 Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
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| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.641.600.100 D23.529.850.100
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| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
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Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1994 | 0 | 1 | 1 | | 1996 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 2 | 1 | 3 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.
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Voigt RM, Raeisi S, Yang J, Leurgans S, Forsyth CB, Buchman AS, Bennett DA, Keshavarzian A. Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease. PLoS One. 2021; 16(3):e0240342.
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Fransquet PD, Lacaze P, Saffery R, Phung J, Parker E, Shah RC, Murray A, Woods RL, Ryan J. DNA methylation analysis of candidate genes associated with dementia in peripheral blood. Epigenomics. 2020 12; 12(23):2109-2123.
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Halloway S, Jung M, Yeh AY, Liu J, McAdams E, Barley M, Dorsey SG, Pressler SJ. An Integrative Review of Brain-Derived Neurotrophic Factor and Serious Cardiovascular Conditions. Nurs Res. 2020 Sep/Oct; 69(5):376-390.
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Patel D, Roy A, Raha S, Kundu M, Gonzalez FJ, Pahan K. Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARa. JCI Insight. 2020 05 21; 5(10).
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Fisher DW, Bennett DA, Dong H. Sexual dimorphism in predisposition to Alzheimer's disease. Neurobiol Aging. 2018 10; 70:308-324.
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Felsky D, Xu J, Chibnik LB, Schneider JA, Knight J, Kennedy JL. Genetic epistasis regulates amyloid deposition in resilient aging. Alzheimers Dement. 2017 Oct; 13(10):1107-1116.
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Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA. Higher brain BDNF gene expression is associated with slower cognitive decline in older adults. Neurology. 2016 Feb 23; 86(8):735-41.
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Li M, Armelloni S, Zennaro C, Wei C, Corbelli A, Ikehata M, Berra S, Giardino L, Mattinzoli D, Watanabe S, Agostoni C, Edefonti A, Reiser J, Messa P, Rastaldi MP. BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44.
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D'Mello SR, Elangovan S, Hong L, Ross RD, Sumner DR, Salem AK. A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects. Curr Pharm Biotechnol. 2015; 16(7):655-60.
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Corbett GT, Roy A, Pahan K. Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. J Biol Chem. 2013 Mar 22; 288(12):8299-8312.
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