Pyrimethamine
"Pyrimethamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Descriptor ID |
D011739
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MeSH Number(s) |
D03.383.742.675
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Concept/Terms |
Malocide- Malocide
- Aventis Brand of Pyrimethamine
Daraprim- Daraprim
- GlaxoSmithKline Brand of Pyrimethamine
- Wellcome Brand of Pyrimethamine
- Glaxo Wellcome Brand of Pyrimethamine
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Below are MeSH descriptors whose meaning is more general than "Pyrimethamine".
Below are MeSH descriptors whose meaning is more specific than "Pyrimethamine".
This graph shows the total number of publications written about "Pyrimethamine" by people in this website by year, and whether "Pyrimethamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1990 | 0 | 1 | 1 | 1992 | 1 | 0 | 1 | 1994 | 0 | 1 | 1 | 1995 | 1 | 0 | 1 | 1996 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2006 | 0 | 2 | 2 | 2007 | 0 | 2 | 2 | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrimethamine" by people in Profiles.
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Benevento JD, Jager RD, Noble AG, Latkany P, Mieler WF, Sautter M, Meyers S, Mets M, Grassi MA, Rabiah P, Boyer K, Swisher C, McLeod R. Toxoplasmosis-associated neovascular lesions treated successfully with ranibizumab and antiparasitic therapy. Arch Ophthalmol. 2008 Aug; 126(8):1152-6.
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Arun V, Noble AG, Latkany P, Troia RN, Jalbrzikowski J, Kasza K, Karrison T, Cezar S, Sautter M, Greenwald MJ, Mieler W, Mets MB, Alam A, Boyer K, Swisher CN, Roizen N, Rabiah P, Del Monte MA, McLeod R. Cataracts in congenital toxoplasmosis. J AAPOS. 2007 Dec; 11(6):551-4.
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Phan L, Kasza K, Jalbrzikowski J, Noble AG, Latkany P, Kuo A, Mieler W, Meyers S, Rabiah P, Boyer K, Swisher C, Mets M, Roizen N, Cezar S, Remington J, Meier P, McLeod R. Longitudinal study of new eye lesions in treated congenital toxoplasmosis. Ophthalmology. 2008 Mar; 115(3):553-559.e8.
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McLeod R, Boyer K, Karrison T, Kasza K, Swisher C, Roizen N, Jalbrzikowski J, Remington J, Heydemann P, Noble AG, Mets M, Holfels E, Withers S, Latkany P, Meier P. Outcome of treatment for congenital toxoplasmosis, 1981-2004: the National Collaborative Chicago-Based, Congenital Toxoplasmosis Study. Clin Infect Dis. 2006 May 15; 42(10):1383-94.
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McLeod R, Khan AR, Noble GA, Latkany P, Jalbrzikowski J, Boyer K. Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. Pediatr Infect Dis J. 2006 Mar; 25(3):270-2.
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McLeod R, Boyer K, Roizen N, Stein L, Swisher C, Holfels E, Hopkins J, Mack D, Karrison T, Patel D, Pfiffner L, Remington J, Withers S, Meyers S, Aitchison V, Mets M, Rabiah P, Meier P. The child with congenital toxoplasmosis. Curr Clin Top Infect Dis. 2000; 20:189-208.
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Patel DV, Holfels EM, Vogel NP, Boyer KM, Mets MB, Swisher CN, Roizen NJ, Stein LK, Stein MA, Hopkins J, Withers SE, Mack DG, Luciano RA, Meier P, Remington JS, McLeod RL. Resolution of intracranial calcifications in infants with treated congenital toxoplasmosis. Radiology. 1996 May; 199(2):433-40.
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Roizen N, Swisher CN, Stein MA, Hopkins J, Boyer KM, Holfels E, Mets MB, Stein L, Patel D, Meier P, et al. Neurologic and developmental outcome in treated congenital toxoplasmosis. Pediatrics. 1995 Jan; 95(1):11-20.
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McAuley J, Boyer KM, Patel D, Mets M, Swisher C, Roizen N, Wolters C, Stein L, Stein M, Schey W, et al. Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial. Clin Infect Dis. 1994 Jan; 18(1):38-72.
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McLeod R, Mack D, Foss R, Boyer K, Withers S, Levin S, Hubbell J. Levels of pyrimethamine in sera and cerebrospinal and ventricular fluids from infants treated for congenital toxoplasmosis. Toxoplasmosis Study Group. Antimicrob Agents Chemother. 1992 May; 36(5):1040-8.
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