 Tryptophan
"Tryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
| Descriptor ID |
D014364
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| MeSH Number(s) |
D12.125.072.050.850 D12.125.142.875
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| Concept/Terms |
Tryptophan- Tryptophan
- Levotryptophan
- L-Tryptophan
- L Tryptophan
Ardeydorm- Ardeydorm
- Ardeytropin
- Ardeypharm Brand of Tryptophan
L-Tryptophan-ratiopharm- L-Tryptophan-ratiopharm
- L Tryptophan ratiopharm
- Ratiopharm Brand of Tryptophan
- ratio-Tryptophan
- ratio Tryptophan
PMS-Tryptophan- PMS-Tryptophan
- PMS Tryptophan
- Pharmascience Brand of Tryptophan
Trofan- Trofan
- Upsher-Smith Brand of Tryptophan
Optimax- Optimax
- Merck Brand of Tryptophan
Lyphan- Lyphan
- Naturruhe
- esparma Brand of Tryptophan
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Below are MeSH descriptors whose meaning is more general than "Tryptophan".
Below are MeSH descriptors whose meaning is more specific than "Tryptophan".
This graph shows the total number of publications written about "Tryptophan" by people in this website by year, and whether "Tryptophan" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Tryptophan" by people in Profiles.
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Qi Q, Hua S, Clish CB, Scott JM, Hanna DB, Wang T, Haberlen SA, Shah SJ, Glesby MJ, Lazar JM, Burk RD, Hodis HN, Landay AL, Post WS, Anastos K, Kaplan RC. Plasma Tryptophan-Kynurenine Metabolites Are Altered in Human Immunodeficiency Virus Infection and Associated With Progression of Carotid Artery Atherosclerosis. Clin Infect Dis. 2018 07 02; 67(2):235-242.
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Petersen J, Christensen KE, Nielsen MT, Mortensen KT, Komnatnyy VV, Nielsen TE, Qvortrup K. Oxidative Modification of Tryptophan-Containing Peptides. ACS Comb Sci. 2018 06 11; 20(6):344-349.
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Cherny VV, Morgan D, Musset B, Chaves G, Smith SM, DeCoursey TE. Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1. J Gen Physiol. 2015 Nov; 146(5):343-56.
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Lamar M, Craig M, Daly EM, Cutter WJ, Tang C, Brammer M, Rubia K, Murphy DG. Acute tryptophan depletion promotes an anterior-to-posterior fMRI activation shift during task switching in older adults. Hum Brain Mapp. 2014 Feb; 35(2):712-22.
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Daly EM, Deeley Q, Ecker C, Craig M, Hallahan B, Murphy C, Johnston P, Spain D, Gillan N, Brammer M, Giampietro V, Lamar M, Page L, Toal F, Cleare A, Surguladze S, Murphy DG. Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion. Arch Gen Psychiatry. 2012 Oct; 69(10):1003-13.
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Daly E, Deeley Q, Hallahan B, Craig M, Brammer M, Lamar M, Cleare A, Giampietro V, Ecker C, Page L, Toal F, Phillips ML, Surguladze S, Murphy DG. Effects of acute tryptophan depletion on neural processing of facial expressions of emotion in humans. Psychopharmacology (Berl). 2010 Jul; 210(4):499-510.
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Pagoto SL, Spring B, McChargue D, Hitsman B, Smith M, Appelhans B, Hedeker D. Acute tryptophan depletion and sweet food consumption by overweight adults. Eat Behav. 2009 Jan; 10(1):36-41.
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Lamar M, Cutter WJ, Rubia K, Brammer M, Daly EM, Craig MC, Cleare AJ, Murphy DG. 5-HT, prefrontal function and aging: fMRI of inhibition and acute tryptophan depletion. Neurobiol Aging. 2009 Jul; 30(7):1135-46.
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Szántó S, Koreny T, Mikecz K, Glant TT, Szekanecz Z, Varga J. Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice. Arthritis Res Ther. 2007; 9(3):R50.
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Spring B, Hitsman B, Pingitore R, McChargue DE, Gunnarsdottir D, Corsica J, Pergadia M, Doran N, Crayton JW, Baruah S, Hedeker D. Effect of tryptophan depletion on smokers and nonsmokers with and without history of major depression. Biol Psychiatry. 2007 Jan 01; 61(1):70-7.
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