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MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation.
Picobirnavirus
Paun, Olimpia
Epstein, Rachel
LIFE and ARBITER.
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LIFE and ARBITER.
LIFE and ARBITER. Prev Cardiol. 2003; 6(2):108-11.
View in:
PubMed
subject areas
Adrenergic beta-Antagonists
Antihypertensive Agents
Atenolol
Carotid Artery Diseases
Cholesterol, LDL
Heptanoic Acids
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypertension
Hypertrophy, Left Ventricular
Losartan
Pravastatin
Pyrroles
Treatment Outcome