 Off-Label Use
"Off-Label Use" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
| Descriptor ID |
D056687
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| MeSH Number(s) |
E02.319.307.500
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| Concept/Terms |
Off-Label Use- Off-Label Use
- Off Label Use
- Off-Label Uses
- Use, Off-Label
- Uses, Off-Label
- Off-Label Prescribing
- Off Label Prescribing
- Off-Label Prescribings
- Prescribing, Off-Label
- Prescribings, Off-Label
- Unlabeled Indication
- Indication, Unlabeled
- Indications, Unlabeled
- Unlabeled Indications
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Below are MeSH descriptors whose meaning is more general than "Off-Label Use".
Below are MeSH descriptors whose meaning is more specific than "Off-Label Use".
This graph shows the total number of publications written about "Off-Label Use" by people in this website by year, and whether "Off-Label Use" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 3 | 3 | | 2014 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Off-Label Use" by people in Profiles.
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Greenberg SM, Cordonnier C, Schneider JA, Smith EE, van Buchem MA, van Veluw SJ, Verbeek MM, Viswanathan A, Werring DJ. Off-label use of aducanumab for cerebral amyloid angiopathy. Lancet Neurol. 2021 08; 20(8):596-597.
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Deer T, Kim P, Pope JE, Hayek S, McDowell G, Mekhail N, Diwan S, Saulino M, Moeschler S, Schultz D, Gritsenko K, Prager J, Peterson EA, Staats P, Poree L, Fishman MA, Vallejo R, Calodney A, Slavin K, de Leon Cassadala O, Levy R, Buvanendran A, Sitzman BT, Sayed D, Ferrante FM, Kloth D, Gilligan CJ, Kapural L, Kloster DR, Leong M, Rosenow JM, Lamer TJ, Stearns L. Physician Guidance on the Use of Off-Labeled Drugs in Intrathecal Drug Delivery Systems for Chronic Pain. Neuromodulation. 2019 10; 22(7):765-768.
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Aronsohn A, Reau N, Jensen D. Preparing for the uncertain yet inevitable: off-label combinations of antiviral agents in hepatitis C virus. Hepatology. 2014 May; 59(5):1688-91.
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Avery RK, Mossad SB, Poggio E, Lard M, Budev M, Bolwell B, Waldman WJ, Braun W, Mawhorter SD, Fatica R, Krishnamurthi V, Young JB, Shrestha R, Stephany B, Lurain N, Yen-Lieberman B. Utility of leflunomide in the treatment of complex cytomegalovirus syndromes. Transplantation. 2010 Aug 27; 90(4):419-26.
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Bezerra H, Perin E, Berger P, Block P, Ramee S, Katz S, Kellet M, Dippel E, Schaer G, Britto S, Cohen S, Costa M. Outcomes of unselected recipients of sirolimus-eluting stents: the Cypher stent U.S. post-marketing surveillance registry. J Invasive Cardiol. 2010 Feb; 22(2):48-55.
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Traynelis VC. Ectopic bone. J Neurosurg Spine. 2010 Jan; 12(1):39.
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