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This is a "connection" page, showing publications co-authored by Ali Keshavarzian and Christopher Forsyth.
Ali Keshavarzian
Connection Strength
12.717
Christopher Forsyth
  1. Alcohol use disorder as a potential risk factor for COVID-19 severity: A narrative review. Alcohol Clin Exp Res. 2022 11; 46(11):1930-1943.
    View in: PubMed
    Score: 0.838
  2. The SARS-CoV-2 S1 Spike Protein Promotes MAPK and NF-kB Activation in Human Lung Cells and Inflammatory Cytokine Production in Human Lung and Intestinal Epithelial Cells. Microorganisms. 2022 Oct 10; 10(10).
    View in: PubMed
    Score: 0.832
  3. Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate. Alcohol Clin Exp Res. 2017 Dec; 41(12):2100-2113.
    View in: PubMed
    Score: 0.592
  4. Circadian rhythms, alcohol and gut interactions. Alcohol. 2015 Jun; 49(4):389-98.
    View in: PubMed
    Score: 0.481
  5. Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness. Redox Biol. 2014; 3:40-6.
    View in: PubMed
    Score: 0.479
  6. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15; 305(2):G185-95.
    View in: PubMed
    Score: 0.433
  7. Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. PLoS One. 2011; 6(12):e28032.
    View in: PubMed
    Score: 0.392
  8. Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability. Alcohol Clin Exp Res. 2011 Sep; 35(9):1635-43.
    View in: PubMed
    Score: 0.376
  9. Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cells. Alcohol Clin Exp Res. 2010 Jan; 34(1):19-31.
    View in: PubMed
    Score: 0.339
  10. Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis. Alcohol. 2009 Mar; 43(2):163-72.
    View in: PubMed
    Score: 0.324
  11. Regulation of oxidant-induced intestinal permeability by metalloprotease-dependent epidermal growth factor receptor signaling. J Pharmacol Exp Ther. 2007 Apr; 321(1):84-97.
    View in: PubMed
    Score: 0.279
  12. An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants. Nat Commun. 2023 02 18; 14(1):926.
    View in: PubMed
    Score: 0.213
  13. Abnormal intestinal milieu in posttraumatic stress disorder is not impacted by treatment that improves symptoms. Am J Physiol Gastrointest Liver Physiol. 2022 08 01; 323(2):G61-G70.
    View in: PubMed
    Score: 0.203
  14. Gut microbial metabolites in Parkinson's disease: Association with lifestyle, disease characteristics, and treatment status. Neurobiol Dis. 2022 08; 170:105780.
    View in: PubMed
    Score: 0.203
  15. Gut-Brain Communication in Parkinson's Disease: Enteroendocrine Regulation by GLP-1. Curr Neurol Neurosci Rep. 2022 07; 22(7):335-342.
    View in: PubMed
    Score: 0.203
  16. Intestinal Barrier Dysfunction in the Absence of Systemic Inflammation Fails to Exacerbate Motor Dysfunction and Brain Pathology in a Mouse Model of Parkinson's Disease. Front Neurol. 2022; 13:882628.
    View in: PubMed
    Score: 0.202
  17. Disrupted Circadian Rest-Activity Cycles in Inflammatory Bowel Disease Are Associated With Aggressive Disease Phenotype, Subclinical Inflammation, and Dysbiosis. Front Med (Lausanne). 2021; 8:770491.
    View in: PubMed
    Score: 0.198
  18. Deep nasal sinus cavity microbiota dysbiosis in Parkinson's disease. NPJ Parkinsons Dis. 2021 Dec 08; 7(1):111.
    View in: PubMed
    Score: 0.196
  19. Attenuated Postprandial GLP-1 Response in Parkinson's Disease. Front Neurosci. 2021; 15:660942.
    View in: PubMed
    Score: 0.190
  20. Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease. PLoS One. 2021; 16(3):e0240342.
    View in: PubMed
    Score: 0.186
  21. Disrupted diurnal oscillation of gut-derived Short chain fatty acids in shift workers drinking alcohol: Possible mechanism for loss of resiliency of intestinal barrier in disrupted circadian host. Transl Res. 2020 07; 221:97-109.
    View in: PubMed
    Score: 0.176
  22. Diet in Parkinson's Disease: Critical Role for the Microbiome. Front Neurol. 2019; 10:1245.
    View in: PubMed
    Score: 0.171
  23. Circadian rhythms: a regulator of gastrointestinal health and dysfunction. Expert Rev Gastroenterol Hepatol. 2019 May; 13(5):411-424.
    View in: PubMed
    Score: 0.163
  24. Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiol Dis. 2020 02; 135:104352.
    View in: PubMed
    Score: 0.160
  25. Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice. Gut. 2019 05; 68(5):829-843.
    View in: PubMed
    Score: 0.160
  26. Circadian Mechanisms in Alcohol Use Disorder and Tissue Injury. Alcohol Clin Exp Res. 2018 04; 42(4):668-677.
    View in: PubMed
    Score: 0.151
  27. Dietary Fiber Treatment Corrects the Composition of Gut Microbiota, Promotes SCFA Production, and Suppresses Colon Carcinogenesis. Genes (Basel). 2018 Feb 16; 9(2).
    View in: PubMed
    Score: 0.151
  28. Diurnal variations in intestinal barrier integrity and liver pathology in mice: implications for alcohol binge. Am J Physiol Gastrointest Liver Physiol. 2018 01 01; 314(1):G131-G141.
    View in: PubMed
    Score: 0.148
  29. Alcohol and Gut-Derived Inflammation. Alcohol Res. 2017; 38(2):163-171.
    View in: PubMed
    Score: 0.139
  30. Light/Dark Shifting Promotes Alcohol-Induced Colon Carcinogenesis: Possible Role of Intestinal Inflammatory Milieu and Microbiota. Int J Mol Sci. 2016 Dec 02; 17(12).
    View in: PubMed
    Score: 0.139
  31. Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking. Am J Physiol Gastrointest Liver Physiol. 2016 07 01; 311(1):G192-201.
    View in: PubMed
    Score: 0.134
  32. Lower Neighborhood Socioeconomic Status Associated with Reduced Diversity of the Colonic Microbiota in Healthy Adults. PLoS One. 2016; 11(2):e0148952.
    View in: PubMed
    Score: 0.131
  33. The Circadian Clock Mutation Promotes Intestinal Dysbiosis. Alcohol Clin Exp Res. 2016 Feb; 40(2):335-47.
    View in: PubMed
    Score: 0.131
  34. Alcohol and the Intestine. Biomolecules. 2015 Oct 15; 5(4):2573-88.
    View in: PubMed
    Score: 0.128
  35. The Role of miR-212 and iNOS in Alcohol-Induced Intestinal Barrier Dysfunction and Steatohepatitis. Alcohol Clin Exp Res. 2015 Sep; 39(9):1632-41.
    View in: PubMed
    Score: 0.126
  36. Colonic bacterial composition in Parkinson's disease. Mov Disord. 2015 Sep; 30(10):1351-60.
    View in: PubMed
    Score: 0.126
  37. Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 15; 308(12):G1004-11.
    View in: PubMed
    Score: 0.124
  38. Alcohol induced alterations to the human fecal VOC metabolome. PLoS One. 2015; 10(3):e0119362.
    View in: PubMed
    Score: 0.123
  39. Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability. Clin Chim Acta. 2015 Mar 10; 442:24-32.
    View in: PubMed
    Score: 0.122
  40. The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota. Alcohol Res. 2015; 37(2):223-36.
    View in: PubMed
    Score: 0.121
  41. The role of miRNAs in alcohol-induced endotoxemia, dysfunction of mucosal immunity, and gut leakiness. Alcohol Clin Exp Res. 2014 Sep; 38(9):2331-4.
    View in: PubMed
    Score: 0.119
  42. Circadian disorganization alters intestinal microbiota. PLoS One. 2014; 9(5):e97500.
    View in: PubMed
    Score: 0.116
  43. The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome. PLoS One. 2013; 8(11):e81163.
    View in: PubMed
    Score: 0.112
  44. Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation. PLoS One. 2013; 8(6):e67102.
    View in: PubMed
    Score: 0.109
  45. Ethanol-induced mast cell-mediated inflammation leads to increased susceptibility of intestinal tumorigenesis in the APC ?468 min mouse model of colon cancer. Alcohol Clin Exp Res. 2013 Jan; 37 Suppl 1:E199-208.
    View in: PubMed
    Score: 0.106
  46. Circadian disruption: potential implications in inflammatory and metabolic diseases associated with alcohol. Alcohol Res. 2013; 35(1):87-96.
    View in: PubMed
    Score: 0.106
  47. New molecular insights into inflammatory bowel disease-induced diarrhea. Expert Rev Gastroenterol Hepatol. 2011 Oct; 5(5):615-25.
    View in: PubMed
    Score: 0.097
  48. Is moderate red wine consumption safe in inactive inflammatory bowel disease? Digestion. 2011; 84(3):238-44.
    View in: PubMed
    Score: 0.096
  49. Role of intestinal circadian genes in alcohol-induced gut leakiness. Alcohol Clin Exp Res. 2011 Jul; 35(7):1305-14.
    View in: PubMed
    Score: 0.094
  50. Effects of aspirin on gastroduodenal permeability in alcoholics and controls. Alcohol. 2010 Aug; 44(5):447-56.
    View in: PubMed
    Score: 0.089
  51. The role of matrix metalloproteinases in intestinal epithelial wound healing during normal and inflammatory states. J Surg Res. 2011 Jun 15; 168(2):315-24.
    View in: PubMed
    Score: 0.087
  52. Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damage. Alcohol Clin Exp Res. 2009 Jul; 33(7):1220-30.
    View in: PubMed
    Score: 0.082
  53. Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage. J Pharmacol Exp Ther. 2009 Jun; 329(3):952-8.
    View in: PubMed
    Score: 0.081
  54. Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats. J Hepatol. 2009 Mar; 50(3):538-47.
    View in: PubMed
    Score: 0.080
  55. Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease. Alcohol Clin Exp Res. 2008 Feb; 32(2):355-64.
    View in: PubMed
    Score: 0.075
  56. Phosphodiesterase 4 inhibitors and inflammatory bowel disease: emerging therapies in inflammatory bowel disease. Expert Opin Investig Drugs. 2007 Sep; 16(9):1489-506.
    View in: PubMed
    Score: 0.073
  57. theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. J Pharmacol Exp Ther. 2005 Jun; 313(3):962-82.
    View in: PubMed
    Score: 0.062
  58. Gut microbiome dysbiosis is associated with lumbar degenerative spondylolisthesis in symptomatic patients. JOR Spine. 2024 Dec; 7(4):e70005.
    View in: PubMed
    Score: 0.060
  59. Critical role of the atypical {lambda} isoform of protein kinase C (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium. J Pharmacol Exp Ther. 2005 Feb; 312(2):458-71.
    View in: PubMed
    Score: 0.059
  60. Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis. Inflamm Bowel Dis. 2023 03 01; 29(3):444-457.
    View in: PubMed
    Score: 0.053
  61. The Versatility and Diagnostic Potential of VOC Profiling for Noninfectious Diseases. BME Front. 2023; 4:0002.
    View in: PubMed
    Score: 0.053
  62. Colon epithelial cell-specific Bmal1 deletion impairs bone formation in mice. Bone. 2023 03; 168:116650.
    View in: PubMed
    Score: 0.053
  63. Impact of alcohol-induced intestinal microbiota dysbiosis in a rodent model of Alzheimer's disease. Front Aging. 2022; 3:916336.
    View in: PubMed
    Score: 0.051
  64. Dietary Regulation of Gut-Brain Axis in Alzheimer's Disease: Importance of Microbiota Metabolites. Front Neurosci. 2021; 15:736814.
    View in: PubMed
    Score: 0.049
  65. Corrigendum: Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 Patients. Front Immunol. 2021; 12:779064.
    View in: PubMed
    Score: 0.048
  66. Erratum for Adeniji et al., "COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions". mBio. 2021 Jun 29; 12(3):e0124421.
    View in: PubMed
    Score: 0.047
  67. Circadian misalignment by environmental light/dark shifting causes circadian disruption in colon. PLoS One. 2021; 16(6):e0251604.
    View in: PubMed
    Score: 0.047
  68. COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions. mBio. 2021 04 20; 12(2).
    View in: PubMed
    Score: 0.047
  69. The gut microbiota may be a novel pathogenic mechanism in loosening of orthopedic implants in rats. FASEB J. 2020 11; 34(11):14302-14317.
    View in: PubMed
    Score: 0.045
  70. Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis. Cell Mol Gastroenterol Hepatol. 2020; 9(2):219-237.
    View in: PubMed
    Score: 0.042
  71. Gut bacterial composition in a mouse model of Parkinson's disease. Benef Microbes. 2018 Sep 18; 9(5):799-814.
    View in: PubMed
    Score: 0.039
  72. Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging. Ann N Y Acad Sci. 2019 04; 1442(1):48-60.
    View in: PubMed
    Score: 0.039
  73. Corrigendum to "Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain" [GENE 655 (2018) 1-12]. Gene. 2019 01 05; 680:105.
    View in: PubMed
    Score: 0.039
  74. Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain. Gene. 2018 May 20; 655:1-12.
    View in: PubMed
    Score: 0.038
  75. The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia. Cell Rep. 2018 01 09; 22(2):523-534.
    View in: PubMed
    Score: 0.037
  76. Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats. PLoS One. 2018; 13(1):e0190078.
    View in: PubMed
    Score: 0.037
  77. Alcohol Injury Damages Intestinal Stem Cells. Alcohol Clin Exp Res. 2017 04; 41(4):727-734.
    View in: PubMed
    Score: 0.035
  78. Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet. Sci Rep. 2015 Nov 20; 5:16896.
    View in: PubMed
    Score: 0.032
  79. Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease. Front Neurosci. 2015; 9:306.
    View in: PubMed
    Score: 0.032
  80. HIV-associated mucosal gene expression: region-specific alterations. AIDS. 2015 Mar 13; 29(5):537-46.
    View in: PubMed
    Score: 0.031
  81. In vitro evaluation of intestinal epithelial TLR activation in preventing food allergic responses. Clin Immunol. 2014 Oct; 154(2):91-9.
    View in: PubMed
    Score: 0.029
  82. A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. PLoS Pathog. 2014 Feb; 10(2):e1003829.
    View in: PubMed
    Score: 0.029
  83. Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics. Front Immunol. 2014; 5:60.
    View in: PubMed
    Score: 0.029
  84. Chronic alcohol exposure renders epithelial cells vulnerable to bacterial infection. PLoS One. 2013; 8(1):e54646.
    View in: PubMed
    Score: 0.027
  85. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Alcohol Clin Exp Res. 2009 Oct; 33(10):1836-46.
    View in: PubMed
    Score: 0.021
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.