 Genes, ras
"Genes, ras" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
| Descriptor ID |
D011905
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| MeSH Number(s) |
G05.360.340.024.340.375.500.791.550
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| Concept/Terms |
N-ras Genes- N-ras Genes
- Genes, N-ras
- N ras Genes
- N-ras Gene
- N-ras Oncogenes
- N ras Oncogenes
- N-ras Oncogene
v-Ha-ras Genes- v-Ha-ras Genes
- Gene, v-Ha-ras
- Genes, v-Ha-ras
- v Ha ras Genes
- v-Ha-ras Gene
v-Ki-ras Genes- v-Ki-ras Genes
- Gene, v-Ki-ras
- Genes, v-Ki-ras
- v Ki ras Genes
- v-Ki-ras Gene
Ha-ras Genes- Ha-ras Genes
- Gene, Ha-ras
- Genes, Ha-ras
- Ha ras Genes
- Ha-ras Gene
Ki-ras Genes- Ki-ras Genes
- Gene, Ki-ras
- Genes, Ki-ras
- Ki ras Genes
- Ki-ras Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, ras".
Below are MeSH descriptors whose meaning is more specific than "Genes, ras".
This graph shows the total number of publications written about "Genes, ras" by people in this website by year, and whether "Genes, ras" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 1 | 1 | 2 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, ras" by people in Profiles.
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Filicori F, Keutgen XM, Buitrago D, AlDailami H, Crowley M, Fahey TJ, Zarnegar R. Risk stratification of indeterminate thyroid fine-needle aspiration biopsy specimens based on mutation analysis. Surgery. 2011 Dec; 150(6):1085-91.
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Mahdavinia M, Bishehsari F, Verginelli F, Cumashi A, Lattanzio R, Sotoudeh M, Ansari R, Semeraro D, Hormazdi M, Fakheri H, Rakhshani N, De Lellis L, Curia MC, Cama A, Piantelli M, Malekzadeh R, Iacobelli S, Mariani-Costantini R. P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations. J Cell Physiol. 2008 Aug; 216(2):543-50.
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Konishi H, Karakas B, Abukhdeir AM, Lauring J, Gustin JP, Garay JP, Konishi Y, Gallmeier E, Bachman KE, Park BH. Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation. Cancer Res. 2007 Sep 15; 67(18):8460-7.
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Bishehsari F, Mahdavinia M, Malekzadeh R, Verginelli F, Catalano T, Sotoudeh M, Bazan V, Agnese V, Esposito DL, De Lellis L, Semeraro D, Colucci G, Hormazdi M, Rakhshani N, Cama A, Piantelli M, Iacobelli S, Russo A, Mariani-Costantini R. Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin. Ann Oncol. 2006 Jun; 17 Suppl 7:vii91-6.
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Xu X, Rao G, Gaffud MJ, Ding HG, Maki G, Klingemann HG, Groh V, Spies T, Caillat-Zucman S, Gattuso P, Plate J, Prinz RA. Clinicopathological significance of major histocompatibility complex class I-related chain a and B expression in thyroid cancer. J Clin Endocrinol Metab. 2006 Jul; 91(7):2704-12.
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MartÃnez A, Lehman TA, Modali R, Mulshine JL. Screening of mutations in the ras family of oncogenes by polymerase chain reaction-based ligase chain reaction. Methods Mol Med. 2003; 74:187-200.
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Shi M, Dennis K, Peschon JJ, Chandrasekaran R, Mikecz K. Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton. J Immunol. 2001 Jul 01; 167(1):123-31.
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Tockman MS, Mulshine JL. The early detection of occult lung cancer. Chest Surg Clin N Am. 2000 Nov; 10(4):737-49.
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Scott FM, Modali R, Lehman TA, Seddon M, Kelly K, Dempsey EC, Wilson V, Tockman MS, Mulshine JL. High frequency of K-ras codon 12 mutations in bronchoalveolar lavage fluid of patients at high risk for second primary lung cancer. Clin Cancer Res. 1997 Mar; 3(3):479-82.
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Lehman TA, Scott F, Seddon M, Kelly K, Dempsey EC, Wilson VL, Mulshine JL, Modali R. Detection of K-ras oncogene mutations by polymerase chain reaction-based ligase chain reaction. Anal Biochem. 1996 Aug 01; 239(2):153-9.
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