 Intervertebral Disc Chemolysis
"Intervertebral Disc Chemolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dissolving of the nucleus pulposus, the semi-gelatinous tissue of a displaced INTERVERTEBRAL DISC. It is usually achieved by the direct injection of a proteolytic enzyme, especially CHYMOPAPAIN, into the herniated disc.
| Descriptor ID |
D007404
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| MeSH Number(s) |
E02.718.500
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| Concept/Terms |
Intervertebral Disc Chemolysis- Intervertebral Disc Chemolysis
- Chemolyses, Intervertebral Disc
- Disc Chemolyses, Intervertebral
- Disc Chemolysis, Intervertebral
- Intervertebral Disc Chemolyses
- Chemolysis, Intervertebral Disk
- Chemonucleolysis
- Chemonucleolyses
- Intervertebral Disk Chemolysis
- Chemolyses, Intervertebral Disk
- Disk Chemolyses, Intervertebral
- Disk Chemolysis, Intervertebral
- Intervertebral Disk Chemolyses
- Nucleolysis, Intervertebral Disc
- Disc Nucleolyses, Intervertebral
- Disc Nucleolysis, Intervertebral
- Intervertebral Disc Nucleolyses
- Intervertebral Disc Nucleolysis
- Nucleolyses, Intervertebral Disc
- Nucleolysis, Intervertebral Disk
- Disk Nucleolyses, Intervertebral
- Disk Nucleolysis, Intervertebral
- Intervertebral Disk Nucleolyses
- Intervertebral Disk Nucleolysis
- Nucleolyses, Intervertebral Disk
- Chemolysis, Intervertebral Disc
- Discolysis
- Discolyses
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Below are MeSH descriptors whose meaning is more general than "Intervertebral Disc Chemolysis".
Below are MeSH descriptors whose meaning is more specific than "Intervertebral Disc Chemolysis".
This graph shows the total number of publications written about "Intervertebral Disc Chemolysis" by people in this website by year, and whether "Intervertebral Disc Chemolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Intervertebral Disc Chemolysis" by people in Profiles.
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Imai Y, Okuma M, An HS, Nakagawa K, Yamada M, Muehleman C, Thonar E, Masuda K. Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC. Spine (Phila Pa 1976). 2007 May 15; 32(11):1197-205.
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Takegami K, An HS, Kumano F, Chiba K, Thonar EJ, Singh K, Masuda K. Osteogenic protein-1 is most effective in stimulating nucleus pulposus and annulus fibrosus cells to repair their matrix after chondroitinase ABC-induced in vitro chemonucleolysis. Spine J. 2005 May-Jun; 5(3):231-8.
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Fessler RG, Sandhu FA. Minimalism: is less more? Clin Neurosurg. 2003; 50:220-7.
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Block JA, Schnitzer TJ, Andersson GB, Lenz ME, Jeffery R, McNeill TW, Thonar EJ. The effect of chemonucleolysis on serum keratan sulfate levels in humans. Arthritis Rheum. 1989 Jan; 32(1):100-4.
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