"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
|
| MeSH Number(s) |
G12.535.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Lung Injury and Loss of Regulatory T Cells Primes for Lung-Restricted Autoimmunity. Crit Rev Immunol. 2017; 37(1):23-37.
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Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs. Sci Transl Med. 2015 May 27; 7(289):289ra81.
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Neonatal immune-tolerance in mice does not prevent xenograft rejection. Exp Neurol. 2014 Apr; 254:90-8.
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Immune responses in liver-directed lentiviral gene therapy. Transl Res. 2013 Apr; 161(4):230-40.
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Intestinal epithelial cell-derived integrin aß6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response. J Leukoc Biol. 2011 Oct; 90(4):751-9.