Amphetamine
"Amphetamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
Descriptor ID |
D000661
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MeSH Number(s) |
D02.092.471.683.152.110
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Concept/Terms |
Amphetamine- Amphetamine
- Desoxynorephedrin
- Phenopromin
- Amfetamine
- Phenamine
Centramina- Centramina
- Miquel Brand of Amfetamine Sulfate
l-Amphetamine- l-Amphetamine
- l Amphetamine
- Levoamphetamine
- levo-Amphetamine
- levo Amphetamine
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Below are MeSH descriptors whose meaning is more general than "Amphetamine".
Below are MeSH descriptors whose meaning is more specific than "Amphetamine".
This graph shows the total number of publications written about "Amphetamine" by people in this website by year, and whether "Amphetamine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1983 | 0 | 1 | 1 | 2002 | 2 | 0 | 2 | 2006 | 3 | 0 | 3 | 2007 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amphetamine" by people in Profiles.
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Levine LA, Betcher HK, Ziegelmann MJ, Bajic P. Amphetamine/Dextroamphetamine Salts for Delayed Orgasm and Anorgasmia in Men: A Pilot Study. Urology. 2020 08; 142:141-145.
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Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. J Neurosci. 2014 Mar 26; 34(13):4519-27.
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Riccardi P, Park S, Anderson S, Doop M, Ansari MS, Schmidt D, Baldwin R. Sex differences in the relationship of regional dopamine release to affect and cognitive function in striatal and extrastriatal regions using positron emission tomography and [ยน8F]fallypride. Synapse. 2011 Feb; 65(2):99-102.
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Rademacher DJ, Napier TC, Meredith GE. Context modulates the expression of conditioned motor sensitization, cellular activation and synaptophysin immunoreactivity. Eur J Neurosci. 2007 Nov; 26(9):2661-8.
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Shen F, Meredith GE, Napier TC. Amphetamine-induced place preference and conditioned motor sensitization requires activation of tyrosine kinase receptors in the hippocampus. J Neurosci. 2006 Oct 25; 26(43):11041-51.
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Rademacher DJ, Kovacs B, Shen F, Napier TC, Meredith GE. The neural substrates of amphetamine conditioned place preference: implications for the formation of conditioned stimulus-reward associations. Eur J Neurosci. 2006 Oct; 24(7):2089-97.
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Riccardi P, Li R, Ansari MS, Zald D, Park S, Dawant B, Anderson S, Doop M, Woodward N, Schoenberg E, Schmidt D, Baldwin R, Kessler R. Amphetamine-induced displacement of [18F] fallypride in striatum and extrastriatal regions in humans. Neuropsychopharmacology. 2006 May; 31(5):1016-26.
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Weinshenker D, Miller NS, Blizinsky K, Laughlin ML, Palmiter RD. Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13873-7.
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Hu XT, Koeltzow TE, Cooper DC, Robertson GS, White FJ, Vezina P. Repeated ventral tegmental area amphetamine administration alters dopamine D1 receptor signaling in the nucleus accumbens. Synapse. 2002 Sep 01; 45(3):159-70.
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Goetz CG, Klawans HL, Carvey P. Animal models of tardive dyskinesia: their use in the search for new treatment methods. Mod Probl Pharmacopsychiatry. 1983; 21:5-20.
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