Anesthetics, Local
"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Descriptor ID |
D000779
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MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
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Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
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Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1991 | 1 | 0 | 1 | 1997 | 0 | 1 | 1 | 1998 | 2 | 0 | 2 | 1999 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2002 | 2 | 0 | 2 | 2003 | 3 | 1 | 4 | 2004 | 2 | 1 | 3 | 2005 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2007 | 1 | 2 | 3 | 2008 | 1 | 0 | 1 | 2009 | 4 | 2 | 6 | 2010 | 2 | 0 | 2 | 2011 | 2 | 2 | 4 | 2012 | 4 | 2 | 6 | 2013 | 2 | 0 | 2 | 2014 | 2 | 2 | 4 | 2016 | 6 | 2 | 8 | 2017 | 3 | 0 | 3 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
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Simon DP, Bajic P, Lynch KM, Levine LA. Spermatic Cord Block Series as a Minimally Invasive Therapy for Chronic Scrotal Content Pain. J Urol. 2021 Sep; 206(3):725-732.
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Ende HB, Tran B, Thampy M, Bauchat JR, McCarthy RJ. Standardization of epidural top-ups for breakthrough labor pain results in a higher proportion of catheter replacements within 30?min of the first bolus dose. Int J Obstet Anesth. 2021 08; 47:103161.
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Reader RC, McCarthy RJ, Schultz KL, Volturo AR, Barton BA, O'Hara MJ, Abelson AL. Comparison of liposomal bupivacaine and 0.5% bupivacaine hydrochloride for control of postoperative pain in dogs undergoing tibial plateau leveling osteotomy. J Am Vet Med Assoc. 2020 May 01; 256(9):1011-1019.
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Jorgenson K, Burbridge L, Cole B. Comparison of the efficacy of a standard inferior alveolar nerve block versus articaine infiltration for invasive dental treatment in permanent mandibular molars in children: a pilot study. Eur Arch Paediatr Dent. 2020 Feb; 21(1):171-177.
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Lange EMS, Wong CA, Fitzgerald PC, Davila WF, Rao S, McCarthy RJ, Toledo P. Effect of Epidural Infusion Bolus Delivery Rate on the Duration of Labor Analgesia: A Randomized Clinical Trial. Anesthesiology. 2018 04; 128(4):745-753.
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McCormick ZL, Nelson A, Kendall MC, McCarthy RJ, Nagpal G, Walega DR. Does Cervical Interlaminar Epidural Steroid Injection with Low-Dose Lidocaine Cause Objective Upper Extremity Weakness? A Preliminary Study. Pain Med. 2017 Dec 01; 18(12):2296-2305.
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Chalifoux LA, Bauchat JR, Higgins N, Toledo P, Peralta FM, Farrer J, Gerber SE, McCarthy RJ, Sullivan JT. Effect of Intrathecal Bupivacaine Dose on the Success of External Cephalic Version for Breech Presentation: A Prospective, Randomized, Blinded Clinical Trial. Anesthesiology. 2017 10; 127(4):625-632.
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Kendall MC, McCarthy RJ, Panaro S, Goodwin E, Bialek JM, Nader A, De Oliveira GS. The Effect of Intraoperative Systemic Lidocaine on Postoperative Persistent Pain Using Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials Criteria Assessment Following Breast Cancer Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial. Pain Pract. 2018 03; 18(3):350-359.
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Kroin JS, Li J, Moric M, Birmingham BW, Tuman KJ, Buvanendran A. Local Infiltration of Analgesics at Surgical Wound to Reduce Postoperative Pain After Laparotomy in Rats. Reg Anesth Pain Med. 2016 Nov/Dec; 41(6):691-695.
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Nader A, Kendall MC, Manning DW, Beal M, Rahangdale R, Dekker R, De Oliveira GS, Kamenetsky E, McCarthy RJ. Single-Dose Adductor Canal Block With Local Infiltrative Analgesia Compared With Local Infiltrate Analgesia After Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial. Reg Anesth Pain Med. 2016 Nov-Dec; 41(6):678-684.
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