"Leukocyte Rolling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Descriptor ID |
D036904
|
MeSH Number(s) |
G04.198.424.233.500
|
Concept/Terms |
Leukocyte Rolling- Leukocyte Rolling
- Rolling, Leukocyte
- Leucocyte Rolling
- Rolling, Leucocyte
|
Below are MeSH descriptors whose meaning is more general than "Leukocyte Rolling".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Rolling".
This graph shows the total number of publications written about "Leukocyte Rolling" by people in this website by year, and whether "Leukocyte Rolling" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocyte Rolling" by people in Profiles.
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CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis. Blood. 2008 Dec 15; 112(13):4999-5006.
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Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis. Arthritis Rheum. 2005 Oct; 52(10):3269-78.
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Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? Exp Dermatol. 2005 Jan; 14(1):70-80.