Complement System Proteins
"Complement System Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).
Descriptor ID |
D003165
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MeSH Number(s) |
D12.776.124.486.274
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Concept/Terms |
Complement System Proteins- Complement System Proteins
- Proteins, Complement System
- Complement Protein
- Protein, Complement
- Complement Proteins
- Proteins, Complement
- Complement
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Below are MeSH descriptors whose meaning is more general than "Complement System Proteins".
Below are MeSH descriptors whose meaning is more specific than "Complement System Proteins".
This graph shows the total number of publications written about "Complement System Proteins" by people in this website by year, and whether "Complement System Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1987 | 0 | 1 | 1 | 1990 | 1 | 1 | 2 | 1991 | 1 | 0 | 1 | 1992 | 1 | 1 | 2 | 1996 | 1 | 0 | 1 | 1997 | 0 | 1 | 1 | 1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement System Proteins" by people in Profiles.
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Bao L, Perez White BE, Li J, Patel PM, Amber KT. Gene expression profiling of laminin a3-blocked keratinocytes reveals an immune-independent mechanism of blistering. Exp Dermatol. 2022 04; 31(4):615-621.
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Bektas M, Copley-Merriman C, Khan S, Sarda SP, Shammo JM. Paroxysmal nocturnal hemoglobinuria: role of the complement system, pathogenesis, and pathophysiology. J Manag Care Spec Pharm. 2020 Dec; 26(12-b Suppl):S3-S8.
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Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. J Biol Chem. 2013 Dec 20; 288(51):36598-609.
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Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC. Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. PLoS One. 2013; 8(4):e60838.
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Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV. A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus. J Biol Chem. 2010 Aug 06; 285(32):24729-39.
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Ji X, Olinger GG, Aris S, Chen Y, Gewurz H, Spear GT. Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization. J Gen Virol. 2005 Sep; 86(Pt 9):2535-2542.
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Spear GT, Olinger GG, Saifuddin M, Gebel HM. Human antibodies to major histocompatibility complex alloantigens mediate lysis and neutralization of HIV-1 primary isolate virions in the presence of complement. J Acquir Immune Defic Syndr. 2001 Feb 01; 26(2):103-10.
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Spear GT, Hart M, Olinger GG, Hashemi FB, Saifuddin M. The role of the complement system in virus infections. Curr Top Microbiol Immunol. 2001; 260:229-45.
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Spear GT, Olinger G, Sullivan BL, Landay AL, Kessler H, Connick E, Kuritzkes D, St Clair M, Spritzler J, Wu H, Lederman MM. Alteration of complement protein levels after antiretroviral therapy in HIV-infected persons. AIDS Res Hum Retroviruses. 1999 Dec 10; 15(18):1713-5.
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Jakubik JJ, Saifuddin M, Takefman DM, Spear GT. B lymphocytes in lymph nodes and peripheral blood are important for binding immune complexes containing HIV-1. Immunology. 1999 Apr; 96(4):612-9.
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