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Jochen Reiser

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Nephrology
Address1750 W. Harrison St
Chicago IL 60612
Phone312-942-6639
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    Collapse Overview 
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    My Scopus ID is 7004772937.
    My NIH COMMONS name is JREISER.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Nusshag C, Rupp C, Schmitt F, Krautkrämer E, Speer C, Kälble F, Tamulyte S, Bruckner T, Zeier M, Reiser J, Weigand MA, Uhle F, Merle U, Morath C, Brenner T. Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study. Crit Care Med. 2019 Oct 04. PMID: 31584458.
      View in: PubMed
    2. Polat OK, Uno M, Maruyama T, Tran HN, Imamura K, Wong CF, Sakaguchi R, Ariyoshi M, Itsuki K, Ichikawa J, Morii T, Shirakawa M, Inoue R, Asanuma K, Reiser J, Tochio H, Mori Y, Mori MX. Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 Sep; 30(9):1587-1603. PMID: 31266820.
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    3. Hayek SS, Landsittel DP, Wei C, Zeier M, Yu ASL, Torres VE, Roth S, Pao CS, Reiser J. Soluble Urokinase Plasminogen Activator Receptor and Decline in Kidney Function in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2019 Jul; 30(7):1305-1313. PMID: 31171572.
      View in: PubMed
    4. Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. J Clin Invest. 2019 04 02; 129(5):1946-1959. PMID: 30730305.
      View in: PubMed
    5. Koh KH, Cao Y, Mangos S, Tardi NJ, Dande RR, Lee HW, Samelko B, Altintas MM, Schmitz VP, Lee H, Mukherjee K, Peev V, Cimbaluk DJ, Reiser J, Hahm E. Nonimmune cell-derived ICOS ligand functions as a renoprotective avß3 integrin-selective antagonist. J Clin Invest. 2019 Apr 01; 129(4):1713-1726. PMID: 30747722.
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    6. Altintas MM, Reiser J. More expression, less function: cleaved dynamin in glomerular kidney disease. J Pathol. 2019 Apr; 247(4):413-415. PMID: 30549263.
      View in: PubMed
    7. Sommerer C, Zeier M, Morath C, Reiser J, Scharnagl H, Stojakovic T, Delgado GE, März W, Kleber ME. Soluble urokinase plasminogen activation receptor and long-term outcomes in persons undergoing coronary angiography. Sci Rep. 2019 Jan 24; 9(1):475. PMID: 30679668.
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    8. Chan CY, Resontoc LP, Qader MA, Chan YH, Liu ID, Lau PY, Than M, Yeo WS, Loh AH, Tan PH, Wei C, Reiser J, Biswas SK, Ng KH, Yap HK. MeSsAGe risk score: tool for renal biopsy decision in steroid-dependent nephrotic syndrome. Pediatr Res. 2019 Mar; 85(4):477-483. PMID: 30659270.
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    9. Alhamad T, Manllo Dieck J, Younus U, Matar D, Alasfar S, Vujjini V, Wall D, Kanawati B, Reiser J, Brennan DC, Alachkar N. ACTH Gel in Resistant Focal Segmental Glomerulosclerosis After Kidney Transplantation. Transplantation. 2019 01; 103(1):202-209. PMID: 29894413.
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    10. Alachkar N, Li J, Matar D, Vujjini V, Alasfar S, Tracy M, Reiser J, Wei C. Monitoring suPAR levels in post-kidney transplant focal segmental glomerulosclerosis treated with therapeutic plasma exchange and rituximab. BMC Nephrol. 2018 12 17; 19(1):361. PMID: 30558559.
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    11. Hägele S, Müller A, Nusshag C, Reiser J, Zeier M, Krautkrämer E. Motility of human renal cells is disturbed by infection with pathogenic hantaviruses. BMC Infect Dis. 2018 Dec 12; 18(1):645. PMID: 30541481.
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    12. Altintas MM, Reiser J. Podocytes: Way to Go. Am J Pathol. 2019 02; 189(2):226-228. PMID: 30543788.
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    13. Hägele S, Müller A, Nusshag C, Reiser J, Zeier M, Krautkrämer E. Virus- and cell type-specific effects in orthohantavirus infection. Virus Res. 2019 01 15; 260:102-113. PMID: 30508604.
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    14. Hoenigl M, Moser C, Funderburg N, Bosch R, Kantor A, Zhang Y, Eugen-Olsen J, Finkelman M, Reiser J, Landay A, Moisi D, Lederman MM, Gianella S. Soluble Urokinase Plasminogen Activator Receptor (suPAR) is predictive of Non-AIDS Events during Antiretroviral Therapy-mediated Viral Suppression. Clin Infect Dis. 2018 Nov 12. PMID: 30418519.
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    15. Shuster S, Ankawi G, Licht C, Reiser J, Wang X, Wei C, Chitayat D, Hladunewich M. Fetal Renal Echogenicity Associated with Maternal Focal Segmental Glomerulosclerosis: The Effect of Transplacental Transmission of Permeability Factor suPAR. J Clin Med. 2018 Oct 04; 7(10). PMID: 30287750.
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    16. Rangel EB, Gomes SA, Kanashiro-Takeuchi R, Saltzman RG, Wei C, Ruiz P, Reiser J, Hare JM. Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria. Sci Rep. 2018 10 03; 8(1):14723. PMID: 30283057.
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    17. Lv L, Wang F, Wu L, Wang JW, Cui Z, Hayek SS, Wei C, Reiser J, He K, Zhang L, Chen M, Zhao MH. Soluble urokinase-type plasminogen activator receptor and incident end-stage renal disease in Chinese patients with chronic kidney disease. Nephrol Dial Transplant. 2018 Aug 13. PMID: 30124995.
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    18. Chen D, Xie R, Shu B, Landay AL, Wei C, Reiser J, Spagnoli A, Torquati A, Forsyth CB, Keshavarzian A, Sumner DR. Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging. Ann N Y Acad Sci. 2019 Apr; 1442(1):48-60. PMID: 30101565.
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    19. Wang X, Reiser J. Stop TRPC5 in Kidney Disease: A Game Changer for Renal Allograft Protection? Transplantation. 2018 07; 102(7):1027-1029. PMID: 29952922.
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    20. Luo S, Coresh J, Tin A, Rebholz CM, Chen TK, Hayek SS, Tracy M, Lipkowitz MS, Appel LJ, Levey AS, Inker LA, Reiser J, Grams ME. Soluble Urokinase-Type Plasminogen Activator Receptor in Black Americans with CKD. Clin J Am Soc Nephrol. 2018 07 06; 13(7):1013-1021. PMID: 29903900.
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    21. Torino C, Pizzini P, Cutrupi S, Postorino M, Tripepi G, Mallamaci F, Reiser J, Zoccali C. Soluble Urokinase Plasminogen Activator Receptor (suPAR) and All-Cause and Cardiovascular Mortality in Diverse Hemodialysis Patients. Kidney Int Rep. 2018 Sep; 3(5):1100-1109. PMID: 30197976.
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    22. Hayek SS, Divers J, Raad M, Xu J, Bowden DW, Tracy M, Reiser J, Freedman BI. Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High-Sensitivity C-Reactive Protein. J Am Heart Assoc. 2018 05 01; 7(9). PMID: 29716888.
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    23. Höhne M, Frese CK, Grahammer F, Dafinger C, Ciarimboli G, Butt L, Binz J, Hackl MJ, Rahmatollahi M, Kann M, Schneider S, Altintas MM, Schermer B, Reinheckel T, Göbel H, Reiser J, Huber TB, Kramann R, Seeger-Nukpezah T, Liebau MC, Beck BB, Benzing T, Beyer A, Rinschen MM. Single-nephron proteomes connect morphology and function in proteinuric kidney disease. Kidney Int. 2018 06; 93(6):1308-1319. PMID: 29530281.
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    24. Alasfar S, Matar D, Montgomery RA, Desai N, Lonze B, Vujjini V, Estrella MM, Manllo Dieck J, Khneizer G, Sever S, Reiser J, Alachkar N. Rituximab and Therapeutic Plasma Exchange in Recurrent Focal Segmental Glomerulosclerosis Postkidney Transplantation. Transplantation. 2018 03; 102(3):e115-e120. PMID: 29189487.
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    25. Ren G, Tardi NJ, Matsuda F, Koh KH, Ruiz P, Wei C, Altintas MM, Ploegh H, Reiser J. Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease. Am J Physiol Renal Physiol. 2018 03 01; 314(3):F471-F482. PMID: 29167172.
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    26. Liu WJ, Reiser J, Park TS, Liu Z, Ishibe S. New Insights into Diabetic Kidney Disease: The Potential Pathogenesis and Therapeutic Targets. J Diabetes Res. 2017; 2017:3945469. PMID: 29250556.
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    27. Schaefer F, Trachtman H, Wühl E, Kirchner M, Hayek SS, Anarat A, Duzova A, Mir S, Paripovic D, Yilmaz A, Lugani F, Arbeiter K, Litwin M, Oh J, Matteucci MC, Gellermann J, Wygoda S, Jankauskiene A, Klaus G, Dusek J, Testa S, Zurowska A, Caldas Afonso A, Tracy M, Wei C, Sever S, Smoyer W, Reiser J. Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children. JAMA Pediatr. 2017 11 06; 171(11):e172914. PMID: 28873129.
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    28. Wang X, Dande RR, Yu H, Samelko B, Miller RE, Altintas MM, Reiser J. TRPC5 Does Not Cause or Aggravate Glomerular Disease. J Am Soc Nephrol. 2018 02; 29(2):409-415. PMID: 29061651.
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    29. Lee HW, Arif E, Altintas MM, Quick K, Maheshwari S, Plezia A, Mahmood A, Reiser J, Nihalani D, Gupta V. High-content screening assay-based discovery of paullones as novel podocyte-protective agents. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F280-F292. PMID: 29046299.
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    30. Zeier M, Reiser J. suPAR and chronic kidney disease-a podocyte story. Pflugers Arch. 2017 Aug; 469(7-8):1017-1020. PMID: 28689240.
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    31. Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al-Dabet MM, Manoharan J, Nazir S, Elwakiel A, Bock F, Kohli S, Marquardt A, Sögüt I, Shahzad K, Müller AJ, Esmon CT, Nawroth PP, Reiser J, Chavakis T, Ruf W, Isermann B. Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. Blood. 2017 09 21; 130(12):1445-1455. PMID: 28687614.
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    32. Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. A tripartite complex of suPAR, APOL1 risk variants and avß3 integrin on podocytes mediates chronic kidney disease. Nat Med. 2017 Aug; 23(8):945-953. PMID: 28650456.
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    33. Gupta KH, Goldufsky JW, Wood SJ, Tardi NJ, Moorthy GS, Gilbert DZ, Zayas JP, Hahm E, Altintas MM, Reiser J, Shafikhani SH. Apoptosis and Compensatory Proliferation Signaling Are Coupled by CrkI-Containing Microvesicles. Dev Cell. 2017 06 19; 41(6):674-684.e5. PMID: 28633020.
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    34. Samman Tahhan A, Hayek SS, Sandesara P, Hajjari J, Hammadah M, O'Neal WT, Kelli HM, Alkhoder A, Ghasemzadeh N, Ko YA, Aida H, Gafeer MM, Abdelhadi N, Mohammed KH, Patel K, Arya S, Reiser J, Vaccarino V, Sperling L, Quyyumi A. Circulating soluble urokinase plasminogen activator receptor levels and peripheral arterial disease outcomes. Atherosclerosis. 2017 Sep; 264:108-114. PMID: 28728756.
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    35. Hahm E, Peev V, Reiser J. Extrarenal determinants of kidney filter function. Cell Tissue Res. 2017 07; 369(1):211-216. PMID: 28560690.
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    36. Dande RR, Peev V, Altintas MM, Reiser J. Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus. J Diabetes Res. 2017; 2017:3232848. PMID: 28596971.
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    37. Drechsler C, Hayek SS, Wei C, Sever S, Genser B, Krane V, Meinitzer A, März W, Wanner C, Reiser J. Soluble Urokinase Plasminogen Activator Receptor and Outcomes in Patients with Diabetes on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1265-1273. PMID: 28495863.
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    38. Reiser J, Lee HW, Gupta V, Altintas MM. A High-Content Screening Technology for Quantitatively Studying Podocyte Dynamics. Adv Chronic Kidney Dis. 2017 05; 24(3):183-188. PMID: 28501082.
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    39. Peev V, Hahm E, Reiser J. Unwinding focal segmental glomerulosclerosis. F1000Res. 2017; 6:466. PMID: 28491286.
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    40. Tardi NJ, Reiser J. The Use of Sildenafil for Glomerular Disease. J Am Soc Nephrol. 2017 05; 28(5):1329-1331. PMID: 28360220.
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    41. Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB. Targeting mTOR Signaling Can Prevent the Progression of FSGS. J Am Soc Nephrol. 2017 Jul; 28(7):2144-2157. PMID: 28270414.
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    42. Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest. 2017 Apr 03; 127(4):1271-1283. PMID: 28263189.
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    43. Hayek SS, Ko YA, Awad M, Ahmed H, Gray B, Hosny KM, Aida H, Tracy MJ, Wei C, Sever S, Reiser J, Quyyumi AA. Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study. Kidney Int Rep. 2017 May; 2(3):425-432. PMID: 29142970.
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    44. Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nat Med. 2017 01; 23(1):100-106. PMID: 27941791.
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    45. Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747. PMID: 27913625.
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    46. Müller-Deile J, Teng B, Schenk H, Haller H, Reiser J, Sever S, Schiffer M. Drugs targeting dynamin can restore cytoskeleton and focal contact alterations of urinary podocytes derived from patients with nephrotic syndrome. Ann Transl Med. 2016 Nov; 4(21):439. PMID: 27942530.
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    47. Gupta V, Reiser J. Stop that podocyte! Am J Physiol Renal Physiol. 2017 02 01; 312(2):F373-F374. PMID: 27760773.
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    48. Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S. Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. J Am Soc Nephrol. 2017 02; 28(2):446-451. PMID: 27432739.
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    49. Hamidi O, Reiser J, Hasler S. An Interferon-Induced Digital Vasculitis-Like Syndrome: A Case Report. Am J Ther. 2016 May-Jun; 23(3):e920-5. PMID: 24732907.
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    50. Yu H, Kistler A, Faridi MH, Meyer JO, Tryniszewska B, Mehta D, Yue L, Dryer S, Reiser J. Synaptopodin Limits TRPC6 Podocyte Surface Expression and Attenuates Proteinuria. J Am Soc Nephrol. 2016 Nov; 27(11):3308-3319. PMID: 27020855.
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    51. Hayek SS, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. N Engl J Med. 2016 03 03; 374(9):891. PMID: 26962914.
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    52. Reiser J, Altintas MM. Podocytes. F1000Res. 2016; 5. PMID: 26918173.
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    53. Staeck O, Slowinski T, Lieker I, Wu K, Rudolph B, Schmidt D, Brakemeier S, Neumayer HH, Wei C, Reiser J, Budde K, Halleck F, Khadzhynov D. Recurrent Primary Focal Segmental Glomerulosclerosis Managed With Intensified Plasma Exchange and Concomitant Monitoring of Soluble Urokinase-Type Plasminogen Activator Receptor-Mediated Podocyte ß3-integrin Activation. Transplantation. 2015 Dec; 99(12):2593-7. PMID: 26371597.
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    54. Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. N Engl J Med. 2015 Nov 12; 373(20):1916-25. PMID: 26539835.
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    55. Wei C, Sigdel TK, Sarwal MM, Reiser J. Circulating CD40 autoantibody and suPAR synergy drives glomerular injury. Ann Transl Med. 2015 Nov; 3(19):300. PMID: 26697460.
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    56. Sever S, Reiser J. CD2AP, dendrin, and cathepsin L in the kidney. Am J Pathol. 2015 Nov; 185(11):3129-30. PMID: 26506476.
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    57. Trachtman H, Vento S, Herreshoff E, Radeva M, Gassman J, Stein DT, Savin VJ, Sharma M, Reiser J, Wei C, Somers M, Srivastava T, Gipson DS. Efficacy of galactose and adalimumab in patients with resistant focal segmental glomerulosclerosis: report of the font clinical trial group. BMC Nephrol. 2015 Jul 22; 16:111. PMID: 26198842.
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    58. Altintas MM, Reiser J. Bridges to cross, burn, and mend: cells of renin lineage as podocyte progenitors. Am J Physiol Renal Physiol. 2015 Sep 15; 309(6):F499-500. PMID: 26180240.
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    59. Forst AL, Olteanu VS, Mollet G, Wlodkowski T, Schaefer F, Dietrich A, Reiser J, Gudermann T, Mederos y Schnitzler M, Storch U. Podocyte Purinergic P2X4 Channels Are Mechanotransducers That Mediate Cytoskeletal Disorganization. J Am Soc Nephrol. 2016 Mar; 27(3):848-62. PMID: 26160898.
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    60. Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015 Jun; 21(6):601-9. PMID: 25962121.
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    61. Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J Am Soc Nephrol. 2015 Nov; 26(11):2741-52. PMID: 25858967.
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    62. Anwar S, Larson DS, Naimi N, Ashraf M, Culiberk N, Liapis H, Wei C, Reiser J, Brennan DC. A case report of adrenocorticotropic hormone to treat recurrent focal segmental glomerular sclerosis post-transplantation and biomarker monitoring. Front Med (Lausanne). 2015; 2:13. PMID: 25853133.
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    63. Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015 Mar 10; 6:6496. PMID: 25754093.
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    64. Müller-Krebs S, Nissle K, Tsobaneli J, Zeier M, Kihm LP, Kender Z, Fleming T, Nawroth PP, Reiser J, Schwenger V. Effect of benfotiamine in podocyte damage induced by peritoneal dialysis fluid. Front Med (Lausanne). 2015; 2:10. PMID: 25806370.
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    65. Whittier WL, Reiser J. Lupus nephritis: through the looking-glass. Lupus. 2015 May; 24(6):533-5. PMID: 25721124.
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    66. Lam PY, Mangos S, Green JM, Reiser J, Huttenlocher A. In vivo imaging and characterization of actin microridges. PLoS One. 2015; 10(1):e0115639. PMID: 25629723.
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    67. Ravani P, Rossi R, Bonanni A, Quinn RR, Sica F, Bodria M, Pasini A, Montini G, Edefonti A, Belingheri M, De Giovanni D, Barbano G, Degl'Innocenti L, Scolari F, Murer L, Reiser J, Fornoni A, Ghiggeri GM. Rituximab in Children with Steroid-Dependent Nephrotic Syndrome: A Multicenter, Open-Label, Noninferiority, Randomized Controlled Trial. J Am Soc Nephrol. 2015 Sep; 26(9):2259-66. PMID: 25592855.
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    68. Meijers BK, Reiser J. Reassessing the Reassessment of suPAR in Glomerular Disease. Front Med (Lausanne). 2014; 1:59. PMID: 25593929.
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    69. Kobayashi N, Ueno T, Ohashi K, Yamashita H, Takahashi Y, Sakamoto K, Manabe S, Hara S, Takashima Y, Dan T, Pastan I, Miyata T, Kurihara H, Matsusaka T, Reiser J, Nagata M. Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated ß1-integrin endocytosis. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F614-26. PMID: 25587125.
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    70. Kopp JB, Winkler CA, Zhao X, Radeva MK, Gassman JJ, D'Agati VD, Nast CC, Wei C, Reiser J, Guay-Woodford LM, Pollak MR, Hildebrandt F, Moxey-Mims M, Gipson DS, Trachtman H, Friedman AL, Kaskel FJ. Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial. J Am Soc Nephrol. 2015 Jun; 26(6):1443-8. PMID: 25573908.
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    71. Li M, Armelloni S, Zennaro C, Wei C, Corbelli A, Ikehata M, Berra S, Giardino L, Mattinzoli D, Watanabe S, Agostoni C, Edefonti A, Reiser J, Messa P, Rastaldi MP. BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44. PMID: 25408545.
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    72. Gupta V, Reiser J. MicroRNAs: a macroview into focal segmental glomerulosclerosis. Am J Kidney Dis. 2015 Feb; 65(2):206-8. PMID: 25616630.
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    73. Delville M, Sigdel TK, Wei C, Li J, Hsieh SC, Fornoni A, Burke GW, Bruneval P, Naesens M, Jackson A, Alachkar N, Canaud G, Legendre C, Anglicheau D, Reiser J, Sarwal MM. A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation. Sci Transl Med. 2014 Oct 01; 6(256):256ra136. PMID: 25273097.
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    74. Garin EH, Reiser J, Cara-Fuentes G, Wei C, Matar D, Wang H, Alachkar N, Johnson RJ. Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis. Pediatr Nephrol. 2015 Mar; 30(3):469-77. PMID: 25239302.
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    75. Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Front Med (Lausanne). 2014; 1:28. PMID: 25593903.
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    76. Reiser J, Nast CC, Alachkar N. Permeability factors in focal and segmental glomerulosclerosis. Adv Chronic Kidney Dis. 2014 Sep; 21(5):417-21. PMID: 25168830.
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    77. Peev V, Reiser J, Alachkar N. Diabetes mellitus in the transplanted kidney. Front Endocrinol (Lausanne). 2014; 5:141. PMID: 25221544.
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    85. Lin CL, Lee PH, Hsu YC, Lei CC, Ko JY, Chuang PC, Huang YT, Wang SY, Wu SL, Chen YS, Chiang WC, Reiser J, Wang FS. MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction. J Am Soc Nephrol. 2014 Aug; 25(8):1698-709. PMID: 24578127.
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    86. Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S. Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. J Clin Invest. 2014 Mar; 124(3):1098-113. PMID: 24531545.
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    89. Reiser J, Fornoni A. Rituximab: a boot to protect the foot. J Am Soc Nephrol. 2014 Apr; 25(4):647-8. PMID: 24459230.
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    93. Müller-Krebs S, Weber L, Tsobaneli J, Kihm LP, Reiser J, Zeier M, Schwenger V. Cellular effects of everolimus and sirolimus on podocytes. PLoS One. 2013; 8(11):e80340. PMID: 24260371.
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    106. Wei C, Trachtman H, Li J, Dong C, Friedman AL, Gassman JJ, McMahan JL, Radeva M, Heil KM, Trautmann A, Anarat A, Emre S, Ghiggeri GM, Ozaltin F, Haffner D, Gipson DS, Kaskel F, Fischer DC, Schaefer F, Reiser J. Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol. 2012 Dec; 23(12):2051-9. PMID: 23138488.
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    107. Schell CB, Kerjaschki D, Reiser J, Huber TB. Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference. Kidney Int. 2012 Nov; 82(10):1041-3. PMID: 23128112.
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    108. Zhang B, Shi W, Ma J, Sloan A, Faul C, Wei C, Reiser J, Yang Y, Liu S, Wang W. The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury. J Mol Med (Berl). 2012 Dec; 90(12):1407-20. PMID: 23015147.
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    109. Mangos S, Amaral AP, Faul C, Jüppner H, Reiser J, Wolf M. Expression of fgf23 and aklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio. Nephrol Dial Transplant. 2012 Dec; 27(12):4314-22. PMID: 22885518.
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    110. Trachtman H, Gipson DS, Kaskel F, Ghiggeri GM, Faul C, Gupta V, Fornoni A, Burke GW, Thomas DB, Barisoni L, Schaefer F, Wei C, Reiser J. Regarding Maas's editorial letter on serum suPAR levels. Kidney Int. 2012 Aug; 82(4):492. PMID: 22846820.
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    112. Chang JW, Pardo V, Sageshima J, Chen L, Tsai HL, Reiser J, Wei C, Ciancio G, Burke GW, Fornoni A. Podocyte foot process effacement in postreperfusion allograft biopsies correlates with early recurrence of proteinuria in focal segmental glomerulosclerosis. Transplantation. 2012 Jun 27; 93(12):1238-44. PMID: 22499148.
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    113. Kistler AD, Altintas MM, Reiser J. Podocyte GTPases regulate kidney filter dynamics. Kidney Int. 2012 Jun; 81(11):1053-5. PMID: 22584591.
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    114. Müller-Krebs S, Kihm LP, Madhusudhan T, Isermann B, Reiser J, Zeier M, Schwenger V. Human RAGE antibody protects against AGE-mediated podocyte dysfunction. Nephrol Dial Transplant. 2012 Aug; 27(8):3129-36. PMID: 22510380.
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    115. Altintas MM, Nayer B, Walford EC, Johnson KB, Gaidosh G, Reiser J, De La Cruz-Munoz N, Ortega LM, Nayer A. Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice. Lipids Health Dis. 2012 Feb 07; 11:21. PMID: 22313574.
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    118. Altintas MM, Rossetti MA, Nayer B, Puig A, Zagallo P, Ortega LM, Johnson KB, McNamara G, Reiser J, Mendez AJ, Nayer A. Apoptosis, mastocytosis, and diminished adipocytokine gene expression accompany reduced epididymal fat mass in long-standing diet-induced obese mice. Lipids Health Dis. 2011 Nov 03; 10:198. PMID: 22051061.
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    119. Mangos S, Reiser J. Fishing for new glomerular disease-related genes. J Am Soc Nephrol. 2011 Nov; 22(11):1960-2. PMID: 21997399.
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    125. Krautkrämer E, Grouls S, Stein N, Reiser J, Zeier M. Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts. J Virol. 2011 Oct; 85(19):9811-23. PMID: 21775443.
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    127. Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest. 2011 May; 121(5):2013-24. PMID: 21540551.
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    128. Wei C, Reiser J. Minimal change disease as a modifiable podocyte paracrine disorder. Nephrol Dial Transplant. 2011 Jun; 26(6):1776-7. PMID: 21414975.
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    129. Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE. Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy. Am J Hum Genet. 2011 Mar 11; 88(3):273-82. PMID: 21353195.
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    130. Reiser J. Filtering new facts about kidney disease. Nat Med. 2011 Jan; 17(1):44-5. PMID: 21217681.
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    133. Papeta N, Zheng Z, Schon EA, Brosel S, Altintas MM, Nasr SH, Reiser J, D'Agati VD, Gharavi AG. Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice. J Clin Invest. 2010 Nov; 120(11):4055-64. PMID: 20978358.
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    134. Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Direct dynamin-actin interactions regulate the actin cytoskeleton. EMBO J. 2010 Nov 03; 29(21):3593-606. PMID: 20935625.
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    135. Reiser J, Adair B, Reinheckel T. Specialized roles for cysteine cathepsins in health and disease. J Clin Invest. 2010 Oct; 120(10):3421-31. PMID: 20921628.
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    136. Krall P, Canales CP, Kairath P, Carmona-Mora P, Molina J, Carpio JD, Ruiz P, Mezzano SA, Li J, Wei C, Reiser J, Young JI, Walz K. Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease. PLoS One. 2010 Sep 20; 5(9):e12859. PMID: 20877463.
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    138. Kistler AD, Reiser J. Maximal 'CD80-uria' with minimal change. Kidney Int. 2010 Aug; 78(3):236-8. PMID: 20631735.
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    139. Chiang WC, Geel TM, Altintas MM, Sever S, Ruiters MH, Reiser J. Establishment of protein delivery systems targeting podocytes. PLoS One. 2010 Jul 29; 5(7):e11837. PMID: 20686602.
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    140. Hauser PV, Pippin JW, Kaiser C, Krofft RD, Brinkkoetter PT, Hudkins KL, Kerjaschki D, Reiser J, Alpers CE, Shankland SJ. Novel siRNA delivery system to target podocytes in vivo. PLoS One. 2010 Mar 01; 5(3):e9463. PMID: 20209128.
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    141. Kistler AD, Peev V, Forst AL, El Hindi S, Altintas MM, Reiser J. Enzymatic disease of the podocyte. Pediatr Nephrol. 2010 Jun; 25(6):1017-23. PMID: 20130922.
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    145. Fornoni A, Jeon J, Varona Santos J, Cobianchi L, Jauregui A, Inverardi L, Mandic SA, Bark C, Johnson K, McNamara G, Pileggi A, Molano RD, Reiser J, Tryggvason K, Kerjaschki D, Berggren PO, Mundel P, Ricordi C. Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release. Diabetes. 2010 Jan; 59(1):190-9. PMID: 19833886.
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    146. Trivedi S, Zeier M, Reiser J. Role of podocytes in lupus nephritis. Nephrol Dial Transplant. 2009 Dec; 24(12):3607-12. PMID: 19729466.
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    148. Faul C, Donnelly M, Merscher-Gomez S, Chang YH, Franz S, Delfgaauw J, Chang JM, Choi HY, Campbell KN, Kim K, Reiser J, Mundel P. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med. 2008 Sep; 14(9):931-8. PMID: 18724379.
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    149. Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22; 283(34):23033-8. PMID: 18562307.
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    150. Möller CC, Mangos S, Drummond IA, Reiser J. Expression of trpC1 and trpC6 orthologs in zebrafish. Gene Expr Patterns. 2008 May; 8(5):291-6. PMID: 18378501.
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    151. Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Modification of kidney barrier function by the urokinase receptor. Nat Med. 2008 Jan; 14(1):55-63. PMID: 18084301.
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    152. Reiser J, Mundel P. Dual effects of RAS blockade on blood pressure and podocyte function. Curr Hypertens Rep. 2007 Nov; 9(5):403-8. PMID: 18177588.
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    155. Yao J, Gutierrez OM, Reiser J. Emphysematous pyelonephritis. Kidney Int. 2007 Mar; 71(5):462-5. PMID: 17136032.
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    158. Asanuma K, Kim K, Oh J, Giardino L, Chabanis S, Faul C, Reiser J, Mundel P. Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J Clin Invest. 2005 May; 115(5):1188-98. PMID: 15841212.
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    159. Reiser J, Mundel P. Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome. J Am Soc Nephrol. 2004 Sep; 15(9):2246-8. PMID: 15339973.
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    160. Reiser J, Oh J, Shirato I, Asanuma K, Hug A, Mundel TM, Honey K, Ishidoh K, Kominami E, Kreidberg JA, Tomino Y, Mundel P. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem. 2004 Aug 13; 279(33):34827-32. PMID: 15197181.
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