID: 37704012.
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    5. Visvabharathy L, Hanson BA, Orban ZS, Lim PH, Palacio NM, Jimenez M, Clark JR, Graham EL, Liotta EM, Tachas G, Penaloza-MacMaster P, Koralnik IJ. Corrigendum: Neuro-PASC is characterized by enhanced CD4+ and diminished CD8+ T cell responses to SARSCoV-2 Nucleocapsid protein. Front Immunol. 2023; 14:1275925. PMID: 37691950.
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    6. Orban ZS, Visvabharathy L, Perez Giraldo GS, Jimenez M, Koralnik IJ. SARS-CoV-2-Specific Immune Responses in Patients With Postviral Syndrome After Suspected COVID-19. Neurol Neuroimmunol Neuroinflamm. 2023 11; 10(6). PMID: 37612134.
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    7. Visvabharathy L, Hanson BA, Orban ZS, Lim PH, Palacio NM, Jimenez M, Clark JR, Graham EL, Liotta EM, Tachas G, Penaloza-MacMaster P, Koralnik IJ. Neuro-PASC is characterized by enhanced CD4+ and diminished CD8+ T cell responses to SARS-CoV-2 Nucleocapsid protein. Front Immunol. 2023; 14:1155770. PMID: 37313412.
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    8. Bailey J, Lavelle B, Miller J, Jimenez M, Lim PH, Orban ZS, Clark JR, Tomar R, Ludwig A, Ali ST, Lank GK, Zielinski A, Mylvaganam R, Kalhan R, El Muayed M, Mutharasan RK, Liotta EM, Sznajder JI, Davidson C, Koralnik IJ, Sala MA. Multidisciplinary Center Care for Long COVID Syndrome-A Retrospective Cohort Study. Am J Med. 2023 May 22. PMID: 37220832.
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    9. Perez Giraldo GS, Ali ST, Kang AK, Patel TR, Budhiraja S, Gaelen JI, Lank GK, Clark JR, Mukherjee S, Singer T, Venkatesh A, Orban ZS, Lim PH, Jimenez M, Miller J, Taylor C, Szymanski AL, Scarpelli J, Graham EL, Balabanov RD, Barcelo BE, Cahan JG, Ruckman K, Shepard AG, Slutzky MW, LaFaver K, Kumthekar PU, Shetty NK, Carroll KS, Ho SU, Lukas RV, Batra A, Liotta EM, Koralnik IJ. Neurologic Manifestations of Long COVID Differ Based on Acute COVID-19 Severity. Ann Neurol. 2023 07; 94(1):146-159. PMID: 36966460.
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    10. Visvabharathy L, Zhu C, Orban ZS, Yarnoff K, Palacio N, Jimenez M, Lim PH, Penaloza-MacMaster P, Koralnik IJ. Autoantibody production is enhanced after mild SARS-CoV-2 infection despite vaccination in individuals with and without long COVID. medRxiv. 2023 Apr 12. PMID: 37090595.
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    11. Dangi T, Sanchez S, Lew MH, Awakoaiye B, Visvabharathy L, Richner JM, Koralnik IJ, Penaloza-MacMaster P. Pre-existing immunity modulates responses to mRNA boosters. Cell Rep. 2023 03 28; 42(3):112167. PMID: 36857186.
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    12. Hatchwell E, Smith EB, Jalilzadeh S, Bruno CD, Taoufik Y, Hendel-Chavez H, Liblau R, Brassat D, Martin-Blondel G, Wiendl H, Schwab N, Cortese I, Monaco MC, Imberti L, Capra R, Oksenberg JR, Gasnault J, Stankoff B, Richmond TA, Rancour DM, Koralnik IJ, Hanson BA, Major EO, Chow CR, Eis PS. Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies. Front Neurol. 2022; 13:1016377. PMID: 36588876.
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    13. Dangi T, Sanchez S, Class J, Richner M, Visvabharathy L, Chung YR, Bentley K, Stanton RJ, Koralnik IJ, Richner JM, Penaloza-MacMaster P. Improved control of SARS-CoV-2 by treatment with a nucleocapsid-specific monoclonal antibody. J Clin Invest. 2022 12 01; 132(23). PMID: 36219482.
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    14. Adrissi J, Chomba M, Chishimba L, Zimba S, Koralnik IJ, Saylor D. The case of a 42-year-old man with progressive gait instability, dysarthria, and dysphagia. Ann Clin Transl Neurol. 2023 01; 10(1):144-145. PMID: 36350078.
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    15. Visvabharathy L, Hanson BA, Orban ZS, Lim PH, Palacio NM, Jimenez M, Clark JR, Graham EL, Liotta EM, Tachas G, Penaloza-MacMaster P, Koralnik IJ. T cell responses to SARS-CoV-2 in people with and without neurologic symptoms of long COVID. medRxiv. 2022 Oct 21. PMID: 34401886.
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    16. Visvabharathy L, Orban ZS, Koralnik IJ. Case report: Treatment of long COVID with a SARS-CoV-2 antiviral and IL-6 blockade in a patient with rheumatoid arthritis and SARS-CoV-2 antigen persistence. Front Med (Lausanne). 2022; 9:1003103. PMID: 36213654.
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    17. Musukuma-Chifulo K, Siddiqi OK, Chilyabanyama ON, Bates M, Chisenga CC, Simuyandi M, Sinkala E, Dang X, Koralnik IJ, Chilengi R, Munsaka S. Epstein-Barr Virus Detection in the Central Nervous System of HIV-Infected Patients. Pathogens. 2022 Sep 22; 11(10). PMID: 36297137.
      View in: PubMed
    18. Chomba M, Siddiqi OK, Fwoloshi S, Mubanga E, Koralnik IJ, Marra C, Saylor D. Clinical presentation and outcomes of syphilitic meningitis among hospitalized adults in lusaka, Zambia. Int J STD AIDS. 2022 10; 33(12):1038-1044. PMID: 36113438.
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    19. Graham EL, Koralnik IJ, Liotta EM. Therapeutic Approaches to the Neurologic Manifestations of COVID-19. Neurotherapeutics. 2022 09; 19(5):1435-1466. PMID: 35861926.
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    20. Dangi T, Sanchez S, Lew MH, Visvabharathy L, Richner J, Koralnik IJ, Penaloza-MacMaster P. Pre-existing immunity modulates responses to mRNA boosters. bioRxiv. 2022 Jun 28. PMID: 35794898.
      View in: PubMed
    21. Ali ST, Kang AK, Patel TR, Clark JR, Perez-Giraldo GS, Orban ZS, Lim PH, Jimenez M, Graham EL, Batra A, Liotta EM, Koralnik IJ. Evolution of neurologic symptoms in non-hospitalized COVID-19 "long haulers". Ann Clin Transl Neurol. 2022 07; 9(7):950-961. PMID: 35607826.
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    22. Batra A, Clark JR, Kang AK, Ali S, Patel TR, Shlobin NA, Hoffman SC, Lim PH, Orban ZS, Visvabharathy L, Graham EL, Sullivan DP, Muller WA, Chou SH, Ungv?ri Z, Koralnik IJ, Liotta EM. Persistent viral RNA shedding of SARS-CoV-2 is associated with delirium incidence and six-month mortality in hospitalized COVID-19 patients. Geroscience. 2022 06; 44(3):1241-1254. PMID: 35538386.
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    23. Ravishankar M, Dallah I, Mathews M, Bositis CM, Mwenechanya M, Kalungwana-Mambwe L, Bearden D, Navis A, Elafros MA, Gelbard H, Theodore WH, Koralnik IJ, Okulicz JF, Johnson BA, Belessiotis C, Ciccone O, Thornton N, Tsuboyama M, Siddiqi OK, Potchen MJ, Sikazwe I, Birbeck GL. Clinical characteristics and outcomes after new-onset seizure among Zambian children with HIV during the antiretroviral therapy era. Epilepsia Open. 2022 06; 7(2):315-324. PMID: 35305291.
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    24. Wechsler LR, Koralnik IJ. Global Teleneurology. Ann Neurol. 2022 04; 91(4):443-444. PMID: 35218048.
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    25. Hanson BA, Visvabharathy L, Ali ST, Kang AK, Patel TR, Clark JR, Lim PH, Orban ZS, Hwang SS, Mattoon D, Batra A, Liotta EM, Koralnik IJ. Plasma Biomarkers of Neuropathogenesis in Hospitalized Patients With COVID-19 and Those With Postacute Sequelae of SARS-CoV-2 Infection. Neurol Neuroimmunol Neuroinflamm. 2022 05; 9(3). PMID: 35256481.
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    26. Stamm B, Royan R, Clark JR, Hoffman SC, Shlobin NA, Orban ZS, Lim PH, Koralnik IJ, Liotta EM, Batra A. Patient Income Does Not Predict Disability or Mortality in Hospitalized COVID-19 Patients in a Large Health Care System in the Chicago Metropolitan Area. J Health Care Poor Underserved. 2022; 33(3):1215-1229. PMID: 36245159.
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    27. Dangi T, Palacio N, Sanchez S, Park M, Class J, Visvabharathy L, Ciucci T, Koralnik IJ, Richner JM, Penaloza-MacMaster P. Cross-protective immunity following coronavirus vaccination and coronavirus infection. J Clin Invest. 2021 12 15; 131(24). PMID: 34623973.
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    28. Siddiqi OK, Ghebremichael M, Musukuma K, Dang X, Mubanga E, Birbeck GL, Love S, Buback C, Kosloff B, Ayles H, Atadzhanov M, Koralnik IJ. LTA4H Prevalence and Mortality in Adult Zambians with Tuberculous Meningitis. Ann Neurol. 2021 12; 90(6):994-998. PMID: 34595756.
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    29. O'Hara BA, Gee GV, Haley SA, Morris-Love J, Nyblade C, Nieves C, Hanson BA, Dang X, Turner TJ, Chavin JM, Lublin A, Koralnik IJ, Atwood WJ. Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells. Int J Mol Sci. 2021 Sep 10; 22(18). PMID: 34575975.
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    30. Bernard-Valnet R, Koralnik IJ, Du Pasquier R. Advances in Treatment of Progressive Multifocal Leukoencephalopathy. Ann Neurol. 2021 12; 90(6):865-873. PMID: 34405435.
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    31. Patel A, Sul J, Gordon ML, Steinklein J, Sanguinetti S, Pramanik B, Purohit D, Haroutunian V, Williamson A, Koralnik I, Harel A. Progressive Multifocal Leukoencephalopathy in a Patient With Progressive Multiple Sclerosis Treated With Ocrelizumab Monotherapy. JAMA Neurol. 2021 06 01; 78(6):736-740. PMID: 33724354.
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    32. Clark JR, Batra A, Shlobin NA, Hoffman SC, Orban ZS, Koralnik IJ, Liotta EM. Acute-care hospital reencounters in COVID-19 patients. Geroscience. 2021 08; 43(4):2041-2053. PMID: 34019232.
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    33. Gonzalez H, Koralnik IJ, Huhn GD, Tantalo LC, Ritz EM, Orban Z, Marra CM. A Dual-Platform Point-of-Care Test for Neurosyphilis Diagnosis. Sex Transm Dis. 2021 05 01; 48(5):353-356. PMID: 33843803.
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    34. Graham EL, Clark JR, Orban ZS, Lim PH, Szymanski AL, Taylor C, DiBiase RM, Jia DT, Balabanov R, Ho SU, Batra A, Liotta EM, Koralnik IJ. Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 "long haulers". Ann Clin Transl Neurol. 2021 05; 8(5):1073-1085. PMID: 33755344.
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    35. Patel Z, Franz CK, Bharat A, Walter JM, Wolfe LF, Koralnik IJ, Deshmukh S. Diaphragm and Phrenic Nerve Ultrasound in COVID-19 Patients and Beyond: Imaging Technique, Findings, and Clinical Applications. J Ultrasound Med. 2022 Feb; 41(2):285-299. PMID: 33772850.
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    36. Liotta EM, Batra A, Koralnik IJ. Reader Response: A Prospective Study of Neurologic Disorders in Hospitalized Patients With COVID-19 in New York City. Neurology. 2021 03 16; 96(11):550. PMID: 33723026.
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    37. Clark JR, Liotta EM, Reish NJ, Shlobin NA, Hoffman SC, Orban ZS, Lim PH, Koralnik IJ, Batra A. Abnormal movements in hospitalized COVID-19 patients: A case series. J Neurol Sci. 2021 04 15; 423:117377. PMID: 33676146.
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    38. Liotta EM, Batra A, Koralnik IJ. Reply to COVID-19 encephalopathy, Bayes rule, and a plea for case-control studies. Ann Clin Transl Neurol. 2021 03; 8(3):726. PMID: 33512080.
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    39. Batra A, Clark JR, LaHaye K, Shlobin NA, Hoffman SC, Orban ZS, Colton K, Dematte JE, Sorond FA, Koralnik IJ, Liotta EM. Transcranial Doppler Ultrasound Evidence of Active Cerebral Embolization in COVID-19. J Stroke Cerebrovasc Dis. 2021 Mar; 30(3):105542. PMID: 33341023.
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    40. Fernandez CE, Franz CK, Ko JH, Walter JM, Koralnik IJ, Ahlawat S, Deshmukh S. Imaging Review of Peripheral Nerve Injuries in Patients with COVID-19. Radiology. 2021 03; 298(3):E117-E130. PMID: 33258748.
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    41. Breville G, Koralnik IJ, Lalive PH. Brainstem progressive multifocal leukoencephalopathy. Eur J Neurol. 2021 03; 28(3):1016-1021. PMID: 33128290.
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    42. Wijburg MT, Warnke C, McGuigan C, Koralnik IJ, Barkhof F, Killestein J, Wattjes MP. Pharmacovigilance during treatment of multiple sclerosis: early recognition of CNS complications. J Neurol Neurosurg Psychiatry. 2021 02; 92(2):177-188. PMID: 33229453.
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    43. Navis A, Dallah I, Mabeta C, Musukuma K, Siddiqi OK, Bositis CM, Koralnik IJ, Gelbard HA, Theodore WH, Okulicz JF, Johnson BA, Sikazwe I, Bearden DR, Birbeck GL. Evaluating the impact of antiretroviral and antiseizure medication interactions on treatment effectiveness among outpatient clinic attendees with HIV in Zambia. Epilepsia. 2020 12; 61(12):2705-2711. PMID: 33084053.
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    44. Liotta EM, Batra A, Clark JR, Shlobin NA, Hoffman SC, Orban ZS, Koralnik IJ. Frequent neurologic manifestations and encephalopathy-associated morbidity in Covid-19 patients. Ann Clin Transl Neurol. 2020 11; 7(11):2221-2230. PMID: 33016619.
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    45. Koralnik IJ, Tyler KL. COVID-19: A Global Threat to the Nervous System. Ann Neurol. 2020 07; 88(1):1-11. PMID: 32506549.
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    46. Eis PS, Bruno CD, Richmond TA, Koralnik IJ, Hanson BA, Major EO, Chow CR, Hendel-Chavez H, Stankoff B, Gasnault J, Taoufik Y, Hatchwell E. Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy. Front Neurol. 2020; 11:186. PMID: 32256442.
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    47. Sierra Morales F, Koralnik IJ, Gautam S, Samaan S, Sloane JA. Correction to: Risk factors for lymphopenia in patients with relapsing-remitting multiple sclerosis treated with dimethyl fumarate. J Neurol. 2020 01; 267(1):132. PMID: 31758256.
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    48. Cogswell AC, Maski K, Scammell TE, Tucker D, Orban ZS, Koralnik IJ. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019 12; 6(12):2566-2572. PMID: 31730293.
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    49. Waldrop G, Goetz TG, Siddiqi OK, Koralnik IJ, Shah H, Thakur KT. The World Health Organization's Essential Diagnostics List: Diagnostics for neurologic disorders. Neurology. 2019 10 08; 93(15):680-683. PMID: 31591174.
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    50. Morales FS, Koralnik IJ, Gautam S, Samaan S, Sloane JA. Risk factors for lymphopenia in patients with relapsing-remitting multiple sclerosis treated with dimethyl fumarate. J Neurol. 2020 01; 267(1):125-131. PMID: 31583427.
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    51. Tan CS, Ghofrani J, Geiger E, Koralnik IJ, Jost S. Brief Report: Decreased JC Virus-Specific Antibody-Dependent Cellular Cytotoxicity in HIV-Seropositive PML Survivors. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):220-224. PMID: 31513076.
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    52. Gonzalez H, Koralnik IJ, Marra CM. Neurosyphilis. Semin Neurol. 2019 08; 39(4):448-455. PMID: 31533185.
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    53. Warrior L, Weber KM, Daubert E, Morris MC, Agarwal P, Koralnik IJ, French AL. Olive Oil Intake Associated with Increased Attention Scores in Women Living with HIV: Findings from the Chicago Women's Interagency HIV Study. Nutrients. 2019 Jul 31; 11(8). PMID: 31370174.
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    54. Siddiqi OK, Birbeck GL, Ghebremichael M, Mubanga E, Love S, Buback C, Kosloff B, Ayles H, Atadzhanov M, Dheda K, Koralnik IJ. Prospective Cohort Study on Performance of Cerebrospinal Fluid (CSF) Xpert MTB/RIF, CSF Lipoarabinomannan (LAM) Lateral Flow Assay (LFA), and Urine LAM LFA for Diagnosis of Tuberculous Meningitis in Zambia. J Clin Microbiol. 2019 08; 57(8). PMID: 31189584.
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    55. Mubanga E, Patel A, Siddiqi OK, Hanson BA, Dang X, Lakhi S, Mulundu G, Bender N, Koralnik IJ. Progressive multifocal leukoencephalopathy in Zambia is caused by JC virus with prototype regulatory region. J Neurovirol. 2019 08; 25(4):475-479. PMID: 31028690.
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    56. Corbridge SM, Rice RC, Bean LA, W?thrich C, Dang X, Nicholson DA, Koralnik IJ. JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy. J Neurovirol. 2019 08; 25(4):520-524. PMID: 31025264.
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    57. Koralnik IJ. Can Immune Checkpoint Inhibitors Keep JC Virus in Check? N Engl J Med. 2019 04 25; 380(17):1667-1668. PMID: 30969502.
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    58. Stefoski D, Balabanov R, Waheed R, Ko M, Koralnik IJ, Sierra Morales F. Treatment of natalizumab-associated PML with filgrastim. Ann Clin Transl Neurol. 2019 May; 6(5):923-931. PMID: 31139690.
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    59. Mahoney CE, Cogswell A, Koralnik IJ, Scammell TE. The neurobiological basis of narcolepsy. Nat Rev Neurosci. 2019 02; 20(2):83-93. PMID: 30546103.
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    60. Elafros MA, Johnson BA, Siddiqi OK, Okulicz JF, Sikazwe I, Bositis CM, Potchen MJ, Koralnik IJ, Theodore WH, Kalungwana L, Birbeck GL. Mortality & recurrent seizure risk after new-onset seizure in HIV-positive Zambian adults. BMC Neurol. 2018 Dec 07; 18(1):201. PMID: 30522451.
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    61. Grandjean Lapierre S, Dang X, Gilbert D, Lauzier S, Koralnik IJ, LeBlanc L. JC Virus Granule Cell Neuronopathy as AIDS-Presenting Illness. Can J Neurol Sci. 2018 07; 45(4):466-469. PMID: 30056824.
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    62. Chalkias S, Gorham JM, Mazaika E, Parfenov M, Dang X, DePalma S, McKean D, Seidman CE, Seidman JG, Koralnik IJ. ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients. PLoS One. 2018; 13(1):e0186945. PMID: 29360822.
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    63. Brown MW, Foy KE, Chanda C, Mulundika J, Koralnik IJ, Siddiqi OK. Neurologic illness in Zambia: A neurointensivist's experience. J Neurol Sci. 2018 02 15; 385:140-143. PMID: 29406894.
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    64. Sierra Morales F, Illingworth C, Lin K, Rivera Agosto I, Powell C, Sloane JA, Koralnik IJ. PML-IRIS in an HIV-2-infected patient presenting as Bell's palsy. J Neurovirol. 2017 10; 23(5):789-792. PMID: 28831749.
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    65. Sierra Morales F, Wright RB, Novo JE, Arvanitis LD, Stefoski D, Koralnik IJ. Glioblastoma in natalizumab-treated multiple sclerosis patients. Ann Clin Transl Neurol. 2017 07; 4(7):512-516. PMID: 28695151.
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    66. Mukerji SS, Misra V, Lorenz D, Cervantes-Arslanian AM, Lyons J, Chalkias S, Wurcel A, Burke D, Venna N, Morgello S, Koralnik IJ, Gabuzda D. Temporal Patterns and Drug Resistance in CSF Viral Escape Among ART-Experienced HIV-1 Infected Adults. J Acquir Immune Defic Syndr. 2017 06 01; 75(2):246-255. PMID: 28328546.
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    67. Bialasiewicz S, Hart G, Oliver K, Agnihotri SP, Koralnik IJ, Viscidi R, Nissen MD, Sloots TP, Burke MT, Isbel NM, Burke J. A Difficult Decision: Atypical JC Polyomavirus Encephalopathy in a Kidney Transplant Recipient. Transplantation. 2017 06; 101(6):1461-1467. PMID: 27367472.
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    68. Siddiqi OK, Brown M, Cooper C, Atadzhanov M, Lakhi S, Koralnik IJ. Developing a successful global neurology program. Ann Neurol. 2017 02; 81(2):167-170. PMID: 28019673.
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    69. Siddiqi OK, Elafros MA, Bositis CM, Koralnik IJ, Theodore WH, Okulicz JF, Kalungwana L, Potchen MJ, Sikazwe I, Birbeck GL. New-onset seizure in HIV-infected adult Zambians: A search for causes and consequences. Neurology. 2017 01 31; 88(5):477-482. PMID: 28003499.
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    70. Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA, Anders RA, Sosman JA, Moslehi JJ. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. N Engl J Med. 2016 Nov 03; 375(18):1749-1755. PMID: 27806233.
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    71. Baharnoori M, Lyons J, Dastagir A, Koralnik I, Stankiewicz JM. Nonfatal PML in a patient with multiple sclerosis treated with dimethyl fumarate. Neurol Neuroimmunol Neuroinflamm. 2016 Oct; 3(5):e274. PMID: 27606353.
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    72. Soleimani-Meigooni DN, Schwetye KE, Angeles MR, Ryschkewitsch CF, Major EO, Dang X, Koralnik IJ, Schmidt RE, Clifford DB, Kuhlmann FM, Bucelli RC. JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7. J Neurovirol. 2017 02; 23(1):141-146. PMID: 27421731.
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    73. Miskin DP, Saadi A, Chikoya L, Sloane JA, Koralnik IJ, Siddiqi OK. Challenges in the diagnosis and treatment of CNS demyelinating disorders in Zambia. Mult Scler J Exp Transl Clin. 2016 Jan-Dec; 2:2055217316657117. PMID: 28607733.
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    74. W?thrich C, Batson S, Anderson MP, White LR, Koralnik IJ. JC Virus Infects Neurons and Glial Cells in the Hippocampus. J Neuropathol Exp Neurol. 2016 08; 75(8):712-717. PMID: 27297673.
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    75. Xue Y, Ratushny V, Koralnik IJ, Schlaug G, Wu PA. Allergic Dermatitis Caused by Endovascular Coiling of Brain Aneurysm. Dermatitis. 2016 May-Jun; 27(3):149-50. PMID: 27172313.
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    76. Miskin DP, Ngo LH, Koralnik IJ. Diagnostic delay in progressive multifocal leukoencephalopathy. Ann Clin Transl Neurol. 2016 May; 3(5):386-91. PMID: 27231708.
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    77. Miskin DP, Chalkias SG, Dang X, Bord E, Batson S, Koralnik IJ. Interleukin-7 treatment of PML in a patient with idiopathic lymphocytopenia. Neurol Neuroimmunol Neuroinflamm. 2016 Apr; 3(2):e213. PMID: 27144212.
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    78. Crossley KM, Agnihotri S, Chaganti J, Rodriguez ML, McNally LP, Venna N, Turbett SE, Gutman M, Morey A, Koralnik IJ, Brew BJ. Recurrence of progressive multifocal leukoencephalopathy despite immune recovery in two HIV seropositive individuals. J Neurovirol. 2016 08; 22(4):541-5. PMID: 26727910.
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    79. Miskin DP, Herman ST, Ngo LH, Koralnik IJ. Predictors and characteristics of seizures in survivors of progressive multifocal leukoencephalopathy. J Neurovirol. 2016 08; 22(4):464-71. PMID: 26676826.
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    80. Chalkias SG, Gheuens S, Bord E, Batson S, Koralnik IJ. Brief Report: Role of Thymic Reconstitution in the Outcome of AIDS-Related PML. J Acquir Immune Defic Syndr. 2015 Dec 01; 70(4):357-61. PMID: 26181821.
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    81. Kaliyaperumal S, W?thrich C, Westmoreland SV, Koralnik IJ. Simian Virus 40 Infection in the Spinal Cord of Simian Immunodeficiency Virus-Immunosuppressed Rhesus Macaques. J Neuropathol Exp Neurol. 2015 Nov; 74(11):1071-6. PMID: 26469249.
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    82. W?thrich C, Batson S, Koralnik IJ. Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hamper Detection of Neurons by T Lymphocytes in the Central Nervous System. J Neuropathol Exp Neurol. 2015 Aug; 74(8):791-803. PMID: 26115192.
      View in: PubMed
    83. Bartsch T, Rempe T, Wrede A, Leypoldt F, Br?ck W, Adams O, Rohr A, Jansen O, W?thrich C, Deuschl G, Koralnik IJ. Progressive neurologic dysfunction in a psoriasis patient treated with dimethyl fumarate. Ann Neurol. 2015 Oct; 78(4):501-14. PMID: 26150206.
      View in: PubMed
    84. Sikazwe I, Elafros MA, Bositis CM, Siddiqi OK, Koralnik IJ, Kalungwana L, Theodore WH, Okulicz JF, Potchen MJ, Birbeck GL. HIV and new onset seizures: slipping through the cracks in HIV care and treatment. HIV Med. 2016 Feb; 17(2):118-23. PMID: 26200721.
      View in: PubMed
    85. Dang X, Chalkias S, Koralnik IJ. JC virus-iLOV fluorescent strains enable the detection of early and late viral protein expression. J Virol Methods. 2015 Oct; 223:25-9. PMID: 26205551.
      View in: PubMed
    86. Miskin DP, Koralnik IJ. Novel syndromes associated with JC virus infection of neurons and meningeal cells: no longer a gray area. Curr Opin Neurol. 2015 Jun; 28(3):288-94. PMID: 25887767.
      View in: PubMed
    87. Agnihotri SP, Koralnik IJ. Training for a neurology career in a rare disease: The role of cyberconsults. Ann Neurol. 2015 May; 77(5):738-40. PMID: 25707384.
      View in: PubMed
    88. Siddiqi OK, Elafros MA, Sikazwe I, Birbeck GL, Kalungwana L, Potchen MJ, Bositis CM, Koralnik IJ, Theodore WH. Acute EEG findings in HIV-infected Zambian adults with new-onset seizure. Neurology. 2015 Mar 31; 84(13):1317-22. PMID: 25740861.
      View in: PubMed
    89. Satyanarayana G, Hammond SP, Broge TA, Mackenzie MR, Viscidi R, Politikos I, Koralnik IJ, Cutler CS, Ballen K, Boussiotis V, Marty FM, Tan CS. BK polyomavirus reactivation after reduced-intensity double umbilical cord blood cell transplantation. Transpl Immunol. 2015 Mar; 32(2):116-20. PMID: 25536223.
      View in: PubMed
    90. Koralnik IJ. Finger pointing to JC virus: a tale of two indexes. Ann Neurol. 2014 Dec; 76(6):789-91. PMID: 25380145.
      View in: PubMed
    91. Potchen MJ, Siddiqi OK, Elafros MA, Koralnik IJ, Theodore WH, Sikazwe I, Kalungwana L, Bositis CM, Birbeck GL. Neuroimaging abnormalities and seizure recurrence in a prospective cohort study of zambians with human immunodeficiency virus and first seizure. Neurol Int. 2014 Oct 23; 6(4):5547. PMID: 25568738.
      View in: PubMed
    92. Kalungwana L, Elafros MA, Siddiqi OK, Bositis CM, Sikazwe I, Koralnik IJ, Theodore WH, Birbeck GL. Cognitive impairment and psychiatric morbidity in HIV+ Zambians with new-onset seizure. Am J Trop Med Hyg. 2014 Dec; 91(6):1254-8. PMID: 25311691.
      View in: PubMed
    93. Ellis LC, Koralnik IJ. JC virus nucleotides 376-396 are critical for VP1 capsid protein expression. J Neurovirol. 2015 Dec; 21(6):671-8. PMID: 25142442.
      View in: PubMed
    94. Agnihotri SP, Dang X, Carter JL, Fife TD, Bord E, Batson S, Koralnik IJ. JCV GCN in a natalizumab-treated MS patient is associated with mutations of the VP1 capsid gene. Neurology. 2014 Aug 19; 83(8):727-32. PMID: 25037207.
      View in: PubMed
    95. Agnihotri SP, Wuthrich C, Dang X, Nauen D, Karimi R, Viscidi R, Bord E, Batson S, Troncoso J, Koralnik IJ. A fatal case of JC virus meningitis presenting with hydrocephalus in a human immunodeficiency virus-seronegative patient. Ann Neurol. 2014 Jul; 76(1):140-7. PMID: 24895208.
      View in: PubMed
    96. Chalkias S, Dang X, Bord E, Stein MC, Kinkel RP, Sloane JA, Donnelly M, Ionete C, Houtchens MK, Buckle GJ, Batson S, Koralnik IJ. JC virus reactivation during prolonged natalizumab monotherapy for multiple sclerosis. Ann Neurol. 2014 Jun; 75(6):925-34. PMID: 24687904.
      View in: PubMed
    97. Khoury MN, Alsop DC, Agnihotri SP, Pfannl R, Wuthrich C, Ho ML, Hackney D, Ngo L, Anderson MP, Koralnik IJ. Hyperintense cortical signal on magnetic resonance imaging reflects focal leukocortical encephalitis and seizure risk in progressive multifocal leukoencephalopathy. Ann Neurol. 2014 May; 75(5):659-69. PMID: 24752885.
      View in: PubMed
    98. Dang L, Dang X, Koralnik IJ, Todd PK. JC polyomavirus granule cell neuronopathy in a patient treated with rituximab. JAMA Neurol. 2014 Apr; 71(4):487-9. PMID: 24515530.
      View in: PubMed
    99. Schwenk H, Ramirez-Avila L, Sheu SH, Wuthrich C, Waugh J, Was A, Degirolami U, Burchett S, Koralnik IJ, Ahmed A. Progressive multifocal leukoencephalopathy in pediatric patients: case report and literature review. Pediatr Infect Dis J. 2014 Apr; 33(4):e99-105. PMID: 24632669.
      View in: PubMed
    100. Tan CS, Broge TA, Ngo L, Gheuens S, Viscidi R, Bord E, Rosenblatt J, Wong M, Avigan D, Koralnik IJ. Immune reconstitution after allogeneic hematopoietic stem cell transplantation is associated with selective control of JC virus reactivation. Biol Blood Marrow Transplant. 2014 Jul; 20(7):992-9. PMID: 24680976.
      View in: PubMed
    101. Siddiqi OK, Ghebremichael M, Dang X, Atadzhanov M, Kaonga P, Khoury MN, Koralnik IJ. Molecular diagnosis of central nervous system opportunistic infections in HIV-infected Zambian adults. Clin Infect Dis. 2014 Jun; 58(12):1771-7. PMID: 24668125.
      View in: PubMed
    102. Ellis LC, Norton E, Dang X, Koralnik IJ. Agnogene deletion in a novel pathogenic JC virus isolate impairs VP1 expression and virion production. PLoS One. 2013; 8(11):e80840. PMID: 24265839.
      View in: PubMed
    103. W?thrich C, Popescu BF, Gheuens S, Marvi M, Ziman R, Denq SP, Tham M, Norton E, Parisi JE, Dang X, Lucchinetti CF, Koralnik IJ. Natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis: a postmortem study. J Neuropathol Exp Neurol. 2013 Nov; 72(11):1043-51. PMID: 24128680.
      View in: PubMed
    104. Dang X, Koralnik IJ. Gone over to the dark side: Natalizumab-associated JC virus infection of neurons in cerebellar gray matter. Ann Neurol. 2013 Oct; 74(4):503-5. PMID: 23913509.
      View in: PubMed
    105. Kaliyaperumal S, Dang X, Wuethrich C, Knight HL, Pearson C, MacKey J, Mansfield KG, Koralnik IJ, Westmoreland SV. Frequent infection of neurons by SV40 virus in SIV-infected macaque monkeys with progressive multifocal leukoencephalopathy and meningoencephalitis. Am J Pathol. 2013 Dec; 183(6):1910-1917. PMID: 24095925.
      View in: PubMed
    106. Khoury MN, Mittleman MA, Koralnik IJ. ABO blood groups and risk for progressive multifocal leukoencephalopathy. JAMA Neurol. 2013 Oct; 70(10):1331-2. PMID: 24126810.
      View in: PubMed
    107. Khoury MN, Gheuens S, Ngo L, Wang X, Alsop DC, Koralnik IJ. Hyperperfusion in progressive multifocal leukoencephalopathy is associated with disease progression and absence of immune reconstitution inflammatory syndrome. Brain. 2013 Nov; 136(Pt 11):3441-50. PMID: 24088807.
      View in: PubMed
    108. Khoury MN, Tan CS, Peaslee M, Koralnik IJ. CSF viral escape in a patient with HIV-associated neurocognitive disorder. J Neurovirol. 2013 Aug; 19(4):402-5. PMID: 23737348.
      View in: PubMed
    109. Lach B, Connolly B, W?thrich C, Koralnik IJ. Inflammatory infratentorial progressive multifocal leukoencephalopathy in a patient with rheumatoid arthritis. Neuropathology. 2014 Feb; 34(1):39-44. PMID: 23683127.
      View in: PubMed
    110. Tan CS, Broge TA, Seung E, Vrbanac V, Viscidi R, Gordon J, Tager AM, Koralnik IJ. Detection of JC virus-specific immune responses in a novel humanized mouse model. PLoS One. 2013; 8(5):e64313. PMID: 23700470.
      View in: PubMed
    111. Berger JR, Aksamit AJ, Clifford DB, Davis L, Koralnik IJ, Sejvar JJ, Bartt R, Major EO, Nath A. PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology. 2013 Apr 09; 80(15):1430-8. PMID: 23568998.
      View in: PubMed
    112. Gheuens S, Buggy BP, Tlomak W, W?thrich C, Koralnik IJ. A game of viral hide and seek: miliary PML masquerading as EBV encephalitis in an HIV+ patient. Clin Neurol Neurosurg. 2013 Sep; 115(9):1861-3. PMID: 23535451.
      View in: PubMed
    113. Siddiqi OK, Koralnik IJ, Atadzhanov M, Birbeck GL. Emerging subspecialties in neurology: global health. Neurology. 2013 Feb 19; 80(8):e78-80. PMID: 23420898.
      View in: PubMed
    114. Koralnik IJ, Clifford DB. Comment: avoiding detrimental effects of corticosteroids on JC virus T-cell responses--primum non nocere. Neurology. 2012 Dec 04; 79(23):2263. PMID: 23175725.
      View in: PubMed
    115. Marousi S, Travasarou M, Karageorgiou CE, Gheuens S, Koralnik IJ. Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS. Neurology. 2012 Nov 20; 79(21):2160; author reply 2160. PMID: 23170016.
      View in: PubMed
    116. Gheuens S, W?thrich C, Koralnik IJ. Progressive multifocal leukoencephalopathy: why gray and white matter. Annu Rev Pathol. 2013 Jan 24; 8:189-215. PMID: 23092189.
      View in: PubMed
    117. Gheuens S, Ngo L, Wang X, Alsop DC, Lenkinski RE, Koralnik IJ. Metabolic profile of PML lesions in patients with and without IRIS: an observational study. Neurology. 2012 Sep 04; 79(10):1041-8. PMID: 22914832.
      View in: PubMed
    118. Tan CS, Bord E, Broge TA, Glotzbecker B, Mills H, Gheuens S, Rosenblatt J, Avigan D, Koralnik IJ. Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):244-8. PMID: 22549384.
      View in: PubMed
    119. Dang X, W?thrich C, Gordon J, Sawa H, Koralnik IJ. JC virus encephalopathy is associated with a novel agnoprotein-deletion JCV variant. PLoS One. 2012; 7(4):e35793. PMID: 22536439.
      View in: PubMed
    120. Gheuens S, Smith DR, Wang X, Alsop DC, Lenkinski RE, Koralnik IJ. Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS. Neurology. 2012 May 01; 78(18):1390-3. PMID: 22517104.
      View in: PubMed
    121. Sethi NK, Torgovnick J, McArthur JC, Tan IL, Koralnik IJ. Progressive multifocal leukoencephalopathy in a patient without immunodeficiency. Neurology. 2012 Jan 03; 78(1):73; author response 73-4. PMID: 22201115.
      View in: PubMed
    122. W?thrich C, Koralnik IJ. Frequent infection of cortical neurons by JC virus in patients with progressive multifocal leukoencephalopathy. J Neuropathol Exp Neurol. 2012 Jan; 71(1):54-65. PMID: 22157619.
      View in: PubMed
    123. Dang X, Vidal JE, Penalva de Oliveira AC, Simpson DM, Morgello S, Hecht JH, Ngo LH, Koralnik IJ. JC virus granule cell neuronopathy is associated with VP1 C terminus mutants. J Gen Virol. 2012 Jan; 93(Pt 1):175-183. PMID: 21940415.
      View in: PubMed
    124. Gheuens S, Cheeseman SH, Koralnik IJ. Hidden in plain view: emergence of progressive multifocal leukoencephalopathy after treatment of CNS toxoplasmosis. Acta Neurol Belg. 2011 Sep; 111(3):217-9. PMID: 22141286.
      View in: PubMed
    125. Viscidi RP, Khanna N, Tan CS, Li X, Jacobson L, Clifford DB, Nath A, Margolick JB, Shah KV, Hirsch HH, Koralnik IJ. JC virus antibody and viremia as predictors of progressive multifocal leukoencephalopathy in human immunodeficiency virus-1-infected individuals. Clin Infect Dis. 2011 Oct; 53(7):711-5. PMID: 21852452.
      View in: PubMed
    126. McGuire JL, Fridman V, W?thrich C, Koralnik IJ, Jacobs D. Progressive multifocal leukoencephalopathy associated with isolated CD8+ T-lymphocyte deficiency mimicking tumefactive MS. J Neurovirol. 2011 Oct; 17(5):500-3. PMID: 21786075.
      View in: PubMed
    127. Aquino K, Koralnik IJ, Silvers D. Clinical Reasoning: An 83-year-old woman with progressive hemiataxia, tremor, and infratentorial lesions. Neurology. 2011 Jul 12; 77(2):e7-10. PMID: 21747070.
      View in: PubMed
    128. Tan IL, Koralnik IJ, Rumbaugh JA, Burger PC, King-Rennie A, McArthur JC. Progressive multifocal leukoencephalopathy in a patient without immunodeficiency. Neurology. 2011 Jul 19; 77(3):297-9. PMID: 21734181.
      View in: PubMed
    129. Gheuens S, Bord E, Kesari S, Simpson DM, Gandhi RT, Clifford DB, Berger JR, Ngo L, Koralnik IJ. Role of CD4+ and CD8+ T-cell responses against JC virus in the outcome of patients with progressive multifocal leukoencephalopathy (PML) and PML with immune reconstitution inflammatory syndrome. J Virol. 2011 Jul; 85(14):7256-63. PMID: 21543472.
      View in: PubMed
    130. Dang X, Bialasiewicz S, Nissen MD, Sloots TP, Koralnik IJ, Tan CS. Infrequent detection of KI, WU and MC polyomaviruses in immunosuppressed individuals with or without progressive multifocal leukoencephalopathy. PLoS One. 2011 Mar 16; 6(3):e16736. PMID: 21436884.
      View in: PubMed
    131. Lima MA, Bernal-Cano F, Clifford DB, Gandhi RT, Koralnik IJ. Clinical outcome of long-term survivors of progressive multifocal leukoencephalopathy. J Neurol Neurosurg Psychiatry. 2010 Nov; 81(11):1288-91. PMID: 20710013.
      View in: PubMed
    132. Tan CS, Ellis LC, W?thrich C, Ngo L, Broge TA, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol. 2010 Sep; 84(18):9200-9. PMID: 20610709.
      View in: PubMed
    133. Tan CS, Chen Y, Viscidi RP, Kinkel RP, Stein MC, Koralnik IJ. Discrepant findings in immune responses to JC virus in patients receiving natalizumab. Lancet Neurol. 2010 Jun; 9(6):565-6; author reply 566-7. PMID: 20494320.
      View in: PubMed
    134. Tan CS, Koralnik IJ. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol. 2010 Apr; 9(4):425-37. PMID: 20298966.
      View in: PubMed
    135. Gheuens S, Fellay J, Goldstein DB, Koralnik IJ. Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy. J Neurovirol. 2010 Feb; 16(1):41-7. PMID: 20105104.
      View in: PubMed
    136. Siddiqi OK, Atadzhanov M, Birbeck GL, Koralnik IJ. The spectrum of neurological disorders in a Zambian tertiary care hospital. J Neurol Sci. 2010 Mar 15; 290(1-2):1-5. PMID: 20070986.
      View in: PubMed
    137. Marzocchetti A, Tompkins T, Clifford DB, Gandhi RT, Kesari S, Berger JR, Simpson DM, Prosperi M, De Luca A, Koralnik IJ. Determinants of survival in progressive multifocal leukoencephalopathy. Neurology. 2009 Nov 10; 73(19):1551-8. PMID: 19901246.
      View in: PubMed
    138. Gheuens S, Pierone G, Peeters P, Koralnik IJ. Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression. J Neurol Neurosurg Psychiatry. 2010 Mar; 81(3):247-54. PMID: 19828476.
      View in: PubMed
    139. Cinque P, Koralnik IJ, Gerevini S, Miro JM, Price RW. Progressive multifocal leukoencephalopathy in HIV-1 infection. Lancet Infect Dis. 2009 Oct; 9(10):625-36. PMID: 19778765.
      View in: PubMed
    140. Chen Y, Bord E, Tompkins T, Miller J, Tan CS, Kinkel RP, Stein MC, Viscidi RP, Ngo LH, Koralnik IJ. Asymptomatic reactivation of JC virus in patients treated with natalizumab. N Engl J Med. 2009 Sep 10; 361(11):1067-74. PMID: 19741227.
      View in: PubMed
    141. W?thrich C, Dang X, Westmoreland S, McKay J, Maheshwari A, Anderson MP, Ropper AH, Viscidi RP, Koralnik IJ. Fulminant JC virus encephalopathy with productive infection of cortical pyramidal neurons. Ann Neurol. 2009 Jun; 65(6):742-8. PMID: 19557867.
      View in: PubMed
    142. Tan CS, Dezube BJ, Bhargava P, Autissier P, W?thrich C, Miller J, Koralnik IJ. Detection of JC virus DNA and proteins in the bone marrow of HIV-positive and HIV-negative patients: implications for viral latency and neurotropic transformation. J Infect Dis. 2009 Mar 15; 199(6):881-8. PMID: 19434914.
      View in: PubMed
    143. W?thrich C, Cheng YM, Joseph JT, Kesari S, Beckwith C, Stopa E, Bell JE, Koralnik IJ. Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy. J Neuropathol Exp Neurol. 2009 Jan; 68(1):15-25. PMID: 19104450.
      View in: PubMed
    144. Marzocchetti A, Lima M, Tompkins T, Kavanagh DG, Gandhi RT, O'Neill DW, Bhardwaj N, Koralnik IJ. Efficient in vitro expansion of JC virus-specific CD8(+) T-cell responses by JCV peptide-stimulated dendritic cells from patients with progressive multifocal leukoencephalopathy. Virology. 2009 Jan 20; 383(2):173-7. PMID: 19062062.
      View in: PubMed
    145. Marzocchetti A, Wuthrich C, Tan CS, Tompkins T, Bernal-Cano F, Bhargava P, Ropper AH, Koralnik IJ. Rearrangement of the JC virus regulatory region sequence in the bone marrow of a patient with rheumatoid arthritis and progressive multifocal leukoencephalopathy. J Neurovirol. 2008 Oct; 14(5):455-8. PMID: 18989816.
      View in: PubMed
    146. Dang X, W?thrich C, Axthelm MK, Koralnik IJ. Productive simian virus 40 infection of neurons in immunosuppressed Rhesus monkeys. J Neuropathol Exp Neurol. 2008 Aug; 67(8):784-92. PMID: 18648324.
      View in: PubMed
    147. Kesari S, Akar S, Saad A, Drappatz J, Koralnik IJ, DeAngelo DJ. Progressive multifocal leukoencephalopathy in a patient with relapsed acute myelogenous leukemia. J Clin Oncol. 2008 Aug 01; 26(22):3804-7. PMID: 18669471.
      View in: PubMed
    148. Chen Y, Trofe J, Gordon J, Autissier P, Woodle ES, Koralnik IJ. BKV and JCV large T antigen-specific CD8+ T cell response in HLA A*0201+ kidney transplant recipients with polyomavirus nephropathy and patients with progressive multifocal leukoencephalopathy. J Clin Virol. 2008 Jun; 42(2):198-202. PMID: 18295538.
      View in: PubMed
    149. Bernal-Cano F, Joseph JT, Koralnik IJ. Spinal cord lesions of progressive multifocal leukoencephalopathy in an acquired immunodeficiency syndrome patient. J Neurovirol. 2007 Oct; 13(5):474-6. PMID: 17994433.
      View in: PubMed
    150. Yang W, Beaudoin EL, Lu L, Du Pasquier RA, Kuroda MJ, Willemsen RA, Koralnik IJ, Junghans RP. Chimeric immune receptors (CIRs) specific to JC virus for immunotherapy in progressive multifocal leukoencephalopathy (PML). Int Immunol. 2007 Sep; 19(9):1083-93. PMID: 17660502.
      View in: PubMed
    151. Verma S, Cikurel K, Koralnik IJ, Morgello S, Cunningham-Rundles C, Weinstein ZR, Bergmann C, Simpson DM. Mirtazapine in progressive multifocal leukoencephalopathy associated with polycythemia vera. J Infect Dis. 2007 Sep 01; 196(5):709-11. PMID: 17674313.
      View in: PubMed
    152. Lima MA, Katz-Brull R, Lenkinski RE, Nunez R, Feinrider D, Koralnik IJ. Remission of progressive multifocal leukoencephalopathy and primary central nervous system lymphoma in an HIV-infected patient. Eur J Neurol. 2007 Jun; 14(6):598-602. PMID: 17539934.
      View in: PubMed
    153. Lima MA, Marzocchetti A, Autissier P, Tompkins T, Chen Y, Gordon J, Clifford DB, Gandhi RT, Venna N, Berger JR, Koralnik IJ. Frequency and phenotype of JC virus-specific CD8+ T lymphocytes in the peripheral blood of patients with progressive multifocal leukoencephalopathy. J Virol. 2007 Apr; 81(7):3361-8. PMID: 17229701.
      View in: PubMed
    154. Dang X, Koralnik IJ. A granule cell neuron-associated JC virus variant has a unique deletion in the VP1 gene. J Gen Virol. 2006 Sep; 87(Pt 9):2533-2537. PMID: 16894191.
      View in: PubMed
    155. Vulliemoz S, Lurati-Ruiz F, Borruat FX, Delavelle J, Koralnik IJ, Kuntzer T, Bogousslavsky J, Picard F, Landis T, Du Pasquier RA. Favourable outcome of progressive multifocal leucoencephalopathy in two patients with dermatomyositis. J Neurol Neurosurg Psychiatry. 2006 Sep; 77(9):1079-82. PMID: 16914758.
      View in: PubMed
    156. Koralnik IJ. Progressive multifocal leukoencephalopathy revisited: Has the disease outgrown its name? Ann Neurol. 2006 Aug; 60(2):162-73. PMID: 16862584.
      View in: PubMed
    157. Du Pasquier RA, Stein MC, Lima MA, Dang X, Jean-Jacques J, Zheng Y, Letvin NL, Koralnik IJ. JC virus induces a vigorous CD8+ cytotoxic T cell response in multiple sclerosis patients. J Neuroimmunol. 2006 Jul; 176(1-2):181-6. PMID: 16750575.
      View in: PubMed
    158. Chen Y, Trofe J, Gordon J, Du Pasquier RA, Roy-Chaudhury P, Kuroda MJ, Woodle ES, Khalili K, Koralnik IJ. Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy. J Virol. 2006 Apr; 80(7):3495-505. PMID: 16537617.
      View in: PubMed
    159. W?thrich C, Kesari S, Kim WK, Williams K, Gelman R, Elmeric D, De Girolami U, Joseph JT, Hedley-Whyte T, Koralnik IJ. Characterization of lymphocytic infiltrates in progressive multifocal leukoencephalopathy: co-localization of CD8(+) T cells with JCV-infected glial cells. J Neurovirol. 2006 Apr; 12(2):116-28. PMID: 16798673.
      View in: PubMed
    160. Lima MA, Drislane FW, Koralnik IJ. Seizures and their outcome in progressive multifocal leukoencephalopathy. Neurology. 2006 Jan 24; 66(2):262-4. PMID: 16434670.
      View in: PubMed
    161. Du Pasquier RA, Autissier P, Zheng Y, Jean-Jacques J, Koralnik IJ. Presence of JC virus-specific CTL in the cerebrospinal fluid of PML patients: rationale for immune-based therapeutic strategies. AIDS. 2005 Dec 02; 19(18):2069-76. PMID: 16284455.
      View in: PubMed
    162. Lima MA, Auriel E, W?thrich C, Borenstein NM, Koralnik IJ. Progressive multifocal leukoencephalopathy as a complication of hepatitis C virus treatment in an HIV-negative patient. Clin Infect Dis. 2005 Aug 01; 41(3):417-9. PMID: 16007550.
      View in: PubMed
    163. Berger JR, Koralnik IJ. Progressive multifocal leukoencephalopathy and natalizumab--unforeseen consequences. N Engl J Med. 2005 Jul 28; 353(4):414-6. PMID: 15947082.
      View in: PubMed
    164. Koralnik IJ, W?thrich C, Dang X, Rottnek M, Gurtman A, Simpson D, Morgello S. JC virus granule cell neuronopathy: A novel clinical syndrome distinct from progressive multifocal leukoencephalopathy. Ann Neurol. 2005 Apr; 57(4):576-80. PMID: 15786466.
      View in: PubMed
    165. Dang X, Axthelm MK, Letvin NL, Koralnik IJ. Rearrangement of simian virus 40 regulatory region is not required for induction of progressive multifocal leukoencephalopathy in immunosuppressed rhesus monkeys. J Virol. 2005 Feb; 79(3):1361-6. PMID: 15650162.
      View in: PubMed
    166. Lima MA, Hanto DW, Curry MP, Wong MT, Dang X, Koralnik IJ. Atypical radiological presentation of progressive multifocal leukoencephalopathy following liver transplantation. J Neurovirol. 2005 Feb; 11(1):46-50. PMID: 15804958.
      View in: PubMed
    167. Lima MA, Koralnik IJ. New features of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy and natalizumab. J Neurovirol. 2005; 11 Suppl 3:52-7. PMID: 16540456.
      View in: PubMed
    168. Kim WK, Corey S, Chesney G, Knight H, Klumpp S, W?thrich C, Letvin N, Koralnik I, Lackner A, Veasey R, Williams K. Identification of T lymphocytes in simian immunodeficiency virus encephalitis: distribution of CD8+ T cells in association with central nervous system vessels and virus. J Neurovirol. 2004 Oct; 10(5):315-25. PMID: 15385254.
      View in: PubMed
    169. Katz-Brull R, Lenkinski RE, Du Pasquier RA, Koralnik IJ. Elevation of myoinositol is associated with disease containment in progressive multifocal leukoencephalopathy. Neurology. 2004 Sep 14; 63(5):897-900. PMID: 15365144.
      View in: PubMed
    170. Du Pasquier RA, Schmitz JE, Jean-Jacques J, Zheng Y, Gordon J, Khalili K, Letvin NL, Koralnik IJ. Detection of JC virus-specific cytotoxic T lymphocytes in healthy individuals. J Virol. 2004 Sep; 78(18):10206-10. PMID: 15331755.
      View in: PubMed
    171. Chen Y, Sharp PM, Fowkes M, Kocher O, Joseph JT, Koralnik IJ. Analysis of 15 novel full-length BK virus sequences from three individuals: evidence of a high intra-strain genetic diversity. J Gen Virol. 2004 Sep; 85(Pt 9):2651-2663. PMID: 15302959.
      View in: PubMed
    172. Axthelm MK, Koralnik IJ, Dang X, W?thrich C, Rohne D, Stillman IE, Letvin NL. Meningoencephalitis and demyelination are pathologic manifestations of primary polyomavirus infection in immunosuppressed rhesus monkeys. J Neuropathol Exp Neurol. 2004 Jul; 63(7):750-8. PMID: 15290900.
      View in: PubMed
    173. Du Pasquier RA, Kuroda MJ, Zheng Y, Jean-Jacques J, Letvin NL, Koralnik IJ. A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy. Brain. 2004 Sep; 127(Pt 9):1970-8. PMID: 15215217.
      View in: PubMed
    174. Trofe J, Gordon J, Roy-Chaudhury P, Koralnik IJ, Atwood WJ, Alloway RR, Khalili K, Woodle ES. Polyomavirus nephropathy in kidney transplantation. Prog Transplant. 2004 Jun; 14(2):130-40; quiz 141-2. PMID: 15264457.
      View in: PubMed
    175. Koralnik IJ. New insights into progressive multifocal leukoencephalopathy. Curr Opin Neurol. 2004 Jun; 17(3):365-70. PMID: 15167073.
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    176. Trofe J, Gordon J, Roy-Chaudhury P, Koralnik I, Atwood W, Eash S, Alloway RR, Khalili K, Alexander JW, Woodle ES. Basic and clinical research in polyomavirus nephropathy. Exp Clin Transplant. 2004 Jun; 2(1):162-73. PMID: 15859923.
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    177. Koralnik IJ, Schellingerhout D, Frosch MP. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2004. A 66-year-old man with progressive neurologic deficits. N Engl J Med. 2004 Apr 29; 350(18):1882-93. PMID: 15115835.
      View in: PubMed
    178. Du Pasquier RA, Kuroda MJ, Schmitz JE, Zheng Y, Martin K, Peyerl FW, Lifton M, Gorgone D, Autissier P, Letvin NL, Koralnik IJ. Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1(p36) in patients with proven or possible progressive multifocal leukoencephalopathy. J Virol. 2003 Nov; 77(22):11918-26. PMID: 14581528.
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    179. Du Pasquier RA, Corey S, Margolin DH, Williams K, Pfister LA, De Girolami U, Mac Key JJ, W?thrich C, Joseph JT, Koralnik IJ. Productive infection of cerebellar granule cell neurons by JC virus in an HIV+ individual. Neurology. 2003 Sep 23; 61(6):775-82. PMID: 14504320.
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    180. Kempf W, Kadin ME, Dvorak AM, Lord CC, Burg G, Letvin NL, Koralnik IJ. Endogenous retroviral elements, but not exogenous retroviruses, are detected in CD30-positive lymphoproliferative disorders of the skin. Carcinogenesis. 2003 Feb; 24(2):301-6. PMID: 12584181.
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    181. Du Pasquier RA, Koralnik IJ. Inflammatory reaction in progressive multifocal leukoencephalopathy: harmful or beneficial? J Neurovirol. 2003; 9 Suppl 1:25-31. PMID: 12709868.
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    182. Cinque P, Koralnik IJ, Clifford DB. The evolving face of human immunodeficiency virus-related progressive multifocal leukoencephalopathy: defining a consensus terminology. J Neurovirol. 2003; 9 Suppl 1:88-92. PMID: 12709878.
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    183. Koralnik IJ. Overview of the cellular immunity against JC virus in progressive multifocal leukoencephalopathy. J Neurovirol. 2002 Dec; 8 Suppl 2:59-65. PMID: 12491153.
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    184. Barouch DH, Faquin WC, Chen Y, Koralnik IJ, Robbins GK, Davis BT. BK virus-associated hemorrhagic cystitis in a Human Immunodeficiency Virus-infected patient. Clin Infect Dis. 2002 Aug 01; 35(3):326-9. PMID: 12115100.
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    185. Kim JY, Koralnik IJ, LeFave M, Segal RA, Pfister LA, Pomeroy SL. Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences. Neuro Oncol. 2002 07; 4(3):165-70. PMID: 12084346.
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    186. Koralnik IJ, Du Pasquier RA, Kuroda MJ, Schmitz JE, Dang X, Zheng Y, Lifton M, Letvin NL. Association of prolonged survival in HLA-A2+ progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. J Immunol. 2002 Jan 01; 168(1):499-504. PMID: 11751998.
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    187. Du Pasquier RA, Clark KW, Smith PS, Joseph JT, Mazullo JM, De Girolami U, Letvin NL, Koralnik IJ. JCV-specific cellular immune response correlates with a favorable clinical outcome in HIV-infected individuals with progressive multifocal leukoencephalopathy. J Neurovirol. 2001 Aug; 7(4):318-22. PMID: 11517410.
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    188. Pfister LA, Letvin NL, Koralnik IJ. JC virus regulatory region tandem repeats in plasma and central nervous system isolates correlate with poor clinical outcome in patients with progressive multifocal leukoencephalopathy. J Virol. 2001 Jun; 75(12):5672-6. PMID: 11356975.
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    189. Koralnik IJ, Du Pasquier RA, Letvin NL. JC virus-specific cytotoxic T lymphocytes in individuals with progressive multifocal leukoencephalopathy. J Virol. 2001 Apr; 75(7):3483-7. PMID: 11238876.
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    190. Kempf W, Kadin ME, Kutzner H, Lord CL, Burg G, Letvin NL, Koralnik IJ. Lymphomatoid papulosis and human herpesviruses--A PCR-based evaluation for the presence of human herpesvirus 6, 7 and 8 related herpesviruses. J Cutan Pathol. 2001 Jan; 28(1):29-33. PMID: 11168749.
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    191. Kempf W, Margolin DH, Dezube BJ, Kadin ME, Letvin NL, Koralnik IJ. Clinicopathological characterization of an HIV-2-infected individual with two clonally unrelated primary lymphomas. Am J Hematol. 2000 Dec; 65(4):302-6. PMID: 11074559.
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    192. Koralnik IJ, Schmitz JE, Lifton MA, Forman MA, Letvin NL. Detection of JC virus DNA in peripheral blood cell subpopulations of HIV-1-infected individuals. J Neurovirol. 1999 Aug; 5(4):430-5. PMID: 10463865.
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    193. Koralnik IJ, Boden D, Mai VX, Lord CI, Letvin NL. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology. 1999 Jan 15; 52(2):253-60. PMID: 9932940.
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    194. Burquier V, Koralnik IJ, Vibert D, Burkhard P, Beaumanoir A, Jallon P, Mayer E, Hirschel B. [Effect of antiretroviral treatment on early electroencephalographic and otoneurologic manifestations in HIV infection and prognostic importance of verified perturbations]. Neurophysiol Clin. 1997 Dec; 27(6):508-19. PMID: 9488974.
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    195. Cereseto A, Berneman Z, Koralnik I, Vaughn J, Franchini G, Klotman ME. Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines. Leukemia. 1997 Jun; 11(6):866-70. PMID: 9177442.
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    196. Lagreze WD, Warner JE, Zamani AA, Gouras GK, Koralnik IJ, Bienfang DC. Mesencephalic clefts with associated eye movement disorders. Arch Ophthalmol. 1996 Apr; 114(4):429-32. PMID: 8602780.
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    197. Koralnik IJ, Mulloy JC, Andresson T, Fullen J, Franchini G. Mapping of the intermolecular association of human T cell leukaemia/lymphotropic virus type I p12I and the vacuolar H+-ATPase 16 kDa subunit protein. J Gen Virol. 1995 Aug; 76 ( Pt 8):1909-16. PMID: 7636472.
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    198. Koralnik IJ, Boeri E, Saxinger WC, Monico AL, Fullen J, Gessain A, Guo HG, Gallo RC, Markham P, Kalyanaraman V, et al. Phylogenetic associations of human and simian T-cell leukemia/lymphotropic virus type I strains: evidence for interspecies transmission. J Virol. 1994 Apr; 68(4):2693-707. PMID: 7908063.
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    199. Gessain A, Koralnik IJ, Fullen J, Boeri E, Mora C, Blank A, Salazar-Grueso EF, Kaplan J, Saxinger WC, Davidson M, et al. Phylogenetic study of ten new HTLV-I strains from the Americas. AIDS Res Hum Retroviruses. 1994 Jan; 10(1):103-6. PMID: 7514013.
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    200. Franchini G, Mulloy JC, Koralnik IJ, Lo Monico A, Sparkowski JJ, Andresson T, Goldstein DJ, Schlegel R. The human T-cell leukemia/lymphotropic virus type I p12I protein cooperates with the E5 oncoprotein of bovine papillomavirus in cell transformation and binds the 16-kilodalton subunit of the vacuolar H+ ATPase. J Virol. 1993 Dec; 67(12):7701-4. PMID: 8230493.
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    201. Koralnik IJ, Fullen J, Franchini G. The p12I, p13II, and p30II proteins encoded by human T-cell leukemia/lymphotropic virus type I open reading frames I and II are localized in three different cellular compartments. J Virol. 1993 Apr; 67(4):2360-6. PMID: 8445734.
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    202. Koralnik IJ, Hirschel B. EEG findings in asymptomatic HIV. Neurology. 1993 Mar; 43(3 Pt 1):635-6. PMID: 8451023.
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    203. Koralnik IJ, Lemp JF, Gallo RC, Franchini G. In vitro infection of human macrophages by human T-cell leukemia/lymphotropic virus type I (HTLV-I). AIDS Res Hum Retroviruses. 1992 Nov; 8(11):1845-9. PMID: 1489573.
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    204. Koralnik IJ, Gessain A, Klotman ME, Lo Monico A, Berneman ZN, Franchini G. Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8813-7. PMID: 1528897.
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    205. Koralnik IJ, Hirschel B. [Neurological complication of human immunodeficiency virus infection]. Presse Med. 1991 Jun 22; 20(24):1129-35. PMID: 1649474.
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    206. Hausler R, Vibert D, Koralnik IJ, Hirschel B. Neuro-otological manifestations in different stages of HIV infection. Acta Otolaryngol Suppl. 1991; 481:515-21. PMID: 1927460.
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    207. Koralnik IJ, Beaumanoir A, H?usler R, Kohler A, Safran AB, Delacoux R, Vibert D, Mayer E, Burkhard P, Nahory A, et al. A controlled study of early neurologic abnormalities in men with asymptomatic human immunodeficiency virus infection. N Engl J Med. 1990 Sep 27; 323(13):864-70. PMID: 1975637.
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