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Jochen Reiser

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Nephrology
Address1750 W. Harrison St
Chicago IL 60612
Phone312-942-6639
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    Collapse Overview 
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    My Scopus ID is 7004772937.
    My NIH COMMONS name is JREISER.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hahm E, Peev V, Reiser J. Extrarenal determinants of kidney filter function. Cell Tissue Res. 2017 May 30. PMID: 28560690.
      View in: PubMed
    2. Drechsler C, Hayek SS, Wei C, Sever S, Genser B, Krane V, Meinitzer A, März W, Wanner C, Reiser J. Soluble Urokinase Plasminogen Activator Receptor and Outcomes in Patients with Diabetes on Hemodialysis. Clin J Am Soc Nephrol. 2017 May 11. PMID: 28495863.
      View in: PubMed
    3. Reiser J, Lee HW, Gupta V, Altintas MM. A High-Content Screening Technology for Quantitatively Studying Podocyte Dynamics. Adv Chronic Kidney Dis. 2017 May; 24(3):183-188. PMID: 28501082.
      View in: PubMed
    4. Peev V, Hahm E, Reiser J. Unwinding focal segmental glomerulosclerosis. F1000Res. 2017; 6:466. PMID: 28491286.
      View in: PubMed
    5. Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB. Targeting mTOR Signaling Can Prevent the Progression of FSGS. J Am Soc Nephrol. 2017 Mar 07. PMID: 28270414.
      View in: PubMed
    6. Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest. 2017 Apr 03; 127(4):1271-1283. PMID: 28263189.
      View in: PubMed
    7. Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nat Med. 2017 Jan; 23(1):100-106. PMID: 27941791.
      View in: PubMed
    8. Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747. PMID: 27913625.
      View in: PubMed
    9. Müller-Deile J, Teng B, Schenk H, Haller H, Reiser J, Sever S, Schiffer M. Drugs targeting dynamin can restore cytoskeleton and focal contact alterations of urinary podocytes derived from patients with nephrotic syndrome. Ann Transl Med. 2016 Nov; 4(21):439. PMID: 27942530.
      View in: PubMed
    10. Gupta V, Reiser J. Stop that podocyte! Am J Physiol Renal Physiol. 2017 Feb 01; 312(2):F373-F374. PMID: 27760773.
      View in: PubMed
    11. Hamidi O, Reiser J, Hasler S. An Interferon-Induced Digital Vasculitis-Like Syndrome: A Case Report. Am J Ther. 2016 May-Jun; 23(3):e920-5. PMID: 24732907.
      View in: PubMed
    12. Yu H, Kistler A, Faridi MH, Meyer JO, Tryniszewska B, Mehta D, Yue L, Dryer S, Reiser J. Synaptopodin Limits TRPC6 Podocyte Surface Expression and Attenuates Proteinuria. J Am Soc Nephrol. 2016 Nov; 27(11):3308-3319. PMID: 27020855.
      View in: PubMed
    13. Hayek SS, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. N Engl J Med. 2016 Mar 03; 374(9):891. PMID: 26962914.
      View in: PubMed
    14. Reiser J, Altintas MM. Podocytes. F1000Res. 2016; 5. PMID: 26918173; PMCID: PMC4755401.
      View in: PubMed, PubMed Central
    15. Staeck O, Slowinski T, Lieker I, Wu K, Rudolph B, Schmidt D, Brakemeier S, Neumayer HH, Wei C, Reiser J, Budde K, Halleck F, Khadzhynov D. Recurrent Primary Focal Segmental Glomerulosclerosis Managed With Intensified Plasma Exchange and Concomitant Monitoring of Soluble Urokinase-Type Plasminogen Activator Receptor-Mediated Podocyte ß3-integrin Activation. Transplantation. 2015 Dec; 99(12):2593-7. PMID: 26371597; PMCID: PMC4900174 [Available on 12/01/16].
      View in: PubMed, PubMed Central
    16. Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. N Engl J Med. 2015 Nov 12; 373(20):1916-25. PMID: 26539835; PMCID: PMC4701036.
      View in: PubMed, PubMed Central
    17. Wei C, Sigdel TK, Sarwal MM, Reiser J. Circulating CD40 autoantibody and suPAR synergy drives glomerular injury. Ann Transl Med. 2015 Nov; 3(19):300. PMID: 26697460; PMCID: PMC4671868.
      View in: PubMed, PubMed Central
    18. Sever S, Reiser J. CD2AP, dendrin, and cathepsin L in the kidney. Am J Pathol. 2015 Nov; 185(11):3129-30. PMID: 26506476; PMCID: PMC4630172 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    19. Trachtman H, Vento S, Herreshoff E, Radeva M, Gassman J, Stein DT, Savin VJ, Sharma M, Reiser J, Wei C, Somers M, Srivastava T, Gipson DS. Efficacy of galactose and adalimumab in patients with resistant focal segmental glomerulosclerosis: report of the font clinical trial group. BMC Nephrol. 2015 Jul 22; 16:111. PMID: 26198842; PMCID: PMC4511259.
      View in: PubMed, PubMed Central
    20. Altintas MM, Reiser J. Bridges to cross, burn, and mend: cells of renin lineage as podocyte progenitors. Am J Physiol Renal Physiol. 2015 Sep 15; 309(6):F499-500. PMID: 26180240.
      View in: PubMed
    21. Forst AL, Olteanu VS, Mollet G, Wlodkowski T, Schaefer F, Dietrich A, Reiser J, Gudermann T, Mederos y Schnitzler M, Storch U. Podocyte Purinergic P2X4 Channels Are Mechanotransducers That Mediate Cytoskeletal Disorganization. J Am Soc Nephrol. 2016 Mar; 27(3):848-62. PMID: 26160898; PMCID: PMC4769195 [Available on 03/01/17].
      View in: PubMed, PubMed Central
    22. Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015 Jun; 21(6):601-9. PMID: 25962121; PMCID: PMC4458177.
      View in: PubMed, PubMed Central
    23. Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J Am Soc Nephrol. 2015 Nov; 26(11):2741-52. PMID: 25858967; PMCID: PMC4625676 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    24. Anwar S, Larson DS, Naimi N, Ashraf M, Culiberk N, Liapis H, Wei C, Reiser J, Brennan DC. A case report of adrenocorticotropic hormone to treat recurrent focal segmental glomerular sclerosis post-transplantation and biomarker monitoring. Front Med (Lausanne). 2015; 2:13. PMID: 25853133; PMCID: PMC4367432.
      View in: PubMed, PubMed Central
    25. Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015 Mar 10; 6:6496. PMID: 25754093; PMCID: PMC4366504.
      View in: PubMed, PubMed Central
    26. Whittier WL, Reiser J. Lupus nephritis: through the looking-glass. Lupus. 2015 May; 24(6):533-5. PMID: 25721124.
      View in: PubMed
    27. Lam PY, Mangos S, Green JM, Reiser J, Huttenlocher A. In vivo imaging and characterization of actin microridges. PLoS One. 2015; 10(1):e0115639. PMID: 25629723; PMCID: PMC4309568.
      View in: PubMed, PubMed Central
    28. Ravani P, Rossi R, Bonanni A, Quinn RR, Sica F, Bodria M, Pasini A, Montini G, Edefonti A, Belingheri M, De Giovanni D, Barbano G, Degl'Innocenti L, Scolari F, Murer L, Reiser J, Fornoni A, Ghiggeri GM. Rituximab in Children with Steroid-Dependent Nephrotic Syndrome: A Multicenter, Open-Label, Noninferiority, Randomized Controlled Trial. J Am Soc Nephrol. 2015 Sep; 26(9):2259-66. PMID: 25592855; PMCID: PMC4552120.
      View in: PubMed, PubMed Central
    29. Meijers BK, Reiser J. Reassessing the Reassessment of suPAR in Glomerular Disease. Front Med (Lausanne). 2014; 1:59. PMID: 25593929; PMCID: PMC4294199.
      View in: PubMed, PubMed Central
    30. Kobayashi N, Ueno T, Ohashi K, Yamashita H, Takahashi Y, Sakamoto K, Manabe S, Hara S, Takashima Y, Dan T, Pastan I, Miyata T, Kurihara H, Matsusaka T, Reiser J, Nagata M. Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated ß1-integrin endocytosis. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F614-26. PMID: 25587125; PMCID: PMC4360033.
      View in: PubMed, PubMed Central
    31. Kopp JB, Winkler CA, Zhao X, Radeva MK, Gassman JJ, D'Agati VD, Nast CC, Wei C, Reiser J, Guay-Woodford LM, Pollak MR, Hildebrandt F, Moxey-Mims M, Gipson DS, Trachtman H, Friedman AL, Kaskel FJ. Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial. J Am Soc Nephrol. 2015 Jun; 26(6):1443-8. PMID: 25573908; PMCID: PMC4446865.
      View in: PubMed, PubMed Central
    32. Li M, Armelloni S, Zennaro C, Wei C, Corbelli A, Ikehata M, Berra S, Giardino L, Mattinzoli D, Watanabe S, Agostoni C, Edefonti A, Reiser J, Messa P, Rastaldi MP. BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44. PMID: 25408545; PMCID: PMC4356648.
      View in: PubMed, PubMed Central
    33. Gupta V, Reiser J. MicroRNAs: a macroview into focal segmental glomerulosclerosis. Am J Kidney Dis. 2015 Feb; 65(2):206-8. PMID: 25616630.
      View in: PubMed
    34. Delville M, Sigdel TK, Wei C, Li J, Hsieh SC, Fornoni A, Burke GW, Bruneval P, Naesens M, Jackson A, Alachkar N, Canaud G, Legendre C, Anglicheau D, Reiser J, Sarwal MM. A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation. Sci Transl Med. 2014 Oct 01; 6(256):256ra136. PMID: 25273097; PMCID: PMC4394366.
      View in: PubMed, PubMed Central
    35. Garin EH, Reiser J, Cara-Fuentes G, Wei C, Matar D, Wang H, Alachkar N, Johnson RJ. Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis. Pediatr Nephrol. 2015 Mar; 30(3):469-77. PMID: 25239302; PMCID: PMC4869736.
      View in: PubMed, PubMed Central
    36. Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Front Med (Lausanne). 2014; 1:28. PMID: 25593903; PMCID: PMC4291843.
      View in: PubMed, PubMed Central
    37. Reiser J, Nast CC, Alachkar N. Permeability factors in focal and segmental glomerulosclerosis. Adv Chronic Kidney Dis. 2014 Sep; 21(5):417-21. PMID: 25168830; PMCID: PMC4149759.
      View in: PubMed, PubMed Central
    38. Peev V, Reiser J, Alachkar N. Diabetes mellitus in the transplanted kidney. Front Endocrinol (Lausanne). 2014; 5:141. PMID: 25221544; PMCID: PMC4145713.
      View in: PubMed, PubMed Central
    39. Trachtman H, Reiser J. suPAR is the circulating factor in some but not all FSGS. Nat Rev Nephrol. 2014 Oct; 10(10):610. PMID: 25157837.
      View in: PubMed
    40. Yoo TH, Pedigo CE, Guzman J, Correa-Medina M, Wei C, Villarreal R, Mitrofanova A, Leclercq F, Faul C, Li J, Kretzler M, Nelson RG, Lehto M, Forsblom C, Groop PH, Reiser J, Burke GW, Fornoni A, Merscher S. Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease. J Am Soc Nephrol. 2015 Jan; 26(1):133-47. PMID: 24925721; PMCID: PMC4279736.
      View in: PubMed, PubMed Central
    41. Cara-Fuentes G, Johnson RJ, Reiser J, Garin EH. CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance: response. Pediatr Nephrol. 2014 Aug; 29(8):1467-8. PMID: 24817342; PMCID: PMC4136515.
      View in: PubMed, PubMed Central
    42. Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J. Reduction of proteinuria through podocyte alkalinization. J Biol Chem. 2014 Jun 20; 289(25):17454-67. PMID: 24817115; PMCID: PMC4067184.
      View in: PubMed, PubMed Central
    43. Reiser J, Chapman H. Soluble urokinase-type plasminogen activator receptor in FSGS: stirred but not shaken. J Am Soc Nephrol. 2014 Aug; 25(8):1611-3. PMID: 24790180; PMCID: PMC4116074.
      View in: PubMed, PubMed Central
    44. Fiorina P, Vergani A, Bassi R, Niewczas MA, Altintas MM, Pezzolesi MG, D'Addio F, Chin M, Tezza S, Ben Nasr M, Mattinzoli D, Ikehata M, Corradi D, Schumacher V, Buvall L, Yu CC, Chang JM, La Rosa S, Finzi G, Solini A, Vincenti F, Rastaldi MP, Reiser J, Krolewski AS, Mundel PH, Sayegh MH. Role of podocyte B7-1 in diabetic nephropathy. J Am Soc Nephrol. 2014 Jul; 25(7):1415-29. PMID: 24676639; PMCID: PMC4073425.
      View in: PubMed, PubMed Central
    45. Alachkar N, Carter-Monroe N, Reiser J. Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2014 Mar 27; 370(13):1263-4. PMID: 24670180.
      View in: PubMed
    46. Lin CL, Lee PH, Hsu YC, Lei CC, Ko JY, Chuang PC, Huang YT, Wang SY, Wu SL, Chen YS, Chiang WC, Reiser J, Wang FS. MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction. J Am Soc Nephrol. 2014 Aug; 25(8):1698-709. PMID: 24578127; PMCID: PMC4116051.
      View in: PubMed, PubMed Central
    47. Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S. Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. J Clin Invest. 2014 Mar; 124(3):1098-113. PMID: 24531545; PMCID: PMC3934159.
      View in: PubMed, PubMed Central
    48. Adair BD, Altintas MM, Möller CC, Arnaout MA, Reiser J. Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy. J Am Soc Nephrol. 2014 Jul; 25(7):1465-73. PMID: 24511139; PMCID: PMC4073441.
      View in: PubMed, PubMed Central
    49. Kistler AD, Caicedo A, Abdulreda MH, Faul C, Kerjaschki D, Berggren PO, Reiser J, Fornoni A. In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye. Sci Rep. 2014 Jan 27; 4:3872. PMID: 24464028; PMCID: PMC3902446.
      View in: PubMed, PubMed Central
    50. Reiser J, Fornoni A. Rituximab: a boot to protect the foot. J Am Soc Nephrol. 2014 Apr; 25(4):647-8. PMID: 24459230; PMCID: PMC3968512.
      View in: PubMed, PubMed Central
    51. Reiser J, Sever S, Faul C. Signal transduction in podocytes--spotlight on receptor tyrosine kinases. Nat Rev Nephrol. 2014 Feb; 10(2):104-15. PMID: 24394191; PMCID: PMC4109315.
      View in: PubMed, PubMed Central
    52. Reiser J, Alachkar N. Proteinuria: abate or applaud abatacept in proteinuric kidney disease? Nat Rev Nephrol. 2014 03; 10(3):128-30. PMID: 24375054.
      View in: PubMed
    53. Cara-Fuentes G, Wei C, Segarra A, Ishimoto T, Rivard C, Johnson RJ, Reiser J, Garin EH. CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol. 2014 Aug; 29(8):1363-71. PMID: 24263531; PMCID: PMC4136522.
      View in: PubMed, PubMed Central
    54. Müller-Krebs S, Weber L, Tsobaneli J, Kihm LP, Reiser J, Zeier M, Schwenger V. Cellular effects of everolimus and sirolimus on podocytes. PLoS One. 2013; 8(11):e80340. PMID: 24260371; PMCID: PMC3829970.
      View in: PubMed, PubMed Central
    55. Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. J Biol Chem. 2013 Dec 20; 288(51):36598-609. PMID: 24194522; PMCID: PMC3868772.
      View in: PubMed, PubMed Central
    56. Alachkar N, Wei C, Arend LJ, Jackson AM, Racusen LC, Fornoni A, Burke G, Rabb H, Kakkad K, Reiser J, Estrella MM. Podocyte effacement closely links to suPAR levels at time of posttransplantation focal segmental glomerulosclerosis occurrence and improves with therapy. Transplantation. 2013 Oct 15; 96(7):649-56. PMID: 23842190; PMCID: PMC4026282.
      View in: PubMed, PubMed Central
    57. Reiser J. Akt2 relaxes podocytes in chronic kidney disease. Nat Med. 2013 Oct; 19(10):1212-3. PMID: 24100980.
      View in: PubMed
    58. Rangel EB, Gomes SA, Dulce RA, Premer C, Rodrigues CO, Kanashiro-Takeuchi RM, Oskouei B, Carvalho DA, Ruiz P, Reiser J, Hare JM. C-kit(+) cells isolated from developing kidneys are a novel population of stem cells with regenerative potential. Stem Cells. 2013 Aug; 31(8):1644-56. PMID: 23733311; PMCID: PMC3804254.
      View in: PubMed, PubMed Central
    59. Sever S, Trachtman H, Wei C, Reiser J. Is there clinical value in measuring suPAR levels in FSGS? Clin J Am Soc Nephrol. 2013 Aug; 8(8):1273-5. PMID: 23886567; PMCID: PMC3731899.
      View in: PubMed, PubMed Central
    60. Ravani P, Ponticelli A, Siciliano C, Fornoni A, Magnasco A, Sica F, Bodria M, Caridi G, Wei C, Belingheri M, Ghio L, Merscher-Gomez S, Edefonti A, Pasini A, Montini G, Murtas C, Wang X, Muruve D, Vaglio A, Martorana D, Pani A, Scolari F, Reiser J, Ghiggeri GM. Rituximab is a safe and effective long-term treatment for children with steroid and calcineurin inhibitor-dependent idiopathic nephrotic syndrome. Kidney Int. 2013 Nov; 84(5):1025-33. PMID: 23739238; PMCID: PMC3816123.
      View in: PubMed, PubMed Central
    61. Trachtman H, Wei C, Reiser J. Circulating factor in FSGS: a black sheep in the suPAR family? Pediatr Nephrol. 2013 Jul; 28(7):1151-2. PMID: 23572245; PMCID: PMC4109301.
      View in: PubMed, PubMed Central
    62. Morath C, Wei C, Macher-Goeppinger S, Schwenger V, Zeier M, Reiser J. Management of severe recurrent focal segmental glomerulosclerosis through circulating soluble urokinase receptor modification. Am J Ther. 2013 Mar-Apr; 20(2):226-9. PMID: 23466622.
      View in: PubMed
    63. Cara-Fuentes G, Araya C, Wei C, Rivard C, Ishimoto T, Reiser J, Johnson RJ, Garin EH. CD80, suPAR and nephrotic syndrome in a case of NPHS2 mutation. Nefrologia. 2013; 33(5):727-31. PMID: 24089165.
      View in: PubMed
    64. Reiser J. Circulating permeability factor suPAR: from concept to discovery to clinic. Trans Am Clin Climatol Assoc. 2013; 124:133-8. PMID: 23874017; PMCID: PMC3715931.
      View in: PubMed, PubMed Central
    65. Reiser J, Sever S. Podocyte biology and pathogenesis of kidney disease. Annu Rev Med. 2013; 64:357-66. PMID: 23190150; PMCID: PMC3736800.
      View in: PubMed, PubMed Central
    66. Kemper MJ, Wei C, Reiser J. Transmission of glomerular permeability factor soluble urokinase plasminogen activator receptor (suPAR) from a mother to child. Am J Kidney Dis. 2013 Feb; 61(2):352. PMID: 23182533.
      View in: PubMed
    67. Wei C, Trachtman H, Li J, Dong C, Friedman AL, Gassman JJ, McMahan JL, Radeva M, Heil KM, Trautmann A, Anarat A, Emre S, Ghiggeri GM, Ozaltin F, Haffner D, Gipson DS, Kaskel F, Fischer DC, Schaefer F, Reiser J. Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol. 2012 Dec; 23(12):2051-9. PMID: 23138488; PMCID: PMC3507361.
      View in: PubMed, PubMed Central
    68. Schell CB, Kerjaschki D, Reiser J, Huber TB. Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference. Kidney Int. 2012 Nov; 82(10):1041-3. PMID: 23128112.
      View in: PubMed
    69. Zhang B, Shi W, Ma J, Sloan A, Faul C, Wei C, Reiser J, Yang Y, Liu S, Wang W. The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury. J Mol Med (Berl). 2012 Dec; 90(12):1407-20. PMID: 23015147; PMCID: PMC4109322.
      View in: PubMed, PubMed Central
    70. Mangos S, Amaral AP, Faul C, Jüppner H, Reiser J, Wolf M. Expression of fgf23 and aklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio. Nephrol Dial Transplant. 2012 Dec; 27(12):4314-22. PMID: 22885518; PMCID: PMC3520084.
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    71. Trachtman H, Gipson DS, Kaskel F, Ghiggeri GM, Faul C, Gupta V, Fornoni A, Burke GW, Thomas DB, Barisoni L, Schaefer F, Wei C, Reiser J. Regarding Maas's editorial letter on serum suPAR levels. Kidney Int. 2012 Aug; 82(4):492. PMID: 22846820; PMCID: PMC4480609.
      View in: PubMed, PubMed Central
    72. Reiser J, Wei C, Tumlin J. Soluble urokinase receptor and focal segmental glomerulosclerosis. Curr Opin Nephrol Hypertens. 2012 Jul; 21(4):428-32. PMID: 22569341.
      View in: PubMed
    73. Chang JW, Pardo V, Sageshima J, Chen L, Tsai HL, Reiser J, Wei C, Ciancio G, Burke GW, Fornoni A. Podocyte foot process effacement in postreperfusion allograft biopsies correlates with early recurrence of proteinuria in focal segmental glomerulosclerosis. Transplantation. 2012 Jun 27; 93(12):1238-44. PMID: 22499148; PMCID: PMC3432300.
      View in: PubMed, PubMed Central
    74. Kistler AD, Altintas MM, Reiser J. Podocyte GTPases regulate kidney filter dynamics. Kidney Int. 2012 Jun; 81(11):1053-5. PMID: 22584591; PMCID: PMC3354621.
      View in: PubMed, PubMed Central
    75. Müller-Krebs S, Kihm LP, Madhusudhan T, Isermann B, Reiser J, Zeier M, Schwenger V. Human RAGE antibody protects against AGE-mediated podocyte dysfunction. Nephrol Dial Transplant. 2012 Aug; 27(8):3129-36. PMID: 22510380.
      View in: PubMed
    76. Altintas MM, Nayer B, Walford EC, Johnson KB, Gaidosh G, Reiser J, De La Cruz-Munoz N, Ortega LM, Nayer A. Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice. Lipids Health Dis. 2012 Feb 07; 11:21. PMID: 22313574; PMCID: PMC3287967.
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    77. Kistler AD, Faul C, Reiser J. TRPC6 in podocytes: questions and commentary on the article by Jiang et al., 'Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca21 and RhoA activation'. Exp Biol Med (Maywood). 2011 Dec; 236(12):1361; author reply 1362-3. PMID: 22242226.
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    79. Altintas MM, Rossetti MA, Nayer B, Puig A, Zagallo P, Ortega LM, Johnson KB, McNamara G, Reiser J, Mendez AJ, Nayer A. Apoptosis, mastocytosis, and diminished adipocytokine gene expression accompany reduced epididymal fat mass in long-standing diet-induced obese mice. Lipids Health Dis. 2011 Nov 03; 10:198. PMID: 22051061; PMCID: PMC3229589.
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    80. Mangos S, Reiser J. Fishing for new glomerular disease-related genes. J Am Soc Nephrol. 2011 Nov; 22(11):1960-2. PMID: 21997399.
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    81. Daftarian P, Chowdhury R, Ames P, Wei C, King AD, de Rivero Vaccari JP, Dillon L, Price J, Leung H, Ashlock B, Mesri E, Perez V, Züchner S, Reiser J, Lemmon V, Keane RW. In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations. Hybridoma (Larchmt). 2011 Oct; 30(5):409-18. PMID: 22008067; PMCID: PMC3241927.
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    82. Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Invest. 2011 Oct; 121(10):3965-80. PMID: 21911934; PMCID: PMC3195478.
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    83. Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal. 2011 Sep 06; 4(189):ra57. PMID: 21900205; PMCID: PMC4507414.
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    84. Nijenhuis T, Sloan AJ, Hoenderop JG, Flesche J, van Goor H, Kistler AD, Bakker M, Bindels RJ, de Boer RA, Möller CC, Hamming I, Navis G, Wetzels JF, Berden JH, Reiser J, Faul C, van der Vlag J. Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway. Am J Pathol. 2011 Oct; 179(4):1719-32. PMID: 21839714; PMCID: PMC3181349.
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    85. Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med. 2011 Jul 31; 17(8):952-60. PMID: 21804539; PMCID: PMC4089394.
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    86. Krautkrämer E, Grouls S, Stein N, Reiser J, Zeier M. Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts. J Virol. 2011 Oct; 85(19):9811-23. PMID: 21775443; PMCID: PMC3196447.
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    87. Fornoni A, Sageshima J, Wei C, Merscher-Gomez S, Aguillon-Prada R, Jauregui AN, Li J, Mattiazzi A, Ciancio G, Chen L, Zilleruelo G, Abitbol C, Chandar J, Seeherunvong W, Ricordi C, Ikehata M, Rastaldi MP, Reiser J, Burke GW. Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med. 2011 Jun 01; 3(85):85ra46. PMID: 21632984; PMCID: PMC3719858.
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    88. Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest. 2011 May; 121(5):2013-24. PMID: 21540551; PMCID: PMC3083770.
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    89. Wei C, Reiser J. Minimal change disease as a modifiable podocyte paracrine disorder. Nephrol Dial Transplant. 2011 Jun; 26(6):1776-7. PMID: 21414975; PMCID: PMC3145403.
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    90. Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE. Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy. Am J Hum Genet. 2011 Mar 11; 88(3):273-82. PMID: 21353195; PMCID: PMC3059419.
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    91. Reiser J. Filtering new facts about kidney disease. Nat Med. 2011 Jan; 17(1):44-5. PMID: 21217681.
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    92. El Hindi S, Reiser J. TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease. Pediatr Nephrol. 2011 Jul; 26(7):1057-64. PMID: 21161284; PMCID: PMC3098353.
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    93. Altintas MM, Azad A, Nayer B, Contreras G, Zaias J, Faul C, Reiser J, Nayer A. Mast cells, macrophages, and crown-like structures distinguish subcutaneous from visceral fat in mice. J Lipid Res. 2011 Mar; 52(3):480-8. PMID: 21148461; PMCID: PMC3035684.
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    94. Papeta N, Zheng Z, Schon EA, Brosel S, Altintas MM, Nasr SH, Reiser J, D'Agati VD, Gharavi AG. Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice. J Clin Invest. 2010 Nov; 120(11):4055-64. PMID: 20978358; PMCID: PMC2964992.
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    95. Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Direct dynamin-actin interactions regulate the actin cytoskeleton. EMBO J. 2010 Nov 03; 29(21):3593-606. PMID: 20935625; PMCID: PMC2982766.
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    96. Reiser J, Adair B, Reinheckel T. Specialized roles for cysteine cathepsins in health and disease. J Clin Invest. 2010 Oct; 120(10):3421-31. PMID: 20921628; PMCID: PMC2947230.
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    97. Krall P, Canales CP, Kairath P, Carmona-Mora P, Molina J, Carpio JD, Ruiz P, Mezzano SA, Li J, Wei C, Reiser J, Young JI, Walz K. Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease. PLoS One. 2010 Sep 20; 5(9):e12859. PMID: 20877463; PMCID: PMC2942896.
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    98. Dryer SE, Reiser J. TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology. Am J Physiol Renal Physiol. 2010 Oct; 299(4):F689-701. PMID: 20685822; PMCID: PMC2957253.
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    99. Kistler AD, Reiser J. Maximal 'CD80-uria' with minimal change. Kidney Int. 2010 Aug; 78(3):236-8. PMID: 20631735.
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    100. Chiang WC, Geel TM, Altintas MM, Sever S, Ruiters MH, Reiser J. Establishment of protein delivery systems targeting podocytes. PLoS One. 2010 Jul 29; 5(7):e11837. PMID: 20686602; PMCID: PMC2912276.
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    101. Hauser PV, Pippin JW, Kaiser C, Krofft RD, Brinkkoetter PT, Hudkins KL, Kerjaschki D, Reiser J, Alpers CE, Shankland SJ. Novel siRNA delivery system to target podocytes in vivo. PLoS One. 2010 Mar 01; 5(3):e9463. PMID: 20209128; PMCID: PMC2830889.
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    102. Kistler AD, Peev V, Forst AL, El Hindi S, Altintas MM, Reiser J. Enzymatic disease of the podocyte. Pediatr Nephrol. 2010 Jun; 25(6):1017-23. PMID: 20130922; PMCID: PMC4109305.
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    103. Reiser J, Gupta V, Kistler AD. Toward the development of podocyte-specific drugs. Kidney Int. 2010 Apr; 77(8):662-8. PMID: 20130528; PMCID: PMC4089392.
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    104. Mundel P, Reiser J. Proteinuria: an enzymatic disease of the podocyte? Kidney Int. 2010 Apr; 77(7):571-80. PMID: 19924101; PMCID: PMC4109304.
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    105. Heeringa SF, Möller CC, Du J, Yue L, Hinkes B, Chernin G, Vlangos CN, Hoyer PF, Reiser J, Hildebrandt F. A novel TRPC6 mutation that causes childhood FSGS. PLoS One. 2009 Nov 10; 4(11):e7771. PMID: 19936226; PMCID: PMC2777406.
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    106. Fornoni A, Jeon J, Varona Santos J, Cobianchi L, Jauregui A, Inverardi L, Mandic SA, Bark C, Johnson K, McNamara G, Pileggi A, Molano RD, Reiser J, Tryggvason K, Kerjaschki D, Berggren PO, Mundel P, Ricordi C. Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release. Diabetes. 2010 Jan; 59(1):190-9. PMID: 19833886; PMCID: PMC2797921.
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    107. Möller CC, Flesche J, Reiser J. Sensitizing the Slit Diaphragm with TRPC6 ion channels. J Am Soc Nephrol. 2009 May; 20(5):950-3. PMID: 18784209.
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    108. Faul C, Donnelly M, Merscher-Gomez S, Chang YH, Franz S, Delfgaauw J, Chang JM, Choi HY, Campbell KN, Kim K, Reiser J, Mundel P. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med. 2008 Sep; 14(9):931-8. PMID: 18724379; PMCID: PMC4109287.
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    109. Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22; 283(34):23033-8. PMID: 18562307; PMCID: PMC2516981.
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    110. Möller CC, Mangos S, Drummond IA, Reiser J. Expression of trpC1 and trpC6 orthologs in zebrafish. Gene Expr Patterns. 2008 May; 8(5):291-6. PMID: 18378501; PMCID: PMC2431112.
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    111. Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Modification of kidney barrier function by the urokinase receptor. Nat Med. 2008 Jan; 14(1):55-63. PMID: 18084301.
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    112. Reiser J, Mundel P. Dual effects of RAS blockade on blood pressure and podocyte function. Curr Hypertens Rep. 2007 Nov; 9(5):403-8. PMID: 18177588.
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    113. Sever S, Altintas MM, Nankoe SR, Möller CC, Ko D, Wei C, Henderson J, del Re EC, Hsing L, Erickson A, Cohen CD, Kretzler M, Kerjaschki D, Rudensky A, Nikolic B, Reiser J. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. J Clin Invest. 2007 Aug; 117(8):2095-104. PMID: 17671649; PMCID: PMC1934589.
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    114. Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J. Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol. 2007 Jan; 18(1):29-36. PMID: 17167110.
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    115. Yao J, Gutierrez OM, Reiser J. Emphysematous pyelonephritis. Kidney Int. 2007 Mar; 71(5):462-5. PMID: 17136032.
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    116. Möller CC, Pollak MR, Reiser J. The genetic basis of human glomerular disease. Adv Chronic Kidney Dis. 2006 Apr; 13(2):166-73. PMID: 16580618.
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    117. Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005 Jul; 37(7):739-44. PMID: 15924139; PMCID: PMC1360984.
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    118. Asanuma K, Kim K, Oh J, Giardino L, Chabanis S, Faul C, Reiser J, Mundel P. Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J Clin Invest. 2005 May; 115(5):1188-98. PMID: 15841212; PMCID: PMC1070637.
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    119. Reiser J, Mundel P. Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome. J Am Soc Nephrol. 2004 Sep; 15(9):2246-8. PMID: 15339973.
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    120. Reiser J, Oh J, Shirato I, Asanuma K, Hug A, Mundel TM, Honey K, Ishidoh K, Kominami E, Kreidberg JA, Tomino Y, Mundel P. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem. 2004 Aug 13; 279(33):34827-32. PMID: 15197181.
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    121. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, Rastaldi MP, Calvaresi N, Watanabe H, Schwarz K, Faul C, Kretzler M, Davidson A, Sugimoto H, Kalluri R, Sharpe AH, Kreidberg JA, Mundel P. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004 May; 113(10):1390-7. PMID: 15146236; PMCID: PMC406528.
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    122. Oh J, Reiser J, Mundel P. Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome. Pediatr Nephrol. 2004 Feb; 19(2):130-7. PMID: 14673634.
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    123. Reiser J, von Gersdorff G, Simons M, Schwarz K, Faul C, Giardino L, Heider T, Loos M, Mundel P. Novel concepts in understanding and management of glomerular proteinuria. Nephrol Dial Transplant. 2002 Jun; 17(6):951-5. PMID: 12032178.
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    124. Saleem MA, O'Hare MJ, Reiser J, Coward RJ, Inward CD, Farren T, Xing CY, Ni L, Mathieson PW, Mundel P. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol. 2002 Mar; 13(3):630-8. PMID: 11856766.
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    125. Wolf P, Reiser JR, Fellow JE, Haghighi P. Pancreatitis in patients with AIDS presumptively due to CMV. J Clin Lab Anal. 1989; 3(3):152-5. PMID: 2474062.
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