David Bennett to Polymorphism, Single Nucleotide
This is a "connection" page, showing publications David Bennett has written about Polymorphism, Single Nucleotide.
Connection Strength
6.442
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Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7.
Score: 0.406
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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Hum Genet. 2022 Jan; 141(1):127-146.
Score: 0.180
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A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3. Genes (Basel). 2021 05 26; 12(6).
Score: 0.173
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Sex differences in the genetic predictors of Alzheimer's pathology. Brain. 2019 09 01; 142(9):2581-2589.
Score: 0.154
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TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits. Am J Hum Genet. 2019 08 01; 105(2):258-266.
Score: 0.152
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Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. Genes Brain Behav. 2019 07; 18(6):e12579.
Score: 0.151
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CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. 2019 08; 18(4):e12964.
Score: 0.151
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Disentangling the genetics of lean mass. Am J Clin Nutr. 2019 02 01; 109(2):276-287.
Score: 0.148
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A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab. 2018 05 01; 103(5):1818-1826.
Score: 0.140
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.
Score: 0.133
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Polygenic risk scores in familial Alzheimer disease. Neurology. 2017 Mar 21; 88(12):1180-1186.
Score: 0.129
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
Score: 0.129
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The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 01 10; 9(1):209-246.
Score: 0.128
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Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. Mol Neurobiol. 2017 Dec; 54(10):8021-8032.
Score: 0.127
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Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2017 02; 13(2):119-129.
Score: 0.126
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Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582.
Score: 0.126
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Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. J Alzheimers Dis. 2016 06 18; 53(3):921-32.
Score: 0.123
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Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 2016 05 26; 533(7604):539-42.
Score: 0.122
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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet. 2016 06; 48(6):624-33.
Score: 0.122
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Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23.
Score: 0.118
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GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP. Brain. 2015 Oct; 138(Pt 10):3076-88.
Score: 0.116
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A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17.
Score: 0.113
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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Mol Psychiatry. 2015 Feb; 20(2):183-92.
Score: 0.112
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Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
Score: 0.110
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Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans. Alzheimers Dement. 2014 Nov; 10(6):609-618.e11.
Score: 0.109
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ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol. 2014; 127(6):825-43.
Score: 0.106
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Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis. 2013; 36(3):181-188.
Score: 0.102
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GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013 Jun 21; 340(6139):1467-71.
Score: 0.100
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GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68.
Score: 0.099
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Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52.
Score: 0.098
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Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory. Neurology. 2012 May 08; 78(19):1464-71.
Score: 0.092
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Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51.
Score: 0.092
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Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8.
Score: 0.085
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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet. 2010 Mar; 42(3):234-9.
Score: 0.079
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Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease. Hum Mol Genet. 2008 Apr 01; 17(7):929-35.
Score: 0.068
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Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease. Neurobiol Aging. 2008 May; 29(5):793-4.
Score: 0.064
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Genetic association of low density lipoprotein receptor and Alzheimer's disease. Neurobiol Aging. 2005 Jan; 26(1):1-7.
Score: 0.056
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The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms. Neurobiol Dis. 2023 01; 176:105938.
Score: 0.048
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Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease. Hum Mol Genet. 2022 09 29; 31(19):3355-3366.
Score: 0.048
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Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease. Biol Psychiatry. 2022 07 01; 92(1):25-33.
Score: 0.045
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The power of genetic diversity in genome-wide association studies of lipids. Nature. 2021 12; 600(7890):675-679.
Score: 0.045
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Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants. PLoS Genet. 2021 11; 17(11):e1009918.
Score: 0.045
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Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia. PLoS Genet. 2021 04; 17(4):e1009482.
Score: 0.043
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Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction. Alzheimers Res Ther. 2021 03 04; 13(1):55.
Score: 0.043
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Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. Transl Psychiatry. 2021 02 26; 11(1):146.
Score: 0.043
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Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nat Genet. 2021 03; 53(3):294-303.
Score: 0.043
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Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021 01 28; 12(1):654.
Score: 0.042
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Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nat Genet. 2021 02; 53(2):143-146.
Score: 0.042
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain. 2020 08 01; 143(8):2561-2575.
Score: 0.041
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Sex-dependent autosomal effects on clinical progression of Alzheimer's disease. Brain. 2020 07 01; 143(7):2272-2280.
Score: 0.041
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Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Neurobiol Aging. 2020 09; 93:61-68.
Score: 0.040
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Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Mol Psychiatry. 2020 11; 25(11):2942-2951.
Score: 0.036
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun. 2018 05 29; 9(1):2098.
Score: 0.035
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Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons. Am J Epidemiol. 2018 05 01; 187(5):933-940.
Score: 0.035
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Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med. 2018 04; 80(3):242-251.
Score: 0.035
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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. Sci Transl Med. 2017 Dec 20; 9(421).
Score: 0.034
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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome. Nat Neurosci. 2017 Oct; 20(10):1418-1426.
Score: 0.033
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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 07 19; 8(1):80.
Score: 0.033
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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. PLoS Med. 2017 04; 14(4):e1002287.
Score: 0.033
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Genetic epistasis regulates amyloid deposition in resilient aging. Alzheimers Dement. 2017 Oct; 13(10):1107-1116.
Score: 0.032
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Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nat Neurosci. 2016 11; 19(11):1442-1453.
Score: 0.031
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. 2016 10; 15(5):792-800.
Score: 0.031
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Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med. 2016 06; 46(8):1613-23.
Score: 0.030
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Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. Medicine (Baltimore). 2015 Nov; 94(47):e1892.
Score: 0.029
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Common variants in DRD2 are associated with sleep duration: the CARe consortium. Hum Mol Genet. 2016 Jan 01; 25(1):167-79.
Score: 0.029
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378.
Score: 0.029
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Genetic variants associated with susceptibility to psychosis in?late-onset Alzheimer's disease families. Neurobiol Aging. 2015 Nov; 36(11):3116.e9-3116.e16.
Score: 0.029
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GSK3? Interactions with Amyloid Genes: An Autopsy Verification and Extension. Neurotox Res. 2015 Oct; 28(3):232-8.
Score: 0.029
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Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement. 2016 Mar; 12(3):233-43.
Score: 0.029
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Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. Alzheimers Dement. 2015 Dec; 11(12):1439-1451.
Score: 0.029
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GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2016 Feb; 21(2):189-197.
Score: 0.028
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The TMEM106B locus and TDP-43 pathology in older persons without FTLD. Neurology. 2015 Mar 03; 84(9):927-34.
Score: 0.028
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Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16.
Score: 0.028
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FASTKD2 is associated with memory and hippocampal structure in older adults. Mol Psychiatry. 2015 Oct; 20(10):1197-204.
Score: 0.028
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Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.
Score: 0.027
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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.
Score: 0.027
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Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol. 2014 Apr; 71(4):429-35.
Score: 0.026
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CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility. Hum Mol Genet. 2014 May 15; 23(10):2729-36.
Score: 0.026
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The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan. Mol Psychiatry. 2014 Oct; 19(10):1125-32.
Score: 0.026
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8.
Score: 0.026
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Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013 Aug 22; 500(7463):477-81.
Score: 0.025
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Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013 Apr 10; 309(14):1483-92.
Score: 0.025
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A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78.
Score: 0.024
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Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8.
Score: 0.023
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Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. Am J Hum Genet. 2012 Apr 06; 90(4):720-6.
Score: 0.023
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A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline. Hum Mol Genet. 2012 May 15; 21(10):2377-88.
Score: 0.023
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Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology. 2012 Jan 31; 78(5):334-41.
Score: 0.023
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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.
Score: 0.021
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CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol. 2011 Mar; 69(3):560-9.
Score: 0.021
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Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet. 2011 Feb; 7(2):e1001308.
Score: 0.021
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Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84.
Score: 0.021
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Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One. 2010 Jun 21; 5(6):e11244.
Score: 0.020
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Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301.
Score: 0.020
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Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiol Aging. 2011 Dec; 32(12):2113-22.
Score: 0.020
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Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 05; 134B(1):1-5.
Score: 0.014