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Martha C. Morris

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Digestive Diseases and Nutrition
Address1645 W. Jackson Blvd.
Chicago IL 60612
Phone312-942-3223
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    Collapse Overview 
    Collapse overview
    Additional appointments:
    Professor and Director, Section on Nutrition and Nutritional Epidemiology
    Department of Medicine
    Assistant Provost for Community Research
    Rush University Medical Center

    Overview:
    I co-direct the Rush site Institute for Translation Medicine (ITM) Community and Collaboration Cluster. My research studies risk factors in the development of Alzheimer’s disease and other health problems of older persons, and in particular, how nutrition relates to these conditions. I have published findings on the relations of diet patterns, antioxidant nutrients, dietary fats, and the B-vitamins to these conditions, and am the lead creator of the MIND diet for healthy brain aging. I have a long history of NIH and other funding to examine dietary risk factors of Alzheimer’s disease among 10,000 African American and Caucasian participants of the Chicago Health and Aging Project and the relations of dietary components and patterns to neuropathology and neurologic diseases among 1,200 Chicago participants of the Memory and Aging Project. I am also the Principal Investigator of a multi-center randomized trial of the MIND diet to prevent Alzheimer’s disease.

    My ORCID is 0000-0002-5355-4918.
    My Scopus ID is 57193537989.
    NIH COMMONS: martha_clare_morris

    Education:
    BA, 1977 University of Iowa
    MA, 1980 University of Iowa
    ScD, 1992 Harvard T.H. Chan of Public Health


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cornelis MC, Wang Y, Holland T, Agarwal P, Weintraub S, Morris MC. Age and cognitive decline in the UK Biobank. PLoS One. 2019; 14(3):e0213948. PMID: 30883587.
      View in: PubMed
    2. Ayton S, Wang Y, Diouf I, Schneider JA, Brockman J, Morris MC, Bush AI. Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology. Mol Psychiatry. 2019 Feb 18. PMID: 30778133.
      View in: PubMed
    3. Babulal GM, Quiroz YT, Albensi BC, Arenaza-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, Bell J, Bowman GL, Brickman AM, Chételat G, Ciro C, Cohen AD, Dilworth-Anderson P, Dodge HH, Dreux S, Edland S, Esbensen A, Evered L, Ewers M, Fargo KN, Fortea J, Gonzalez H, Gustafson DR, Head E, Hendrix JA, Hofer SM, Johnson LA, Jutten R, Kilborn K, Lanctôt KL, Manly JJ, Martins RN, Mielke MM, Morris MC, Murray ME, Oh ES, Parra MA, Rissman RA, Roe CM, Santos OA, Scarmeas N, Schneider LS, Schupf N, Sikkes S, Snyder HM, Sohrabi HR, Stern Y, Strydom A, Tang Y, Terrera GM, Teunissen C, Melo van Lent D, Weinborn M, Wesselman L, Wilcock DM, Zetterberg H, O'Bryant SE. Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need. Alzheimers Dement. 2019 Feb; 15(2):292-312. PMID: 30555031.
      View in: PubMed
    4. Agarwal P, Wang Y, Buchman AS, Bennett DA, Morris MC. Dietary Patterns and Self-reported Incident Disability in Elderly. J Gerontol A Biol Sci Med Sci. 2018 Sep 21. PMID: 30247552.
      View in: PubMed
    5. Samieri C, Morris MC, Bennett DA, Berr C, Amouyel P, Dartigues JF, Tzourio C, Chasman DI, Grodstein F. Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons. Am J Epidemiol. 2018 May 01; 187(5):933-940. PMID: 29053784.
      View in: PubMed
    6. Morris MC, Wang Y, Barnes LL, Bennett DA, Dawson-Hughes B, Booth SL. Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study. Neurology. 2018 Jan 16; 90(3):e214-e222. PMID: 29263222.
      View in: PubMed
    7. Morris MC. Caffeine Intake and Dementia Risk-A Health Benefit From One of Life's Simple Pleasures? J Gerontol A Biol Sci Med Sci. 2016 12; 71(12):1595. PMID: 27678291.
      View in: PubMed
    8. Pistollato F, Ohayon EL, Lam A, Langley GR, Novak TJ, Pamies D, Perry G, Trushina E, Williams RS, Roher AE, Hartung T, Harnad S, Barnard N, Morris MC, Lai MC, Merkley R, Chandrasekera PC. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. Oncotarget. 2016 Jun 28; 7(26):38999-39016. PMID: 27229915.
      View in: PubMed
    9. van de Rest O, Wang Y, Barnes LL, Tangney C, Bennett DA, Morris MC. APOE e4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline. Neurology. 2016 05 31; 86(22):2063-70. PMID: 27164694.
      View in: PubMed
    10. Morris MC. Nutrition and risk of dementia: overview and methodological issues. Ann N Y Acad Sci. 2016 03; 1367(1):31-7. PMID: 27116239.
      View in: PubMed
    11. Morris MC, Brockman J, Schneider JA, Wang Y, Bennett DA, Tangney CC, van de Rest O. Association of Seafood Consumption, Brain Mercury Level, and APOE e4 Status With Brain Neuropathology in Older Adults. JAMA. 2016 Feb 02; 315(5):489-97. PMID: 26836731.
      View in: PubMed
    12. Morris MC, Tangney CC, Wang Y, Sacks FM, Barnes LL, Bennett DA, Aggarwal NT. MIND diet slows cognitive decline with aging. Alzheimers Dement. 2015 Sep; 11(9):1015-22. PMID: 26086182.
      View in: PubMed
    13. Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT. MIND diet associated with reduced incidence of Alzheimer's disease. Alzheimers Dement. 2015 Sep; 11(9):1007-14. PMID: 25681666.
      View in: PubMed
    14. Barnes JL, Tian M, Edens NK, Morris MC. Consideration of nutrient levels in studies of cognitive decline. Nutr Rev. 2014 Nov; 72(11):707-19. PMID: 25323849.
      View in: PubMed
    15. Tangney CC, Li H, Wang Y, Barnes L, Schneider JA, Bennett DA, Morris MC. Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons. Neurology. 2014 Oct 14; 83(16):1410-6. PMID: 25230996.
      View in: PubMed
    16. Morris MC, Tangney CC. Dietary fat composition and dementia risk. Neurobiol Aging. 2014 Sep; 35 Suppl 2:S59-64. PMID: 24970568.
      View in: PubMed
    17. Barnard ND, Bush AI, Ceccarelli A, Cooper J, de Jager CA, Erickson KI, Fraser G, Kesler S, Levin SM, Lucey B, Morris MC, Squitti R. Dietary and lifestyle guidelines for the prevention of Alzheimer's disease. Neurobiol Aging. 2014 Sep; 35 Suppl 2:S74-8. PMID: 24913896.
      View in: PubMed
    18. Morris MC, Schneider JA, Li H, Tangney CC, Nag S, Bennett DA, Honer WG, Barnes LL. Brain tocopherols related to Alzheimer's disease neuropathology in humans. Alzheimers Dement. 2015 Jan; 11(1):32-9. PMID: 24589434.
      View in: PubMed
    19. Evans DA, Morris MC, Rajan KB. Vitamin E, memantine, and Alzheimer disease. JAMA. 2014 Jan 01; 311(1):29-30. PMID: 24381966.
      View in: PubMed
    20. Arfanakis K, Fleischman DA, Grisot G, Barth CM, Varentsova A, Morris MC, Barnes LL, Bennett DA. Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition. PLoS One. 2013; 8(8):e73107. PMID: 23991174.
      View in: PubMed
    21. Staffileno BA, Tangney CC, Wilbur J, Marquez DX, Fogg L, Manning A, Bustamante EE, Morris MC. Dietary approaches to stop hypertension patterns in older Latinos with or at risk for hypertension. J Cardiovasc Nurs. 2013 Jul-Aug; 28(4):338-47. PMID: 22722473.
      View in: PubMed
    22. Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A. CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nat Neurosci. 2013 Jul; 16(7):848-50. PMID: 23708142.
      View in: PubMed
    23. Wilbur J, Marquez DX, Fogg L, Wilson RS, Staffileno BA, Hoyem RL, Morris MC, Bustamante EE, Manning AF. The relationship between physical activity and cognition in older Latinos. J Gerontol B Psychol Sci Soc Sci. 2012 Sep; 67(5):525-34. PMID: 22321957.
      View in: PubMed
    24. Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA. Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol. 2012 Feb; 71(2):258-66. PMID: 22367997.
      View in: PubMed
    25. Cunnane SC, Schneider JA, Tangney C, Tremblay-Mercier J, Fortier M, Bennett DA, Morris MC. Plasma and brain fatty acid profiles in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis. 2012; 29(3):691-7. PMID: 22466064.
      View in: PubMed
    26. Morris MC. Nutritional determinants of cognitive aging and dementia. Proc Nutr Soc. 2012 Feb; 71(1):1-13. PMID: 22067138.
      View in: PubMed
    27. Morris MC, Tangney CC. A potential design flaw of randomized trials of vitamin supplements. JAMA. 2011 Apr 06; 305(13):1348-9. PMID: 21467288.
      View in: PubMed
    28. Hensley K, Barnes LL, Christov A, Tangney C, Honer WG, Schneider JA, Bennett DA, Morris MC. Analysis of postmortem ventricular cerebrospinal fluid from patients with and without dementia indicates association of vitamin E with neuritic plaques and specific measures of cognitive performance. J Alzheimers Dis. 2011; 24(4):767-74. PMID: 21321395.
      View in: PubMed
    29. Tangney CC, Kwasny MJ, Li H, Wilson RS, Evans DA, Morris MC. Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population. Am J Clin Nutr. 2011 Mar; 93(3):601-7. PMID: 21177796.
      View in: PubMed
    30. Fleischman DA, Arfanakis K, Kelly JF, Rajendran N, Buchman AS, Morris MC, Barnes LL, Bennett DA. Regional brain cortical thinning and systemic inflammation in older persons without dementia. J Am Geriatr Soc. 2010 Sep; 58(9):1823-5. PMID: 20863359.
      View in: PubMed
    31. Morris MC, Tangney CC. Diet and prevention of Alzheimer disease. JAMA. 2010 Jun 23; 303(24):2519-20. PMID: 20578272.
      View in: PubMed
    32. Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr. 2010 Aug; 92(2):330-5. PMID: 20519557.
      View in: PubMed
    33. Harris WS, Mozaffarian D, Lefevre M, Toner CD, Colombo J, Cunnane SC, Holden JM, Klurfeld DM, Morris MC, Whelan J. Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids. J Nutr. 2009 Apr; 139(4):804S-19S. PMID: 19244379.
      View in: PubMed
    34. Tangney CC, Tang Y, Evans DA, Morris MC. Biochemical indicators of vitamin B12 and folate insufficiency and cognitive decline. Neurology. 2009 Jan 27; 72(4):361-7. PMID: 19171834.
      View in: PubMed
    35. Morris MC, Tangney CC. Is dietary intake of folate too low? Lancet. 2007 Jan 20; 369(9557):166-7. PMID: 17240266.
      View in: PubMed
    36. Morris MC. Docosahexaenoic acid and Alzheimer disease. Arch Neurol. 2006 Nov; 63(11):1527-8. PMID: 17101820.
      View in: PubMed
    37. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS. Associations of vegetable and fruit consumption with age-related cognitive change. Neurology. 2006 Oct 24; 67(8):1370-6. PMID: 17060562.
      View in: PubMed
    38. Quander CR, Morris MC, Mendes de Leon CF, Bienias JL, Evans DA. Association of fecal incontinence with physical disability and impaired cognitive function. Am J Gastroenterol. 2006 Nov; 101(11):2588-93. PMID: 16952285.
      View in: PubMed
    39. Morris MC, Evans DA, Tangney CC, Bienias JL, Schneider JA, Wilson RS, Scherr PA. Dietary copper and high saturated and trans fat intakes associated with cognitive decline. Arch Neurol. 2006 Aug; 63(8):1085-8. PMID: 16908733.
      View in: PubMed
    40. Morris MC, Schneider JA, Tangney CC. Thoughts on B-vitamins and dementia. J Alzheimers Dis. 2006 Aug; 9(4):429-33. PMID: 16917152.
      View in: PubMed
    41. Mendes de Leon CF, Hansberry MR, Bienias JL, Morris MC, Evans DA. Relative weight and mobility: a longitudinal study in a biracial population of older adults. Ann Epidemiol. 2006 Oct; 16(10):770-6. PMID: 16882461.
      View in: PubMed
    42. Morris MC, Evans DA, Schneider JA, Tangney CC, Bienias JL, Aggarwal NT. Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease. J Alzheimers Dis. 2006 Aug; 9(4):435-43. PMID: 16917153.
      View in: PubMed
    43. Schneider JA, Tangney CC, Morris MC. Folic acid and cognition in older persons. Expert Opin Drug Saf. 2006 Jul; 5(4):511-22. PMID: 16774490.
      View in: PubMed
    44. Morris MC. Diet and Alzheimer's disease: meeting the challenges. J Nutr Health Aging. 2006 May-Jun; 10(3):204. PMID: 16729387.
      View in: PubMed
    45. Aggarwal NT, Bienias JL, Bennett DA, Wilson RS, Morris MC, Schneider JA, Shah RC, Evans DA. The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population. Neuroepidemiology. 2006; 26(3):140-6. PMID: 16493200.
      View in: PubMed
    46. Sturman MT, Morris MC, Mendes de Leon CF, Bienias JL, Wilson RS, Evans DA. Physical activity, cognitive activity, and cognitive decline in a biracial community population. Arch Neurol. 2005 Nov; 62(11):1750-4. PMID: 16286550.
      View in: PubMed
    47. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS. Fish consumption and cognitive decline with age in a large community study. Arch Neurol. 2005 Dec; 62(12):1849-53. PMID: 16216930.
      View in: PubMed
    48. Morris MC, Evans DA, Bienias JL, Tangney CC, Hebert LE, Scherr PA, Schneider JA. Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch Neurol. 2005 Apr; 62(4):641-5. PMID: 15824266.
      View in: PubMed
    49. Quander CR, Morris MC, Melson J, Bienias JL, Evans DA. Prevalence of and factors associated with fecal incontinence in a large community study of older individuals. Am J Gastroenterol. 2005 Apr; 100(4):905-9. PMID: 15784039.
      View in: PubMed
    50. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb; 81(2):508-14. PMID: 15699242.
      View in: PubMed
    51. Wilson RS, Bennett DA, Mendes de Leon CF, Bienias JL, Morris MC, Evans DA. Distress proneness and cognitive decline in a population of older persons. Psychoneuroendocrinology. 2005 Jan; 30(1):11-7. PMID: 15358438.
      View in: PubMed
    52. McCann JJ, Hebert LE, Bienias JL, Morris MC, Evans DA. Predictors of beginning and ending caregiving during a 3-year period in a biracial community population of older adults. Am J Public Health. 2004 Oct; 94(10):1800-6. PMID: 15451753.
      View in: PubMed
    53. Morris MC, Evans DA, Bienias JL, Scherr PA, Tangney CC, Hebert LE, Bennett DA, Wilson RS, Aggarwal N. Dietary niacin and the risk of incident Alzheimer's disease and of cognitive decline. J Neurol Neurosurg Psychiatry. 2004 Aug; 75(8):1093-9. PMID: 15258207.
      View in: PubMed
    54. Morris MC, Evans DA, Bienias JL, Tangney CC, Wilson RS. Dietary fat intake and 6-year cognitive change in an older biracial community population. Neurology. 2004 May 11; 62(9):1573-9. PMID: 15136684.
      View in: PubMed
    55. Tangney CC, Bienias JL, Evans DA, Morris MC. Reasonable estimates of serum vitamin E, vitamin C, and beta-cryptoxanthin are obtained with a food frequency questionnaire in older black and white adults. J Nutr. 2004 Apr; 134(4):927-34. PMID: 15051849.
      View in: PubMed
    56. Morris MC. Diet and Alzheimer's disease: what the evidence shows. MedGenMed. 2004 Jan 15; 6(1):48. PMID: 15208559.
      View in: PubMed
    57. Morris MC, Tangney CC, Bienias JL, Evans DA, Wilson RS. Validity and reproducibility of a food frequency questionnaire by cognition in an older biracial sample. Am J Epidemiol. 2003 Dec 15; 158(12):1213-7. PMID: 14652307.
      View in: PubMed
    58. Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol. 2003 Jul; 60(7):940-6. PMID: 12873849.
      View in: PubMed
    59. Evans DA, Bennett DA, Wilson RS, Bienias JL, Morris MC, Scherr PA, Hebert LE, Aggarwal N, Beckett LA, Joglekar R, Berry-Kravis E, Schneider J. Incidence of Alzheimer disease in a biracial urban community: relation to apolipoprotein E allele status. Arch Neurol. 2003 Feb; 60(2):185-9. PMID: 12580702.
      View in: PubMed
    60. Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Schneider J, Wilson RS. Dietary fats and the risk of incident Alzheimer disease. Arch Neurol. 2003 Feb; 60(2):194-200. PMID: 12580703.
      View in: PubMed
    61. Morris MC, Evans DA, Bienias JL, Tangney CC, Wilson RS. Vitamin E and cognitive decline in older persons. Arch Neurol. 2002 Jul; 59(7):1125-32. PMID: 12117360.
      View in: PubMed
    62. Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA. 2002 Jun 26; 287(24):3230-7. PMID: 12076219.
      View in: PubMed
    63. Morris MC, Scherr PA, Hebert LE, Bennett DA, Wilson RS, Glynn RJ, Evans DA. Association between blood pressure and cognitive function in a biracial community population of older persons. Neuroepidemiology. 2002 May-Jun; 21(3):123-30. PMID: 12006775.
      View in: PubMed
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