 Receptor, Insulin
"Receptor, Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.
| Descriptor ID |
D011972
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.200 D12.776.543.750.060.484 D12.776.543.750.750.580.300
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| Concept/Terms |
Receptor, Insulin- Receptor, Insulin
- Insulin Receptor Protein-Tyrosine Kinase
- Insulin Receptor Protein Tyrosine Kinase
- Receptors, Insulin
- Insulin Receptors
- Insulin Receptor
- Insulin-Dependent Tyrosine Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Receptor, Insulin".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Insulin".
This graph shows the total number of publications written about "Receptor, Insulin" by people in this website by year, and whether "Receptor, Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Insulin" by people in Profiles.
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Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015 Mar 10; 6:6496.
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Nakanishi Y, Mulshine JL, Kasprzyk PG, Natale RB, Maneckjee R, Avis I, Treston AM, Gazdar AF, Minna JD, Cuttitta F. Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro. J Clin Invest. 1988 Jul; 82(1):354-9.
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Baldwin D, Winston E, Hoshizaki RJ, Garland JT, Baldwin D, Holcomb HH, Flier JS, Rubenstein A. Insulin-resistant diabetes with insulin receptor autoantibodies in a male patient without acanghosis nigricans. Diabetes Care. 1979 May-Jun; 2(3):275-7.
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